Effects of prolonged exercise at a similar percentage of maximal oxygen consumption in trained and untrained subjects

Summary Six trained male cyclists and six untrained but physically active men participated in this study to test the hypothesis that the use of percentage maximal oxygen consumption (% , as a normalising independent variable is valid despite significant differences in the absolute of trained and untrained subjects. The subjects underwent an exercise test to exhaustion on a cycle ergometer to determine and lactate threshold. The subjects were grouped as trained (T) if their exceeded 60 ml ·kg^–1 ·min^–1, and untrained (UT) if their was less than 50 ml · kg^–1 · min-^–1. The subjects were required to exercise on the ergometer for up to 40 min at power outputs that corresponded to approximately 50% and 70% The allocation of each exercise session (50% or 70% was random and each session was separated by at least 5 days. During these tests venous blood was taken 10 min before exercise (–10 min), just prior to the commencement of exercise (–10 min), after 20 min of exercise (20 min), at the end of exercise and 10 min postexercise (+ 10 min) and analysed for concentrations of cortisol, [Na⁺], [K⁺], [CI^–], glucose, free fatty acid, lactate [la-], [NH₃], haemoglobin [Hb] and for packed cell volume. The oxygen consumption ( ) and related variables were measured at two time intervals (14–15 and 34–35 min) during the prolonged exercise tests. Rectal temperature was measured throughout both exercise sessions. There was a significant interaction effect between the level of training and exercise time at 50% for heart rate ( _c:) and venous [la^–]. At 70% and ventilation ( ) for the T group and and carbon dioxide production for the UT group increased significantly with time and there was a significant interaction effect forf _c, ]Ia^–1], [Hb] and [NH₃]. The change in body mass at 50% and 70% was significantly greater in the T group. The present study found that when two groups of male subjects with different absolute exercised at a similar percentage of some effector responses were significantly different, questioning the validity of selecting % as a normalising independent variable.     

Determination of body heat storage in clothing: calorimetry versus thermometry

Two methods of estimating body heat storage were compared under differing conditions of clothing, training, and acclimation to heat. Six male subjects underwent 8 weeks of physical training [60–80% of maximal aerobic power ( ) for 30–45 min · day–, 3–4 days · week^–1 at < 25 °C dry bulb (db)] followed by 6 consecutive days of heat acclimation (45–55% for 60 min · day^–1 at 40°C db, 30% relative humidity)]. Nine other male subjects underwent corresponding periods of control observation followed by heat acclimation. Before and after each treatment, subjects walked continuously on a treadmill (1.34 m · s^–1, 2% grade) in a climatic chamber (40°C db, 30% relative humidity) for an average of 118 min (range 92–120 min) when wearing normal light combat clothing and for an average of 50 min (range 32–68 min) when wearing protective clothing resistant to nuclear, biological, and chemical agents. The heat storage was determined calorimetrically (by the balance of heat gains and losses) and thermometrically [by the conventional equations, using one or two set(s) of relative weightings for the rectal temperature (T _re) to mean skin temperature _sk of 4:1 and 4:1, 2:1 and 4:1, or 2:1 and 9:1 in thermoneutral and hot environments, respectively]. _sk was calculated from 12-site measurements, weighted according to the regional distribution of body surface area and the first eigenvectors of principal component analysis. There were only minor differences (< 5%) between the heat storage values calculated by given weighting factors forT _re and _sk, whether the individual coefficients were derived from estimates of regional surface area or principal component methodologies. When wearing normal clothing, no significant differences were found between the two estimates of heat storage (calorimetry vs thermometry with an invariant relative weighting of 4:1) in any experimental condition, with one specific exception: when wearing protective clothing, thermometry underestimated the heat storage by 24–31%. This underestimation was attenuated by using two sets of relative weightings of 2: 1 and 4: 1 or 2: 1 and 9: 1. The results suggest that when subjects wearing protective clothing are transferred from thermoneutral to hot environments, the accuracy of thermometric estimates of heat storage can be improved by using two sets of weighting factors forT _re and _sk     

A method for determining the maximal steady state of blood lactate concentration from two levels of submaximal exercise

The aim of this study was to estimate the characteristic exercise intensity _CL which produces the maximal steady state of blood lactate concentration (MLSS) from submaximal intensities of 20 min carried out on the same day and separated by 40 min. Ten fit male adults [maximal oxygen uptake _max 62 (SD 7) ml · min^–1 · kg^–1] exercisOed for two 30-min periods on a cycle ergometer at 67% (test 1.1) and 82% of _max (test 1.2) separated by 40 min. They exercised 4 days later for 30 min at 82% of _max without prior exercise (test 2). Blood lactate was collected for determination of lactic acid concentration every 5 min and heart rate and O₂ uptake were measured every 30 s. There were no significant differences at the 5th, 10th, 15th, 20th, 25th, or 30th min between , lactacidaemia, and heart rate during tests 1.2 and 2. Moreover, we compared the exercise intensities _CL which produced the MLSS obtained during tests 1.1 and 1.2 or during tests 1.1 and 2 calculated from differential values of lactic acid blood concentration ([1a^–]_b) between the 30th and the 5th min or between the 20th and the 5th min. There was no significant difference between the different values of _CL [68 (SD 9), 71 (SD 7), 73 (SD 6),71 (SD 11) % of _max (ANOVA test,P<0.05). Four subjects ran for 60 min at their _CL determined from periods performed on the same day (test 1.1 and 1.2) and the difference between the [la^–]_b at 5 min and at 20 min ( ([la^–]_b)) was computed. The [la^–]_b remained constant during exercise and ranged from 2.2 to 6.7 mmol · l^–1 [mean value equal to 3.9 (SD 1) mmol · l^–1]. These data suggest that the _CL protocol did not overestimate the exercise intensity corresponding to the maximal fractional utilization of _max at MLSS. For half of the subjects the _CL was very close to the higher stage (82% of _max where an accumulation of lactate in the blood with time was observed. It can be hypothesized that _CL was very close to the real MLSS considering the level of accuracy of [la^–]_b measurement. This study showed that exercise at only two intensities, performed at 65% and 80% of _max and separated by 40 min of complete rest, can be used to determine the intensity yielding a steady state of [la^–1]_b near the real MLSS workload value.     

Use of oxygen uptake recovery curve to predict peak oxygen uptake in upper body exercise

A group of 18 well-trained white-water kayakers performed maximal upper body exercise in the laboratory and during.a field test. Laboratory direct peak oxygen uptake ( ) values were compared, firstly by a backward extrapolation estimation and secondly by an estimation calculated from measured during the first 20 s of exercise recovery. Direct peak correlated with backward extrapolation (r=0.89), but the results of this study showed that the backward extrapolation method tended to overestimate significantly peak by [0.57 (SD 0.31) 1·min^–1 in the laboratory, and 0.66 (SD 0.33) 1·min^–1 in the field,P<0.001]. The measured during the first 20 s of recovery, whether the exercise was performed in the laboratory or in the field, correlated well with the laboratory direct peak (r=0.92 andr=0.91, respectively). The use of the regression equation obtained from field data _2f20s, that is peak ₂=0.23+1.08 _2f20s, gave an estimated peak ₂, the mean difference of which compared with direct peak was 0.22 (SD 0.13) 1·min^–1. In conclusion, we propose the use of a regression equation to estimate peak from a single sample of the gas expired during the first 20 s of recovery after maximal exercise involving the upper part of the body.     

The influence of inspired oxygen on the oxygen uptake response to ramp exercise

The relation between and work rate (WR) was examined in seven male subjects who performed ramp (1 W·3 s^–1) two-legged cycle ergometry to exhaustion while inspiring either hypoxic (12% O₂), normoxic (21% O₂), or hyperoxic (40% O₂) air. The anaerobic threshold was estimated from respiratory gas exchange data and is thus referred to as the respiratory gas exchange threshold (RGET). Prior to the RGET, the was greater under normoxic [mean (SD); 10. 19(1.04) ml O₂·min^–1·W^–1] and hyperoxic [10.44 (0.72)] conditions compared with hypoxia [9.34 (0.89)]. Above the RGET, the for hypoxia [8.91 (0.63)], normoxia [10.40 (0.77)], and hyperoxia [11.08 (0.48)] were all significantly different from each other. These data indicated that for two-legged, cycle, ramp ergometry in normoxia below the RGET, both the and response time was constant. Above the RGET, the normoxic response was the net result of a declining and a longer response time to the unsteady state character of a ramp exercise protocol.     

Specificity of physiological adaptation to endurance training in distance runners and competitive walkers

Summary The present study was designed to evaluate the specificity of physiological adaptation to extra endurance training in five female competitive walkers and six female distance runners. The mean velocity ( ) during training, corresponding to 4 mM blood lactate [onset of blood lactate accumulation (OBLA)] during treadmill incremental exercise (training was 2.86 m·s^–1 SD 0.21 in walkers and 4.02 m·s^–1, SD 0.11 in runners) was added to their normal training programme and was performed for 20 min, 6 days a week for 8 weeks, and was called extra training. An additional six female distance runners performed only their normal training programme every day for about 120 min at an exercise intensity equivalent to their lactate threshold (LT) (i.e. a running of about 3.33 m·s^–1). After the extra training, there were statistically significant increases in blood lactate variables (i.e. oxygen uptake ( O₂) at LT, at LT, O₂ at OBLA, at OBLA; P<0.05), and running F for 3,000m (P<0.01) in the running training group. In the walking training group, there were significant increases in blood lactate variables (i.e., at LT, at OBLA; P<0.05), and walking economy. In contrast, there were no significant changes in lactate variables, running and economy in the group of runners which carried out only the normal training programme. It is suggested that the changes in blood lactate variables such as LT and OBLA played a role in improving F of both the distance runners and the competitive walkers. Furthermore, the significant improvement in walking economy brought about by extra endurance training might be a specific phenomenon for competitive walkers compared to runners.     

Independence of ventilation and blood lactate responses during graded exercise

The effect of power output increment, based on an increase in pedal rate, on blood lactate accumulation during graded exercise is unknown. Therefore, in the present study, we examined the effect of two different rates of power output increments employing two pedal rates on pulmonary ventilation and blood lactate responses during graded cycle ergometry in young men. Males (n=8) with an mean (SD) peak oxygen uptake of 4.2 (0.1) 1·min^–1 served as subjects. Each subject performed two graded cycle ergometer tests. The first test, conducted at 60 rev· min^–1, employed 4 min of unloaded pedaling followed by a standard power output step increment (SI) of 60 W every 3rd min. The second test, conducted at 90 rev·min^–1, employed 4 min of unloaded pedaling followed by a high power output step increment (HI) of 90 W every 3rd min. Venous blood was sampled from a forearm vein after 5 min of seated rest, 4 min of unloaded pedaling, and every 3rd min of graded exercise. Peak exercise values for heart rate, oxygen uptake ( O₂), and ventilation ( _E) were similar (P > 0.05) for SI and HI exercise, as was the relationship between _E and O₂, and between _E and carbon dioxide production ( CO₂). However, the relationship between blood lactate concentration and O₂ was dissimilar between SI and HI exercise with blood lactate accumulation beyond the lowest ventilatory equivalent of oxygen, and peak exercise blood lactate concentration values significantly higher (P < 0.05) for SI [12.8 (2.6) mmol·l^–1] compared to HI [8.0(1.9) mmol·l^–1] exercise. Our findings demonstrate that blood lactate accumulation and _E during graded exercise are dissociated. Blood lactate accumulation is influenced by the rate of external power output increment, while _E is related to O₂ and CO₂.     

The relationship between test protocol and the development of exercise-induced hypoxemia (EIH) in highly trained athletes

Healthy male endurance-trained cyclists [n = 11, age = 27.3 (3.9) years; mass = 73.0 (9.3) kg; height = 180.5 (6.9) cm; maximal oxygen consumption ( = 71.1 (5.8) ml · kg^–1 · min^–1, mean ± (SD)] were recruited to assess the relationship between test protocol and the development of desaturation of arterial hemoglobin with oxygen, during incremental exercise tests to maximal aerobic capacity . All subjects demonstrated resting pulmonary function within normal limits [forced vital capacity (FVC) = 6.0 (0.9); forced expiratory volume (FEV_1.0) = 4.9 (0.6); FEV_1.0/FVC = 0.8 (0.1)] and completed three ramped tests (Mijnhardt KEM-3 electronically braked cycle ergometer) beginning at 0 W with increments of either 20, 30 or 40 W · min^–1. All periods of testing were separated by a minimum of 72 h. , peak minute ventilation (Medical Graphics, CPX-D), peak heart rate (ƒ_cpeak)), peak power output , and minimum percentage arterial oxyhemoglobin saturation (%S _aO_2min) (Omeda Biox 3740 pulse oximeter) were determined. There were no significant differences (p > 0.05) in [191.5 (26.2), 196.0 (24.4), 194.3 (23.9) 1 · min^–1] ƒ_cpeak [191.4 (7.0), 190.3 (5.5), 187.8 (5.9) beats · min^–1], [5.0 (0.5), 5.1 (0.4), 5.1 (0.5) 1 · min^–1] or %S _aO_2min [89.5 (1.5), 89.6 (1.3), 90.0 (2.3)] between protocols. The 20-W protocol [417 (27) W] demonstrated significantly lower (P < 0.05) than the 30-W [434 (36) W] and 40-W [453 (38) W] protocols, indicating that peripheral fatigue may play an important factor in response to these tests. The results of this study demonstrate that arterial desaturation occurs as a result of intense exercise in highly trained athletes independent of the rate of attainment of .     

Oxygen uptake during swimming in a hypobaric hypoxic environment

Summary The purpose of this study was to determine oxygen uptake O₂) at various water flow rates and maximal oxygen uptake ( O_2max) during swimming in a hypobaric hypoxic environment. Seven trained swimmers swam in normal [N; 751 mmHg (100.1 kPa)] and hypobaric hypoxic [H; 601 mmHg (80.27 kPa)] environments in a chamber where atmospheric pressure could be regulated. Water flow rate started at 0.80 m · s^–1 and was increased by 0.05 m· s^–1 every 2 min up to 1.00 m · s^–1 and then by 0.05 m · s^–1 every minute until exhaustion. At submaximal water flow rates, carbon dioxide production ( CO₂), pulmonary ventilation ( _E) and tidal volume (V _T) were significantly greater in H than in N. There were no significant differences in the response of submaximal O₂, heart rate (f _c) or respiratory frequency (f _R) between N and H. Maximal _E,f _R,V _T,f _c blood lactate concentration and water flow rate were not significantly different between N and H. However, VO_2max under H [3.65 (SD 0.11) l · min^–1] was significantly lower by 12.0% (SD 3.4) % than that in N [4.15 (SD 0.18) l · min^–1] . This decrease agrees well with previous investigations that have studied centrally limited exercise, such as running and cycling, under similar levels of hypoxia.     

The energetics of middle-distance running

Summary In order to assess the relative contribution of aerobic processes to running velocity (v), 27 male athletes were selected on the basis of their middle-distance performances over 800, 1500, 3000 or 5000 m, during the 1987 track season. To be selected for study, the average running velocity corresponding to their performances had to be superior to 90% of the best French of the season. Maximum O₂ consumption and energy cost of running (C) had been measured within the 2 months preceding the track season, which, together with oxygen consumption at rest allowed us to calculate the maximalv that could be sustained under aerobic conditions: . The treadmill runningv corresponding to a blood lactate of 4 mmol·^–1 (v _la4), was also calculated. In the whole group, C was significantly related to height (r=–0.43;P<0.03). Neither C nor (with, in this case, the exception of the 3000 m athletes) were correlated to . On the other hand,v _{a max} was significantly correlated to over distances longer than 800 m. These were also correlated tov _la4. Howeverv _la4 occurred at 87.5% SD 3.3% ofv _{a max}, this relationship was interpreted as being an expression of the correlation betweenv _{a max} and . Calculation ofv _{a max} provided a useful means of analysing the performances. At the level of achievement studied, sustained over 3000 m corresponded tov _{a max}. The shape of the relationship ofv/v _{a max} as a function of the duration of the event raised the question of a possible change in C as a function of v during middle-distance running competitions.     

Oxygen uptake during running as related to body mass in circumpubertal boys: a longitudinal study

Summary To investigate the effect of endurance training on physiological characteristics during circumpubertal growth, eight young runners (mean starting age 12 years) were studied every 6 months for 8 years. Four other boys served as untrained controls. Oxygen uptake ( O ₂) and blood lactate concentrations were measured during submaximal and maximal treadmill running. The data were aligned with each individual's age of peak height velocity. The maximal oxygen uptake ( O _2max; ml · kg^–1 · min^–1) decreased with growth in the untrained group but remained almost constant in the training group. The oxygen cost of running at 15 km · h^–1 ( O ₂₁₅, ml · kg^–1 · min^–1) was persistently lower in the trained group but decreased similarly with age in both groups. The development of O _2max and O ₂₁₅ (1 · min^–1) was related to each individual's increase in body mass so that power functions were obtained. The mean body mass scaling factor was 0.78 (SEM 0.07) and 1.01 (SEM 0.04) for O _2max and 0.75 (SEM 0.09) and 0.75 (SEM 0.02) for O ₂₁₅ in the untrained and trained groups, respectively. Therefore, expressed as ml · kg^–0.75 · min^–1, O ₂₁₅ was unchanged in both groups and O _2max increased only in the trained group. The running velocity corresponding to 4 mmol · 1^–1 of blood lactate ( _la4) increased only in the trained group. Blood lactate concentration at exhaustion remained constant in both groups over the years studied. In conclusion, recent and the present findings would suggest that changes in the oxygen cost of running and O _2max (ml · kg^–1 · min^–1) during growth may mainly be due to an overestimation of the body mass dependency of O ₀₂ during running. The O ₂ determined during treadmill running may be better related to kg^0.75 than to kg¹.     

Prediction of individual oxygen uptake on-step transients from frequency responses

Power-oxygen uptake ( ) frequency responses can be used to predict responses to arbitrary exercise intensity patterns. It is still an open question for which range of exercise intensities such computed response patterns yield valid predictions. In the present study, we determined the power- frequency response of nine sports students by means of pseudo-randomised switching between 20 W and 80 W during upright and supine cycle exercise. Starting from a baseline of 20 W each subject also performed sustained step increases to 40 W, 80 W, 120 W, and 160 W in both positions. The individual step responses were then compared with the expected time-courses predicted on the basis of the individual frequency responses. The comparison showed a close agreement for the 20 W–40 W and 20 W–80 W steps in both positions. With larger step amplitudes the kinetics became increasingly slower than the predicted time course in both positions. During additional ramp tests (10 W · 30 s^–1) whole blood lactic acid concentration [1a^–]_b tended to be higher in the supine position at exercise intensities higher than 160 W. The mean power at 4 mmol · 1^–1 [la^–]_b amounted to 234 (SD 32) W and 253 (SD 44) W (P<5%) in the supine and the upright position, respectively. The maximal oxygen uptake relative to body mass was not found to be significantly different [upright, mean 57 (SD 10) ml · (min · kg)^–1;supine, mean 54 (SD 10) ml · (min · kg)]. These findings would suggest that for a range of mild exercise intensities kinetics are not appreciably influenced by the step amplitude or by cardiovascular changes associated with the upright and the supine position.     

Relationship between muscle fatigue and oxygen uptake during cycle ergometer exercise with different ramp slope increments

Summary The surface electromyogram (EMG) from active muscle and oxygen uptake ( ) were studied simultaneously to examine changes of motor unit (MU) activity during exercise tests with different ramp increments. Six male subjects performed four exhausting cycle exercises with different ramp slopes of 10, 20, 30 and 40 W · min^–1 on different days. The EMG signals taken from the vastus lateralis muscle were stored on a digital data recorder and converted to obtain the integrated EMG (iEMG). The was measured, with 20-s intervals, by the mixing chamber method. A non-linear increase in iEMG against work load was observed for each exercise in all subjects. The break point of the linear relationship of iEMG was determined by the crossing point of the two regression lines (iEMG_bp). Significant differences were obtained in the exercise intensities corresponding to maximal oxygen uptake ( ) and the iEMG_bp between 10 and 30, and 10 and 40 W · min –1 ramp exercises (P < 0.05). However, no significant differences were obtained in and corresponding to the iEMG_bp during the four ramp exercises. With respect to the relationship between and exercise intensity during the ramp increments, the -exercise intensity slope showed significant differences only for the upper half (i.e. above iEMG_bp). These results demonstrated that the and at which a nonlinear increase in iEMG was observed were not varied by the change of ramp slopes but by the exercise intensity corresponding to and the iEMG_bp was varied by the change of ramp slopes. In addition, the significant differences in the exercise intensity slopes for the upper half of the tests would suggest that the recruitment patterns of MU and/or muscle metabolic state might be considerably altered depending upon the ramp slope increments.     

How should body heat storage be determined in humans: by thermometry or calorimetry?

Summary The aim of this study was to determine whether in humans there are differences in the heat storage calculated by partitional calorimetry (S, the balance of heat gains and heat losses) compared to the heat storage obtained by conventional methods (thermometry) via either core temperature or mean body temperatures ( , whereT _c is core temperature and is mean skin temperature) when two different sites are used as an index ofT _c [rectal (T _re) and auditory canal (T _ac) temperatures]. Since women respond to the heat differently than men, both sexes were studied. After a stabilisation period at thermal neutrality, six men and seven women were exposed to a globe temperature of 50°C, relative humidity of 17% and wind speed of 0.8–1.0 m·s^–1 for 90 min semi-nude at rest, whereT _re,T _ac, , metabolic rate, dry (radiant+convective heat exchange) and evaporative heat losses,S, heat storage byT _c ( ) and heat storage by were assessed every minute. In the men,S was equal to 350.8(SEM 49.6) kJ whereas amounted to only 114.6(SEM 16.2) and 196.7(SEM 32.3) kJ forT _re andT _ac, respectively (P<0.05). Final underestimatedS by 49% [177.7(SEM 23.0) kJ;P<0.05] whereas was not significantly different than S [255.7(SEM 37.9) kJ]. In the women,S corresponded to a total of 294.3(SEM 23.2) kJ, a value that was very similar to the 262.6(SEM 31.0) kJ], whereas underpredicted by 35% [190.4(SEM 26.3) kJ;P<0.05]. As in the men,S _{T c} was much lower thanS [116.6(SEM 19.9) and 190.3(SEM 24.2) kJ forT _re andT _ac, respectively;P<0.05]. Using seven other well-known weighting coefficients, could under- and overestimateS by up to 55% and 11%, respectively. In all subjects, a large portion of the variance (68% and 75%) in the difference betweenS and , could be explained primarily by the T _ac. The results demonstrated that although some estimates of thermometric heat storage matched the calorimetricS, other predictions underestimated it by up to 67% during passive heating. It is suggested that these differences can be explained in part by he site chosen to representT _c, the use of eitherT _c or in the heat storage calculation, and the thermoneutral/hot weighting coefficient(s) chosen to determine . Until more representative measurements of body temperatures at different depths (core, shell and intermediate) are possible, the use of and -derived heat storage is difficult to justify.     

Severe hypoxia decreases oxygen uptake relative to intensity during submaximal graded exercise

Summary The effect of severe acute hypoxia (fractional concentration of inspired oxygen equalled 0.104) was studied in nine male subjects performing an incremental exercise test. For power outputs over 125 W, all the subjects in a state of hypoxia showed a decrease in oxygen consumption ( O₂) relative to exercise intensity compared with normoxia (P < 0.05). This would suggest an increased anaerobic metabolism as an energy source during hypoxic exercise. During submaximal exercise, for a given O₂, higher blood lactate concentrations were found in hypoxia than in normoxia (P < 0.05). In consequence, the onset of blood lactate accumulation (OBLA) was shifted to a lower O₂ ( O₂ 1.77 l·min^–1 in hypoxia vs 3.10 l·min^–1 in normoxia). Lactate concentration increases relative to minute ventilation ( _E) responses were significantly higher during hypoxia than in normoxia (P < 0.05). At OBLA, _E during hypoxia was 25% lower than in the normoxic test. This study would suggest that in hypoxia subjects are able to use an increased anaerobic metabolism to maintain exercise performance.     

Physical work capacity in dynamic exercise with differing muscle masses in healthy young and older men

Ten young (aged 23–30 years) and nine older (aged 54–59 years) healthy men with similar estimated limb muscle volumes performed, in random order, three different types of ergometer exercise tests (one-arm cranking, two-arm cranking, and two-leg cycling) up to the maximal level. Values for work load (WL), peak oxygen consumption , peak heart rate (HR), peak ventilation , respiratory gas exchange ratio (R), recovery blood lactate concentration [La^–], and rating of perceived exertion (RPE) were compared between the age-groups in the given exercise modes. No significant age-related differences in WL, peak , peak HR, R, [La^–], or RPE were found in one-arm or two-arm cranking. During one-arm cranking the mean peak was 1.65 (SD 0.26)1 · min^–1 among the young men and 1.63 (SD 0.10)1 · min^–1 among the older men. Corresponding mean peak during two-arm cranking was 2.19 (SD 0.32)1 · min-1 and 2.09 (SD 0.18)1 · min^–1, respectively. During one-arm cranking peak was higher (P < 0.05) among the older men compared to the young men. During two-leg cycling the young men showed higher values in WL (P < 0.001), peak (P < 0.001), and peak HR (P < 0.001). The mean peak was 3.54 (SD 0.24)1 · min^–1 among the young men and 3.02 (SD 0.20)1 · min^–1 among the older men. Corresponding mean peak HR was 182 (SD 5) beats · min^–1 and 170 (SD 8) beats · min^–1, respectively. During two-leg cycling, peak , R, [La^–], and RPE did not differ between the two age-groups. In summary, the older men with similar sizes of estimated arm and leg muscle volumes as the young men had a reduced physical work capacity in two-leg cycling. In one-arm or two-arm cranking, no significant difference in work capacity was found between the age-groups. These results indicate, that in healthy men, age, at least up to the 6th decade of life, is not necessarily associated with a decline in physical work capacity in exercises using relatively small muscle groups, in which the limiting factors are more peripheral than central.     

Effect of previous supramaximal work on lacticaemia during supra-anaerobic threshold exercise

Summary Twelve male and female subjects (eight trained, four untrained) exercised for 30 min on a treadmill at an intensity of maximal O₂ consumption (% O_2max) 90.0%, SD 4.7 greater than the anaerobic threshold of 4 mmol ·1^–1 (Th_an =83.6% O_2max, SD 8.9). Time-dependent changes in blood lactate concentration ([la_b]) during exercise occurred in two phases: the oxygen uptake ( O₂) transient phase (from 0 to 4 min) and the O₂ steady-state phase (4–30 min). During the transient phase, [la_b] increased markedly (l.30 mmol · l ^–1 · min ^–1, SD 0.13). During the steady-state phase, [la_b] increased slightly (0.02 mmol · 1^–1 · min^–1, SD 0.06) and when individual values were considered, it was seen that there were no time-dependent increases in [la_b] in half of the subjects. Following hyperlacticaemia (8.8 mmol -l^–1, SD 2.0) induced by a previous 2 min of supramaximal exercise (120% O_2max), [la_b] decreased during the O₂ transient (–0.118 mmol · 1^–1 · min^–1, SD 0.209) and steady-state (–0.088 mmol · 1^–1 · min ^–1, SD 0.103) phases of 30 min exercise (91.4% O_2max, SD 4.8). In conclusion, it was not possible from the Th_an to determine the maximal [la_b] steady state for each subject. In addition, lactate accumulated during previous supramaximal exercise was eliminated during the O₂ transient phase of exercise performed at an intensity above the Th_an. This effect is probably largely explained by the reduction in oxygen deficit during the transient phase. Under these conditions, the time-course of changes in [la_b] during the O₂ steady state was also affected.     

Submaximal working capacity,heart size and body size in boys 8–18 years

Heart diameters, heart volume (HV), PWC ₁₃₀, O₂ at 130 heart rate, and cardiorespiratory reactions during work at 3 kgm·s^–1 were obtained in 237 boys ranging in age from 8–18 years. Results indicate that heart size, PWC ₁₃₀, O₁₃₀, and exercise HR, O₂/HR, and SBP change significantly with age. On the other hand, HV·kg^–1 and work O₂, _E and _E/ O₂ remain rather stable throughout the growth period.Correlation analysis indicates that about 85% of the observed variation in the size of the heart during growth can be accounted for by body weight, while about 70% of the variation in light submaximal working capacity ( O₁₃₀) can be explained by HV alone. Holding age, height and body weight constant by partial correlation procedures yields significant relationships between HV and O₁₃₀ (r = 0.461), and between HV·kg^–1 and O₁₃₀ (r = 0.414). Age, height, weight and size of the heart correlated simultaneously against O₁₃₀ account for 75% of the variance in the dependent variable.It would seem important to suggest the need for study of the interactions between age, size and maturity, in addition to indicators of size and efficiency of the oxygen delivery system, and indices of muscle oxygen utilization efficiency. Such an approach will permit a more definite partitioning of the variance in submaximal aerobic capacity during growth, and would probably yield a more conservative estimate of the relationship between the size of the heart and submaximal working capacity during growth.Abbreviations used HV heart volume - HV·kg^–1 heart volume per kg of body weight - PWC ₁₃₀ physical working capacity in kgm·s^–1 of work at a heart rate of 130·min^–1 - O₁₃₀ oxygen consumption per min at a heart rate of 130·min^–1 - O₂, , _E, _E/ O₂, HR, O₂/HR, SBP oxygen consumption, breathing frequency, expiratory volume, respiratory equivalent, heart rate, oxygen pulse, systolic blood pressure in the third minute of work at 3 kgm·s^–1 - CA chronological age Partially supported by grants from the Kuratorium für die Sportmedizinische Forschung, Federal Republic of Germany and Laval University, Quebec, Canada     

Time of day effects on sympathoadrenal and pressor reactivity to exercise in healthy men

Summary To investigate the influence of time of day on sympathoadrenal and pressor reactivity during exercise, eight trained men [age, mean (SD), 24 (0.5) years; maximal oxygen uptake ( ), 4.7 l·min^–1] performed bouts of static (ST) and dynamic (DYN) exercise at 0600–0800 hours (AM) and at 1600–1800 hours (PM). The ST protocol utilized a two-leg isometric contraction at 30% maximum voluntary contraction until failure, and was monitored by a strain gauge interfaced from a leg extension apparatus to a computer. Heart rate (f_c) and blood pressure ( ) responses were recorded at rest, after 1 and 2 min of exercise, and at failure. Epinephrine (EPI) and norepinephrine (NE) levels were recorded before exercise, and after 2 min of exercise. The DYN exercise protocol involved stationary. cycling for consecutive 6-min periods at 60% and 80% . f_c, , EPI, and NE were recorded before exercise and at each workload. No differences were observed in preexercise or exercise f_c under any condition. Preexercise did not differ under any condition. The response to DYN was significantly higher at 80% during PM only. was significantly higher in ST-PM at 1 min, 2 min, and failure. Elevations in both systolic and diastolic P _a contributed to this difference. Preexercise EPI-ST-AM was significantly elevated vs PM, but no other preexercise data were significantly different. Absolute exercise levels were significantly higher for EPIST-PM vs AM only, but the percentage change from baseline was significantly (P<0.01) higher in ST-PM for EPI (+231% PM vs + 32% AM) and NE (+352% PM vs +216% AM). The EPI and NE responses to DYN exercise tended to be higher in AM, but were not significantly different. These data support a time of day pattern in sympathoadrenal and pressor reactivity to exercise that is dependent on the type of activity involved but independent of baseline patterns.     

Cardiac output in paraplegic subjects at high exercise intensities

Summary The purpose of this investigation was to compare cardiac output ( _c ) in paraplegic subjects (P) with wheelchair-confined control subjects (C) at high intensities of arm exercise. At low and moderate exercise intensity _c was the same at a given oxygen uptake ( O₂) in P and C. A group of 11 athletic male P with complete spinal-cord lesions between T6 and T12 and a group of 5 well-matched athletic male C performed maximal arm-cranking exercise and submaximal exercise at 50%, 70% and 80% of each individual's maximal power output (W_max) . Maximal O₂ ( O_2max) was significantly lower, O_2max per kilogram body mass was equal and maximal heart rate (f _c) was significantly higher in P compared to C. At O₂ of 1.3, 1.5 and 1.7 1-min^–1, and for P 65%–90% of the O_2max, _c was not significantly different between the groups, although, _c in P was achieved with a significantly lower stroke volume (SV) and a significantly higherf _c. Although the SV was lower in P, it followed the same pattern as SV in C during incremental exercise, i.e. an increase in SV until about 45%W _max and thereafter a stable SV. The similar _c at a given O₂ in both groups indicated that, even at high exercise intensities, circulation in P can be considered isokinetic with a complete compensation byf _c for a lower SV.