电针结合耳针治疗急性脊髓损伤的临床研究

目的评估电针结合耳针治疗急性脊髓损伤的疗效和安全性。方法我院1999年1月～2004年5月期间急性脊髓损伤美国脊髓损伤学会（ASIA）损伤分级A级和B级患者56例，随机分为针灸治疗组和对照组。针灸治疗组采用双侧后溪和申脉点电针，与脊髓相关耳穴的耳针，同时配合康复治疗。对照组仅仅采用康复治疗。分别记录入院时、出院时及出院后1年ASIA损伤分级及ASIA神经（运动、感觉）功能状况评分、独立性功能评定（FIM）及不良反应。结果在神经（感觉和运动）功能和FIM评分方面针灸治疗组优于对照组（P〈0．05），无明显不良反应。结论早期采用电针结合耳针治疗急性脊髓损伤有较好的疗效和安全性。     

Early rehabilitation effect for traumatic spinal cord injury

OBJECTIVE: To determine the natural course of traumatic spinal cord injury (SCI) and the effect of early rehabilitation on it. DESIGN: A retrospective, multicenter study. SETTING: Sixteen Rosai hospitals and 1 medical school. PARTICIPANTS: One hundred twenty-three SCI patients (104 men, 19 women; mean age, 48.8 +/- 17.7yr) enrolled. INTERVENTIONS: Dividing the subjects into an early rehabilitation group and a delayed group; differences were ensured by international classification of SCI. MAIN OUTCOME MEASURES: Using the American Spinal Injury Association (ASIA) classifications, the motor recovery rate (MRR) was defined as (ASIA motor score at discharge - ASIA motor score at admission)/(100 - ASIA motor score at admission). The regression lines for FIM instrument score and ASIA motor score were determined for 6 subgroups (early or delayed tetraplegia, central cord injury, paraplegia) by the MRR staging. The regression lines for physical or cognitive FIM score and ASIA motor score were also determined for 6 subgroups. RESULTS: Three stages were obtained: acute stage: 2 weeks postinjury; recovery stage: 2 weeks to 6 months postinjury; and chronic stage: more than 6 months postinjury. Regression lines showed that rehabilitation improved physical functional independence for ASIA motor score, especially in the early rehabilitation subgroups. There was no correlation between cognitive FIM score and ASIA motor score in 6 subgroups. CONCLUSION: Early SCI rehabilitation contributes to good physical activities of daily living for motor function.     

Outcomes of early surgical management versus late or no surgical intervention after acute spinal cord injury

OBJECTIVE: To compare neurologic, medical, and functional outcomes of patients with acute spinal cord injury (SCI) undergoing early (<24 h and 24-72 h) and late (>72 h) surgical spine intervention versus those treated nonsurgically. DESIGN: Retrospective case series comparing outcomes by surgical and nonsurgical groups during acute care, rehabilitation, and at 1-year follow-up. SETTING: Multicenter National Spinal Cord Injury Database. PARTICIPANTS: Consecutive patients with acute, nonpenetrating, traumatic SCI from 1995 to 2000, admitted in the first 24 hours after injury. Surgical spinal intervention was likely secondary to nature of injury and the need for spinal stabilization. Interventions Not applicable. MAIN OUTCOME MEASURES: Changes in neurologic outcomes (motor and sensory levels, motor index score, American Spinal Injury Association [ASIA] Impairment Scale [AIS]), medical complications (pneumonia and atelectasis, deep vein thrombosis and pulmonary embolism, pressure ulcers, autonomic dysreflexia, rehospitalization), and functional outcomes (acute and rehabilitation length of stay [LOS], hospital charges, FIM instrument score, FIM motor efficiency scores). RESULTS: Subjects in the early surgery group were more likely ( P <.05) to be women, have paraplegia, and have SCI caused by motor vehicle collisions. The nonsurgical group was more likely ( P <.05) to have an older mean age and more incomplete injuries. ASIA motor index improvements (from admission to 1-y follow-up) were more likely ( P <.05) in the nonsurgical groups, as compared with the surgical groups. Those with late surgery had significantly ( P <.05) increased acute care and total LOS and hospital charges along with higher incidence of pneumonia and atelectasis. No differences between groups were found for changes in neurologic levels, AIS grade, or FIM motor efficiency. CONCLUSIONS: ASIA motor index improvements were noted in the nonsurgery group, though likely related to increased incompleteness of injuries within this group. Early versus late spinal surgery was associated with shorter LOS and reduced pulmonary complications, however, no differences in neurologic or functional improvements were noted between early or late surgical groups.     

Neoplastic vs. traumatic spinal cord injury: an inpatient rehabilitation comparison

OBJECTIVE: To compare demographics, injury characteristics, and functional outcomes of patients with neoplastic spinal cord compression with those with traumatic spinal cord injuries. DESIGN: A prospective 5-yr comparison was undertaken comparing 34 patients with neoplastic spinal cord compression with 159 patients with traumatic spinal cord injury. RESULTS: Patients with neoplastic spinal cord compression were significantly older, more often female, and unemployed than patients with traumatic spinal cord injury. Neoplastic spinal cord compression presented more often with paraplegia involving the thoracic spine, and injuries were more often incomplete compared with traumatic spinal cord injury. Patients with neoplastic spinal cord compression had a significantly shorter rehabilitation length of stay compared with those with traumatic spinal cord injury. The neoplastic group had significantly lower FIM change scores. Both groups had similar FIM efficiencies and discharge to home rates. CONCLUSIONS: Patients with neoplastic spinal cord compression have different demographic and injury characteristics but can achieve comparable rates of functional gains as their traumatic spinal cord injury counterparts. Although patients with traumatic injuries achieve greater functional improvement, patients with neoplasms have a shorter rehabilitation length of stay and comparable FIM efficiencies and home discharge rates.     

基于3D高分辨肛门直肠测压研究针刺对脊髓损伤神经源性肠道的疗效

目的:利用3D高分辨肛门直肠测压(3DHR-ARM)观察针刺联合常规康复治疗对脊髓损伤后神经源性肠道(NBD)的疗效。方法:选取外伤致脊髓损伤术后神经源性肠道患者40例,随机分为对照组与研究组各20例,对照组予常规康复治疗,进行肠道功能训练,研究组在此基础上再配合针刺治疗,应用3D HR-ARM、美国脊柱损伤协会(ASIA)评分、神经源性肠道功能障碍(NBD)评分、Barthel指数(BI)对患者进行评定。结果:治疗后,2组肛门括约肌收缩压、直肠压力、直肠肛管压力差、Barthel指数(BI)评分、美国脊柱损伤协会(ASIA)评分较治疗前均明显提高(均P<0.05),便意阈值、神经源性肠道(NBD)评分较治疗前均明显下降(均P<0.05),静息压、高压带长度治疗前后差异无统计学意义,其中,研究组肛门括约肌收缩压、直肠压力、直肠肛管压力差、便意阈值较对照组差异均有统计学意义(均P<0.05)。Pearson相关性分析结果显示:肛门括约肌收缩压、BI评分与ASIA评分成正相关(P<0.05),便意阈值、NBD评分与ASIA评分成负相关(P<0.05)。结论:针刺联合常规康复治疗能更有效地改善脊髓损伤后神经源性肠道功能,3D高分辨肛门直肠测压结果与量表评定具相关性,有望成为神经源性肠道疗效的客观评价指标。     

神经肌肉电刺激辅助治疗脊髓损伤神经源性膀胱的临床探析

目的：探讨神经肌肉电刺激辅助治疗脊髓损伤神经源性膀胱（NB）的临床疗效。方法将72例脊髓损伤NB患者随机分为电刺激组和常规组各36例。常规组仅接受康复治疗结合膀胱训练等常规治疗,观察组在常规组治疗基础上辅助接受神经肌肉电刺激治疗。比较两组治疗后的总有效率、24 h排尿次数、每次排尿量、残余尿量以及神经功能评分（ASIA评分）。结果治疗后观察组的总有效率、24 h 排尿次数、每次排尿量、残余尿量方面均优于常规组[分别为97.2％ vs.55.6％,（5.1±1.2）次vs （8.3±2.2）次,（189.9±11.4）ml vs （145.3±10.8）ml,（90.2±2.4） ml vs （110.1±3.3）ml,均为P＜0.05]。两组的ASIA评分比较差异无统计学意义（P＞0.05）。两组均无发生明显不良反应。结论神经肌肉电刺激辅助治疗能明显改善脊髓损伤NB患者临床症状,有利于患者康复,是一种治疗NB的好的辅助疗法。     

Late neurologic recovery after traumatic spinal cord injury

OBJECTIVE: To present Model Spinal Cord Injury System (MSCIS) data on late neurologic recovery after 1 year after spinal cord injury (SCI). DESIGN: Longitudinal study of neurologic status as determined by annual evaluations at 1 and 5 years postinjury. SETTING: MSCIS centers contributing data on people with traumatic SCI to the National Spinal Cord Injury Statistical Center database. PARTICIPANTS: People with traumatic SCI (N=987) admitted to an MSCIS between 1988 and 1997 with 1- and 5-year follow-up examinations. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: American Spinal Injury Association (ASIA) Impairment Scale (AIS) classification, motor index scores (MIS), motor level, and neurologic level of injury (NLI), measured and compared for changes over time. RESULTS: The majority of subjects (94.4%) who had a neurologically complete injury at 1 year remained complete at 5 years postinjury, with 3.5% improving to AIS grade B, and up to 1.05% each improving to AIS grades C and D. There was a statistically significant change noted for MIS. There were no significant changes for the motor level and NLI over 4 years; however, approximately 20% of subjects improved their motor level and NLI. People with complete and incomplete injuries had similar improvements in motor level, but subjects with an incomplete injury had a greater chance of improvement in NLI and MIS. CONCLUSIONS: There was a small degree of neurologic recovery (between 1 and 5 y postinjury) after a traumatic SCI. Late conversion, between 1 and 5 years, from a neurologically complete to an incomplete injury occurred in 5.6% of cases, but in only up to 2.1% was there a conversion from motor complete to motor incomplete status. Limitations of this study included changes in the ASIA classification during the study and in the intra- and interrater reliability typically seen in longitudinal studies of the ASIA standards. Functional changes were not studied. Knowledge of the degree of late recovery may help in analyzing newer interventions to enhance recovery.     

早期高压氧治疗对急性创伤性脊髓损伤患者疗效的影响

【目的】探讨早期高压氧（HBO）治疗对急性创伤性脊髓损伤（SCI）患者疗效的影响。【方法】将86例急性脊髓损伤患者随机分为早期HBO组（A组）28例、晚期HBO组（B组）32例及对照组（C组）26例。C组采取常规处理（包括脱水剂、皮质激素、神经营养药物、胃黏膜保护药物、康复训练、针灸以及对症支持治疗等）,A组患者在此基础上于SCI发生12h以内辅以HBO治疗,B组患者在此基础上于SCI发生3d以后辅以HB0治疗,于治疗前及治疗3个月后分别采用美国脊髓损伤协会（ASIA）评分、改良Barthel指数（MBI）及功能独立性评定量表（FIM）对患者进行测评。【结果】三组患者ASIA感觉、运动功能评分及MBI、FIM分值均较治疗前显著改善（P〈0．01）,组间治疗后ASIA感觉功能评分比较有显著差异（P〈0．01）,治疗后ASIA运动功能评分比较有显著差异（P〈0．05）。治疗后各组间MBI及FIM分值比较有显著性差异（P〈0．01）。【结论】HBO能显著改善急性SCI患者脊髓功能、日常生活活动能力及独立能力,且越早开始治疗效果越好。     

纳洛酮治疗非外伤性急性脊髓损伤的疗效观察

目的探讨纳洛酮对急性非外伤性脊髓损伤的治疗作用。方法将40例急性非外伤性脊髓损伤患者随机分成2组,分别接受激素,激素加纳洛酮治疗,比较治疗前后神经缺失功能。结果治疗前两组神经功能评分无显著性差异,治疗14d、1个月后神经功能评分均有改善,观察组有效率为75%,显效率为50%;对照组有效率为65%,显效率为40%,两组比较有显著性差异。结论纳洛酮可作为治疗急性非特异性脊髓损伤的常规治疗方法。     

高压氧治疗外伤性脊髓损伤39例临床护理

目的:探讨高压氧在治疗外伤性脊髓损伤患者的效果及护理方法.方法:将78例脊髓损伤患者随机分为对照组和治疗组各39例,伤后2周内两组均行减压、脊柱内固定术,对照组使用常规治疗,治疗组在此基础上配合高压氧治疗.结果:治疗组显效率为71.8%,对照组为25.6%,两组比较差异有统计学意义(P<0.05);两组在感觉平面及运动平面得分比较差异有统计学意义(P<0.05).结论:高压氧综合治疗脊髓损伤可以有效促进患者脊髓功能恢复,降低致残率,改善患者预后.     

Sex-related differences of rehabilitation outcomes of spinal cord lesion patients

OBJECTIVES: To evaluate sex-related differences of spinal cord lesion patients. PATIENTS: Two hundred and eighty-one patients were included with evaluation of: lesion to admission time, aetiology, lesion level, associated injury, medical complications and surgical intervention, length of stay, American Spinal Injury Association (ASIA) impairment and motor scores. MAIN OUTCOME MEASURES: ASIA impairment grade and ASIA motor scores; Barthel Index, Rivermead Mobility Index and Walking Index for Spinal Cord Injury. RESULTS: In the entire group female patients had a lower frequency of traumatic lesions, a lower frequency of complications at admission and a higher frequency of incomplete lesions (ASIA impairment C). In the matching cohorts comparison female patients showed the same neurological and functional recovery as male patients. CONCLUSION: Gender does not seems to influence spinal cord rehabilitation outcomes despite the fact that men and women showed significant epidemiological differences. Further studies are needed to evaluate some aspects such as long-term bladder management and complications.     

Predictors of dysphagia after spinal cord injury.

OBJECTIVE: To quantify the incidence of swallowing deficits (dysphagia) and to identify factors that predict risk for dysphagia in the rehabilitation setting following acute traumatic spinal cord injury. DESIGN: Retrospective case-control study. SETTING: Freestanding rehabilitation hospital. PATIENTS: Data were collected on 187 patients with acute traumatic spinal cord injury admitted for rehabilitation over a 4-year period who underwent a swallowing screen, in which 42 underwent a videofluoroscopic swallowing study (VFSS). MAIN OUTCOME MEASURES: VFSS was performed on patients with suspected swallowing problems. Possible antecedents of dysphagia were recorded from the medical record including previous history of spine surgery, surgical approach and technique, tracheostomy and ventilator status, neurologic level of injury, ASIA Impairment Classification, orthosis, etiology of injury, age, and gender. RESULTS: On admission to rehabilitation 22.5% (n = 42) of spinal cord injury patients had symptoms suggesting dysphagia. In 73.8% (n = 31) of these cases, testing confirmed dysphagia (aspiration or requiring a modified diet), while VFSS ruled out dysphagia in 26.2% (n = 11) cases. Logistic regression and other analyses revealed three significant predictors of risk for dysphagia: age (p < .028), tracheostomy and mechanical ventilation (p < .001), and spinal surgery via an anterior cervical approach (p < .016). Other variables analyzed had no relation or at best a slight relation to dysphagia. Tracheostomy at admission was the strongest predictor of dysphagia. The combination of tracheostomy at rehabilitation admission and anterior surgical approach had an extremely high rate of dysphagia (48%). CONCLUSION: Swallowing abnormalities are present in a significant percentage of patients presenting to rehabilitation with acute traumatic cervical spinal cord injury. Patients with a tracheostomy appear to have a substantially increased risk of development of dysphagia, although other factors are also relevant. Risk of dysphagia should be evaluated to decrease the potential for morbidity related to swallowing abnormalities.     

Biostep运动训练系统在腰髓完全性损伤患者康复训练中的应用

目的:研究在常规康复治疗的基础上,应用Biostep运动康复训练系统对腰髓完全性损伤患者进行运动训练的意义。方法:46例腰髓完全性损伤患者,随机分为Biostep训练组(治疗组)和常规康复训练组(对照组),每组各23例。两组患者均接受常规综合康复治疗,治疗组在此基础上,增加Biostep运动训练治疗。在治疗前和治疗2个月后对两组患者进行ASIA下肢运动评分、脊髓损伤步行指数Ⅱ(WISCIⅡ)、10m步行测试(10MWT)及功能独立性评定(FIM)。结果:两组治疗前后组内比较,治疗后ASIA运动评分、WISCIⅡ、10MWT和FIM评分均有明显提高,差异有显著性意义(P<0.05)。治疗组在ASIA下肢运动评分、WISCIⅡ和10MWT方面改善均优于对照组,差异有显著性意义(P<0.05)。结论:常规康复治疗辅以Biostep康复训练系统进行训练,对提高腰髓完全性损伤患者步行功能有重要意义。     

非创伤性脊髓损伤的临床特点

目的探讨非创伤性脊髓损伤患者的人口学特征、病因学分布以及神经功能预后。方法对44 例非创伤性因素造成的脊髓损伤患者的临床资料进行回顾性分析。结果患者均获得3 个月以上随访,平均随访时间13.3 个月(3~23 个月)。其中男性27 例(61.3%),女性17 例(38.7%);平均年龄39.85 岁(3.5~78 岁)。病因包括脊髓炎16 例(36%),脊柱肿瘤8 例(18.1%),椎管内肿瘤7例(15.9%),脊髓血管畸形6 例(13.6%),非创伤性椎间盘突出3 例(6.8%,包括颈椎间盘突出致四肢瘫1 例,腰椎间盘突出致马尾综合征2 例),非脊柱手术造成的医源性脊髓缺血2 例(4.5%),肝性脊髓病2 例(4.5%)。入院时神经损伤情况：颈段脊髓损伤9 例(20.4%),胸段损伤30 例(68.1%),圆锥综合征2 例(4.5%),马尾综合征3 例(6.8%)。AISA 残损分级：A级14 例(31.8%),B级6 例(13.6%),C级13 例(29.5%),D级11 例(25%)。最终随访时,34%患者出现至少1 个等级的神经功能恢复。结论非创伤性脊髓损伤是造成脊髓损伤的重要原因。因具有特殊的病因学特点,此组病例在人口学特征以及临床特点上与创伤性脊髓损伤患者有较大区别。     

Clinical trial of electrical acupuncture on hemiplegic stroke patients

To assess the efficacy of electrical acupuncture in the rehabilitation of patients with hemiplegia in stroke, we randomized 128 patients within 2 wk of stroke onset to receive either comprehensive rehabilitation plus electrical acupuncture (n = 59) or comprehensive rehabilitation only (n = 59). Electrical acupuncture was administered by electrical stimulation of acupuncture points through adhesive surface electrodes five times per week. Neurological status (Brunnstrom's stage) and the Chinese version of the Functional Independence Measure were assessed before treatment and at discharge. Patients treated with electrical acupuncture had a shorter duration of hospital stay for rehabilitation and better neurological and functional outcomes than the control group had, with a significant difference in scores for self-care and locomotion (P = 0.02). This result did not postulate the previous study that acupuncture therapy for stroke patients should depend on needle manual and "de qi" response. We suggest that electrical acupuncture through adhesive surface electrodes in conjunction with current optimal rehabilitation programs is a convenient and effective therapy for stroke patients.     

外伤性脊髓萎缩(1例报告及文献复习)

目的探讨外伤性脊髓萎缩的特征和治疗方法。方法系统观察１例外伤性脊髓萎缩的临床过程和影像改变，复习近年的有关文献。结果外伤性脊髓萎缩是一种少见的临床现象，ＭＲＩ上脊髓缩小部分从矢状径或横径测量为正常的１／４，即可诊断为脊髓萎缩。治疗上没有好的手段。结论ＭＲＩ能确诊外伤性脊髓萎缩，采用综合方法进行治疗。     

Clinical presentations, medical complications, and functional outcomes of individuals with gunshot wound-induced spinal cord injury

Gunshot wounds are currently the second leading cause of spinal cord injury in the United States, and coexisting injuries or complications accompanying penetrating wounds often increase patient morbidity. A review of 217 traumatic spinal cord injury rehabilitation admissions to a tertiary care hospital during a 5-yr period revealed 49 individuals (23%) with gunshot wound-induced spinal cord injury. A single bullet entry site was seen in 54%, whereas 17% had greater than 3 sites of entry. Common (>25%) sites of bullet entry included the back, abdomen, neck, and chest. Common gunshot wound-related medical complications included pain (54%), infections (40%), pneumothorax (24%), nonspinal fractures (22%), colonic perforation (17%), cerebrospinal fluid leak (10%), and retroperitoneal hematoma (10%). When compared with nonviolence-related traumatic spinal cord injury (motor vehicle accidents and falls), patients with gunshot wound-induced spinal cord injury were significantly more frequently (P < 0.01) younger, non-Caucasian, unmarried, and unemployed. Injury characteristics revealed significantly (P < 0.01) more paraplegia and complete spinal cord injury within the gunshot wound-induced spinal cord injury group. Gunshot wound-induced spinal cord injury and nonviolent traumatic spinal cord injury groups had similar lengths of stay, Functional Independence Measure scores, and discharge to home rates. This article adds to the growing body of literature examining clinical, medical, and functional outcome characteristics of individuals with spinal cord injury secondary to violence-related cause.     

A multicenter investigation of age-related differences in lengths of stay, hospitalization charges, and outcomes for a matched tetraplegia sample.

OBJECTIVE: To examine the effects of age at injury on lengths of stay, treatment costs, and outcomes using a matched sample of tetraplegic spinal cord injury (SCI) patients. DESIGN: Differences were examined by separating the sample into three age categories (18 to 34, 35 to 64, and 65+ years old) matched for American Spinal Injury Association (ASIA) Motor Impairment Classification and level of neurologic preservation bilaterally. Analysis of variance was used to examine age group differences for lengths of stay, medical expenses, and functional outcome. SETTING: Sixteen medical centers in the federally sponsored Spinal Cord Injury Model Systems Project. PARTICIPANTS: Three hundred seventy-five adult patients with tetraplegic SCI admitted between 1988 and 1996 were assessed at acute care admission, inpatient rehabilitation admission, and inpatient rehabilitation discharge. MAIN OUTCOME MEASURES: ASIA Motor Index and Functional Independence Measure (FIM) admission, discharge, and efficiency scores; acute care and rehabilitation lengths of stay and medical care charges; and discharge disposition. RESULTS: Analyses revealed equivalent lengths of stay and charges for all age groups. There were no age-related differences in ASIA and FIM Motor scores at acute care and inpatient rehabilitation admission. Younger patients' scores on the FIM Motor subscale improved significantly more than did middle and older patients'. The two younger groups of patients had a more significant improvement than did older patients, as indicated by ASIA Motor Index scores. When taking lengths of stay into account, the FIM motor scores of the youngest group of patients improved more quickly than those of the two older groups. Furthermore, the younger and middle age groups demonstrated greater treatment efficiency than the older patient group based on ASIA Motor Index score ratios. Younger patients were least likely to be discharged to institutional settings. CONCLUSIONS: Along with neurologic and functional status, age should be considered when formulating treatment plans and prognostic statements. For older patients, alternative rehabilitation settings with lower-intensity treatment and lower charges may prove to be a more efficacious use of resources.     

Functional improvement after pediatric spinal cord injury

OBJECTIVE: To describe the functional gain (FGain) with pediatric spinal cord injury inpatient rehabilitation and to identify the relationship of various factors to FGain in pediatric spinal cord injury inpatient rehabilitation. DESIGN: Retrospective chart review of a series of 91 children with spinal cord injury admitted from 1993 to 1998 in a freestanding rehabilitation hospital. Admission and discharge functional status were assessed with the Pediatric Functional Independence Measure (WeeFIM) instrument for children 7 yr. The outcome measure is the FGain (difference between the discharge and admission functional status). RESULTS: Significant gains in functional status were observed in all patients. FGain was not significantly related to age, sex, length of inpatient rehabilitation, pathogenesis, or completeness or neurologic level of injury. However, there was a trend for higher FGain for patients with incomplete spinal cord injury and traumatic spinal cord injury. CONCLUSIONS: Functional improvement occurs with pediatric spinal cord injury inpatient rehabilitation. There is a trend for higher FGain in patients with less severe injury and traumatic injury. The lack of relationship between FGain and length of inpatient rehabilitation suggests that a variety of other factors influence the relationship between FGain and length of inpatient rehabilitation.     

电针刺激穴位的脊髓fMRI初步研究

目的检测电针刺激合谷穴和曲池穴的脊髓fMRI的可行性。方法 8名健康志愿者,电针同时刺激右手合谷穴和右肘曲池穴,采用组块设计方法,使用SPM2软件得到功能激活的t检验图,在矢状位上分析脊柱不同区的激活总像素数和最大强度值,在横断位上观察激活区的位置,并对比不同刺激时间对激活分布和信号强度的影响。结果 8名志愿者脊髓中均存在激活,矢状面上激活点分布在脊柱C2～T1段,但主要集中在脊柱C2、C4、C5和C6段。横断面上主要激活区域位于同侧,尤其是在脊髓的后角及前角（功能区）,同时发现对侧后角有少量显著激活区。与刺激5次组相比,刺激3次组的最大激活信号强度较高,且伪激活数较少。结论使用电针刺激合谷穴和曲池穴,通过脊髓磁共振功能成像技术可观测到脊髓的功能激活区,而且激活分布具有一定特征性。