前交叉韧带重建术中胫骨骨道定位的应用解剖研究

[目的]探究前交叉韧带(anterior cruciate ligament,ACL)于胫骨止点处的解剖形态以及测量髁间窝顶线与胫骨平台交汇点至后交叉韧带前缘的距离对胫骨骨道定位的解剖学意义,为ACL重建术提供理论依据。[方法]选取新鲜成人膝关节标本8例,仔细剔除关节周围肌肉、后关节囊等结构,保留前后交叉韧带及两侧侧副韧带,保证膝关节正常屈伸范围。在屈伸膝关节时按照ACL纤维张力区将其分为前内束和后外束,在胫骨附着处将ACL切断制备ACL损伤模型。用测量工具和Phontoshop软件获取ACL基本解剖参数以及髁间窝顶线与胫骨平台的交汇点、ACL前缘、ACL胫骨止点的中心点分别至后交叉韧带前缘的距离。[结果]ACL平均体部直径为(11.21±0.76)mm,ACL在胫骨止点处的平均最大横径为(11.34±0.79)mm,平均最大前后径为(16.54±0.82)mm。前内束和后外束在胫骨止点处的平均面积分别为(113.35±29.65)mm~2和(83.29±16.99)mm~2。髁间窝顶线与胫骨平台的交汇点、ACL前缘以及ACL胫骨止点的中心点至后交叉韧带前缘的距离分别为(12.13±0.96)mm,(21.14±0.83)mm和(8.82±0.77)mm。[结论]利用胫骨平台骨道定位ACL在股骨的解剖止点现实可行,在ACL重建术中具有重要意义。     

前交叉韧带重建术中隧道定位对移植物等距特性影响的研究

目的探讨前交义韧带(ACL)重建术中股骨和胫骨隧道定位变化对移植物等距特性的影响。方法选用10具正常新鲜冷冻尸体膝关节标本,在股骨取3个定位点,第一个定位点位于右膝11点(左膝1点)过顶点前方5～6 mm处,作为前束点；第二点位于前束点前5 mm处,作为误差点；第三点位于屈膝90°时,ACL附着区长轴与经股骨-胫骨接触点的垂直线的交点,作为后束点。在ACL胫骨附着区的前后径上取3个定位点,一个位于原ACL附着区中心,称为中心点；一个位于中心点后5 mm处,称为5 mm后点；一个位于中心点后10 mm处,称为10 mm后点。模拟ACL重建步骤,经各个股骨和胫骨定位点分别钻直径为2 mm的骨隧道,通过测量钢丝和等距测量仪来检测膝关节屈曲过程中各个股骨隧道内口相对于各个胫骨隧道内口的距离变化。结果相对于某一个固定的股骨隧道内口,胫骨隧道内口的前后移位变化对移植物等距特性的影响差异无显著性意义(P＞0．05)；相对于某一个固定的胫骨隧道内口,股骨隧道内口位置的变化对移植物等距特性的影响差异有极显著性意义(P＜0．01)。从膝关节完全伸直到极度屈曲的过程中,如果股骨隧道内口选择在前束点,则两内口间移植物长度变化在生理等距范围内；若选择在误差点,则两内口间移植物长度变化表现为超出生理等距范围的延长；若选择在后束点,则两内口间移植物长度变化表现为超出生理等距范围的短缩。结论ACL重建时,胫骨隧道内口在ACL附着区中心与棘间区后缘之间的前后移位对移植物等距特性无明显影响,股骨隧道内口的移位对移植物的等距特性有明显影响。     

膝关节半月板根部附着区的解剖学测量

目的:测量国人膝关节内外侧半月板前后根部附着区的解剖学数据,为临床修复半月板根部损伤提供解剖学基础。方法:选取30个国人成人尸体膝关节标本,其中男16例,女14例;死亡年龄35～68(55.6±7.8)岁。对半月板根部附着区结构进行解剖,测量内外侧半月板根部附着区中心点与胫骨内外侧髁间棘、后交叉韧带前缘、内侧胫骨平台软骨后方外侧缘及外侧胫骨平台软骨后方内侧缘等标志点的位置关系和各个附着区的面积。结果:内侧半月板后根部附着区:中心点位于胫骨内侧髁间棘后方(11.73±3.10) mm、外侧(2.77±0.86) mm,后交叉韧带前缘前(2.76±0.76) mm,内侧平台软骨外侧缘外(3.92±0.22) mm,附着区面积(31.29±5.18) mm~2。内侧半月板前根部附着区:中心点位于胫骨内侧髁间棘前方(25.40±5.27) mm、外侧(3.01±0.86) mm,附着区面积(46.18±11.60) mm~2。外侧半月板后根部附着区:中心点位于胫骨外侧髁间棘后方(4.51±1.35)mm、内侧(1.85±0.34) mm,后交叉韧带前缘前(6.91±1.11) mm,外侧平台软骨内侧缘内(3.16±0.96) mm,附着区面积(44.10±6.23) mm~2。外侧半月板前根部附着区:中心点位于胫骨外侧髁间棘前方(12.97±2.92) mm、外侧(1.31±0.22) mm,附着区面积(60.84±14.98) mm~2。结论 :该试验定量描述内外侧半月板前后根部附着区的面积以及其中心点与相应标志点的位置关系,为临床修复半月板根部损伤提供一定的解剖学参考。     

前交叉韧带胫骨附着处解剖学观察

目的观察前交叉韧带(ACL)胫骨附着处的解剖学形态,并对学术界存在的一些相关问题进行探讨。方法测量中国人干燥骨骼标本ACL胫骨附着处的大小、形态、位置。结果最大横径(9.38±1.67)mm;最大纵径(15.93±2.52)mm;附着区前缘距胫骨平台前缘的距离(7.85±1.52)mm;胫骨平台附着区长轴与胫骨平台平面正中矢状轴夹角(21.54±4.61)°;ACL的胫骨附着区形态主要以前宽后窄的倒三角形偏心形态为主(57.4%)。结论ACL胫骨附着处的特殊解剖位置有利于ACL在剧烈运动中具备较强的抗撕脱能力,另一方面亦导致了一旦ACL撕裂,往往会增加合并半月板损伤的发生率;A-CL纤维在胫骨附着处的不规则偏心分布形态为膝关节镜下ACL重建寻找“等长点”带来困难。     

股骨Blumensaat线的MRI测量及其对重建ACL的意义

目的应用MRI对股骨Blumensaat线的测量,为重建前交叉韧带(anterior cruciate ligament,ACL)提供参考。方法通过选择100例正常的膝关节伸直位磁共振检查结果,在适当的切面上绘制Blumensaat线延长线与胫骨平台的交点,测量其在胫骨矢状径位置及其与后交叉韧带(posterior cruciate ligament,PCL)的距离,并与ACL胫骨侧生理止点中心和PCL的距离比较。结果 Blumensaat线延长线与胫骨平台的交点在胫骨矢状径上距前缘(51.9±7.3)%,与PCL距离(14.2±2.5)mm,较ACL生理止点中心靠后。结论为避免髁间窝前方撞击,重建ACL胫骨侧止点定位于胫骨平台生理性止点中心后方或PCL前方8～10mm,个别人需更后方。     

关节镜下胫骨髁间棘骨折的治疗进展

髁间棘是胫骨平台中间的一条不规则的隆起,是前交叉韧带(ACL)下止点的附着部.髁间棘撕脱骨折上移明显时,顶挤髁间出现顶部撞击,除影响膝关节伸直外,由于前交叉韧带松驰,会出现前交叉韧带缺失的症状,表现为膝关节前向不稳[1].因此,对有移位的髁间棘撕脱骨折应采取手术治疗,复位骨折并要进行很好的固定.     

前内侧入路解剖重建单束前交叉韧带的临床评估

目的评估关节镜下经前内侧入路解剖重建单束前交叉韧带(ACL)的位置、形态及临床效果。方法对25例ACL断裂患者在关节镜下经前内侧入路应用解剖重建技术行单束ACL重建术,移植物应用自体腘绳肌腱。术后行X线、MRI检查,了解骨道情况,观察移植物形态及张力,并与11例健侧膝关节的正常ACL进行对比。应用Lysholm评分系统评估膝关节功能。结果术后X线片显示股骨隧道内口位于髁间窝顶与股骨后缘皮质线交叉点前缘,胫骨隧道内口位于髁间窝顶后方。MRI显示所有重建ACL张力良好,ACL上倾角为50.82°±4.57°,胫骨平台止点至前缘距离与平台纵径比值为0.50±0.04,两项与对照组比较差异均无统计学意义(P0.05)。患者均获得随访,时间为13~44个月。Lysholm评分术后为92.20分±4.29分,明显高于术前的64.76分±7.16分(P0.01)。结论关节镜下经前内侧入路解剖重建ACL的位置及形态接近解剖结构,早中期临床效果满意。     

膝关节前交叉韧带胫骨止点的软组织解剖标记

背景：膝关节前交叉韧带（ACL）重建时,胫骨骨道定位不准会产生重建韧带与髁间窝的撞击或起不到维持膝关节稳定性的作用。因此,确定ACL胫骨止点的位置非常重要。目的：研究膝关节ACL胫骨止点前内束（AMB）和后外束（PLB）与软组织标记后交叉韧带（PCL）和外侧半月板前角的距离,从而明确ACL胫骨止点在胫骨平台的位置,为ACL损伤双束重建提供理论支持。方法：解剖18个膝关节尸体标本（左膝10个,右膝8个）,测量ACL中点、AMB中点、PLB中点与PCL和外侧半月板前角的距离,并分析左、右膝关节是否存在差异。结果：AMB中点与PCL和外侧半月板前角的距离分别为（15.00±3.97）mm和（19.78±4.10）mm;PLB中点与两者的距离分别为（10.17±5.56）mm和（19.50±4.40）mm;ACL中点与两者的距离分别为（12.67±4.52）mm和（19.61±3.87）mm。左右膝关节ACL中点、AMB中点、PLB中点与软组织解剖标记的距离无明显统计学差异。结论：膝关节ACL损伤行手术重建时,可采用PCL和外侧半月板前角作为定位标记。     

膝关节镜下单隧道Orthocord缝线联合外排铆钉固定治疗胫骨髁间棘骨折

目的 探讨膝关节镜下胫骨单隧道Orthocord缝线联合外排铆钉固定治疗胫骨髁间棘骨折的临床疗效.方法 2018年1月～2020年7月我们采用膝关节镜下胫骨单隧道Orthocord缝线联合外排铆钉固定治疗胫骨髁间棘骨折,借鉴前交叉韧带(anterior cruciate ligament,ACL)重建时胫骨端隧道收紧固...     

同种异体半月板移植的研究现状

1 研究背景 1.1半月板的解剖与功能 半月板是膝关节内的软骨盘,位于胫骨平台与股骨髁之间,内侧为C型,外侧为近似O型.均分为前角、后角和体部.前后角借助"止点"结构固定于胫骨平台,内侧半月板前角止于胫骨髁间前斜坡处,后角止于内侧髁间棘后侧、后交叉韧带止点之前;外侧半月板前角止于外侧髁间棘前部,部分纤维与前交叉韧带相延续,后角止于外侧髁间棘后缘.     

胸腰椎骨折椎弓根内固定断裂与植骨融合方式的相关性分析

[目的]探讨胸腰椎骨折椎弓根螺钉内固定系统内固定术后,椎弓根螺钉断裂与植骨融合方式之间的关系,以探讨胸腰椎骨折植骨融合的最佳方式。[方法]回顾性研究1995年5月~2005年12月本院脊柱外科收治的胸腰椎骨折病人197例,其中A组单纯内固定(不植骨)患者14例,B组“H”形椎板植骨21例,C组横突间植骨67例,D组椎间、椎内联合横突间植骨95例。[结果]术后随访6~32个月,内固定断裂12例,其中A组4例,B组3例,C组5例,D组0例,4组中D组内固定断裂率显著低于其他3组(P<0.05)。[结论]椎间、椎体内联合横突间植骨重建脊柱三柱的稳定性,符合人体生物力学原理,能有效降低内固定断裂的发生。     

On the measurement of the functional properties of the CFTR

A number of methods are currently employed to assess the functional properties of CFTR channels and their response to pharmacological potentiators, correction of the defective CFTR trafficking, and vectorial introduction of new proteins. Here we review the most common methods used to assess CFTR channel function. The suitability of each technique to various experimental conditions is discussed.     

Preservation of the pylorus and resection of the head of the pancreas

The historical evolution of the pylorus-preservation resection of the head of the pancreas is traced from the first resections early in this century to relative standardization of the operation, to a lowering of the operative mortality, and to an interest in improving nutritional status after resection. There are many theoretical advantages for the function of the upper gastrointestinal tract after pylorus and gastric preservation, such as maintenance of gastric capacitance and equilibration of osmotic pressure in gastric digestants, foodstuff digestion and absorption, and bowel motility. After the pylorus-preserving resection, gastric emptying is normal, pyloric function to prevent duodenal reflux is often normal, and gastric acids and serum levels of duodenal hormones are at normal levels, whereas after standard pancreatoduodenectomy, all of these are often abnormal. No prospective blinded studies have been published comparing nutritional values after the two operative procedures, but evidence is presented of a satisfactory result with regard to gastric capacitance, body weight gain, and lack of postgastrectomy symptoms. An undoubted advantage of the pylorus-preserving feature is a simplification of the operation. These gains are achieved without increase in operative mortality, without increase in the incidence of jejunal ulcer, and without theoretical or actual decrease in value of the procedure as a cancer operation, except in patients with duodenal carcinoma proximal to the ampulla of Vater.     

下颌全牙弓后移量及最后界的测量

目的：研究下颌牙弓的有效后移量及找寻下颌牙弓移动的后界。方法：选取涉及拔除下颌第三磨牙或下颌第三磨牙缺失的病例18例（男6例,女12例）。采用种植支抗牵引下牙弓向远中,治疗完成时所有病例均明确到达下颌牙弓后界,即下颌第二磨牙远中到达下颌升支前缘软组织交界处。应用治疗前后的曲断片测量下颌第二磨牙远中到升支前缘的距离。结果：下颌第二磨牙后移量为（3.49±1.21）mm;治疗后磨牙后间隙的长度为（4.43±0.97）mm。结论：下颌牙弓可确定性地实现整体后移;最大后移量由磨牙后间隙的长度决定;其最后界止于下颌第二磨牙远中与下颌升支前缘软组织交界处。     

The Measurement of the Inclination Angle of the Hamate and Analysis of the Inclination Angle for the Rotation Deformity of the Little Finger in the Fixation of the Carpometacarpal Joint

ObjectiveComplex base fractures of the fifth metacarpal bone and dislocation of the fifth carpometacarpal joint are more prone to internal rotation deformity of the little finger sequence after fixation with a transarticular plate. In the past, we have neglected that there is actually a certain angle of external rotation in the hamate surface of transarticular fixation. This study measured the inclination angle of the hamate surface relative to the fifth metacarpal surface for clinical reference.MethodsIn a prospective single‐center study, we investigated the tilt angle of 60 normal hamates. The study included thin‐layer computed tomography (CT) data from 60 patients from the orthopaedic clinic and inpatient unit from January 2017 to March 2020, including 34 men and 26 women who were 15~59 years old, average 35 years old. The CT data of 60 cases in Dicom format of the hand was input into Mimics and 3‐Matics software for three‐dimensional (3D) reconstruction and measuring the angle α between hamate surface and the fifth metacarpal surface. According to the possible placement of the transarticular plate on the fifth metacarpal surface, we measured the angle β between the hamate surface 1 and the fifth metacarpal surface and the angle γ between the hamate surface 2 and the fifth metacarpal surface.ResultsThe average angle between the hamate surface and the fifth metacarpal surface was 11.66°. The hamate surfaces 1 and 2 have an external rotation angle of 7.30° and 7.51° on average with respect to the fifth metacarpal surface, respectively. There is no statistically significant difference in the angles between the two groups (P > 0.05).ConclusionsThe horizontal angle of the dorsal side of the hamate is different from the back of the fifth metacarpal surface, and the hamate has a certain external rotation angle with respect to the fifth metacarpal surface. No matter how the transarticular plate is placed, the plate always has a certain external rotation angle relative to the fifth metacarpal surface. When the fixation is across the fifth carpometacarpal joint, if the plate does not twist and shape, it will inevitably cause internal rotation of the fifth metacarpal, resulting in internal rotation deformity of the little finger sequence.     

静脉输注甘露醇开放血脑屏障对抗生素透过血脑屏障的影响

目的　通过快速静脉输注甘露醇可逆性开放血脑屏障 (BBB) ,探知此方法能否增加抗生素透过BBB的量 ,在何时达到最高峰 ,其通透量增加后临床上有无不良反应。方法　采用自身配伍设计 ,共 6个样本组。对照组仅使用抗生素 ;其余 5组分别在使用甘露醇前 60、3 0min ,同时使用甘露醇后 3 0、60min使用抗生素 ,各组皆取使用抗生素后 1h的脑脊液测其抗生素浓度。抗生素选用头孢三嗪。结果　测量值经过q检验 ,经 2 0 %甘露醇处理前后的CSF中的头孢三嗪浓度差异有非常显著性。全组患者经临床观察未出现神经系统的不良反应。结论　经静脉快速输注2 0 %甘露醇后可以使透过BBB的水溶性抗生素的量增加 ,两者使用的顺序是在抗生素使用 3 0min内即给予甘露醇快速滴注。该方法不会增加低神经毒性抗生素在中枢神经系统的不良反应。     

Preservation of the pylorus in resection of the head of the pancreas

Whipple's pancreatoduodenectomy was the standard operation for diseases of the head of the pancreas for more than 40 years, but the results were vitiated in part by poor gastrointestinal function and malnutrition. Reintroduced in 1978, pylorus-preserving proximal pancreatoduodenectomy (PPPP) has had an increasing impact on pancreatic surgery as its benefits have been recognized: improved nutritional status, decreased incidence of postgastrectomy syndromes, and a technically easier operation. Postoperative mortality rates and 5-year survival rates are comparable with those of the classic Whipple procedure. PPPP is indicated for most patients with chronic pancreatitis of the pancreatic head. It is also appropriate for patients with periampullary cancer and for those with pancreatic cancer arising from the lower part of ‘the head and the uncinate process. More than 650 patients have now undergone PPPP: 31% for chronic pancreatitis and 66% for periampullary and pancreatic cancers. We assess the indications for PPPP, outline the operation, and review the results.