Modified external needle drainage procedure for rhegmatogenous retinal detachment

PURPOSE: To describe the results of a modified external needle subretinal fluid drainage technique to treat eyes with a rhegmatogenous retinal detachment. METHODS: One hundred eighty-seven consecutive patients with a rhegmatogenous retinal detachment who underwent scleral buckle and modified external needle drainage at Duke Eye Center or Vistar Eye Associates were included in this study. Subretinal fluid was drained by a technique whereby the intraocular pressure was raised to a supranormal level by tightening an encircling scleral buckle and then the subretinal space was entered by a needle introduced externally while the retina was directly viewed with an indirect ophthalmoscope. Subretinal fluid drainage success rate, one-operation reattachment rate, final retinal reattachment rate, intraoperative and postoperative complication rates, and final visual acuity were the main outcome measures. RESULTS: Subretinal fluid was successfully drained in all eyes. The one-operation reattachment rate was 91%, and the final reattachment rate was 98%. Intraoperatively, 15% of eyes required corneal debridement to obtain an adequate view for safe subretinal fluid drainage. Subretinal hemorrhage of no more than one clock hour occurred in 4.2% of eyes. A total of 2.6% of eyes developed an epiretinal membrane postoperatively that required a vitrectomy to improve the visual acuity. The postoperative visual acuity, 0.54 by logMAR (20/69 by Snellen), was significantly better than the preoperative visual acuity, 1.1 logMAR (20/250 by Snellen) (P < 0.0001). CONCLUSIONS: The modified external needle drainage technique is a flexible, effective method to drain subretinal fluid in eyes with a rhegmatogenous retinal detachment. The retinal reattachment rate and complication rate compare favorably to alternative subretinal fluid drainage techniques.     

Modified external needle drainage of subretinal fluid in the management of rhegmatogenous retinal detachment using a "guarded needle" approach

External needle drainage of subretinal fluid is a useful technique to assist with retinal detachment surgery. This technique provides the ability to directly visualize the removal of subretinal fluid in a controlled manner. The major difficulty in learning this technique is the potential for overpenetration with the needle. Using a "guarded needle" approach can reduce this risk and increase the adoption of this useful method.     

脉络膜脱离孔源性视网膜脱离术中不放液观察

目的 观察视网膜裂孔冷凝，巩膜环扎外加压手术不放液治疗脉络膜脱离型孔源性视网膜脱离的疗效。方法 对28眼脉络膜脱离型孔源性视网膜脱离进行裂孔冷凝，巩膜环扎，外加压，术中不引流视网膜下液，对其治疗结果进行分析。结果 28眼中一次成功25眼，视网膜下液在1～2天吸收为13眼，3天～1周内吸收为12眼，术后均有不同程度的视力提高。结论 在成功封闭裂孔后，脉脱型孔源性视网膜脱离视网膜下液可自行吸收，手术成功率高，可有效减少放液所带来的并发症。     

Shifting subretinal fluid in rhegmatogenous retinal detachment.

In a consecutive series of 470 cases of rhegmatogenous retinal detachment 25 (5%) were found to have shifting subretinal fluid (SRF) at the preoperative examination. The study showed that the association between SRF and rhegmatogenous retinal detachment is unusual but not rare. Shifting SRF was most often associated with aphakic and longstanding retinal detachment, and found in cases in which the retinal holes were small.     

基质金属蛋白酶在孔源性视网膜脱离视网膜下液的定量研究

目的 研究孔源性视网膜脱离(RRD)视网膜下液(SRF)基质金属蛋白酶(MMPs)的表达，探讨MMPs与增生性玻璃体视网膜病变(PVR)的关系。方法 采用明胶酶谱分析法定量检测88例RRD患者的SRFMMP-2和MMP-9的活性水平，PVR A组21例，PVRB组37例，PVR C组30例，其中包括伴有脉络膜脱离RRD8例，术后随访PVR复发11例。结果 88例RRD患者的SRF均有MMP-2活性水平升高，33例有MMP-9的表达，8例RRD伴有脉络膜脱离，有6例(75％)MMP-9活性水平升高，术后PVR复发11例SRF均有MMP-9活性水平升高。结论RRD患者的SRF有MMP-2和MMP-9的表达，MMP-9活性水平升高可能与PVR的发生有关，可能成为预测术后PVR复发的指标之一。     

不放液的节段性外垫压术与放液的巩膜环扎加压术的疗效比较

目的探讨不放液的节段性外垫压手术与放液的巩膜环扎加压术治疗孔源性视网膜脱离(RRD)的疗效,并对两种术式疗效进行比较。方法回顾分析181例(184只眼)增生性玻璃体视网膜病变(PVR)C2级以下改变的RRD行不放液的节段性外垫压手术与巩膜环扎加压、引流视网膜下液手术的临床资料。全部患者均为我院首诊病例,按手术中是否放液分为放液组和不放液组,分别分析各组PVR级别与视网膜解剖复位率的关系,并对二组的手术并发症、术后视力进行比较。181例患者术后随访时间2~48个月,平均8.6个月。结果放液组视网膜复位84只眼,手术成功率为91.3%;不放液组视网膜复位86只眼,手术成功率为93.5%。放液组和不放液组PVR不同级别(B,C级)视网膜复位率比较其差异无显著性意义(P>0.05)。而二组的手术并发症、术后视力进步率比较,不放液组手术并发症明显比放液组低,术后视力进步率较放液组高,其差别有显著性意义(P<0.01)。结论不放液的节段性外垫压手术与放液的巩膜环扎加压术复位率基本一致,但术后视力明显提高,手术并发症少,为手术步骤的重要改变,PVRC2级以下改变的RRD都可适用。     

下直肌牵引巩膜外垫压不放液手术治疗上方孔源性视网膜脱离

目的观察下直肌牵引及单纯巩膜外垫压不放液手术治疗上方孔源性视网膜脱离的临床效果。方法对上方孔源性视网膜脱离56例（56眼）术前进行下直肌缝线牵引制动，采用视网膜裂孔冷凝、巩膜环扎、外垫压及术中不放液的手术方法，对治疗结果进行分析。结果56例（56眼）经下直肌牵引制动3～5天后，52眼（92．86％）的视网膜脱离特别是上方球形脱离有明显消退，视网膜下液均有消散，其中28眼（50．00％）完全复位。53眼（94．64％）均行不放液术达到准确封闭孔源的目的。出院前治愈率为96．43％，未愈3．57％。结论下直肌缝线牵引制动可促进视网膜下液消退、平复，有利于术中裂孔准确定位、扣压位置适当，从而有效封闭裂孔。扩大了不放液手术适应范围，提高不放液手术成功率。     

孔源性视网膜脱离不放液手术的效果分析及影响因素

目的 分析孔源性视网膜脱离不放液手术的效果和影响视网膜下液吸收,视网膜复位的因素。方法 １２６例ＲＲＤ采用视网膜冷凝,巩膜不扎,外加压,不放液的手术方法。结果 １次手术后１１９眼视网膜完全复位,２眼再次不放液手术后视网膜复位,总复位率为９３．１％,ＳＲＦ术后２４ｈ吸收３７眼,７天内吸收１０１眼,术后视力明显提高。     

Adipokine levels in subretinal fluid from patients with rhegmatogenous retinal detachment

Adipokines have recently emerged as a novel group of mediators with important roles in inflammatory and immune responses and in the process of wound healing. This study investigated the involvement of several adipokines in the future development of proliferative vitreoretinopathy (PVR) following reattachment surgery for rhegmatogenous retinal detachment (RRD). A multiplex immunoassay was used to measure 6 different adipokines in 75 subretinal fluid samples collected during reattachment surgery for primary RRD. Twenty-one patients who developed a redetachment due to postoperative PVR after scleral buckling surgery (PVR group) were compared with age-, sex-, and storage-time-matched RRD samples from 54 patients with an uncomplicated postoperative course (RRD group). Levels of adiponectin (P?=?0.006), cathepsin S (P?=?0.001), and leptin (P?=?0.041) were significantly elevated in the PVR group as compared to the RRD group. Levels of tissue inhibitor of metalloproteinase (TIMP)-1 were significantly lower in the PVR group than in the RRD group (P?=?0.044). After correction for diabetes, body mass index (BMI), macular involvement, and preoperative PVR, the association between postoperative PVR development and adiponectin, cathepsin S, and TIMP-1 remained statistically significant (P?相似文献   

Endoscopy-guided subretinal fluid drainage in vitrectomy for retinal detachment

PURPOSE: To study the usefulness of endoscopy-guided subretinal fluid drainage in pars plana vitrectomy (PPV) for rhegmatogenous retinal detachment (RRD). PARTICIPANTS/METHODS: A prospective non-comparative study of a small number of RRD cases. The study involved examining 10 eyes of 10 patients with RRD that received PPV. Two eyes had hazy corneas, which hindered the observation by surgical microscopy. Fluid-gas exchange was performed and then subretinal fluid was drained through a primary retinal break guided by an endoscope. No drainage retinotomy was made. Each clinical feature was studied and the surgical outcome and complications were evaluated. RESULTS: All eyes had retinal reattachment by a single operation. No serious complication related to surgery was experienced. CONCLUSIONS: Endoscopy-guided subretinal fluid drainage is the safe and effective procedure in PPV for RRD.     

Persistent subretinal fluid after surgery for rhegmatogenous retinal detachment: hypothesis and review

Background

Persistent subretinal fluid after rhegmatogenous retinal detachment (RRD) surgery is responsible for delayed recovery, and may affect the final visual outcome. Cause, consequences, and treatment remain elusive.

Design

Literature review and case series.

Methods

We reviewed the pathophysiological principles and therapeutic options from the literature, and we report the results from a subretinal fluid cytology study. Nine eyes from nine patients with macula-involving RRD underwent surgical repair. The cellular content of subretinal fluid (SRF) was studied by electron microscopy and anti-rhodopsin immunostaining. All eyes were assessed postoperatively with optical coherence tomography for the detection of persistent submacular fluid (PSF) (Ethics Committee Ghent University Hospital, registration number B6702006169).

Results

Certain patient characteristics as well as surgical methods were implicated. PSF appears to occur more frequently in patients with longstanding detachments treated with buckling surgery. Several therapeutic options have been suggested but safety and efficacy remain unclear. We found PSF in three eyes on postoperative OCT scans, which corresponded to the three cell-rich subretinal samples.

Conclusions

PSF after successful RRD repair seems to be related to fluid composition. We hypothesize, in the absence of an effective treatment, that a modified surgical drainage, including a washout of the subretinal space, could evacuate the subretinal fluid more completely, and may prevent this complication.     

PaCE: a technique to avoid subretinal fluid drainage in retinal detachment surgery

PURPOSE: Subretinal fluid (SRF) drainage and thus the potential complications of this procedure during scleral buckling can be avoided by inducing SRF absorption preoperatively. The technique described in this series is named PaCE (Pneumatic Cryo Explant). METHODS: A total of 22 eyes of 22 patients with primary bullous rhegmatogenous retinal detachment (RRD) were included in this prospective non-comparative case trial. All satisfied specific inclusion criteria similar to those used in previous pneumatic retinopexy (PR) studies. Under direct visualization, 0.3 ml C3F8 100% was injected into the vitreous cavity through the pars plana. Postoperative posturing was encouraged. Retinopexy with either cryotherapy or laser was performed, combined with scleral buckling (SB) when the SRF was absorbed. Avoidance of SRF drainage and persistent reattachment of the retina at the end of the 12-month follow-up was considered a successful outcome. A change in vision by one line (logMAR) was considered significant. RESULTS: Resolution of SRF before retinopexy and the SB procedure was achieved in 20 of 22 eyes (90.9%) and hence SRF drainage was not required. Visual improvement was achieved in 95% of cases. One eye (4.5%) lost vision due to a total RD after gas injection (further surgery was not carried out). CONCLUSION: PaCE should be considered in any suitable case of primary RRD where SRF drainage is deemed necessary. The potential complications associated with this procedure are relatively less serious and it does not compromise the viability of subsequent procedures.     

Factors related to subretinal proliferation in patients with primary rhegmatogenous retinal detachment

PURPOSE: To evaluate factors related to subretinal proliferation in patients with primary rhegmatogenous retinal detachment (RD). METHODS: A total of 262 consecutive patients (267 eyes) with rhegmatogenous RD were evaluated retrospectively to determine factors associated with subretinal proliferation. RESULTS: Logistic regression analysis was used to identify the following factors associated with subretinal proliferation that caused retinal traction: number of quadrants detached (adjusted odds ratio [AOR] = 2.21), longer duration of RD (AOR = 1.52), younger patient age (AOR = 0.51), and presence of atrophic retinal breaks (AOR = 0.41). CONCLUSION: Atrophic retinal breaks, younger patient age, and RD of long duration and greater extent were associated with the presence of subretinal proliferation.     

孔源性视网膜脱离巩膜外加压术后视网膜下液的研究现状

孔源性视网膜脱离(rhegmatogenous retinal detachment,RRD)是严重的致盲性眼病,及时有效的手术治疗是治愈此病的关键。目前,治疗RRD的方法有玻璃体切除术(pars plana vitrectomy,PPV)和巩膜外加压术(scleral buckling surgery)两种术式。巩膜外加压术简单、有效,是治疗非复杂性视网膜脱离的首选术式,但术后视力恢复受很多因素的影响,其中视网膜下液的存在是影响术后视力恢复的重要原因。本文主要针对RRD巩膜外加压术后视网膜下液的研究现状进行归纳。     

孔源性视网膜脱离术中放液方式改进和应用

目的 总结并讨论孔源性视网膜脱离术中改良的放液方式及其临床效果.方法 选择孔源性视网膜脱离患者85例(87只眼),手术方式为“巩膜外冷凝+冷针穿刺放液+外加压(或联合环扎术)”.结果 一次手术治愈82只眼,占94.25％;经2次手术治愈3只眼,占3.45％,总的外路手术成功率97.70％.有2只眼出现放液时出血,经治痊愈,无其他并发症出现.结论 直接巩膜冷针放液方法简单、安全、并发症少,值得应用.