护理干预对慢性萎缩性胃炎临床疗效的影响

目的研究对慢性萎缩性胃炎（CAC）患者实施临床护理干预的疗效观察及影响。方法选取2011年1—12月间入院治疗的CAC患者86例,随机均等分为实验组和对照组。其中对照组采用常规的药物治疗和护理,实验组在对照组基础上采用针对患者治病自身的护理干预方案。观察两组患者的治疗效果。结果实验组的有效率为97.6%,对照组的有效率为86%。结论对慢性萎缩性胃炎的患者实施自身护理干预,能够调节患者情志,帮助其更好地战胜疾病,对预后也有十分积极的作用。     

护理干预对慢性萎缩性胃炎治疗的作用观察

目的：分析护理干预对慢性萎缩性胃炎治疗的积极作用。方法选取2013年10月—2014年10月期间在我院治疗的慢性萎缩性胃炎患者73例,按照随机数字表法将其分为对照组（n=30）和观察组（n=43）,对照组予以常规的护理干预,观察组予以综合性护理干预。比较2组患者的临床护理干预效果。结果对照组总有效率为77%,观察组总有效率为93%,组间比较差异显著（P<0.05）。对照组满意度为73.3%,观察组满意度为95.3%,组间比较差异显著（P<0.05）。结论对慢性萎缩性胃炎患者予以综合性护理干预,能有效提高患者的治疗效果及护理满意度,具有临床应用价值。     

人性化护理干预在90例慢性萎缩性胃炎患者中的应用效果分析

目的探讨人性化护理干预在慢性萎缩性胃炎患者中的应用效果。方法选取于2012年2月—2013年12月在该院接受治疗的慢性萎缩性胃炎患者90例作为研究对象,将患者随机分为对照组和观察组,对照组采取常规治疗和常规护理,观察组在常规治疗和常规护理基础上再给予人性化护理干预,如对患者进行心理护理、饮食护理以及出院指导等,比较两组之间的临床效果。结果观察组的临床效果明显高于对照组,总有效率为达到了95.55%,对照组总有效率为77.78%,观察组满意的有30例、一般满意14例、不满意1例;对照组满意的有19例、一般满意12例、不满意14例。两组间比较差异有统计学意义。结论实施人性化护理干预措对治疗慢性萎缩性胃炎患者具有重要作用,值得推广使用。     

慢性萎缩性胃炎应用整体护理干预的效果研究

目的:研究慢性萎缩性胃炎应用整体护理干预的临床护理效果。方法:选择2013年1月至2014年12月我院收治的70例慢性萎缩性胃炎患者作为研究对象,根据不同的护理方法,把70例患者分为对照组与观察组,每组各35例。对照组实施常规护理,观察组实施整体护理干预,护理半年后,比较两组患者的临床护理效果。结果:观察组治疗总有效率91.4%,对照组治疗总有效率71.4%,观察组治疗效果明显优于对照组,两组对比差异显著(P0.05)。结论:慢性萎缩性胃炎患者应用整体护理干预后护理效果理想,可以提高患者的临床治疗效果,利于患者及早康复出院,值得推广应用。     

益气养阴活血方在慢性萎缩性胃炎中的临床效果研究

目的：探究益气养阴活血方在慢性萎缩性胃炎的临床治疗效果。方法随机选取该院2015年6月-2016年6月110例慢性萎缩性胃炎患者,均给于常规护理,其中对照组55例给予维酶素、胃蛋白酶口服液等常规西医治疗,实验组55例患者给予益气养阴活血方进行治疗。1个月后比较两组患者治疗前后的临床治疗效果。结果实验组有28例治愈,实验组总有效率为96.4%,明显高出对照组总有效率为87.3%,P<0.05,差异有统计学意义。结论根据慢性萎缩性胃炎患者的临床表现,病程进展、体质状况进行系统的把握,辨证论治,给予益气养阴活血方治疗,能有效提高患者的临床治愈率,缓解慢性萎缩性胃炎疾病进展,对减轻患者胃痛、胃酸等症状,提高患者的生活质量具有着重要的意义。     

系统护理应用于慢性萎缩性胃炎患者中的疗效观察

目的研究对慢性萎缩性胃炎患者实施系统护理干预的临床效果。方法选取自2014年3月至2017年1月收治的慢性萎缩性胃炎患者80例,按不同的护理干预分成对照组和观察组,每组各40例,对照组患者采用常规护理,观察组患者采用系统护理干预,比较两组患者对护理服务的满意度及临床效果。结果观察组患者对护理服务的满意度为100%(40/40),护理的有效率为95%(38/40),对照组患者对护理服务的满意度为68%(27/40),护理的有效率为75%(30/40),观察组患者对护理服务的满意度和临床效果优于对照组,差异有统计学意义(P0.05)。结论对慢性萎缩性胃炎患者进行系统护理干预,可以有效地提高其治疗的依从性,保障了患者对护理服务的满意度和临床效果。     

中医治疗慢性萎缩性胃炎临床观察

目的:研究探讨中医治疗慢性萎缩性胃炎的临床治疗效果。方法:将我院2012年8月-2014年9月收治的慢性萎缩性胃炎患者120例按照统计学原理分成对照组和观察组,两组患者例数相同。对照组患者采用常规的西医进行治疗,观察组患者实行中医治疗,比较两组患者临床治疗效果。结果:在本次的研究活动中发现,观察组患者治疗的有效率为96.7%,而对照组患者的治疗有效率仅为76.7%,数据符合统计学差异(P0.05)。结论:针对慢性萎缩性胃炎患者采用中医治疗慢性萎缩性胃炎,有助于患者病情的改善,有效消除患者胃部的炎症,促进患者胃部的健康。从这就可以看出,中医治疗慢性萎缩性胃炎具有良好的临床效果,是治疗慢性萎缩性胃炎的一种有效途径,值得在临床上推广使用。     

慢性萎缩性胃炎应用整体护理干预的效果研究

目的:研究慢性萎缩性胃炎用整体护理干预的效果.方法:回顾性剖析2016年1月至次年4月该院接诊的64例慢性萎缩性胃炎病患的病历资料,其中有32例病患应用整体护理(实验组),余下32例病患均接受常规护理(对照组).观察两组护理干预后病情的控制效果,比较患者满意度等指标.结果:实验组的护理总有效率为93.75％,明显比对照组的71.87％高,组间差异显著(P＜0.05).实验组的患者满意度为96.87％,比对照组的75.0％更高,组间差异显著(P＜0.05).结论:对慢性萎缩性胃炎病患积极应用整体护理干预措施,有助于改善临床护理质量,提高患者病情控制的效果.     

规范性治疗对慢性萎缩性胃炎患者的疗效观察

目的研究规范性治疗对慢性萎缩性胃炎患者的疗效。方法研究时间为2015年9月至2017年3月,研究对象为106例本院收治确诊的慢性萎缩性胃炎患者,按照随机数字表法将其分为对照组(n=53)和实验组(n=53),给予对照组患者常规用药治疗,给予实验组患者规范性治疗,治疗后观察两组患者的临床治疗总有效率、不良反应发生率、术后复发率、胃粘膜病理表现积分、幽门螺杆菌清除率。结果临床治疗总有效率对比显示实验组明显高于对照组,P0.05。不良反应发生率对比显示实验组明显组低于对照组,P0.05。术后复发率对比显示实验组明显低于对照组,P0.05。胃粘膜病理表现积分对比显示实验组低于对照组,P0.05。幽门螺杆菌清除率对比显示实验组明显高于对照组,P0.05。结论规范性治疗对慢性萎缩性胃炎患者的疗效显著,生存率高,值得临床推广应用。     

慢性萎缩性胃炎的临床检测与治疗方法研究

目的探究慢性萎缩性胃炎的临床检测与治疗措施。方法选取慢性萎缩性胃炎患者100例作为本次研究对象,采用动态随机化法将患者分为2组,实验组接受中西医结合治疗,对照组仅接受西医治疗,对比2组慢性萎缩性胃炎患者治疗效果的差异性。结果实验组慢性萎缩性胃炎患者经中西结合治疗的总有效率(92.00%)较对照组经单纯西医治疗的总有效率(72.00%)优(P0.05)。同时,实验组慢性萎缩性胃炎患者幽门螺杆菌转阴率与对照组差异显著(P0.05),结论胃镜在慢性萎缩性胃炎检测中的应用效果较好,患者接受中西医结合治疗利于不良症状的改善。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.