共查询到20条相似文献,搜索用时 31 毫秒
1.
Linnainmaa M Laitinen J Leskinen A Sippula O Kalliokoski P 《Journal of occupational and environmental hygiene》2008,5(1):28-35
The performance of four sampling devices for inhalable dust and three devices for respirable dust was tested with different kinds of dusts in the laboratory and in the field. The IOM sampler was chosen as the reference method for inhalable dust, and the IOM sampler provided with the porous plastic foam media was used as the reference method for respirable dust. The other tested instruments were the Button sampler, the optical Grimm aerosol monitor, and the Dekati two-stage cascade impactor with cutoff sizes of 10 and 4 mu m. The study confirmed the applicability of the IOM and Button samplers. The new foam product followed the respirable criteria well. However, the foam sampler was unstable for measuring inhalable dust, probably due to its moisture absorption. In addition, high dust loads should be avoided with the foam sampler due to increase in filtering efficiency. The concentrations of inhalable dust measured with the Button sampler, the Grimm monitor, and the impactor sampler were usually close to those measured with the reference sampler. On the other hand, impactor sampling yielded higher respirable dust concentrations than the reference method in the field, which may have been caused by particle bounce; high dust loads should be avoided while using the impactor. The results also showed that the Grimm monitor enables real-time dust concentration determinations that are accurate enough for routine monitoring of occupational exposure and for testing efficiency of control measures in workplaces. 相似文献
2.
Eun Gyung Lee Peter J. Grimson William P. Chisholm Michael L. Kashon Xinjian He Christian L’Orange 《Journal of occupational and environmental hygiene》2019,16(3):250-257
This study evaluates the performance of the disposable inhalable aerosol sampler (DIAS), a new sampler developed to be more cost-effective than the traditional inhalable particle samplers and comparable to the inhalable particle sampling convention. Forty-eight pairs of the DIAS prototype and the IOM sampler were utilized to collect copper exposure measurements (23 personal and 25 area) at an electrorefinery facility. The geometric mean (GM) value of ratios of exposure data (DIAS/IOM) was 1.1, while the GM of ratios (DIAS/IOM) was 1.6 for the area exposure data, revealing 84% of the ratios were greater than one. For both personal and area exposure data, the concordance correlation coefficient tests revealed significant disagreements between the two types of samplers and suggested precision as the source of the disagreement. The estimated mean concentration was higher for the DIAS compared that for the IOM for the area exposure data (p < 0.05), while the results were comparable for the personal exposure data (p = 0.49). Overall, the DIAS generated higher exposure results compared to the IOM sampler for the area exposures. For the personal exposures, the findings were inconclusive due to inconsistent results of factors aforementioned. This study is limited to one metal component (copper) of the dust at a worksite. To date, this is the first field evaluation using personal exposure data to test the performance of the DIAS and the second evaluation using area exposure data. Thus, it will be necessary to conduct additional field evaluations with various elements to further evaluate the performance of the DIAS. In addition, particle migration to the internal walls of the cap was observed during the transportation of collected samples to a laboratory for both sampler types (6.4% for the DIAS and 7.4% for the IOM). Occupational health and safety professionals should be aware of potential errors caused from transferring samples from a field to a laboratory and should be careful not to exclude particles collected on the caps. 相似文献
3.
Kenny L Chung K Dilworth M Hammond C Wynn Jones J Shreeve Z Winton J 《The Annals of occupational hygiene》2001,45(1):35-42
Porous polyurethane foams provide a low-cost method for separating dust into health-related fractions in accordance with recognized sampling conventions. A number of dust sampling instruments that make use of foam selectors have been described in recent literature, but practical experiences of using these instruments in real workplaces have not been widely reported. An IOM inhalable dust sampler incorporating a respirable-fraction selector foam was evaluated in a range of industries, for general occupational dust monitoring. The key issues addressed were those that determine the practicability of the instrument, such as limitations on particulate loading, losses or movements of particles during transportation of samples, and equivalence with conventional respirable dust sampling methods. The new sampler was found to be satisfactory in all these respects. The minor problems experienced have been addressed during the design of the production version of the foam cassette, which is available as an accessory for the existing IOM inhalable dust sampler. The key advantage of the new dust sampler is that it measures both inhalable and respirable dust concentrations in a single sample (hence the name: dual-fraction dust sampler). Therefore, it saves both time and money in industries where both inhalable and respirable dust are routinely monitored. 相似文献
4.
The performance of three, portable, real-time dust monitors was investigated inside a calm air dust chamber for a range of industrial dusts and two sizes of aluminium oxide dust. The instruments tested were the Split 2 (SKC Ltd), Microdust Pro (Casella Ltd) and DataRam (Thermo Electron Ltd), which sampled either passively or actively by connecting a manufacturer-supplied, size-selective adaptor and an air sampling pump to the inlet of the monitor. Two size-selective adaptors were tested with the Split 2: the GS-3 cyclone adaptor and the Institute of Occupational Medicine (IOM) inlet with porous foam inserts. Similarly, two size-selective adaptors were tested with the Microdust Pro: the Higgins-Dewell cyclone adaptor and the conical inhalable sampler (CIS) adaptor with porous foam inserts. The DataRam was tested with a GK 2.05 cyclone adaptor since there was no porous foam adaptor available. The instruments' responses were compared with the reference dust samplers: Casella Higgins-Dewell cyclone for the respirable fraction and IOM sampler for the inhalable fraction. The response of the dust monitors was found to be linear with respirable dust concentration when operated either passively or actively using the cyclone size-selective inlets. Their responses were, however, lower when operated actively with the cyclone adaptors compared to the passive operation and lower still when used with the porous foam inserts. There was also often more scatter in the porous foam measurements, attributable to variable clogging of the foams caused by inconsistent loading with dust. The dust monitor responses were sensitive to changes in particle size when operated passively but much less so in active mode with the cyclone adaptors. The Microdust Higgins-Dewell cyclone adaptor measurements agreed closely with the reference respirable concentration for all dusts, whereas those for the DataRam GK 2.05 and Split 2 GS-3 cyclone adaptors were different to the reference. Concentrations measured with the foam adaptors were considerably lower than both the reference cyclone samplers and the dust monitor cyclone adaptors and increasingly undersampled as they became loaded with dust. Inhalable dust measured with the Split 2 IOM adaptor agreed closely with the reference IOM inhalable samplers, whereas the Microdust CIS adaptor underestimated the inhalable concentration compared to the reference. 相似文献
5.
Rando R Poovey H Mokadam D Brisolara J Glindmeyer H 《Journal of occupational and environmental hygiene》2005,2(4):219-226
The RespiCon sampler is a multistage virtual impactor that simultaneously collects the ISO/CEN/ACGIH size fractions of inhalable, thoracic, and respirable particulate matter. The field performance of the device for measurement of industrial wood processing dust was evaluated against reference size-selective samplers: the IOM sampler (inhalable dust), the GK 2.69 cyclone (thoracic dust), and the SKC aluminum cyclone (respirable dust). Seventy-one sets of area samples were collected from 10 wood processing plants, with the samplers mounted either in the free-field or on a two-dimensional bluff body. The geometric mean (range) dust levels across all plants measured by the reference samplers were: inhalable, 1.35 mg/ m3 (0.11-11.06); thoracic, 0.31 mg/m3 (0.05-1.38); and respirable, 0.10 mg/m3 (0.02-0.54). In comparing the RespiCon with the reference samplers, there was no significant difference between sampling in the free-field versus bluff-body modes. For inhalable dust, there was no significant difference between the RespiCon and the IOM sampler after applying a correction factor of 1.5 to the extrathoracic data obtained from the RespiCon. Without the correction factor, the RespiCon undersample inhalable dust by an average of 23%. For thoracic dust, the RespiCon was shown to oversample the extrathoracic dust fraction resulting in an overall error of 48%. A simple correction based on the inhalable and thoracic dust levels reported by the RespiCon is proposed. For respirable dust, there was a significant difference between the RespiCon and the SKC cyclone, but the data were equivocal due to imprecision in measurement of the low respirable dust concentrations encountered and the likelihood of bias in the reference sampler. Overall, the RespiCon sampler appears to be a suitable size-selective sampling device for industrial wood processing dust, although adjustments should be made to the inhalable and thoracic dust results. 相似文献
6.
Field comparison of inhalable aerosol samplers applied in the european rubber manufacturing industry
de Vocht F Huizer D Prause M Jakobsson K Peplonska B Straif K Kromhout H 《International archives of occupational and environmental health》2006,79(8):621-629
Several studies have been done in Europe to evaluate exposure to dust and fumes in the rubber industry. However, different aerosol sampling devices have been used which perform differently depending on the environmental conditions and particle size distribution. To compare measurements of rubber dust and fumes among countries and surveys we initiated a field comparison of personal inhalable samplers using a novel reference inhalable aerosol sampler (CALTOOL). Measurements were done in four factories in the Netherlands, Sweden, Poland and Germany in the mixing and milling and curing department. The Seven-hole sampler, PAS-6 sampler, Millipore (25 and 37 mm) cassette, IOM sampler and a Polish sampler were mounted on the reference CALTOOL device and used simultaneously. All samplers except the IOM sampler under-sampled inhalable dust. To compare measurements from different studies and countries, correction factors should be applied to all but the IOM sampler, which was the only sampler that performed similar to the CALTOOL sampler. 相似文献
7.
Inhalable and total dust sampling devices were compared for evaluating airborne dust in swine confinement buildings. Measurements from three swine facilities (n = 77 paired means) were obtained by area sampling using the IOM (Institute of Occupational Medicine, Edinburgh, U.K.) inhalable dust sampler and a 37-mm closed-face total (TCF) dust sampler. The overall geometric mean IOM concentration (1.18 mg/m(3), geometric standard deviation [GSD] = 2.00) was significantly greater (P < 0.05) than the overall geometric mean TCF concentration (1.08 mg/m(3), GSD = 1.98). Regression analysis with IOM and TCF values as independent and dependent variables, respectively, yielded a factor of 0.86 (+/-0.04 95% confidence interval), which can be used to estimate TCF values from the IOM measurements. Additional paired sampling data were obtained to compare the following pairs of dust samplers: (1) IOM sampler and conical inhalable sampler (CIS) (n = 20 paired means), (2) IOM and open-face total (TOF) dust samplers (n = 14), (3) CIS and TCF samplers (n = 19), and (4) TCF and TOF samplers (n = 8). Paired t-tests showed significantly (P < 0.05) higher IOM concentrations than the CIS sampler; no significant difference (P > 0.05) was found for the other three pairs compared. It may be necessary to establish work-specific conversion coefficients to obtain a reasonable estimate of worker exposure to total dust from measurements using other types of dust sampling devices. 相似文献
8.
Thorpe A 《The Annals of occupational hygiene》2007,51(1):97-112
The performances of five portable direct-reading dust monitors were investigated in a wind tunnel for a range of industrial dusts and three sizes of aluminium oxide test dust to mainly determine their suitability for measuring the inhalable fraction of airborne dust in workplaces. The instruments tested were Split 2 (SKC Ltd), Sidepak (TSI Inc.), Dataram (Thermo Electron Ltd), PDS-2 (Sibata Scientific Technology Ltd) and the Respicon TM (Hund Ltd). The instruments' responses were compared with reference dust samplers. These were the IOM sampler for the inhalable fraction and the Casella cyclone sampler for the respirable fraction. All instruments are predominantly responsive to and are designed to measure particles in the respirable size range, although two of the instruments, the Split 2 and Respicon TM, are claimed to be capable of measuring inhalable-sized particles. For the purpose of the tests, major modifications to an existing wind tunnel dust injection system were made to facilitate the generation of uniform concentrations of large inhalable-sized dust particles at low air velocities. Each monitor greatly underestimated the measurement of inhalable concentration for all the dusts tested, although the linearity was good over a wide range of concentrations for any particular size distribution of dust. However, their calibration factors, defined as the ratio of reference inhalable concentration to monitor concentration, were especially sensitive to changes in particle size as the response of the instruments decreased rapidly with increasing particle size. The monitors generally overestimated the measurement of respirable dust concentration by up to a factor of about 2, apart from the PDS-2, which underestimated it by a factor of up to 3. There was, however, a great deal more scatter in the reference respirable concentration measurements owing to the collection of small dust samples. Therefore, monitor linearity and effects of monitor response to changes in particle size could not be accurately investigated for the respirable fraction. The sampling head of the Split 2 monitor incorporates an IOM inlet and filter to gravimetrically collect the inhalable fraction of airborne dust. This can give a concurrent reference measure of inhalable airborne dust concentration. However, poor sealing within the sampling head resulted in some of the sampled dust not reaching the backup filter. This resulted in the Split 2 underestimating the reference inhalable dust concentration, which meant that it could not be accurately used as a calibration standard. Communications with the manufacturers have since revealed that the sampling head has recently been redesigned in order to improve the seal and eliminate leakage. The Respicon sampler gravimetrically underestimated the inhalable dust concentration, and did so increasingly as the particle size increased. 相似文献
9.
Teikari M Linnainmaa M Laitinen J Kalliokoski P Vincent J Tiitta P Raunemaa T 《AIHA journal : a journal for the science of occupational and environmental health and safety》2003,64(3):312-318
The performances of eight sampling devices were tested with mineral dusts in the laboratory and in a talc production plant. The IOM sampler was chosen as the reference method for inhalable dust, and the IOM samplers provided with the porous plastic foam media were used as the reference methods for both the thoracic and respirable aerosols. The other size-selective instruments tested included the Respicon virtual impactor, the optical GRIMM aerosol monitor, and a two-stage cascade impactor with cut points of 10 and 4 microm. The 37-mm cassettes were also included both as open- and closed-face versions. The study confirmed the usability of the IOM samplers for mineral dust, not only in its original version for the inhalable fraction but also its modified versions for the thoracic and respirable fractions. A high correlation with the two-stage impactor results is an indication of good reproducibility. The results increased the evidence that the 37-mm cassette is a poor indicator of inhalable aerosol. The concentrations obtained with both cassette methods were not only systematically too low but also showed large collection efficiency variability. Therefore, the results cannot be corrected by using correction factors. The concentrations of inhalable aerosol measured with the Respicon were generally low, but its performances for the thoracic and respirable fractions were closer to those for the reference samplers. The results also indicate that the GRIMM monitor is well-suited for such mineral dust determinations when very good accuracy is not required, but the immediate availability of the result is more important. 相似文献
10.
Robert J. Vercellino Rodney G. Handy Kyeong T. Min Scott C. Collingwood 《Journal of occupational and environmental hygiene》2018,15(7):559-567
Exposure to occupational aerosols are a known hazard in many industry sectors and can be a risk factor for several respiratory diseases. In this study, a laboratory evaluation of low-cost aerosol sensors, the Dylos DC1700 and a modified Dylos known as the Utah Modified Dylos Sensor (UMDS), was performed to assess the sensors’ efficiency in sampling respirable and inhalable dust at high concentrations, which are most common in occupational settings. Dust concentrations were measured in a low-speed wind tunnel with 3 UMDSs, collocated with an aerosol spectrometer (Grimm 1.109) and gravimetric respirable and inhalable samplers. A total of 10 tests consisting of 5 different concentrations and 2 test aerosols, Arizona road dust and aluminum oxide, were conducted. For the Arizona road dust, total particle count was strongly related between the spectrometer and the UMDS with a coefficient of determination (R2) between 0.86–0.92. Particle count concentrations measured with the UMDS were converted to mass and also were related with gravimetrically collected inhalable and respirable dust. The UMDS small bin (i.e., all particles) compared to the inhalable sampler yielded an R2 of 0.86–0.92, and the large bin subtracted from the small bin (i.e., only the smallest particles) compared to the respirable sampler yielded an R2 of 0.93–0.997. Tests with the aluminum oxide demonstrated a substantially lower relationship across all comparisons. Furthermore, assessment of intra-instrument variability was consistent for all instruments, but inter-instrument variability indicated that each instrument requires its own calibration equation to yield accurate exposure estimates. Overall, it appears that the UMDS can be used as a low-cost tool to estimate respirable and inhalable concentrations found in many workplaces. Future studies will focus on deployment of a UMDS network in an occupational setting. 相似文献
11.
Lidén G Melin B Lidblom A Lindberg K Norén JO 《Applied occupational and environmental hygiene》2000,15(3):263-276
Parallel personal sampling was carried out with the open-face filter cassette and the IOM sampler for inhalable dust for nine types of organic dust. Parallel samples numbering 749 were obtained from 152 plants. Extremely large values and outliers were disregarded, and the remaining data for each type of dust were divided into subsets according to type of product or work task, and analyzed with the aid of linear regression. The coefficient of regression for each subset ranged between 0.2 and 0.7. Hypothetical occupational exposure limits (OELs) for inhalable dust were calculated based on the linear relation obtained between the dust concentrations measured with the open-face filter cassette and the IOM sampler. The fraction of person days with time-weighted average (TWA) concentrations exceeding the calculated hypothetical OELs for inhalable dust was obtained from the distribution of measured TWA inhalable dust concentrations. Based on the results of this study and the difference in sampling efficiency for large particles between the two samplers, it was concluded that the numerical value of the OEL for inhalable dust may be set at approximately twice the numerical value of the corresponding limit value for "total dust." Additional consideration of recently discovered health effects, and technical and economical factors may result in other numerical values of future OELs for inhalable dust. 相似文献
12.
Astrakianakis G Seixas N Camp J Smith TJ Bartlett K Checkoway H 《Journal of occupational and environmental hygiene》2006,3(8):418-427
The results of a field survey at three Shanghai textile factories were used to compare the performance of the Chinese dust sampler (CDS) with the standard American sampler, vertical elutriator (VE). Side-by-side samples using a CDS and a VE were collected in seven specific manufacturing processes, with additional area and personal samples collected with a modified Institute of Occupational Medicine (IOM) personal inhalable sampler. Filters were analyzed for mass and endotoxin concentration. The geometric mean (GM) of the samples collected by the CDS was 0.79 mg/m3 (geometric standard deviation [GSD] 1.9) compared with a GM of 0.31 mg/m3 (GSD 1.7) for the VE measurements. The correlation coefficient for the CDS and VE samples was 0.35. The CDS, a high-volume total dust area sampler, collects 2 to 10 times more dust than the VE, a size-selective method, depending on the manufacturing process. In spinning at Factory A, the VE and CDS measured concentrations of 0.15 mg/m3 and 1.62 mg/m3, respectively. Cotton dust concentration measurements collected by the IOM sampler demonstrated that personal exposure concentrations were significantly higher (GM 1.84 mg/m3, GSD 1.6) than fixed-position area samples (GM 0.68 mg/m3, GSD 1.9). The endotoxin concentration based on the VE samples was 366 EU/m3, with the highest levels found in the specific manufacturing process drawing (1871 EU/m3) and the lowest in spinning (43.5 EU/m3). The results of the field comparison were used to convert historic CDS data into comparable exposures and to assign retrospective exposures to subjects included in a case-cohort study of lung cancer among female textile workers in Shanghai. 相似文献
13.
Bogdanovic J de Pater AJ Doekes G Wouters IM Heederik DJ 《The Annals of occupational hygiene》2006,50(2):131-136
BACKGROUND: Exposure to airborne wheat allergen is a well-known cause of bakers' allergy and asthma. Airborne wheat allergen can be measured by enzyme immunoassays (EIAs) in extracts of inhalable dust samples, but only limited knowledge is available on the size distribution of wheat allergen-carrying particles. Recently, a new sampling medium, porous polyurethane foam, has been introduced for the size-selective sampling of airborne dust in various occupational settings. We investigated the applicability of these foams for size-selective wheat allergen measurements. METHODS: Personal and stationary measurements were performed in a flour mill, using respirable and thoracic foams inserted into the conventional IOM inhalable sampler, together with PTFE (Teflon) filters. Foams and filters were eluted and wheat allergen levels determined by human IgG4 inhibition EIA. RESULTS: Wheat allergen levels could be determined in both filter and foam eluates. Inhalable dust levels from filters and foams ranged from 1.4 to 53 mg m(-3), and wheat allergen levels from 15 to 580 microg m(-3). The allergen was mainly borne on particles with D(ae) (particle aerodynamic diameter) > 10 microm and particles with 4 microm < D(ae) < or = 10 microm, accounting for 54.5-77.5% and 18.9-43.2% of the total allergen yield, respectively. Less than 4% of airborne wheat allergen was carried by particles smaller than 4 mum (respirable fraction). CONCLUSIONS: Measurement of wheat allergen in dust fractions trapped in respirable and thoracic foams is technically feasible. Both wheat flour dust and wheat allergen are mainly concentrated in larger particle-size fractions (extrathoracic and tracheobronchial). 相似文献
14.
Maynard AD 《The Annals of occupational hygiene》2002,46(6):511-522
It has been suggested that the non-size-selective sampling methods currently used for fibrous aerosols potentially lead to the presence of large compact particles, agglomerates and fibre clumps in samples, which in turn reduce the accuracy and precision of the manual fibre counting techniques employed to analyse samples. The use of thoracic size-selective samplers has been proposed as an alternative, leading to the prevention of large particles reaching the collection substrate while at the same time bringing fibre sampling into line with general occupational aerosol sampling methodologies. Thoracic samplers should give good agreement with current sampling methods under ideal conditions based on aerodynamic fibre properties. However, the effect of fibre length on sampling efficiency is not known. The sampling efficiency of five thoracic samplers was therefore measured as a function of fibre length for respirable fibres between 10 and 60 microm long. These included the commercially available GK2.69 cyclone and the CATHIA sampler, the IOM thoracic sampler, a modified version of the SIMPEDS cyclone and a modified version of the IOM inhalable sampler. Length-monodisperse fibres were generated using a dielectrophoretic fibre classifier and sampler penetration was measured as a function of fibre length. No length-dependent sampling effects were observed for the CATHIA, GK2.69, modified SIMPEDS and modified IOM inhalable samplers for fibres <60 microm. Data for the IOM thoracic sampler showed a significant trend of reducing sampling efficiency for fibres >30 microm. Overall, the laboratory results indicated that the five sampler types are likely to perform as well as or better than the currently used 25 mm cowled sampler in the field. 相似文献
15.
Brouwer DH Links IH De Vreede SA Christopher Y 《The Annals of occupational hygiene》2006,50(5):445-452
A simulated workplace study was conducted to investigate the relation between inhalation exposure and dustiness determined with a rotating drum dustiness tester. Three powders were used in the study, i.e. magnesium stearate, representing a very dusty powder, and aluminium oxide and calcium carbonate, representing low and very low dusty powders, respectively. Two scenarios of handling small volume of powders were included; sweeping/cleaning and scooping/weighing/adding. Size-selective dust exposure was assessed using MultiDust (dual-fraction) IOM and RespiCon sampling heads. For the present operation scenarios, dustiness showed itself to be the major determinant of exposure and explained approximately 70% of the exposure variances. The ratios of respirable and inhalable fractions as determined by dustiness tests were comparable with the ratios observed for exposure. The results emphasize the relevance of dustiness as a parameter to characterize substances according to potential for exposure. 相似文献
16.
Mark J. Nieuwenhuijsen Kyle S. Noderer Marc B. Schenker 《American journal of industrial medicine》1997,32(4):355-363
Measuring exposure levels for epidemiologic research is time consuming and expensive and therefore subjective exposure estimates are sometimes used instead. In this study we related the subjective dust exposure estimates of workers in California agriculture to personal dust exposure measurements. One hundred and twenty-four observations were available for comparison of subjective dust estimates and inhalable dust measurements and 129 observations for comparison of subjective dust estimates and respirable dust measurements. Individual subjective dust estimates showed weak to moderate correlations with measured dust concentrations for both the inhalable (Rs = 0.67) and respirable dust fraction (Rs = 0.36). The within-worker reliability coefficients were low (0.2 and 0.1, respectively). Grouped subjective dust estimates performed better and showed a consistent increase with average measured dust levels, in particular for the inhalable dust fraction (R2 = 0.81). Age, the number of years working in agriculture, education level, the presence of any respiratory symptoms, and the language of the questionnaire did not have a significant independent effect on the relationship between measured dust levels and subjective dust estimates. California agricultural workers appear to be reasonably good at estimating inhalable dust levels, in particular if an average of many different workers is taken, but they are unable to provide good estimates of respirable dust levels. Measuring dust levels remains the preferred option. Am. J. Ind. Med. 32:355–363, 1997. © 1997 Wiley-Liss, Inc. 相似文献
17.
Mehta AJ Wang XR Eisen EA Dai HL Astrakianakis G Seixas N Camp J Checkoway H Christiani DC 《The Annals of occupational hygiene》2008,52(1):45-54
OBJECTIVES: To determine if work area measurements of endotoxin and/or cotton dust obtained from the vertical elutriator (VE) can be used to predict levels of personal endotoxin exposure as measured by the Institute of Occupational Medicine (IOM) inhalable dust sampler in the cotton textile industry. METHODS: Fifty-six work area cotton dust samples were collected from 14 areas and 82 personal cotton dust samples were collected from 41 workers in three textile mills (Mills A, B and C) in Shanghai, China. Cotton dust concentrations were determined gravimetrically from sample filters, of which endotoxin concentrations were determined using a kinetic chromogenic modification of the limulus amoebocyte lysate assay. Linear regression models were used to determine the association between log IOM personal endotoxin concentration and log VE area endotoxin concentration. RESULTS: Median cotton dust and endotoxin concentrations measured from VE area samples in the three mills were 0.36 mg m(-3) and 1280.76 endotoxin units per cubic meter (EU m(-3)), respectively, compared to 1.74 mg m(-3) and 2226.83 EU m(-3) from IOM personal samples. Excluding samples from weaving processes, we observed linear associations between VE area measures of endotoxin and IOM personal endotoxin concentrations; VE area concentration of endotoxin explained 83 and 89% of the total variation in IOM personal endotoxin concentration for Mills A and B, respectively (Mill A: R2 = 0.83, P < 0.0001; Mill B: R2 = 0.89, P < 0.0001). Although area measures of cotton dust was also a significant predictor of person endotoxin, the model explained less of the variance in personal endotoxin measurements. CONCLUSIONS: Specific to the conditions of the textile mills investigated in this study, work area measurements of endotoxin, but not cotton dust, may be reasonable proxies for personal levels, at least for rank-ordering exposures. 相似文献
18.
The study was concerned with the measurement of inhalable aerosol exposures in the carbon black production industry. The primary goal of the study was to determine the extent to which inhalable aerosol exposure, as measured by the Institute of Occupational Medicine (IOM) personal inhalable sampling head, compared to "total" aerosol exposure, as measured by traditional methodology. A secondary objective was the evaluation of another inhalable aerosol sampler for carbon black aerosol measurement. In addition, an exploratory evaluation of the applicability of the National Institute for Occupational Safety and Health (NIOSH) analytical method (Method 5040) for the determination of carbon black, measured as elemental carbon, was conducted. A field study was carried out in a number of North American carbon black production plants using three samplers: the 2 Lpm IOM sampler as a reference sampler for the inhalable fraction, the 2 Lpm closed-face 37-mm plastic cassette that has been used for many years for total aerosol, and the 3.5 Lpm GSP sampler that has recently been identified by some as a possible candidate for inhalable aerosol. No such studies have previously been reported for the carbon black industry. Further, there have been no reports of the GSP performance in direct comparison to a reference instrument like the IOM sampler. The results showed that inhalable aerosol exposures for workers in carbon black production and packing areas were higher than the corresponding total aerosol exposures by a factor of nearly three, implying the presence of significantly coarser aerosol than previously thought based simply on knowledge of the carbon black production process. The fact that the aerosols collected in portions of the process comprised high proportions of non-elemental carbon particulate was thought likely to be responsible, underlining the need to consider whether gravimetric assessment for such exposure is the most appropriate metric. In addition, and somewhat surprisingly, the GSP sampler emerged clearly as a good alternative to the IOM sampler for collecting inhalable aerosol in carbon black industry workplaces like those studied (although this conclusion cannot yet be extended to other workplaces). 相似文献
19.
Personal exposure to dust, endotoxin and crystalline silica in California agriculture 总被引:1,自引:0,他引:1
Nieuwenhuijsen MJ Noderer KS Schenker MB Vallyathan V Olenchock S 《The Annals of occupational hygiene》1999,43(1):35-42
AIMS: The aim of this study was to measure personal exposure to dust, endotoxin and crystalline silica during various agricultural operations in California over a period of one year. METHODS: Ten farms were randomly selected in Yolo and Solano counties and workers were invited to wear personal sampling equipment to measure inhalable and respirable dust levels during various operations. The samples were analysed for endotoxin using the Limulus Amebocyte Lysate assay and crystalline silica content using X-ray diffraction. In total 142 inhalable samples and 144 respirable samples were collected. RESULTS: The measurements showed considerable difference in exposure levels between various operations, in particular for the inhalable fraction of the dust and the endotoxin. Machine harvesting of tree crops (Geometric mean (GM) = 45.1 mg/m3) and vegetables (GM = 7.9 mg/m3), and cleaning of poultry houses (GM = 6.7 mg/m3) showed the highest inhalable dust levels. Cleaning of poultry houses also showed the highest inhalable endotoxin levels (GM = 1861 EU/m3). Respirable dust levels were generally low, except for machine harvesting of tree crops (GM = 2.8 mg/m3) and vegetables (GM = 0.9 mg/m3). Respirable endotoxin levels were also low. For the inhalable dust fraction, levels were reduced considerably when an enclosed cabin was present. The percentage of crystalline silica was overall higher in the respirable dust samples than the inhalable dust samples. CONCLUSIONS: Considerable differences exist in personal exposure levels to dust, endotoxin and crystalline silica during various agricultural operations in California agriculture with some operations showing very high levels. 相似文献
20.
In 2000, the American Conference of Governmental Industrial Hygienists (ACGIH(R)) changed its 1971 threshold limit value (TLV) for 8-hour time-weighted average (TWA) exposure to asphalt from 5 mg/m(3) total particulate (generally < or =40 micrometer [microm] diameter) to 0.5 mg/m(3) inhalable particulate (< or =100 microm aerodynamic diameter) as benzene-soluble aerosol. To date, no inhalable particulate sampling method has been standardized and validated for asphalt fume. Furthermore, much of the historical data were collected using total particulate samplers, and the comparability of total versus inhalable size fractions of asphalt fume is not known. Therefore, the present study compared results from two types of asphalt fume samplers: 1) a traditional total particulate sampler with a 37-mm filter in a closed-face cassette with a 4-mm orifice (NIOSH 5042) versus (2) an inhalable particulate sampler designed by the IOM with a 15-mm orifice. A total of 75 simultaneous pairs of samples were collected, including personal and area samples from 19 roofing and asphalt production facilities operated by 7 different manufacturers. Each sample was analyzed for total mass collected and for benzene-soluble mass. Data from the two sampling methods (total versus inhalable) were comparable for asphalt fumes up to an aerosol concentration of 10 mg/m(3). However, we conclude that the traditional total particulate method is preferable, for this reason: The vast majority of asphalt fume particles are <12.5 microm in diameter. The traditional sampler is designed to collect primarily particles < or =40 microm, while the IOM sampler is optimized for collecting particles < or =100 microm. Thus, the traditional sampler is less likely than the IOM sampler to collect the larger-size fraction of airborne particles, most of which are non-asphalt dust. 相似文献