干扰素氧驱动雾化吸入治疗毛细支气管炎疗效观察

目的 观察干扰素氧驱动雾化吸入辅助治疗毛细支气管炎的临床效果. 方法选择毛细支气管炎59例,随机分为治疗组32例与对照组27例,两组病人均采用规范综合治疗,在此基础上治疗组采用干扰素1ug/kg·次(最大量用至10ug)加生理盐水2～3mL氧驱动雾化吸入,每天2次.对照组采用利巴韦林10mg/kg·次(最大量用至100mg)加生理盐水2～3mL氧驱动雾化吸入,每天2次,疗程均为5d.结果 治疗组与对照组比较,在喘憋缓解、咳嗽缓解、肺部啰音消失及退热时间等方面,治疗组均优于对照组(P＜0.01),未见不良反应发生.结论 干扰素氧驱动雾化吸入治疗毛细支气管炎疗效满意.     

γ-干扰素雾化吸入治疗毛细支气管炎疗效观察

目的：探讨γ-干扰素雾化吸入治疗毛细支气管炎的疗效。方法：对132例毛细支气管炎的患儿按照治疗方法不同分为γ-干扰素治疗组67例，对照组65例，两组在使用抗生素、吸氧、吸痰、抗病毒、纠正酸中毒、镇静，合并心衰者予利尿、强心、扩管等综合治疗上相同。治疗组在综合治疗上使用γ-干扰素雾化吸入治疗。结果：γ-干扰素雾化吸入治疗组患儿咳嗽、气促、吼喘、呼吸困难和肺部哮呜音消失时间均较对照组明显缩短。（P均〈0．01）。结论：γ-干扰素雾化吸入治疗呼吸道合胞病毒（RSV）感染所致毛细支气管炎能迅速改善临床症状，缩短病程。     

干扰素肌注并雾化吸入治疗毛细支气管炎疗效观察

目的：探讨干扰素对毛细支气管炎疗效的影响。研究方法：毛细支气管炎100例随机分为治疗组60例，对照组40例，两组基础治疗相同，治疗组加用α-干扰素5×10^4 IU／（kg·日）肌注，γ-干扰素3×10^3 IU／次，雾化吸入。结果：治疗组退热时间，其他症状（如咳嗽、呼吸困难、喘鸣、干湿哆音等）消失时间与对照组比较差异有显著性，P〈0．01。结论：α-干扰素肌注配合小剂量γ-干扰素雾化吸入治疗毛细支气管炎效果较好。     

γ-干扰素合沐舒坦雾化吸入治疗小儿毛细支气管炎的疗效探讨

目的探讨γ-干扰素合沐舒坦雾化吸入治疗小儿毛细支气管炎的疗效.方法对确诊的60例毛细支气管炎患儿随机分为治疗组及对照组,每组30例.治疗组应用γ-干扰素0.5×105IU/次合α-细辛脑4mg/次加入生理盐水10ml中雾化吸入;对照组仅雾化吸入生理盐水10ml,以上治疗均每日二次.结果与对照组相比,治疗组患儿喘憋缓解时间、肺哮鸣音消失时间以及平均住院时间均缩短,治疗24小时后的血气分析恢复率高.结论γ-干扰素合沐舒坦雾化吸入治疗小儿毛细支气管炎效果好.     

γ-干扰素联用α-细辛脑雾化吸入治疗小儿毛细支气管炎的疗效探讨

目的:探讨γ-干扰素联用α-细辛脑雾化吸入治疗小儿毛细支气管炎的疗效。方法:对确诊的120例患毛细支气管炎患儿随机分为4组,每组30例。γ-干扰素治疗组应用γ-干扰素0.5×105IU/次,加入生理盐水10 ml中雾化吸入;α-细辛脑组应用α-细辛脑4 mg/次加入生理盐水10 ml中雾化吸入;γ-干扰素联用α-细辛脑组联用以上两种方法,先吸入γ-干扰素。生理盐水对照组仅雾化吸入生理盐水10 ml,以上治疗均每日2次。结果:4种治疗方案中,γ-干扰素联用α-细辛脑组疗效最好,γ-干扰素组及α-细辛脑组均有效,优于生理盐水对照组,患儿气促、肺部音的消失时间以及住院时间均缩短。结论:联合α-细辛脑及γ-干扰素治疗小儿毛细支气管炎效果好。     

氧驱动雾化与空气压缩泵雾化吸入治疗毛细支气管炎的护理观察

目的比较氧驱动雾化与空气压缩泵雾化治疗毛细支气管炎的疗效与优缺点,探讨毛细支气管炎的最佳吸入方法。方法将2011年11月至2012年2月住院的93例,毛细支气管炎患儿随机分为对照组39例和观察组54例,在治疗相同的基础上,观察组采用布地奈德1mg,特布他林2．5mg氧驱动雾化,每天二次,对照组采用空气压缩泵雾化吸入相同的药物和次数。结果以患儿临床症状改善为依据,观察组有效率87％,对照组有效率71．8％。结论氧驱动雾化吸入治疗效果优于空气压缩泵雾化,并提高血氧饱和度,是目前治疗毛细支气管炎的首选方法。     

氧驱动雾化吸入氨溴索辅助治疗毛细支气管炎疗效观察

目的 探讨氧驱动雾化吸入氨溴索辅助治疗毛细支气管炎临床效果.方法 将52例毛细支气管炎惠者随机分为治疗组和对照组各26例,对照组常规给以抗感染、平喘、糖皮质激素等基础治疗;治疗组在常规治疗的基础上给以盐酸氨溴索注射液15mg加入生理盐水2ml氧驱动雾化吸入,每日2次,疗程7天.结果 治疗组患者咳嗽及肺痰鸣青持续时间明显短于时照组(P<0.05);憋喘、哮鸣音和治愈时间显著短于对照组(P<0.01).结论 氨溴索氧驱动雾化吸入治疗毛细支气管炎可明显提高疗效,缩短治疗时间.     

干扰素及布地奈德雾化吸入治疗毛细支气管炎疗效观察

目的：观察α-2b干扰素、布地奈德雾化吸入治疗毛细支气管炎的疗效。方法：毛细支气管炎患儿87例,被随机分成两组,治疗组43例,对照组44例,对照组给予静脉应用地塞米松、病毒唑、吸氧、止咳化痰、退热等对症处理;治疗组在上述基础上给予氧驱动雾化吸入干扰素和布地奈德。结果：治疗组在咳嗽、喘憋、肺部哮鸣音消失的时间、胸部x线等恢复时间快于对照组。结论：a-2b干扰素、布地奈德雾化吸入治疗毛细支气管炎有效。     

普米克联合运德素氧驱动雾化吸入治疗毛细支气管炎的疗效观察

目的:了解布地奈得(普米克)和运德素(α干扰素)氧驱动雾化吸入对小儿毛细支气管炎的疗效。方法:我院于2010年1月-2012年1月对173例毛细支气管炎患儿分对照组及治疗组。两组均给予综合治疗,治疗组在此基础应用普米克加运德素氧驱动雾化吸入治疗。结果:治疗组显效率明显高于对照组,症状消失时间及住院天数均较对照组缩短,未见明显不良反应。结论:普米克加运德素氧驱动雾化吸入治疗毛细支气管炎可减轻喘憋症状,缩短住院时间,疗效显著、安全,值得推广使用。     

氧气驱动雾化吸入α-干扰素治疗毛细支气管炎的疗效观察

目的观察氧气驱动雾化吸入α-干扰素对小儿毛细支气管炎的疗效。方法 2011年10月至2012年3月对69例毛细支气管炎患儿应用氧气驱动雾化吸入α-干扰素治疗。结果治疗组显效率明显高于对照组(P<0.05),症状消失时间及住院天数均较对照组缩短,未见明显不良反应。结论氧气驱动雾化吸入α-干扰素治疗毛细支气管炎可减轻患儿咳嗽、喘憋等呼吸道症状,缩短住院时间,疗效显著,值得推广应用。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Dr.Zhang Ren's Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.