首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到19条相似文献,搜索用时 93 毫秒
1.
目的 总结Stanford A型主动脉夹层的治疗经验,评价其外科手术疗效。 方法 回顾性分析2006年10月至2013年3月兰州军区兰州总医院48例Stanford A型主动脉夹层行外科手术治疗的临床资料,其中男41例,女7例;年龄26~72 (47.6±9.2) 岁。急性Stanford A型主动脉夹层(发病至确诊<14 d) 43例,慢性5例。主动脉瓣中重度关闭不全19例+主动脉瓣良好、但合并马方综合征6例,行Bentall+全弓置换+支架象鼻术;累及主动脉根部、但瓣膜功能良好的8例行改良David+全弓置换+支架象鼻术;累及升主动脉10例行升主动脉+全弓置换+支架象鼻术;累及部分主动脉弓5例行升主动脉+次全弓置换术。出院后于术后3、6、12个月随访,以后每年随访1次。随访内容包括:患者的生存情况、血压控制情况、有无疼痛复发、运动、活动情况和复查主动脉计算机断层扫描成像(computerized tomography arteriography,CTA)。 结果 全组体外循环时间121~500 (191.4±50.6) min,主动脉阻断时间58~212 (112.3±31.7) min;停循环+选择性脑灌注时间26~56 (34.8±8.7) min;术后呼吸机辅助时间32~250 (76.2±35.6) h;住ICU时间3~20 (7.1±3.4) d。术后24 h胸腔引流量680~1 600 (1 092.5±236.3) ml。围术期死亡7例,病死率14.5%,其中死于多器官功能衰竭2例、低心排血量综合征2例、肾功能衰竭1例、迟发性难治性出血1例、昏迷1例。围术期发生其它并发症20例,经治疗均痊愈或好转出院。随访38例,随访率92.7%(38/41),随访时间3~48 (13.0±8.9) 个月;失访3例。随访期间36例存活,无与主动脉夹层相关的死亡,因其它慢性疾病死亡2例。无因主动脉夹层继续形成、假腔扩张行二次手术患者,术后6个月CTA检查未见吻合口渗漏及人工血管扭曲或血流不畅。 结论 根据主动脉夹层破口的位置、升主动脉直径及夹层累及范围等,选择合适的手术方式、手术时机及脏器保护策略是提高Stanford A型主动脉夹层治疗效果的关键。应用腋、股动脉联合灌注及提高术中最低温度等策略治疗Stanford A型主动脉夹层可获得良好的效果。  相似文献   

2.
全主动脉弓置换加支架象鼻手术治疗A型主动脉夹层   总被引:7,自引:1,他引:7  
目的介绍全主动脉弓置换加支架象鼻手术治疗A型主动脉夹层的方法,总结其治疗经验。方法2007年1月至2008年11月,采用四分支人工血管行全主动脉弓置换加覆膜支架象鼻手术治疗A型主动脉夹层10例,其中急性夹层8例,慢性2例。10例均在深低温停循环及选择性脑灌注下完成手术,对5例合并主动脉瓣中至重度关闭不全的患者同期行Bentall手术,余5例行升主动脉置换术。结果1例于术后26d因多器官功能衰竭死亡;余9例均顺利康复出院,无严重神经系统并发症。术后随访2~25个月,均生存,心功能Ⅰ~Ⅱ级。结论采用四分支人工血管行全主动脉弓置换加覆膜支架象鼻手术是治疗A型夹层的有效手术方式,手术操作技术和脑保护措施是决定手术效果的关键。  相似文献   

3.
2004年1月至2005年5月,我们对12例DeBakey Ⅰ型主动脉夹层动脉瘤病人应用全主动脉弓置换加支架象鼻技术行主动脉弓全弓置换,现报道如下.  相似文献   

4.
目的总结应用三分支全主动脉弓覆膜支架治疗老年Stanford A型主动脉夹层的临床经验。方法河南省胸科医院心血管外科2008年12月至2012年12月施行三分支全主动脉弓覆膜支架植入术治疗老年Stanford A型主动脉夹层患者46例,其中男37例、女9例,年龄65~75(68.2±5.0)岁。行改良David术6例,Bentall术1例,Wheat术2例,升主动脉置换术37例。结果全组无手术死亡病例。体外循环时间135~183(131.1±10.5)min,主动脉阻断时间8l~100(61.5±1813)min,选择性脑灌注时间19~28(24.4±5.6)min。术后出现低心排血量综合征3例,急性肾功能衰竭2例,胸腔积液5例,肺部感染2例,胸骨哆开1例,经治疗均痊愈出院。全部病例随访3~12个月,未发生支架相关并发症。结论应用三分支全主动脉弓覆膜支架植入治疗StanfordA型主动脉夹层操作简单,成功率高,并发症少,尤其适合不能耐受传统手术的老年患者。  相似文献   

5.
目的 探讨主动脉弓去分支杂交手术治疗Stanford A型主动脉夹层的效果。方法 回顾性分析2018年9月至2022年3月我院收治的32例急性主动脉夹层的临床资料,其中A型主动脉夹层27例,B型夹层逆撕累及升主动脉及弓部5例。所有患者均行主动脉弓去分支杂交手术。结果 所有患者均完成去分支杂交手术,无术中更改为全弓置换手术者,无围术期死亡。其中同期行Bentall手术5例,主动脉瓣成形术6例,主动脉瓣置换8例。3例患者术后造影提示Ⅰ型内漏(9.4%),其中2例为轻度,未予进一步处理,1例为中度,予球囊扩张后内漏消失。体外循环时间为(142.6±25.7)min;主动脉阻断时间为(96.4±13.8)min;无深低温停循环时间,呼吸机使用时间为(21.7±4.8)h; ICU停留时间为(3.8±1.3)d;术后住院时间(16.8±3.7)d。1例患者因术前肾功能不全,术后早期发生急性肾功能衰竭,行床旁血滤治疗后恢复至术前水平。2例患者因术前呼吸功能不全,术后出现重度呼吸功能障碍,经积极抗感染和加强肺部护理后恢复。结论 主动脉弓去分支杂交手术是急性A型主动脉夹层的新型治疗方法,具有手术时间短...  相似文献   

6.
目的总结和评价"改良"次全弓置换加支架象鼻手术治疗Stanford A型主动脉夹层患者的临床疗效。方法 2009年12月至2011年1月,中国医科大学附属第一医院接收47例Stanford A型主动脉夹层患者行"改良"次全弓置换加支架象鼻手术,其中男35例,女12例;年龄29~86(57.9±16.0)岁。患者均依据术前主动脉计算机断层扫描动脉成像诊断分型,在深低温停循环选择性脑灌注下施行手术;近心端采用升主动脉置换术29例,Bentall手术11例,Wheat手术4例,David手术3例;同期行冠状动脉旁路移植术(CABG)5例。结果体外循环时间(136±32)min,主动脉阻断时间(97±28)min,深低温停循环选择性脑灌注时间(27±11)min。47例患者中住院期间死亡2例(4.25%,2/47),术后一过性精神障碍2例(4.25%,2/47),术后出现截瘫1例(2.12%,1/47),二次开胸止血4例。生存的45例患者均于出院前及术后6个月行主动脉3维CT血管造影(3D CTA)检查显示,降主动脉内支架血管膨胀良好,气管隆突及腹腔干平面真腔较术前明显扩大(P0.05);术后随访1~13个月,无因夹层进展需二次手术及动脉瘤破裂患者。结论 "改良"次全弓置换术加支架象鼻手术是治疗弓部三分支血管无破口的Stanford A型主动脉夹层安全、有效的方法,改良之处在于简化手术,缩短了手术时间、体外循环和深低温停循环时间,减少了手术相关并发症的发生;近期效果良好。  相似文献   

7.
急性Stanford A型主动脉夹层的外科治疗   总被引:1,自引:0,他引:1  
目的探讨急性Stanford A型主动脉夹层外科治疗经验、手术时机、方式,以提高手术效果。方法回顾性分析近8年来外科手术治疗的29例急性Stanford A型主动脉夹层患者的临床资料和随访结果。Stanford A型主动脉夹层外科手术治疗的主要原则为切除内膜撕裂、易破裂的部分主动脉,修复剥离内膜,再用人工血管移植成形或置换,再建主动脉管道,同期处理合并的心瓣膜、心肌缺血病变。结果全组急诊手术13例,亚急诊(限期)手术16例。术后早期死亡2例(6.9%),其中1例术后死于严重心律失常,1例死于多器官功能衰竭。术后二次开胸止血6例,发生肺部感染、呼吸衰竭3例,延迟苏醒4例,急性肾功能衰竭2例,上消化道出血1例,均经相应的处理治愈出院。随访24例(88.9%),随访时间23.6±10.1个月,1例行Bentall手术后16个月发生心内膜炎伴脑出血死亡,1例全弓置换 升主动脉置换术后26个月猝死,其余患者生活质量良好。结论尽早手术是降低急性Stanford A型主动脉夹层病死率的关键,根据夹层破口的位置、累及范围、主动脉瓣及根部增宽情况来选择相应的术式,以简化的手术、良好的疗效为原则。  相似文献   

8.
目的 研究改良双侧脑灌注在DeBakeyⅠ型急性主动脉夹层手术中应用的价值.方法 14例DeBakeyⅠ型急性主动脉夹层患者在深低温停循环下行手术治疗.术中采用主动脉弓腔内直视下行头臂干和左颈总动脉插管的改良双侧脑灌注技术进行脑保护.结果 全组体外循环190~325min,平均(241.78±31.74)min,心肌阻断时间71~133min,平均(104.36±17.07)min,脑灌注时间32~70min,平均(53.50±9.25)min.全组患者仅1例出现短暂性脑神经功能异常,无脑梗塞,脑出血等其他中枢神经系统损伤.结论 DeBakeyⅠ型急性主动脉夹层手术中,采用经主动脉弓腔内直视下行头臂干和左颈总动脉插管的改良双侧脑灌注技术进行脑保护,其方法 简便、安全、有效.  相似文献   

9.
孙氏手术治疗急性Stanford A型主动脉夹层   总被引:1,自引:0,他引:1  
目的 总结急性Stanford A型主动脉夹层采用孙氏手术(主动脉弓部替换加支架象鼻手术)的临床经验与随访结果.方法 2004年8月至2012年3月,73例急性A型夹层患者施行了孙氏手术,其中男60例、女13例,平均年龄49.6(26 ~79)岁.手术均采用深低温停循环、低流量选择性脑灌注技术.单纯行升主动脉替换加孙氏手术30例;主动脉根部替换(Bentall术)加孙氏手术10例,主动脉瓣及升主动脉替换加孙氏手术12例,主动脉瓣成形加孙氏手术21例(同时行主动脉窦重建16例),同期行冠状动脉旁路移植术( CABG)9例,术后通过CTA评价胸腹主动脉塑形及假腔愈合情况.结果 体外循环平均(248.1±69.8)min,选择性脑灌注(38.2±10.5)min.手术死亡5例(6.85%,5/73例).术后60例随访2个月~7.6年,术后3个月CTA复查显示,91.7%的患者主动脉夹层的假腔在膈肌水平形成血栓,患者术后1、5和7年的生存率分别是97%、87%和81%.结论 孙氏手术治疗急性A型主动脉夹层安全有效且远期效果令人满意.  相似文献   

10.
对8例Stanford A型主动脉夹层累及主动脉弓部的患者采取主动脉弓替换加支架“象鼻”术治疗,术前注意心理疏导,控制血压和疼痛;术后加强血流动力学、肾功能和体温监测,严密观察引流量,预防感染,加强脑部并发症的观察。结果8例均痊愈出院。提示充足的术前准备和术后细致周到的护理是亍术获得满意效果的重要保证。  相似文献   

11.
We describe a case of type B aortic dissection with large ascending aortic aneurysm occurring 12.8 years after aortic root replacement (Cabrol procedure) in a non-Marfan patient with cystic medial necrosis of the aorta. We have successfully performed an extended total aortic arch replacement using a four-branched graft through the “L-indsion” approach (a combination of a left anterior thoracotomy and upper half median sternotomy). Of note, a histological specimen from the aneurysmal ascending aortic wall revealed “healed aortic dissection” with fibrous tissue replacing the media and intima in addition to multiple foci of cystic medial necrosis.  相似文献   

12.
A 61-year-old man complained of chest pain and developed congestive heart failure due to massive acute aortic regurgitation. Computed tomographic scan demonstrated Stanford type A aortic dissection from the aortic root to common iliac arteries. David’s aortic valve sparing operation and total aortic arch replacement were applied to the patient, because the aortic dissection was extended into two aortic commissures and all arch vessels, though the tear was present at the proximal ascending aorta. The surgery was well tolerated without any significant complication.  相似文献   

13.
(Received for publication on July 8, 1996; accepted on Mar. 4, 1997)  相似文献   

14.
The successful implementation of a reoperative Bentall procedure with concomitant total aortic arch replacement after ascending aortic replacement for acute aortic dissection is infrequently reported. We performed a modified Bentall procedure with total replacement of the aortic arch in a patient suffering from worsening aortic regurgitation (AR) and residual dissection. Our strategy involved the button method for coronary reconstruction, selective cerebral perfusion, the use of a composite graft with four branches for aortic arch replacement, and the administration of high-dose aprotinin to decrease bleeding.  相似文献   

15.

Objective

To compare perioperative and long-term outcomes in patients undergoing hemiarch and aggressive arch replacement for acute type A aortic dissection (ATAAD).

Methods

From 1996 to 2017, we compared outcomes of hemiarch (n = 322) versus aggressive arch replacements (zones 2 and 3 arch replacement with implantation of 2-4 arch branches, n = 150) in ATAAD. Indications for aggressive arch were arch aneurysm >4 cm or intimal tear in the aortic arch that was not resectable by hemiarch replacement, or dissection of arch branches with malperfusion.

Results

Patients in the aggressive arch group were significantly younger (mean age: 57 vs 61 years old) and had significantly longer hypothermic circulatory arrest, cardiopulmonary bypass, and aortic crossclamp times. There were no significant differences in perioperative outcomes between hemiarch and aggressive arch groups, including 30-day mortality (5.3% vs 7.3%, P = .38) and postoperative stroke rate (7% vs 7%, P = .96). Over 15 years, Kaplan–Meier survival was similar between hemiarch and aggressive arch groups (log-rank P = .55, 10-year survival 70% vs 72%). Given death as a competing factor, incidence rates of reoperation over 15 years (2.1% vs 2.0% per year, P = 1) and 10-year cumulative incidence of reoperation (14% vs 12%, P = .89) for arch and distal aorta pathology were similar between the 2 groups.

Conclusions

Both hemiarch and aggressive arch replacement are appropriate approaches for select patients with ATAAD. Aggressive arch replacement should be considered for an arch aneurysm >4 cm or an intimal tear at the arch unable to be resected by hemiarch replacement, or dissection of the arch branches with malperfusion.  相似文献   

16.
17.
18.
19.

Objective

Our study evaluated the long-term outcomes of total arch replacement using a 4-branched graft.

Methods

From October 1999 to December 2016, 655 patients underwent total arch replacement using a 4-branched graft (pathology in the 655 patients was distributed as 399 no dissection, 149 acute dissection, and 107 chronic dissection). Two hundred nine patients (31.9%) underwent nonelective surgery. Mean follow-up term was 5.0 ± 4.1 years and follow-up rate was 97.1%.

Results

Of 655 patients who underwent total arch replacement using a 4-branched graft, operative mortality occurred in 34 patients (5.2%) and permanent neurologic deficit occurred in 24 patients (3.7%). One hundred ninety late deaths occurred, with 20 aortic event-related deaths. Overall survival was 73.1% ± 1.9% at 5 years and 54.8% ± 2.7% at 10 years. Multivariate Cox-hazard regression analysis demonstrated that older age, lower estimated glomerular filtration rate, concurrent procedures, permanent neurologic deficit, tracheostomy, and renal failure were significant risk factors for late death. Freedom from repeat operation on the aorta was 98.0% ± 0.7% at 5 years and 93.9% ± 1.8% at 10 years and freedom from additional aortic operation was 87.2% ± 1.5% at 5 years and 77.3% ± 2.7% at 10 years. The incidence of pseudoaneursym was 2.2%.

Conclusions

The long-term outcomes for patients undergoing total arch replacement using 4-branched graft are favorable. However, even in the late phase, periodic follow-up is necessary to address subsequent aorta-related events.  相似文献   

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号