硅胶带额肌悬吊术治疗先天性睑裂狭小症

硅胶带额肌悬吊术治疗先天性睑裂狭小症广州部队武汉总医院眼科金中秋，韩苏宁，尹禾先天性睑裂狭小症是一种常染色体显性遗传病，临床表现为先天性上睑下垂、倒向性内毗赘皮、睑裂小及两眼内眦距离增宽。对于本症的治疗，实际包括内眦远距及内眦赘皮的矫正，外眦成形及上...     

一次手术矫正睑裂狭小综合征的临床观察

目的 探讨睑裂狭小综合征简单易行的一次手术治疗方法。方法 对睑裂狭小综合征设计并临床应用内外眦成形术、上睑下垂矫正术一次完成的治疗方法，施行手术22例。术后平均观察11.6月。结果 治愈17例，显效2例，改善3例，无复发，无并发症出现，手术效果良好，有效率达100%。结论 一次完成矫正睑裂狭小综合征是一种安全可靠的方法。     

介绍一种治疗先天性睑烈狭小缝合征的手术(摘要)

先天性睑裂狭小综合征Blepharophimosis Syndrome是一种常染色体显性遗传病,临床上有四大特征;先天性上睑下垂、倒向性内眦赘皮、睑裂缩小及两眼内眦距离增宽。我院于90年2月采用日本内田氏手术矫治一例,效果良好。患者女,13岁,自出生即发现双眼上睑下垂。检查:双眼内眦赘皮,上睑下垂,上睑缘遮盖瞳孔约1mm,去除额肌作用后,双上睑均无提上睑运动,双睑裂水平径22mm,垂直径4mm,双眼内眦距离41mm。诊断:双眼睑裂狭小综合征。手术方法:将国外二期手术改为一期手术。即内田氏内外眦成形术与上睑下垂阔筋膜悬吊术同时进行。(1)内眦部手     

先天性睑裂狭小综合征28例临床分析

先天性睑裂狭小综合征２８例临床分析陈绮龄先天性睑裂狭小综合征临床表现为先天性小睑裂、睑下垂、内眦赘皮及两内眦间距离增宽等四联征。１８７５年由Ｇａｌｅｚｏｗｓｋｉ首先报告，１９２１年Ｋｏｍｏｔｏ详细描述，故也称Ｋｏｍｏｔｏ综合征。现将我院收治的２８例（...     

先天性睑裂狭小综合征一家系

先天性睑裂狭小综合征亦称先天性小睑裂，是一种常染色体显性遗传病。在我院就诊患者中发现一家系，报告如下。     

先天性小睑裂综合征家系分析及手术治疗

0引言先天性小睑裂综合征(congenital blepharophimosis syndrome),又称睑裂狭小-上睑下垂-倒向型内眦赘皮综合征(blepharophimosis-ptosis-epicanthus inversus syndrome,BPES)和小睑裂畸形,是一种少见的常染色体显性遗传病。临床表现为睑裂狭小,上睑下垂,反向内眦赘皮,内眦间距增宽。本文对一组先天性小睑裂综合征病例进行家系分析,全部采用同期手术治疗方法,有效地改善了患者外观,取得满意效果。1临床资料本组患者为2008/2010年在我院眼科病房收治的20例小睑裂综合征,其中男10例,女10例,计40眼。     

先天性睑裂狭小综合征二例手术治疗的疗效观察

先天性睑裂狭小综合征又名倒置性内眦赘皮—眼裂狭小—上睑下垂综合征。最近我院收治了2例,分别分期进行了手术治疗,手术效果尚好,现报导如下。     

家族性先天性睑裂狭小综合征

0引言先天性睑裂狭小综合征（congenital blepharophimosis syndrome）是一种先天异常,又称睑裂狭小-上睑下垂-倒向型内眦赘皮综合征（blepharophimosis-ptosis-epicanthus inversus syndrome,BPES）[1],以睑裂狭小为特征,     

改良Y-V成形及额肌瓣悬吊治疗小睑裂综合征

目的 探讨小睑裂综合征的临床特点及手术效果。方法 回顾性分析我院2002年3月至2006年7月间收治的小睑裂综合征15例。结果术后随访3～36个月,Y-V成形及额肌瓣悬吊Ⅰ期手术治疗的15例患者,术后睑裂长度平均增长3～5mm;睑裂宽度增大3～6mm;双眼内眦间距缩短7～12mm。结论 改良Y-V成形及额肌瓣悬吊Ⅰ期手术治疗小睑裂综合征患者效果肯定。小睑裂综合征患者应尽早手术治疗。     

先天性小睑裂综合征一期矫正术五例报告

先天性小睑裂综合征是较少见的先天性畸形,是一种常染色体显性遗传病.临床主要表现为先天性上睑下垂、倒向性内眦赘皮、睑裂狭小及两眼内眦间距增宽.目前,国内矫正此病方法甚多,但需多次手术才能达到改善面容之目的.我科2001年以来对5例额肌肌力正常,而提上睑肌肌力小于4mm的先天性小睑裂综合征患者采用一期手术矫正,达到了理想效果,现报告如下.     

Strabisme Alternant - Etude clinique - traitement

The author defines motor and sensory alternation: the term alternation should not be used in isolation, it should always be accompanied by the name of the parameter concerned. Sensory alternation is always found together with motor alternation but the reverse is not true.The examining criteria for a diagnosis of sensory alternation are given, sensory alternation must not be confused with alternating inhibition. Working from clinical observations of cases of motor alternating strabismus, the author selects 2 types of binocular sensory relations which allow one to differentiate between:- cases of primary alternating strabismus- cases of secondary alternating strabismusThese forms will develop in different ways; in both cases a cure is possible providing that the right treatment is prescribed and once prescribed carefully followed, etc. It is always a case of serious forms of strabismus whose developmental period is spread over several years.According to the authors, the frequency of cases of true primary strabismus is from 1–3%, the frequency of cases of secondary alternating strabismus varies according to the type of therapy practised on cases of monocular strabismus with amblyopia. These latter will become cases of alternating strabismus under the influence of certain types of therapy carried out over several years (penalization, rocking, alternated occlusion, etc...).Experimental data on kittens confirm clinical data; kittens placed in abnormal environments during the sensitive period will show modification in the distribution of cortical cells and the absence of binocular cells (either because the excitation of the two eyes was not simultaneous, or not identical: artificial strabismus, occlusion, opaque glasses). This disturbances become irreversible after a certain period of exposure (a function of age, length of exposure, etc...).It is thus necessary to bear in mind: 1) the iatrogenic risks of certain orthoptic treatments, 2) the necessity for a binocular form of treatment as soon as possible, as once a certain stage is passed, cortical plasticity diminishes and the elaboration of normal binocular relations becomes impossible.

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Effects of Adenosine Agonists on Intraocular Pressure and Aqueous Humor Dynamics in Cynomolgus Monkeys

The effects of single or multiple topical doses of the relatively selective A₁adenosine receptor agonists (R)-phenylisopropyladenosine (R-PIA) and N⁶-cyclohexyladenosine (CHA) on intraocular pressure (IOP), aqueous humor flow (AHF) and outflow facility were investigated in ocular normotensive cynomolgus monkeys. IOP and AHF were determined, under ketamine anesthesia, by Goldmann applanation tonometry and fluorophotometry, respectively. Total outflow facility was determined by anterior chamber perfusion under pentobarbital anesthesia. A single unilateral topical application of R-PIA (20–250 μg) or CHA (20–500 μg) produced ocular hypertension (maximum rise=4.9 or 3.5 mmHg) within 30 min, followed by ocular hypotension (maximum fall=2.1 or 3.6 mmHg) from 2–6 hr. The relatively selective adenosine A₂antagonist 3,7-dimethyl-1-propargylxanthine (DMPX, 320 μg) inhibited the early hypertension, without influencing the hypotension. Neither 100 μg R-PIA nor 500 μg CHA clearly altered AHF. Total outflow facility was increased by 71% 3 hr after 100 μg R-PIA. In conclusion, the early ocular hypertension produced by topical adenosine agonists in cynomolgus monkeys is associated with the activation of adenosine A₂receptors, while the subsequent hypotension appears to be mediated by adenosine A₁receptors and results primarily from increased outflow facility.