共查询到20条相似文献,搜索用时 15 毫秒
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A. P. M. v. d. Meijden P. A. Steerenberg W. H. de Jong M. J. J. T. Bogman W. F. J. Feitz B. T. Hendriks F. M. J. Debruyne E. J. Ruitenberg 《Urological research》1986,14(4):207-210
Summary Intravesical and intradermal application of B.C.G. (Bacillus Calmette Guérin) has proven to be effective in the prophylaxis of recurrence of superficial bladder carcinoma after transurethral resection and in the treatment of carcinoma in situ (C.I.S.) in man. Different strains of B.C.G. have been used for this purpose. In this article a new strain of B.C.G. (B.C.G.-R.I.V.M.) has been tested to assess its toxicity. The effects of intravesical and intradermal application of B.C.G.-R.I.V.M. were studied on normal and on coagulated canine urothelium. In this study no general side effects of B.C.G.-R.I.V.M. were seen. Only minor local changes occurred in the bladder wall. Small granulomas were found in the suburothelial tissue. No granulomas or signs of active inflammation were observed in the pelvic lymphnodes, spleen and liver. Because B.C.G.-R.I.V.M. seemed to be a safe agent in the dog we have started to use it for prophylaxis in superficial bladder cancer in man.Grant recipient of the Koningin Wilhelmina Fonds (Dutch Cancer Foundation) 相似文献
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P C Leung 《The Journal of hand surgery》1979,4(5):409-411
Venous congestion in a replanted or transplanted digit can be detected, even before any obvious color changes, by the "throbbing" elicited by pinching the digit between the thumb and finger of the examiner until the skin blanches. Releasing the pressure slowly, a sensation of throbbing will be felt synchronous with the patient's pulse rate. The sign disappears when venous congestion is relieved or when swelling persists and increases enough to lessen the arterial inflow. 相似文献
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目的:探讨成人先天性胆管扩张症的流行病学特征和诊疗经验。方法:联合检索维普数据库和中国期刊网等多家中文数据库中1990年1月~2010年11月有关成人先天性胆管扩张症的文章,总结分析成人先天性魍管扩张症的流行病学特征和诊治经验。结果:中国近2{年共报道5146例成人先天性胆管扩张症,有准确年龄及平均年龄报道4298例,平均年龄34.84岁,男女比例约为1:2.55,43.44%分布在华东地区,68.38%有不同程度腹痛表现,25.22%有发热或高热症状,32,46%有不同程度黄疸,18.31%可触及腹部包块,具有典型三联征表现患者占15.98%。Todani分型I型8041%,II型4.27%,III型123%,IV型1155%,V型占2,54%。手术治疗为主要治疗手段,胆管囊肿切除加胆管空肠Roux—en—Y吻合术占71.63%;术后并发症以胆管炎症状为主,发生率为12.24%;术后随访率83.55%,治愈率8684%。结论:成人先天性胆管扩张症女性多发,其中以华东地区较多,Todani分型I型为主,囊肿切除加胆肠Roux—en—Y吻合术为主要治疗手段。 相似文献
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动力髋螺钉治疗股骨粗隆间骨折54例分析 总被引:6,自引:0,他引:6
目的 总结动力髋螺钉(Dynamic Hip Screw,DHS)治疗股骨粗隆间骨折的经验。方法 54例股骨粗隆间骨折采用DHS内固定手术治疗(A1型27例,A2型20例,A3型7例)。结果 经4~36个月平均7个月随访疗效满意。结论 术中尽可能恢复股骨粗隆后内侧皮质的完整性;标准的粗螺钉固定位置及加强术后功能锻炼是取得良好疗效的关键。 相似文献
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超声介导腹腔神经节去除治疗胰腺癌疼痛 总被引:4,自引:0,他引:4
目的:评价超声介导腹腔神经节去除在胰腺癌疼痛中的疗效。方法:采用B超定位,实时超声动态监测经皮穿刺,于腹腔动脉干根部旁侧注入无水乙醇15ml,对97例胰腺癌痛患者实施腹腔神经节去除术。比较治疗前后疼痛的视觉模拟评分(VAS)以及血清SP水平变化。结果:97例中1例穿刺失败, 成功率98.7%,无急性胰腺炎、胰瘘及出血等穿刺并发症;VAS及SP较术前明显降低(P<0.01,P<0.05),有效率87.5%,显效率76.1%,12例无效。结论:超声介导腹腔神经节去除术安全可靠,能显著减轻胰腺癌疼痛。 相似文献
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R W Pho 《The Journal of hand surgery》1979,4(1):11-15
A local composite neurovascular island flap to provide stable skin cover with good soft tissue padding and sensibility for extensive pulp loss of the thumb was used in five patients. The island flap included the dorsoradial branches of the radial digital neurovascular bundle of the thumb. 相似文献
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Car seat belts and the eye 总被引:1,自引:0,他引:1
W O Taylor 《Injury》1974,6(1):3-6
In a series of 22 successive victims of car accidents with eye injuries sufficiently severe to require their admission to an Eye Unit in Ayrshire, it was noted that not a single one had been wearing a seat belt, nor have any persons involved in similar accidents who were wearing seat belts, required to be admitted for any eye injury over a 3-year period.It is suggested that the wearing of seat belts could prevent injuries to the eyes, at least where the car frame remains intact. 相似文献
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目的:研究TIPS治疗对门静脉高压症患者食管、胃底组织内微血管生成的影响,探讨血管生成在门静脉高压症食管、胃底静脉曲张形成中的作用。方法:取门静脉高压症Sugiura术患者的食管贲门吻合圈标本78例。(1)PHT组:术前未行TIPS治疗。食管组织118例,胃组织25例;(2)TIPS组:术前曾行TIPS治疗,食管组织5例,胃组织12例。正常食管组织10例、胃组织8例作为对照组。应用免疫组化技术分别检测食管胃底组织内的微血管密度。结果:食管胃底组织微血管高密度区主要位于粘膜固有层,其次为粘膜下层。粘膜固有层微血管密度3组差别无统计学意义(P>0.05);粘膜下层微血管密度PHT组明显高于正常组(P<0.01)和TIPS组(p<0.05),TIPS组和正常组差别无统计学意义(P >0.05)。结论:食管胃底组织内的微血管密度与门静脉压力改变有关。门静脉高压时,食管胃底组织粘膜下层血管生成活跃,可能参与了食管胃底粘膜下静脉曲张的形成;经TIPS治疗后,粘膜下层血管生成减少。 相似文献
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T raumatic avulsion of the gall bladder, and its subsequent dislodgement into the pelvis has not previously been reported. The case described records severe damage to the biliary system without much damage to other viscera. 相似文献
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腔内激光联合点式潜行剥脱治疗下肢浅静脉曲张——五年随访报告 总被引:1,自引:0,他引:1
目的:应用腔内激光(EVLT)联合点式潜行剥脱治疗下肢浅静脉曲张,通过5年随访评价其远期疗效。方法:收治下肢浅静脉曲张患者56例,共88条患肢。行常规EVLT,并同期利用腹腔镜手术分离钳进行点式潜行曲张静脉团剥脱。结果:手术时间平均45 min,失血平均70 mL。5年随访发现静脉曲张复发6例(10.7%),再次手术4例(7.1%),3例术后大隐静脉根部未完全闭塞,另3例为交通支原因复发。结论:ELVT联合点式潜行剥脱治疗下肢静脉曲张相对简单、微创效果好、远期疗效较好,复发率尚可接受。 相似文献
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The pathological changes associated with actinomycosis in mice caused by Arachnia propionica have been described. Abscess formation in the liver was the predominant gross and microscopic alteration produced by this organism. Liver abscesses were evident 3 days post challenge and simply enlarged with time. There was no evidence of spontaneous abscess healing. Additionally, multinucleated giant cells were found in an enlarged spleen. 相似文献
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《Urologic oncology》2015,33(4):167.e1-167.e6
ObjectiveTo investigate whether a combination of variables from each nephrometry system improves performance. There are 3 first-generation systems that quantify tumor complexity: R.E.N.A.L. nephrometry score (RNS), preoperative aspects and dimensions used for an anatomical (PADUA) classification (PC), and centrality index (CI). Although each has been subjected to validation and comparative analysis, to our knowledge, no work has been done to combine variables from each method to optimize their performance.Patients and methodsScores were assigned to each of 276 patients undergoing partial nephrectomy (PN) or radical nephrectomy (RN). Individual components of all 3 systems were evaluated in multivariable logistic regression analysis of surgery type (PN vs. RN) and combined into a “second-generation model.”ResultsIn multivariable analysis, each scoring system was a significant predictor of PN vs. RN (P<0.0001). Of the first-generation systems, CI was most highly correlated with surgery type (area under the curve [AUC] = 0.91), followed by RNS (AUC = 0.90) and PC (AUC = 0.88). Each individual component of these scoring systems was also a predictor of surgery type (P<0.0001). In a multivariable model incorporating each component individually, 4 were independent predictors of surgery type (each P<0.005): tumor size (RNS and PC), nearness to the collecting system (RNS), location along the lateral rim (PC), and centrality (CI). A novel model in which these 4 variables were rescaled outperformed each first-generation system (AUC = 0.91).ConclusionsOptimization of first-generation models of renal tumor complexity results in a novel scoring system, which strongly predicts surgery type. This second-generation model should aid comprehension, but future work is still needed to establish the most clinically useful model. 相似文献
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Juan A. Tovar G.Hossein Mahour Shelby W. Miller Hart Isaacs Carol Nye Smith 《Journal of pediatric surgery》1976,11(1):23-31
Healthy 6–8-wk-old New Zealand white rabbits were injected with chromium-chloride- or sodium-chromate-labeled E. coli endotoxin after rapid infusion (10 ml/kg in 1 hr) or slow and repeated infusions (40 ml/kg daily for 7 consecutive days) of 10% Intralipid. Endotoxin clearance rates and RES organ uptakes were determined and the results were compared with those of the controls treated with correspondingly equal volumes of 5% instead of fat.In the acute experiment, the clearance rates were similar in all animals during the first 15 min following endotoxin injection. After this phase, however, experimental animals had faster endotoxin clearance and eventually higher organ uptakes than the controls. In the chronic experiment, there was no significant difference in endotoxin clearance rates or total and per-gram organ uptakes between experimental and corresponding control animals infused with 5% instead of fat.Experimental animals, particularly those having received multiple infusions of fat emulsion, showed deposition of polarizable brown pigment inside and outside the reticuloendothelial cells in the liver, spleen, and bone marrow. None of the controls had these pigments in their organs. 相似文献