Treatment of cancer of the ovary.

This chapter has stressed the importance of early diagnosis in the treatment of cancer of the ovary with suggestions as to achieving this goal by a more aggressive approach to the accurate diagnosis of pelvic tumours. The combined use of surgery with radiation therapy and/or chemotherapy has also been discussed with the definition of the functions of the surgeon, radiotherapist and chemotherapist. The place of surgery in the staging and initial treatment of this disease is outlined and the indications for surgery for advanced and recurrent disease are demonstrated. The use of the various modalities of ionising radiation has been outlined and the place of chemotherapy and selection of appropriate drugs are also discussed.     

复发性宫颈癌的治疗

宫颈癌是世界范围内最常见的女性生殖系统恶性肿瘤,严重威胁女性的生命。在发展中国家占女性癌症死亡率的第二位。宫颈癌治疗失败的主要原因是局部复发和远处转移。复发性宫颈癌患者预后差、5年生存率低。因此,复发性宫颈癌的治疗成为临床关注的重点。     

Treatment of fallopian tube cancer

Objective: To contribute toward the understanding of the therapeutic management of fallopian tube cancer. Methods: Recent studies related to the treatment of fallopian tube cancer were reviewed. Results: Current evidence indicates that even patients in early stages have nodal disease, and often experience relapses in distant sites. In advanced stages, survival prolongation by the use of platinum-based chemotherapy has been demonstrated. Aggressive cytoreductive surgery followed by chemotherapy and negative second-look laparotomy offer the possibility of long-term survival. However, a significant fraction of patients eventually relapses after negative second-look laparotomy, and a poor survival rate after positive second-look laparotomy has been observed. Conclusions: This series suggests the need for thorough evaluation of lymph nodes at the time of surgery. The use of platinum-based chemotherapy is probably the best adjuvant therapy for both early stages and advanced stages. The clinical value of second-look laparotomy will remain limited until effective salvage therapy is developed. The potential benefits of neoadjuvant chemotherapy and the use of paclitaxel will be increasingly important. Received: August 1999 / Accepted: 23 December 1999     

复发性子宫内膜癌综合治疗

子宫内膜癌初始手术和(或)放疗后复发率相对较低,因此国内外关于复发性子宫内膜癌治疗的相关文献较少。临床上对复发性子宫内膜癌患者具体治疗方案的抉择需要根据复发癌灶的部位、初始治疗方式以及患者身体状态采取个体化综合治疗的处理方式。该文结合2012年美国国立综合癌症网(NCCN)子宫内膜癌临床实践指南,探讨复发性子宫内膜癌的综合治疗方案。