Schwannom der Nasenhaupthöhle

Schwannomas of the nasal cavity and paranasal sinuses are quite rare, with 4% occurring in this location. Most of them are benign and do not recur when totally removed by surgery. It is very important to distinguish between schwannoma and primary benign neurofibroma. Neurofibromas are lesions having the possibility for malignant transformation and recurrence. A case of schwannoma in the nasal cavity is reported, and the diagnostic and therapeutic procedures, as well as recommendations from the literature, are described. The histological and immunohistochemical features are discussed in detail to draw a distinction between schwannoma and neurofibroma. In cases of intranasal and paranasal lesions, the existence of a schwannoma must be considered. Differentiating between schwannoma and neurofibroma is important for estimating the risk of malignant transformation and recurrence.     

Ancient schwannoma of the nasal septum associated with sphenoid sinus mucocele

Schwannoma is a benign tumor arising from the sheath of myelinated nerve fibers and may occur in any part of the body. Ancient schwannoma, a variant of schwannomas, in the head and neck region is uncommon, and its occurrence in the nasal cavity and paranasal sinuses is extremely rare with only one case reported to date. Herein, we describe a rare case of sinonasal ancient schwannoma. The tumor arose from the nasal septum and extended to the sphenoid sinus. It was successfully treated by endoscopic sinus surgery, and the patient showed no evidence of recurrence 24 months postoperatively.     

Giant ethmoid neurinoma with intracranial extension

The schwannomas are tumors arising from nervous tissue. It appears very rarely in the nose and paranasal sinuses. Intra and extracraneal extension of these tumors are even more uncommon. In this paper we report a case of a esfeno-ethmoidal schwannoma with anterior skull fossa extension. We describe the CT scan and magnetic resonance imaging and the histological features. Surgical resection was carried through a craniofacial approach. Some data about diagnosis, treatment and outcome of these tumors are revised.     

Schwannomas of the paranasal sinuses. Case report and clinicopathologic analysis

Schwann's cell tumors are common neoplasms arising from the neural sheath of autonomic, cranial, or peripheral nerves. We describe a case of destructive malignant schwannoma of the right ethmoid and sphenoid sinuses. The tumor was successfully treated by surgical excision, external radiotherapy, and radon seed implants. The patient remains symptom free 3 years after therapy ended, emphasizing the previously unrecognized benefits of radiotherapy for these types of tumors. The value of endoscopy in diagnosing and following schwannomas of the nasal and paranasal sinuses is highlighted in our review of the clinicopathologic features and radiologic findings of this tumor.     

Nasal neurinoma: communication of a case and clinicopathologic analysis

The schwannomas are tumors arising from nervous tissue. It appears very rarely in the nose and paranasal sinuses. We report a case of a female whit nasal obstruction that presents a nasal neurinoma schwannoma.     

Schwannoma of maxillary sinus

Schwannoma, also known as neurilemmoma, is a solitary, encapsulated peripheral tumour of neuroectodermal derivation that originates from schwann cells of neural sheath of motor/ sensory peripheral nerves or sympathetic nerves. About one- third of all schwannomas occur in head and neck region but nose and paranasal sinuses, are rare sites. We report a case of schwannoma arising from the maxillary sinus and eroding the orbital floor. To the best of our knowledge, this is the sixth; case of schwannoma solely arising in the maxillary sinus, reported in the literature.     

Primary osteoma of the sphenoid sinus

Osteomas of the nose and paranasal sinuses are rather common benign tumors arising in the head and neck area. The sphenoid sinus is involved in various inflammatory and neoplastic conditions; however, an osteoma arising from the sphenoid sinus proper has not been reported in the available literature. This paper reviews, in detail, osteomas of the paranasal sinuses and their incidence, and a case of a sphenoid sinus osteoma is presented with radiological and pathological findings.     

Infantile hemangiopericytoma of nasal cavity

Hemangiopericytoma is an uncommon vascular tumour. Of the 26 intranasal hemangiopericytomas reported in the English literature only two paediatric cases have been noted. A benign course is more common in the nose and paranasal sinuses. A pre-operative diagnosis being not possible, definitive treatment cannot be preplanned. Wide surgical excision by a lateral rhinotomy approach is still the treatment of choice. The appropriate investigations and treatment line followed are described. A lifelong followup is mandatory.     

Inverted papillomas of the nose and the paranasal sinuses

A series of 21 patients with inverted papillomas of the nose and/or the paranasal sinuses is presented. In 19 patients the tumour arose from the lateral nasal wall or paranasal sinuses, in 2 it arose from the nasal septum. Nine patients had been previously treated by nasal polypectomy. None of the patients with recurrences after primary surgical treatment showed any evidence of a progression from benign to malignant lesions. Only 14% of the patients suffered from recurrence, and it seems likely that this is because extensive surgical extirpation was recommended as primary treatment in most cases. We feel justified in recommending early and radical surgery.     

Clinico-morphological substantiation of the selection of optimal variants of therapeutic tactics in non-epithelial tumors of the nasal cavity and paranasal sinuses

Out of 227 cases of nonepithelial tumors of the nasal cavity and paranasal sinuses, 147 patients with benign neoplasms had a good prognosis while 80 patients with malignant neoplasms had a poor prognosis. The efficacy of their therapy can be enhanced on the basis of a differential approach, measurement of tissue radiosensitivity and adequate surgical intervention.     

Endoscopic sinus surgery for benign and malignant nasal and sinus neoplasm

PURPOSE OF REVIEW: Endoscopic sinus surgery has become widely accepted as the standard of treatment for chronic inflammatory diseases of the paranasal sinuses unresponsive to medical treatment. With increased skill with endoscopic surgical technique, advanced technologies such as intraoperative imaging systems, and a better understanding of the complex anatomy of the paranasal sinuses and surrounding vital structures, many otolaryngologists have increasingly applied their expertise in endoscopic sinus surgery to the resection of nasal and sinus neoplasms. The following represents a review of the recent literature on the latest trends regarding endoscopic resection of nasal and paranasal sinus neoplasms. RECENT FINDINGS: There has been an increasing popularity in the removal of nasal and paranasal sinus neoplasms through an endoscopic approach. In the recent literature, emphasis has been on the endoscopic surgery of benign tumors, especially inverted papilloma and nasopharyngeal angiofibroma. Other benign neoplasms have also been reported, but only in small case reports. There have been a few recent reports supporting endoscopic removal of malignant neoplasms as well. However, the follow-up is too short and study groups too small to make definitive conclusions. SUMMARY: In the hand of experienced and skilled surgeons, complete endoscopic removal is attainable in most cases. Especially for the more common benign neoplasms, such as inverted papilloma and early stage angiofibroma. En bloc resection is not necessary to achieve oncologic cure. However, several factors have to be considered before selection of this surgical approach. Large tumor size, intracranial or orbital extension, and extensive frontal or infratemporal fossa involvement are relative, but not absolute limitations.     

Hemangiopericytoma like tumor — a diagnostic challenge

Haemangjopericytoma is a vascular tumour rarely seen in common practice, especially in head & neck. Hemangjopericytoma — like tumor is an even more rare entity and only 70 cases have been described arising from the nose & paranasal sinuses. The aim of this paper is to review the literature and highlight the ability of the tumor to masquerade as a less ominous, more commonly occurring benign growth of the region thereby making the diagnosis even more elusive.     

Endoscopic treatment of benign tumors of the nose and paranasal sinuses: a report of 33 cases

BACKGROUND: The endoscopic approach can be used successfully for the treatment of benign tumors such as fibroosseous and vascular lesions, pleomorphic adenoma, glioma, meningioma, and schwannoma. METHODS: Thirty-three patients diagnosed with benign tumors of the nasal cavity and paranasal sinuses and treated using an endoscopic approach were reviewed retrospectively. The endoscopic approach was simple in 28 cases and associated with an external approach in 5 cases (because of an intracranial extension of the tumor in four patients and its location at the level of the anterior wall of the frontal sinus in the last case). RESULTS: The resection of the lesions was complete in 32 patients and subtotal in one case. The mean follow-up was 28 months and only two recurrences (6%) were observed in the juvenile angiofibroma group and in the case of the fibrous dysplasia associated to aneurysmal bone cyst, respectively, 20 and 24 months postoperatively. CONCLUSION: In selected cases, endoscopic surgery can be considered an effective treatment for the resection of benign tumors involving the sinonasal tract.     

鼻腔鼻窦神经鞘瘤13例临床分析

目的 探讨鼻腔鼻窦神经鞘瘤的临床特征,以提高对该病的认识及诊疗水平。 方法 回顾性分析2012~2021年间郑州大学第一附属医院收治的13例鼻腔鼻窦神经鞘瘤患者的临床病例资料。 结果 13例患者中女10例、男3例。恶性1例,良性12例,13例均行手术治疗,1例恶性神经鞘瘤患者术后辅助放疗。术后随访4~110个月,12例良性患者均未复发,1例恶性患者死于复发。 结论 发生于鼻腔鼻窦的神经鞘瘤以良性为主,临床表现无特异性,单侧鼻塞和头痛最多见,鼻腔及筛窦为最常见发病部位。术前的影像学检查能较好显示肿瘤侵犯范围,指导手术方式。主要治疗手段为彻底手术切除,恶性者术后容易复发,需要辅助放疗。     

Endonasal approach for nasal and paranasal sinus tumor removal.

Patients with benign (53) and malignant (22) tumors of the nose and paranasal sinuses were treated for tumor removal via an endonasal approach. Patient selection was based on tumor location (centrally) rather than histology. Tumors attainable by the endonasal approach were located in the nasal cavity, the ethmoid sinus, the sphenoid sinus and the medial wall of the maxillary sinus. Endonasal microscopic techniques including endonasal orbital decompression and endonasal closure of CSF-leaks were combined with surgical navigation tools in selected cases. Surgical trauma and morbidity could be minimized without compromising radicality of tumor removal. Postoperative hospitalization was comparable to the period needed after chronic inflammatory disease. Growing experience with endonasal techniques is leading towards a safe and effective treatment option for centrally located, selected tumors of the nose and paranasal sinuses.     

Cellular schwannoma of the paranasal sinuses: initial report of a case

Cellular schwannomas are a benign variant of classic schwannomas. Their histologic appearance closely mimics that of malignant peripheral nerve-sheath tumors, which are high-grade sarcomas. In this article, we describe what to our knowledge is the first reported case of a cellular schwannoma of the paranasal sinuses and only the 33rd reported case of any schwannoma at this site. We also discuss the histology and management of cellular schwannomas and review the pertinent literature.     

Haemangiopericytoma of the nose and paranasal sinuses

The uncertain course and rarity of haemangiopericytoma in the nose and paranasal sinuses has interested both pathologists and clinicians. This tumour arises from proliferation of pericytes which invest capillary endothelium. A benign course is more common in the nose and paranasal sinuses. The first nasal haemangiopericytoma was reported by Stout in 1949. Since then only twenty cases have been reported in the literature. We present three further cases.     

Inflammatory pseudotumor of paranasal sinuses

Inflammatory pseudotumor is a rare benign lesion of unknown etiology which was first described in the lung. In head and neck the areas most commonly involved are the orbit and paranasal sinuses, but they have been also described in the larynx, pterygomaxilar space, tonsils, ears, gingiva and other periodontal tissues. We present a case of a 64 years old male who presented a three months history of right nasal obstruction. Physical examination showed a big nasal tumor arising from the nostril. CT scan shows nasal fossa mass with a normal paranasal sinuses. Histology made the diagnosis of an inflammatory pseudotumor. The lesion was surgically removed trough a midface degloving approach. The patient has no signs of recurrence two years after surgery. Data about diagnosis, treatment and outcome of inflammatory pseudotumors is revised also in this paper.     

Middle turbinate osteoma

Osteoma is the most common benign tumor of the paranasal sinuses. Turbinate osteomas are very rare and only four middle turbinate, one superior turbinate and one inferior turbinate osteoma cases have been reported. We present a rare case of osteoma of the left middle turbinate in a patient presented with unilateral nasal obstruction and epiphora that was removed endoscopically, and conduct a literature review on turbinate osteomas arising from different turbinates, their symptoms and management.