阿昔洛韦联合光子氧透射液体疗法治疗老年带状疱疹疗效观察

目的 :评价阿昔洛韦联合光子氧透射液体疗法治疗老年带状疱疹的疗效和安全性。方法 :60例老年带状疱疹患者随机分为两组 ,阿昔洛韦与光子氧透射液体疗法为联合治疗组 ,单纯阿昔洛韦为对照组 ,疗程共 7天 ,并观察疗效及不良反应。结果 :联合治疗组治疗老年带状疱疹止痛、结痂时间均显著低于对照组 (P <0 0 1 ) ,后遗神经痛发生率明显降低 (P <0 0 5 )。结论 :阿昔洛韦联合光子氧透射液体疗法治疗老年带状疱疹起效快 ,并且能有效缩短病程 ,降低后遗神经痛的发生率。     

光子嫩肤技术治疗92例面部色素性皮肤病的临床观察

目的研究光子嫩肤技术对面部色素性皮肤病治疗效果。方法应用光子多功能治疗仪治疗92例面部色素性皮肤病,并进行临床观察。结果雀斑47例,有效率95.7%;痤疮后色素沉着22例,有效率95.5%;黄褐斑11例,有效率18.2%;脂溢性角化12例,有效率58.3%。结论光子嫩肤技术适合治疗雀斑和痤疮后色素沉着。     

微波治疗13种皮肤病212例疗效观察

目的：探讨微波手术治疗仪在皮肤病中的临床应用及治疗疗效。方法：应用MTC-EX型微波手术治疗仪，治疗13种皮肤病212例，判定其疗效。结果：212例1次治愈195例，占92．0％；2次治愈12例，占5．7％；3次治愈2例，占0．9％；痊愈209例，总有效率98．6％。结论：微波手术治疗，是继电灼、冷冻、激光之后的一种高新技术，是目前治疗皮肤病较为理想的手术治疗方法。     

光量子氧透射治疗仪治疗皮肤病的疗效观察

光量子氧透射液体疗法是在光量子血液疗法基础上发展起来的一种全新疗法。该疗法的基本原理和光量子血液疗法一样,采用光量子氧透射治疗仪、一次性石英玻璃输液器。 我们用光量子氧透射治疗仪治疗皮肤病     

国外皮肤病治疗速报

国外皮肤病治疗速报本文综合了１９９３年８月～１９９３年１１月部分国外期刊发表的皮肤病治疗方面的报道。银屑病焦油用于治疗银屑病已几个世纪了，尽管其应用广泛，几乎没有证据支持单纯应用焦油的临床效果。传统观点认为应用焦油的精制成分如煤焦油溶液和液体碳去污剂...     

妊娠期皮肤病

女性在妊娠期间易于发生多种皮肤病，正确的诊断和分类对这些疾病必要时的治疗是必不可少的。该文将妊娠期皮肤病分为3类：①皮肤的生理性变化，②受妊娠影响的皮肤病和皮肤肿瘤，③妊娠期特有的皮肤病。并简单介绍常见妊娠期皮肤病的病因、临床表现、诊断及治疗。     

668例颜面部皮肤病的微波美容治疗

本文就采用ＭＴＣ－３型微波手术器治疗６６８例１４种面部皮肤病的临床观察，总结了该仪器利用微波辐射治疗皮肤病的效果，认为其优点在于操作简便、术中不出血、手术时间短、术后不易感染、愈合快等。优于液氮冷冻及ＣＯ２激光治疗，是美容治疗颜面部表性皮肤病的较新理想手段。     

第三届全国皮肤美容激光与光子学习班暨首届中国医学科学院皮肤美容激光年会

为推广我国皮呋美容激光与光子治疗技术，中国医学科学院皮肤病研究所将于2007年6月举办第三届全国皮呋美容激光与光子学习班，届时将邀请周内相关专家就美容激光与光子的基础、临床和治疗技巧等进行系统的讲座。同时举办首届中国医学医学院皮肤美容激光与面部美容外科年会，中国医学科学院协和医院、整形医院、皮肤病医院将分别介绍自己的治疗经验和教洲．会泌期间将邀请幽内外专家介绍美容激光新技术及发展趋势，同时设立皮肤血管性疾病治疗、光动力学治疗专题讲座，欢迎来函索取课程信息.[第一段]     

常见皮肤病电离子治疗机治疗与术后护理的体会

常见皮肤病电离子治疗机治疗与术后护理的体会李玉娟郭静我科于１９９５年底至今应用ＧＸ Ⅱ型多功能电离子治疗机（广西科学院应用物理研究所生产）治疗１０余种皮肤病近７００例，取得良好效果，现报告如下。治疗方法常规消毒，局部浸润麻醉或１％地卡因表面麻醉（肛门...     

全国皮肤激光与光子学习班暨江苏省美容主诊医师（美容皮肤科）培训班通知北大核心CSCD

由中国医学科学院皮肤病医院激光科主办的全国皮肤激光与光子学习班暨江苏省美容主诊医师（美容皮肤科）培训班定于2013年8月13—17日在南京举行。授课内容为激光与光子医学理论、激光与光子治疗进展、激光磨削术在临床应用及理论基础、光子嫩肤治疗基础及临床适应证、色紊性疾病和血管性疾病的治疗、激光脱毛治疗及白癜风和痤疮的光学治疗、痤疮的治疗进展等。届时将邀请国内该领域的知名专家授课、答疑,学习期满,授予国家继续医学教育一类学分10分,并颁发培训证书。诚邀江苏省内外从事激光美容、美容皮肤科及美容中医科医师参加。联系人：史华玲、王娟;电话：025—85412124,85478000;Email：pysjgk@sina．     

Hyperbaric oxygen therapy: An alternative treatment for radiation‐induced cutaneous ulcers

Radiotherapy is a widely recognised treatment for non‐melanoma skin cancer. We report three cases of radiation‐induced skin ulcers in which hyperbaric oxygen therapy was administered in 90‐min sessions, 5 days a week at 2.4 absolute atmospheres in a multiplace hyperbaric chamber. Hyperbaric oxygen therapy is an outpatient treatment that does not displace other classical treatments and may be used as an adjunct therapy.     

Incidence of side effects after laser hair removal

BACKGROUND: Despite the widespread use of lasers for hair removal there are few data published on the incidence of side effects from this treatment. OBJECTIVE: The aim of this study was to generate data on a large number of patients receiving laser hair removal to obtain an accurate assessment of the incidence and type of side effects resulting from treatment. METHODS: A multicenter prospective study of patients presenting for laser hair removal was conducted to determine incidence of side effects in relation to skin type and laser or lasers used. RESULTS: Laser hair removal is associated with a low incidence of side effects that are self-limiting in the majority of cases. The highest incidence of side effects was seen in patients with darker skin treated with the long-pulsed ruby laser. CONCLUSIONS: Laser hair removal is inherently safe. For darker Fitzpatrick skin types the long-pulsed neodymium:yttrium-aluminum-garnet laser is preferred to the ruby laser.     

UVA1 phototherapy: a review of mechanism and therapeutic application

Ultraviolet radiation (UVR) phototherapy has been associated with both deleterious and beneficial effects to patients with both localized and systemic skin disorders. Phototherapy is advantageous in diseases of the epidermis and dermis, as it provides the most direct approach minimizing systemic side effects. Most recently, ultraviolet A1 (UVA1) phototherapy has emerged as a specific UVR phototherapeutic mechanism. It has shown to be therapeutic in a number of sclerosing skin conditions and other dermatitides, in many cases proving to be more effective than other phototherapy modalities. Treatment advantages of UVA1 phototherapy include the ability to penetrate into the deep layers of the skin to affect changes on disease‐causing T cells, as well as activation of endothelial cells to promote neovascularization. UVA1 therapy also has been shown to be relatively free of side effects associated with other phototherapy regimens, including erythema and cellular transformation. These properties make UVA1 phototherapy an important treatment option for many debilitating skin conditions.     

Optical coherence tomography in dermatology: a review

Background/aims: Optical coherence tomography (OCT) is a non‐invasive technique for morphological investigation of tissue. Since its development in the late 1980s it is mainly used as a diagnostic tool in ophthalmology. For examination of a highly scattering tissue like the skin, it was necessary to modify the method. Early studies on the value of OCT for skin diagnosis gave promising results. Methods: The OCT technique is based on the principle of Michelson interferometry. The light sources used for OCT are low coherent superluminescent diodes operating at a wavelength of about 1300 nm. OCT provides two‐dimensional images with a scan length of a few millimeters (mm), a resolution of about 15 μm and a maximum detection depth of 1.5 mm. The image acquisition can be performed nearly in real time. The measurement is non‐invasive and with no side effects. Results: The in vivo OCT images of human skin show a strong scattering from tissue with a few layers and some optical inhomogeneities. The resolution enables the visualization of architectural changes, but not of single cells. In palmoplantar skin, the thick stratum corneum is visible as a low‐scattering superficial well defined layer with spiral sweat gland ducts inside. The epidermis can be distinguished from the dermis. Adnexal structures and blood vessels are low‐scattering regions in the upper dermis. Skin tumors show a homogenous signal distribution. In some cases, tumor borders to healthy skin are detectable. Inflammatory skin diseases lead to changes of the OCT image, such as thickening of the epidermis and reduction of the light attenuation in the dermis. A quantification of treatment effects, such as swelling of the horny layer due to application of a moisturizer, is possible. Repeated measurements allow a monitoring of the changes over time. Conclusion: OCT is a promising new bioengineering method for investigation of skin morphology. In some cases it may be useful for diagnosis of skin diseases. Because of its non‐invasive character, the technique allows monitoring of inflammatory diseases over time. An objective quantification of the efficacy and tolerance of topical treatment is also possible. Due to the high resolution and simple application, OCT is an interesting addition to other morphological techniques in dermatology.     

基于纳米载体的局部给药系统治疗皮肤病的研究进展

局部给药是治疗皮肤相关疾病的重要给药途径。然而,受皮肤角质层天然屏障的影响,外用制剂如软膏或乳膏往往达不到理想的效果,甚至伴随不良反应。近年来,随着纳米材料研究的日益成熟,新型的以纳米材料为载体的外用制剂越来越多地被应用到皮肤病的治疗领域中。该综述具有代表性的用于皮肤靶向应用的纳米给药系统的研究进展。     

Use of psychotropic drugs in the dermatology patient: When to start and stop?

Dermatologists often find themselves treating patients with psychiatric disorders, most commonly anxiety and depression, in the context of skin disease. The psychiatric condition may either be present before the skin condition developed and exacerbate it or, in some cases, even create it (eg, delusions of parasitosis). Alternatively, the psychiatric condition may occur subsequent to the development of the dermatologic condition. The treatment of psychodermatogic disorders requires collaboration between psychiatrists and dermatologists. Dermatologists should be able to recognize primary psychiatric disorders and refer patients to psychiatrists for appropriate treatment; however, the patient may encounter delays in accessing psychiatric care, and dermatologists should be familiar with the basic use of psychotropic drugs. This review describes common psychiatric disorders encountered in a dermatology practice and their treatment with psychotropic drugs. For each commonly used drug, dose range, side effects, and how to initiate and terminate treatment are described. Although psychotherapy is an important part of the treatment of most psychiatric disorders, we have limited our focus to psychotropic drugs in this review.     

Present status of eyelid phototherapy. Clinical efficacy and transmittance of ultraviolet and visible radiation through human eyelids.

BACKGROUND: Phototherapy for the eyelid has not previously been recognized as a safe and effective treatment of photoresponsive dermatoses of the eyelid, such as atopic dermatitis, vitiligo, psoriasis, lymphomatoid papulosis, and parapsoriasis. OBJECTIVE: The purpose of this study was to demonstrate the efficacy and safety of this treatment. METHODS: Two cases are presented to demonstrate clinical efficacy. In addition, a retrospective eye evaluation of seven patients receiving a combined total of greater than 1300 eyelid phototherapy treatments was performed. To determine whether potentially harmful UV radiation is significantly transmitted through eyelid skin, an in vitro study was conducted to measure the percentage transmittance of ultraviolet-visible radiation through five excised eyelids. RESULTS: In the two cases presented, remarkable improvement occurred without adverse side effects, suggesting that it is possible to deliver incremental UV dosages to eyelid skin to achieve clearing of skin disease. Retrospective analysis of patients' records revealed no ocular disease from the phototherapy. In vitro eyelid examination produced data that indicated negligible quantities of UV radiation were transmitted through eyelid skin compared with the visible spectrum, in which up to 77% of the radiation was transmitted through the tissue. CONCLUSION: The combined clinical experience and transmittance data suggest that eyelid phototherapy is a safe and effective treatment in selected patients.     

毛发生长周期中维A酸合成相关蛋白及受体的研究

脊椎动物可南食物摄取的维生素A体内合成维A酸,参与多个系统细胞的生长与分化,尤其是表皮细胞的分化.维A酸类药物系统用于皮肤疾病的治疗已较为成熟,在产生疗效的同时,也可H{现多种不良反应,弥漫性脱发为其中之一,机制不清楚.近年来有学者研究小鼠体内维A酸相关蛋白在毛发生长周期的不同时期毛囊各部位细胞中的免疫定位,对维A酸引起脱发机制的研究有一定的提示.     

Hautschäden nach akuter Strahlenexposition mit ionisierender Strahlung

The cutaneous radiation syndrome includes all deterministic effects on the skin and visible parts of the mucosa from ionizing radiation. The Intensity and duration of radiation-induced skin symptoms depend on the kind and quality of ionizing radiation. The aim of this study was the investigation of the importance of the time of the development of radiation induced-skin effects on the prognosis of radiation accident victims. Clinical data about radiation accident victims from the database SEARCH were used. 211 cases with good documentation regarding radiation-induced skin effects were selected. From these 211 patients, 166 survived the acute phase of the acute radiation syndrome, while 45 died during the acute phase. Among those patients who did not survive the acute phase, 82.2?% showed their first documented radiation-induced skin symptoms during the first 3 days after radiation exposure. Of those patients whose first documented radiation-induced skin symptoms appeared on or after day four, 94.2?% survived the acute phase. The time to the occurrence of the first radiation-induced skin effects is diagnostically significant. The skin plays an important role in the clinical course of radiation syndromes and in the development of radiation-induced multi-organ failure. In a retrospective data analysis like this, the quality of data might be a limitation.     

Narrow‐band ultraviolet B as a potential alternative treatment for resistant psychogenic excoriation: an open‐label study

Narrow‐band ultraviolet therapy has been used successfully for the treatment of inflammatory skin disorders and generalized pruritus. We have prospectively evaluated seven consecutive patients with resistant psychogenic excoriation (PE) treated with narrow‐band ultraviolet B (NB‐UVB). Approximately 70% of all patients showed improvement in their condition. NB‐UVB therapy was well tolerated, with no serious side effects. We may conclude that, when treating a patient with PE, NB‐UVB in combination with other approaches may provide extra benefit in resistant cases.