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Objective – In Tunisia, little data is available on shigellosis and this study was carried out by the laboratory of Microbiology, in the Sfax teaching hospital, to identify the epidemiological and bacteriological pattern of shigellosis in the Sfax region (south of Tunisia).Method – Between January 1994 and December 1995, all the stool cultures were assessed.Results – One hundred strains of Shigellae were isolated (1.5% of coprocultures). Shigella flexneri accounted for 80% of the strains. No Shigella dysenteria type 1 was isolated. Resistance rates were high for antibiotics such as: amoxicillin (45.5%), amoxicillin/clavulanic acid (31%), streptomycin (66.5%), tetracycline (61.8%), and chloramphenicol (44.4%). Low resistance rates were reported for trimethroprim/sulfamethoxazole (10%), cephalosporins and quinolones (⩽ 1%).  相似文献   

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Arbovirus diseases are mainly tropical affections caused by a heterogenic group of viruses with common epidemiological properties. About 130 known arboviruses belonging to about 12 different virus families are of human or veterinarian medical importance. Many others are not pathogenic but can be interesting models for fundamental virological studies. Arboviruses survive in nature by biological transmission between vertebrate hosts and hematophage arthropoda. Arboviruses reproduce on these without change to their life or fecundity. They are transmitted through bite or sting of infected arthropoda to receptive vertebrates inducing an early and transitional viremia. A more or less complex cycle usually follows: virus, arthropoda vector, vector, vertebrate host. According to the vector’s ecology, each arbovirus is present in a specific area and is always likely to invade a non-endemic zone. The arthropoda in question are ticks, mosquitoes, phlebotomes, or Culicoides (Ceratopogonidae). Vertebrates either spread or amplify the viremia or they are accidental hosts or epidemiological dead-ends. Three types of clinical presentations are described: febrile polyalgia (“dengue-like” syndromes); hemorrhagic fever (frequently severe evolution); meningo-encephalitis (frequently severe evolution ending by death or recovery with severe neurological sequels). Various arboviruses are responsible for the same clinical presentations; but a same virus can induce several types of syndromes which stress the importance of laboratory diagnosis, based on the virus identification and specific serological tests. Prophylaxis relies on vaccination: yellow fever, tick borne encephalitis, Japanese encephalitis and fighting against vectors. New vaccines are being studied but not on the market yet.  相似文献   

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Objective

To evaluate the iodine content and microbiological contamination of salts sold at Dantokpa, the Benin's largest market, in order to assess quality throughout the distribution chain.

Materials and methods

From October to November 2016, 190 salt samples were collected from 18 wholesalers and 172 salt dealers at the Dantokpa market in the town of Cotonou. Iodine content was qualitatively determined using the MBI-Kit and quantitatively by spectrophotometry. The microbiological quality assessment involved 30 samples randomly selected to count Total Mesophilic Aerobic Flora (TMAF).

Results

With the MBI Kit, 47.9 % of samples did not contain iodine. By spectrophotometry, 40 % of the salts had an iodine content equal to 0 ppm, 59.5 % a content < 15 ppm and 0.53 % of the samples an iodine content ≥ 15 ppm. None of the salt samples met the Beninese recommendations of iodized salt for sale (20–60 ppm). For microbiological quality, 100 % of the samples were contaminated with microorganisms, which were staphylococci in 10 %.

Conclusion

This study showed that the dietary salts sold at the Dantokpa market are not adequately iodized. In addition, some samples are contaminated with halophilic microorganisms. These disturbing results highlight the need for an immediate strengthening of the salt iodization strategy in Benin while including sellers’ awareness for a better hygiene.  相似文献   

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Objective – The epidemiological variations of visceral leishmaniasis (VL) in Tunisia are studied along with the clinical specificity of the disease in adults.Patients and methods – Six cases of parasitologically confirmed adult VL are described.Results – All patients tested negative for HIV. Clinical manifestations were not always evocative. In fact, two patients were apyretic and splenomegaly was absent in three. Biological disorders were more frequently noted, especially increase of erythrocyte sedimentation rate, anemia, and hyper γ globulinemia.Conclusion – The epidemiological profile of VL in Tunisia is slowly becoming identical to the North Mediterranean model characterized by a high proportion of adult cases. This may be due to the multiplication of immunodepressing factors and the decrease of specific immunization following the less frequent human-parasite contact during childhood.  相似文献   

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