Nutrition and HIV infection

Infection by the human immunodeficiency virus (HIV) is characterized by progressive destruction of the immune system, which leads to recurrent opportunistic infections and malignancies, progressive debilitation and death. Malnutrition is one major complication of HIV infection and is recognized as a significant prognostic factor in advanced disease. Malnutrition is multifactorial and poorly treated during the course of HIV. Even if a standardized approach to the management of active weight loss has not been well established, early nutritional intervention is important in HIV infected patients to maximize gain of lean body mass. From early in the era of highly active antiretroviral therapy (HAART), an initial decreased incidence of malnutrition was noted only in western countries while a variety of changes in the distribution of body fat and associated metabolic abnormalities have been recognized under the banner of lipodystrophy.     

Nutrition assessment in long-term care.

Assessment of nutrition status is necessary in long-term care settings for both optimal patient care and to meet regulatory standards. Careful nutrition assessment leads to development of an individual plan of care to optimize nutrition status. Although the Minimum Data Set is mandated as the nutrition assessment tool in long-term care settings, published studies show that the use of the Minimum Data Set to assess nutrition status is problematic. Two types of nutrition assessment instruments have been developed. The first type aims to identify those at risk for malnutrition but is not used to diagnose clinical malnutrition, whereas the second type has been designed to diagnose malnutrition. A number of commonly used nutrition assessment tools have not been validated in long-term care populations. This review focuses on the available tools used in the long-term care setting and provides an overview of their characteristics and performance measures.     

Nutritional assessment of drug addicts. Relation with HIV infection in early stages

OBJECTIVE: To assess the nutritional status of drug addicts without acute organic pathology, in order to determine the prevalence of malnutrition and to discern if early HIV infection is associated with a poor nutritional status in this group of patients. DESIGN: Prospective study. SETTING: Detoxication unit of a university hospital. PATIENTS: 140 drug addicts without acute organic pathology. 31 patients were HIV+. No one fulfilled the definition of AIDS. RESULTS: We found that drug addicts were undernourished: 92.4% weighed under the mean populational weight and 55.7% had a weight loss above 5%. The distribution of mid upper arm circumference (MUAC), triceps skinfold (TSF) and mid arm muscle area (MAMA) was lower than a reference normal population. Food intakes were poor; 66.4% of our patients complained of anorexia on admission. The mean caloric intake was 978 +/- 89 kcal/day in females and 1265 +/- 64 kcal/day in males. The mean protein intakes were 39.3 +/- 3.3 g/day in females (0.76 +/- 0.07 g/kg/day) and 49.7 +/- 2.7 g/day in males (0.77 +/- 0.04 g/kg/day). When we compared nutritional parameters between HIV+ and HIV- patients we found no differences. CONCLUSIONS: Nutritional impairment in drugs abusers with early stages of HIV infection should be attributed to drug abuse rather than to HIV infection.     

Nutrition and HIV in the international setting.

HIV infection has become increasingly prevalent globally, with more than 40 million infected individuals worldwide, the majority of whom live in the resource-limited world, especially sub-Saharan Africa and Asia. There are nutritional and metabolic issues that significantly impact morbidity and mortality in HIV-infected populations. In addition, malnutrition has been associated with an increased risk of transmission of HIV from infected mothers to infants, and malnutrition may further compromise HIV-infected individuals who have tuberculosis or persistent diarrheal disease. The introduction of highly active antiretroviral therapy will have a significant impact on the mortality of HIV, but will not completely alleviate the malnutrition associated with HIV infection in the global setting.     

Primary care physicians' assessment and prevention of HIV infection

The degree and depth to which primary care physicians counsel patients at risk for human immunodeficiency virus (HIV) infection is a major concern. To determine which factors influence whether physicians counsel patients at risk for HIV, primary care physicians's clinical experience, knowledge, attitudes, and preventive counseling advice in hypothetical case scenarios were assessed. Ninety-nine adult primary care physicians in the Washington, D.C., metropolitan area were interviewed by telephone from May through November 1987. Ninety-one physicians had tested or referred patients for HIV antibody tests. However, 58% could not name the ELISA or Western blot as the tests. The most frequent HIV prevention recommendations were using condoms (67.7%), abstaining from sexual activity (36.4%), getting tested for HIV (30.3%), and safe sex (23.2%). Naming the HIV antibody tests was the most significant predictor of preventive counseling advice; other significant predictors included physicians' personal comfort with counseling homosexual patients and various physician practice and demographic characteristics. Previous studies showed that homophobia was the main inhibitor of effective AIDS counseling. These results suggest that physicians' lack of knowledge and general discomfort in counseling patients about sexual risk factors, rather than homophobia alone, are important barriers to preventive counseling about HIV infection.     

Quality of life assessment and HIV infection: A review

In the last few years, survival of patients infected with human immunodeficiency virus (HIV) has been improved because of a decreased incidence of some opportunistic complications attributable to prophylactic treatments and antiretroviral drugs. The impact of these agents should also be reflected in the quality of life (QoL) of patients. We have reviewed this topic with an emphasis on different types of measurements such as Q-TWIST, MOS and the Spitzer score which seem to be most appropriate for this patient population. We do not think that a special type of assessment should be designed for HIV-infected persons. It would be less time-consuming to improve already existing validated scores focusing on HIV infection. QoL in intravenous drug users with HIV should be evaluated more often.     

HIV infection in an Ethiopian prison.

HIV-1 antibody was detected in 6.0 percent of prisoners in an Ethiopian prison. HIV-1 seropositivity was strongly associated with positive VDRL status (RR = 3.7) and recent admission to prison (RR = 3.5). Seropositive prisoners were more likely to have prostitute contacts. No correlation was found between seropositivity and number of sexual contacts, long-term sex partners, or dental extractions. HIV-1 infection in this area may be of recent origin and the high prevalence may reflect rates in the surrounding community.     

营养评估在临床护理工作中的应用

南丁格尔[1] 指出 ,护士通过重视营养摄入而在伤员的伤愈过程中发挥积极作用。现代营养护理范畴也从饮食指导扩展到 (ＥＮ )、(ＰＮ)等代谢支持的实施、监测。作为一种护理行为 ,营养护理也应纳入护理程序的框架之中。因而 ,营养评估是科学地进行营养护理的首要步骤。1　营养评估的作用自 70年代发现营养缺乏病占住院病人总数的一半以上 ,而且主要是蛋白 热能缺乏 (ｐｒｏｔｅｉｎ ｃａｌｏｒｉｅｍａｌｎｕｔｒｉｔｉｏｎ ,ＰＣＭ )以来 ,研究与发展了医院病人临床营养评估方法。医院建立了营养支持服务小组 ,共同实施ＰＮ、ＥＮ。使营养…     

Nutrition assessment in the elderly

The prevalence of malnutrition, which is relatively low in free-living elderly persons (5-10%), is considerably higher (30-60%) in hospitalized or institutionalized elderly persons. As a result, nutritional assessment should be part of routine clinical practice in elderly patients who are frail, sick or hospitalized. A comprehensive screening tool for assessment of nutritional status is needed that is clinically relevant and cost-effective to perform. A number of simple and rapid tests for detecting or diagnosing malnutrition in the elderly have recently been developed. If malnutrition is suggested by such screening tests, then they should be supplemented by conventional nutritional assessment before treatment is planned.     

HIV infection among women in prison: an assessment of risk factors using a nonnominal methodology.

The relative contributions of needle use practices and sexual behaviors to human immunodeficiency virus (HIV) antibody seropositivity among 394 women incarcerated in Quebec were determined by risk factor assessment and serology with a nonnominal methodology. HIV positivity was found in 6.9% (95% confidence interval [CI] = 4.6, 9.9) of all participants and in 13% (95% CI = 8.6, 18.6) of women with a history of injection drug use. HIV seropositivity among women with a history of injection drug use was predicted by sexual or needle contact with a seropositive person, self-reported genital herpes, and having had a regular sexual partner who injected drugs, but it was not predicted by prostitution. Nonnominal testing is an ethical alternative to mandatory and anonymous unlinked testing among correctional populations.