A case of Poncet’s disease: retroperitoneal tuberculous lymphadenitis and polyarthritis

To the editor： Reactive arthritis （ReA） in tuberculosis （TB） is known as Poncet＇s disease. It is a rare aseptic form of arthritis observed in patients with active TB. It has been suggested that Poncet＇s disease mainly occurs in patients with extrapulrnonary TB. We report here a case of Poncet＇s disease in a patient with retroperitoneal tuberculous lympbadenitis.     

Macronutrients and Health—Steps to Ameliorating the Nutrition transition Trap

Countries that have made the health transition from a communicable disease base to a non-communicable disease base find themselves gripped in an epidemic of wealth created diseases mediated by altered macronutrient intakes,energy intakes and reduction in physical activity.Avoiding the negative impact of the nutrition transition while accepting the positive aspects of the wealth transition can best be achieved by focussing on publicising the benefits of a low fat diet in the context of an active lifestyle.How this is achieved should reflect ecologically sound food production appropriate to national needs.Countries that achieve this will be in the best position to capitalize on the reduction in communicable disease rates without causing a rise in non-communicalble disease rates.     

Observation and Mechanism Exploration of Acupuncture on body Weight Reduction

Simple obesity is a disease of overweight caused by fat accumulation in the body due to higher calorie intake far exceeding the consumption. 1 WHO in 1997 had declared that obesity, as a disease, is a main dangerous factor of hypertension, coronary heart …     

Impact of Absolute Humidity and Temperature on Eczema

Eczema is a common dermatological disease with a prevalence of 15%–30%among children and up to 10%among adults,causing great disease burden worldwide[1].Meteorological factors play important roles in the development of eczema.For instance,a U.S.cohort study in children indicated that the odds of poorly controlled eczema increased by 15%for every 5°F increase in temperature and that the odds of poorly controlled eczema increased by 10%for every 10%increase in relative humidity(RH)[2].     

Pharmacological intervention of hypertension in proteinuric chronic kidney disease： how and what？

Chronic kidney disease （CKD） is a significant interactive disease in patients with diabetes, hypertension, and cardiovascular disease with major morbidity consequences and high costs to the healthcare system. The prevalence of end stage renal disease （ESRD）, a f＇mal outcome of CKD, has increased progressively in the past decades in both developing and developed countries. It is now appreciated that the majority of patients with CKD have a chronic decline of renal function over years before renal replacement therapy is required. This non-specific process continues even when the initial insult is no longer present and has been called progression of CKD.     

Analysis of Health Service Utilization and its Influencing Factors among Patients with Pneumoconiosis in China

Pneumoconiosis,an interstitial lung disease that occurs from breathing in certain kinds of damaging dust particles,is a major occupational disease in China.Patients diagnosed with occupational pneumoconiosis can avail of free medical treatment,whereas patients without a diagnosis of occupational diseases cannot not claim free medical treatment in most provinces from the government before 2019.This study aimed to analyze the priority of medical facility selection and its influencing factors among patients with pneumoconiosis.     

Effect of Sodium Nitrite on Myocardial Glutathione Peroxidase and Protective Action of Vitamin E and Selenium

Under the condition of acute NaNO_2 poisoning, the changes of myocardial GSH-Px activity of rats fed a diet composed of grains grown in the endemic region of Keshan disease and the same diet with supplementation of vitamin E or selenium were investigated. By gavage of toxic doses of NaNO_2, the myocardial GSH-Px was significantly reduced (P<0.05). Vitamin E or selenium supplementation protected the enzyme activity from reducing. It is suggested that the simultaneous action of an increase in selenium and vitamin E intake and a decrease in nitrite intake might greatly prevent the occurrence of Keshan disease.     

Comparison of CT and Fiberoptic Bronchoscopy in the Evaluation of Bronchial Disease

CT was compared to FB in 51 cases to study the value of CT for visualizing bronchial disease. CT finding was positive in 46 of 51, and suggested CT was closely correlated with FB. 3 of 5 with false negative were endobronchial lesions, 2 were submacosal diseases. By camparison, it was found conventional tomography was a useful method in diagnosing the bronchial disease.     

Aortopulmonary window： a case diagnosed and surgery confirmed by ultrafast computed tomography

Aortopulmonary window (APW) is a rare congenital defect,found in 0.2% of patients with congenital heart disease,in which a communication exists between the ascending aorta and the pulmonary artery trunk with normal separation of the aortic and pulmonary valves.     

Atrial fibrillation and rheumatic valvular heart disease:usefulness of very-low-dose amiodarone

Atrial fibrillation (AF) is frequently associated with rheumatic valvular heart disease (RVHD). AF leads to systemic thromboembolic complications, reduced quality of life (QOL), impaired ventricular function and also increased mortality. Multivariate analysis of results from a population-based study has shown that valvular heart disease is one of risk factors for development of AF.1 The frequency of RVHD has decreased in developed countries in recent years, but RVHD now constitutes a s…     

The Present State and Perspective in Treatment of Primary Osteoporosis by Acupuncture and Moxibustion

Primary osteoporosis, a commonly encounteredmetabolic bone disease in the postmenopausalwomen and the aged people,can be classified bymodem medicine into postmenopausal osteoporosis(Type I)and senile osteoporosis (Type Ⅱ).The     

Paget＇s Disease is Associated with Eleven Cancerous Regions： a Case Report and Therapeutic Strategy

Paget＇s disease of the breast is an uncommon disorder that accounts＇for 1% to 3% of all mammary tumors. The incidence of underlying carcinoma associated with Paget＇s disease has been reported in 82% to 100% of cases. The finding of underlying carcinoma reaches almost 100% when a palpable lump is also present. In this rare case, we described a patient presenting with Paget＇s disease but no palpable lump. However, we found 11 independent regions which were all invasive ductal carcinoma after the operation. Considering this patient, we should pay more attention to a multifocal and multicentric breast carcinoma associated with Paget＇s disease. Furthermore, we believe the mammography examination and a modified radical mastectomy are the most appropriate treatments for this population in clinical practice.     

Present Situation and Prospects of TCM Treatment of Parkinson＇s Disease

Parkinson‘s disease (PD) is a chronic degenerative disease of the nervous system marked by tremor, muscle rigidity, hypokinesis, abnormal posture, and pathologically, selective loss of dopaminergic neurons in the substantia nigra of the midbrain and obvious decrease of dopamine content in the striatum It is encountered mostly in the middle-aged and old persons and is one of main causes inducing their deformity.     

Current and Future Therapeutic Agents in the Man—agement of Heart Failure

Congestive heart failure is a disease in which initially compensatory changes in car-diac, vascular, and renal functions become detrimental over time. The changes are mediated bg a largenumber of neurohormones and cytokines. Counter-regulatory hormones also play a role, but are general-ly insufficient to offset the adverse effects of the neurohormones or progression of the disease. Symp-toms of heart failure occurs in the presence of systolic dysfunction, usually documented by a decrease inejection fraction, or can present with impaired diastolic function occasionally labeled as heart failurewith preserved systolic function of the left ventricle. Heart failure and its treatment represent a medicalproblem of significant importance because of the high mortality associated with it despite the current ther-apy, which has substantial evidence of reduction in mortality and morbidity. Prevention or slowing of theprogressive deterioration in function of the heart and other organs involved through utilizing new     

Prevalence and risk factors of atrial fibrillation in preterminal inpatients aged 60 years and over

Background Atrial fibrillation is a common arrhythmia and a major risk factor for ischaemic stroke. We investigated the prevalence of atrial fibrillation and its relation to age, gender and underlying heart disease in patients aged 60 years and over who died during hospitalization.
Methods Between 1955 and 2005, 1519 autopsies of in-hospital deaths in Beijing Hospital were performed. Among them, 540 cases met criteria of age ≥60 years and full clinical history including electrocardiogram, echocardiogram, myocardial perfusion images and detailed cardiac pathology records from autopsy.
Results Atrial fibrillation occurred in 193 of 540 patients and prevalence increased with age （10.5% in patients younger than 60 years, 39.6% （80-89 years） and 54.8% （≥ 90 years）） being higher in patients with underlying heart disease than without heart disease （P 〈0.0001）. Coronary artery disease （CAD）, congestive heart failure, cardiac valve dysfunction and chronic renal failure were associated with a higher prevalence of atrial fibrillation （P 〈0.001）. CAD with anterior myocardial infarction or left anterior descending artery disease was also associated with an increased prevalence of atrial fibrillation （P 〈0.05）. Following autopsy, clinical misdiagnosis of CAD increased with age and missed clinical diagnosis of CAD decreased with age. Multivariate Logistic regression analysis revealed independent predictors of atrial fibrillation： age （OR=1.335, 95% CI： 1.114-1.600, P 〈0.0001）, underlying heart disease （OR=2.019, 95% CI： 1.244-3.278, P 〈0.005）, chronic heart failure （OR=1.873, 95% CI： 1.272-2.757, P 〈0.005）, mitral regurgitation （OR=2.163, 95% CI： 1.093-4.278, P 〈0.05） and mitral stenosis （OR=33.575, 95% CI： 2.852-395.357, P 〈0.05）.
Conclusions A high prevalence of atrial fibrillation was found in Chinese patients ≥60 years who died in hospital, especially when associated with underlying heart disease. The independent risk factors of atrial fibr     

Effects of Acupuncture and Moxibustion on Tear-film of the Patients with Xerophthalmia

Xerophthalmia is a disease with uncomfortable sensation in eyes caused by instability of tear-film and damage to the ocular surface due to abnormality     

Treating Cerebral Vascular Diseasewith Rational Medication of IntegrativeChinese and Western Medicine

Cerebral vascular disease(CVD)also called thecerebral stroke or windstroke.There are twocommon types in clinic,that is,thrombotic CVDand hemorrhagic CVD.CVD has both a high incidence rate and a high mor-tality rate.It has become     

A novel deletion mutation of ATP7A gene in a Chinese family with Menkes disease

Menkes disease is a rare X-linked recessive .hereditary disorder first described by Menkes et al in 1962.1 including The gene mutation results in clinical features pili torti, unusual facies, mental/growth retardation and metabolic dysfunction. The pathogenic gene ATP7A was identified in 1993.2 It is located on chromosome X and encodes a transmembrane Cu^2＋ transporter. Here we reported the clinical manifestations and results of genetic study of a family with Menkes disease. In this family, a deletion mutation in ATP7A gene is responsible for the disease.     

Restrictive fragment length polymorphisms of markers 3''HVR and 24-1 and their applications in gene diagnosis of adult polycystic disease in Chinese.

Adult polycystic kidney disease was diagnosed with pedi-gree analysis using polymorphic DNA markers linked to thedisease gene in 5 families. The markers were thoroughly charac-terized in the population. We noted two important markers,3'HVR and 24-1, which flank the disease gene PKD1 in nor-mal Chinese. Southern hybridization was used, and numerous3'HVR / Pvull polymorphic allelic bands varied from 1.4 kb to8.0 kb with a positive skew distribution. They were divided into11 groups with an interval of 0.6 kb and a heterozygosity ratcof 0.86. Allele frequencies were observed. When the probe24-1 was hybridized with genomic DNA digested by TaqI, twoalleles, B1 and B2, were detected with frequencies of 0.76 and0.24, respectively. B1 was 3.8 kb in size and B2 was composedof 2 bands, 1.5 kb and 1.3 kb. The polymorphism informationcontent was found to be 0.297. Using these two markers forlinkage analyses of 5 affected families, we confirmed thelinkage between 3'HVR and the disease gene PKDI and madepresymptomatic