大学生蠕形螨感染情况调查

目的:了解在校大学生蠕形螨感染情况,探讨蠕形螨感染与面部皮肤疾病的关系.方法:采用透明胶带粘贴法对638名在校大学生进行蠕形螨检查,同时对面部皮肤状况进行调查.结果:在校大学生蠕形螨感染率为17.55%,且男性(22.05%)显著高于女性(14.58%);毛囊蠕形螨面部感染率(65.18%)高于皮脂蠕形螨(24.11%);有面部皮肤疾病者蠕形螨感染率明显高于面部皮肤正常者.结论:本校大学生蠕形螨感染较为普遍,感染多为毛囊蠕形螨;蠕形螨感染是痤疮、酒渣鼻等皮肤疾病的致病因素之一.     

1037名在校大学生蠕形螨感染的调查

目的了解本地大学生蠕形螨感染状况,探讨蠕形螨感染与皮肤疾病的关系。方法采用透明胶带法对1037名在校大学生进行蠕形螨感染检查,同时观察其面部皮肤状况,询问与调查相关情况并记录于调查表内。结果本地大学生蠕形螨感染率为53.81%,其中男生感染率56.50%,女生感染率51.95%,两者之间差异无显著性(P>0.05);二年级、三年级、四年级学生感染率均大于一年级(P<0.01);面部有痤疮者、有脂溢性皮炎者、有毛囊炎或毛囊扩张者感染率均大于面部皮肤正常者(P<0.05);常混用他人日常用品者感染率大于不常混用他人日常用品者(P<0.05)。结论本地大学生蠕形螨感染较为普遍;蠕形螨感染可能是痤疮、脂溢性皮炎、毛囊炎等皮肤疾病的致病因素之一;通过日常用品间接感染可能是蠕形螨感染中一种重要方式。     

新乡医学院在校大学生蠕形螨感染状况调查

目的了解新乡医学院在校大学生蠕形螨的感染情况,研究蠕形螨感染与面部皮肤损害的关系。方法透明胶纸法对部分在校学生进行抽样调查。结果蠕形螨总感染率27.27%,男、女生感染率分别为35.29%和23.68%,二者差别有统计学意义(P<0.05);单纯毛囊蠕形螨构成比64.44%,单纯皮脂蠕形螨构成比20.00%,二者差别有统计学意义(P<0.01);面部有皮肤疾患的学生中蠕形螨感染率为65.22%,皮肤无明显皮损学生中蠕形螨感染率为12.61%,二者差别有统计学意义(P<0.01)。结论新乡医学院在校大学生蠕形螨感染率低,但仍应加强对大学生进行相关预防知识的普及教育,使学生养成良好的生活卫生习惯。     

阜阳市某高职大学生蠕形螨感染情况调查

目的了解安徽省阜阳职业技术学院在校大学生蠕形螨感染情况,分析蠕形螨感染的影响因素。方法以安徽省阜阳职业技术学院大一、大二学生为研究对象,采用随机抽样的方法 ,对442名在校高职大学生通过透明胶纸粘贴法进行蠕形螨检查,同时对调查对象的个人习惯、洁面方式、皮肤类型、面部疾患等方面进行问卷调查。结果以阜阳市某职业技术学院442名在校大学生为调查对象,蠕形螨感染者为86人,总感染率为19.46%(86/442),单纯毛囊蠕形螨感染占82.56%(71/86),高于单纯皮脂蠕形螨感染及混合感染;面颊部位感染率23.26%(20/86)较鼻部感染率高;面部有疾患者如痤疮、皮炎、毛囊炎等感染率25.70%(55/214),高于面部正常者;油性皮肤学生感染率为27.94%(38/136),高于混合性皮肤及干性皮肤学生;在调查季节方面夏季感染率为26.57%(38/143),高于冬季感染率;在感染程度方面,轻度面部蠕形螨感染率高达82.56%,经χ2检验分析,显示季节、皮肤类型、面部疾患为蠕形螨感染的影响因素,多因素非条件logistic回归分析,面部疾患为蠕形螨感染的危险因素。结论安徽省阜阳职业技术学院大学生蠕形螨感染较为普遍,以毛囊蠕形螨感染为主,多为轻度感染,男女生蠕形螨感染率无显著差异,其感染率与皮肤性质、面部疾患、季节温度有关。     

邢台市某医学院校新生干性皮肤者面部蠕形螨感染调查

目的调查该医学院新生干性皮肤者面部人体蠕形螨的感染情况,并分析人体蠕形螨感染的影响因素,为特定人群蠕形螨的防治提供依据。方法对部分新生进行问卷调查,并对干性皮肤者面部蠕形螨的感染进行调查,采用透明胶带粘贴过夜法查螨虫。胶带置于光镜下检查,阳性片计数虫数并进行虫种鉴定。结果共调查804名学生,其中干性皮肤者108名,占13.4%。干性皮肤者面部蠕形螨感染情况如下,感染率为22.2%(24/108),单纯毛囊蠕形螨感染占66.7%(16/24),单纯皮脂蠕形螨感染占16.7%(4/24),二者差异显著有统计学意义(x2=21.0,P0.01),混合感染占16.7%(4/24)。轻度感染占100%。鼻侧感染58.3%(14/24)较额部41.7%(10/24)、鼻尖为0,前二者与鼻尖差异有统计学意义(x2=7.61,P0.01)。结论该校新生干性皮肤者人体蠕形螨普遍,但均为轻度感染,毛囊蠕形螨感染高于皮脂蠕形螨,感染以鼻侧、额部为主,感染与生活习惯有关。     

浙江嵊县新建村人体蠕形螨流行情况调查

在浙江嵊县新建村,对353人(男179人,女174人;年龄3～81岁)作了人体蠕形螨的流行情况调查。检出蠕形螨阳性者144人,感染率约41％。男女感染率无显著差别;但感染率随年龄的增加而上升。在144例阳性者中,单纯感染毛囊蠕形螨或皮脂蠕形螨者分别为84人(约58％)和34人(约24％),混合感染者26人(约18％)。经统计分析,毛囊蠕形螨的感染率和感染严重度均明显高于皮脂蠕形螨。这两种蠕形螨的感染率和感染严重度在男女性别间无明显差别。本文还对蠕形螨的传播途径及致病性进行了讨论。     

1037名医学生蠕形螨感染情况调查

目的：了解本校大学生蠕形螨感染状况，探讨蠕形螨感染与皮肤疾病的关系。方法：采用透明胶带法对1037名在校大学生进行蠕形螨感染检查，同时观察其面部皮肤状况、询问与调查相关情况记录于调查表内。结果：本校大学生蠕形螨感染率为53．81％，其中男生感染率56.50％，女生感染率51．95％，两者之间差异无显著性(P＞0．05)；二年级、三年级、四年级学生感染率均大于一年级(P＜0．01)；面部有痤疮者、有脂溢性皮炎者、有毛囊炎或毛囊扩张者感染率均大于面部皮肤正常者(P＜0．05)；常混用他人日常用品者感染率大于不常混用他人日常用品者(P＜0．05)。结论：本校区大学生蠕形螨感染较为普遍；蠕形螨感染是痤疮、脂溢性皮炎、毛囊炎等皮肤疾病的致病因素之一；通过日常用品间接感染是蠕形螨感染中一种重要的感染方式o     

新疆某部战士人体蠕形螨感染状况调查及相关因素分析

目的调查新疆某部战士人体蠕形螨感染情况并分析相关因素。方法采用透明胶纸粘贴法对335名部队战士开展蠕形螨的感染检查,并对家庭背景、个人卫生习惯及面部皮肤类型、疾患作问卷调查分析。结果蠕形螨总感染率为25.37%,混用日常洗浴用品者、面部清洁次数少且有面部皮肤疾患者及入伍时间长的患者感染率明显高于同类对比组,各组间差异有统计学意义(P<0.05)。感染主要以毛囊蠕形螨为主,毛囊蠕形螨和皮脂蠕形螨的感染率构成比分别是76.47%和15.29%,二者差异有统计学意义(P<0.0 001)。不同年龄段及不同地域、城乡间战士的感染率差异无统计学意义(P>0.05)。结论蠕形螨感染在部队战士群体中较普遍,主要与集体生活环境、入伍时间长短、个人卫生习惯、面部皮肤类型及疾患等因素有密切关系,应加强相关预防知识的宣传教育,培养良好的个人卫生习惯。     

泉州地区高职医学院校大学生蠕形螨感染情况调查

目的了解泉州地区某高职医学院校大学生蠕形螨感染情况,分析与蠕形螨感染相关的影响因素,为预防蠕形螨感染提供重要依据。方法采用透明胶纸法对某高职医学院校2018级医学检验技术、公共卫生管理等不同专业学生进行面部蠕形螨检测,同时对性别、皮肤类型、洁面次数等进行问卷调查,分析感染影响因素。结果大学生受检者271人,蠕形螨阳性107人,总感染率为39.48%(107/271),其中男、女生感染率分别为50.00%(27/54)和36.87%(80/217)。单纯毛囊蠕形螨感染率(57.94%)高于单纯皮脂蠕形螨感染率(30.84%)和混合虫体感染率(11.21%)。阳性感染者轻、中度感染率分别为88.79%、11.21%,重度感染者未见。皮肤类型(χ~2=6.292,P0.05)、皮损情况(χ~2=41.119,P0.05)、洁面次数(χ~2=8.439,P0.05)、宿舍卫生打扫频率(χ~2=26.315,P0.05)、宿舍毛巾摆放情况(χ~2=6.305,P0.05)和宿舍潮湿(χ~2=14.059,P0.05)等影响因素差异均有统计学意义。结论泉州地区某高职医学院校大学生蠕形螨感染情况较为普遍,感染率与皮肤状况、个人卫生习惯和宿舍集体生活有密切关系,需加大对蠕形螨的知识宣传和预防力度。     

广州部分医科大学生蠕形螨感染的调查

目的 :调查近年广州医科大学生人体蠕形螨的感染情况。方法 :采用透明胶纸粘贴法 ,剪取 2cm× 5cm透明胶纸 ,嘱受检者于临睡前紧贴于鼻唇沟皮肤上 ,次晨取下平贴于干净载玻片上 ,由专人光镜检查 ,对阳性片鉴定虫种并计算虫数。结果 :调查 18～ 2 1岁学生 6 0 2人 ,其中男生 331人 ,女生 2 71人。检出人体蠕形螨者 14 4人 ,感染率 2 3.92 %。男学生感染率为 2 4 .4 7% (81/331人 ) ,女学生为 2 3.2 5 % (6 3/2 71人 ) ,两者差异无显著性 (P >0 .0 5 )。从学生来源地看 ,城镇学生感染率为 2 1 31% (78/36 6人 ) ,农村学生为 2 7 97% (6 6 /2 36人 ) ,两者差异无显著性 (P>0 .0 5 )。感染者的感染度以每条透明胶纸 1～ 5条虫为多 ,占 89.5 8% (12 9/14 4人 ) ,检获的螨大多为毛囊蠕形螨占 95 .83% (138/14 4人 ) ,单一感染皮脂蠕形螨仅 0 .6 9% (1/14 4人 ) ,两者混合感染为 3.4 7% (5 /14 4人 )。结论 :广州部分医学生人体蠕形螨感染率较高 ,感染大多为毛囊蠕形螨 ,少数为皮脂蠕形螨及两者混合感染 ,两种蠕形螨的感染度都属轻度     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.