微创治疗复发性髌骨脱位的治疗效果和护理干预

目的:为了进一步提高我院治疗复发性髌骨脱位的临床治疗效果,本文就微创治疗复发性髌骨脱位的治疗效果和护理干预内容进行了浅显的研究和探讨。方法:将我院在2011年10月至2012年10月期间收治的120例复发性髌骨脱位患者随机分为观察组和对照组,两组患者各60例,给予对照组患者常规用药治疗,给予观察组患者进行微创治疗,对两组患者的治疗效果进行观察和统计。结果:观察组患者的治疗效果要明显优于对照组,两组之间的差异显著(P0.05)。结论:微创治疗复发性髌骨脱位的临床效果十分理想,有效的提高了临床治疗效果,减轻了疾病对患者造成的伤害,值得推广。     

肝硬化腹水内科综合治疗临床分析

目的：针对肝硬化腹水的内科综合治疗方法进行分析,并观察其治疗效果。方法回顾性分析30例肝硬化腹水患者进行内科综合治疗的情况。结果30例患者经过内科综合治疗后取得了较好的临床效果,其治疗有效率达到了96.67%。结论对肝硬化腹水患者采用内科综合治疗措施进行治疗具有较好的临床效果,可以使患者的生存质量得到显著提高。     

影响儿童弱视治疗效果的因素分析

弱视是影响儿童视力的常见眼病,不但表现为视力差,且影响双眼单视和立体视觉,严重影响儿童的生活和学习[1],多年来,眼科医生已经积累了系统且正规的治疗儿童弱视的方法且治疗效果满意,但在临床治疗中仍有部分弱视儿童治疗效果欠佳,故将治疗效果良好和治疗效果差的儿童进行几方面的分析,以得到影响儿童弱视治疗效果的因素,在治疗中加以注意,以提高弱视治疗的疗效。     

正畸与修复联合治疗牙列缺损伴牙颌畸形患者的效果

目的:分析正畸与修复联合治疗牙列缺失伴牙颌畸形患者的治疗效果。方法:将40例牙列缺失伴牙颌畸形患者随机的分成两组,对照组采用修复治疗,观察组采用正畸与修复联合法治疗,比对两组的治疗效果。结果:观察组的治疗效果优良率远远高过了对照组的治疗效果,两组的治疗效果有明显的统计学差异。结论:对于牙列缺失伴牙颌畸形患者采取正畸与修复联合法治疗,其效果不错,可以恢复美观和生理功能等,在临床上值得推广使用。     

分析丙型病毒性肝炎的临床治疗效果

目的：研究分析临床治疗丙型病毒性肝炎的方法和效果。方法：根据我院接收的147例丙型病毒性肝炎患者来进行研究分析,患者临床中接受了巴韦林、单一干扰素、长效干扰素等治疗方式。结果：患者接受不同药物的治疗临床效果有差异性,治疗效果还受到了其他因素影响。结论：丙型病毒性肝炎患者接受标准联合治疗效果比较好,临床患者的病毒应答比较高。     

肝硬化临床治疗分析

目的:分析和探讨肝硬化患者的临床治疗效果。方法:选用了我院在2012年9月-2013年9月接收的56例肝硬化患者作为研究对象,将其随机分为了实验组和对照组,对照组患者给予了常规西药治疗,而实验组患者在西药治疗的基础上又给予了阿德福韦酯片抗病毒治疗,随后对两组患者的治疗效果进行对比。结果:实验组患者的治疗效果明显好于对照组,并且他们之间的差异具有统计学意义(P<0.05)。结论:肝硬化具有较高的发病率,对其进行系统性的治疗可以有效的提高患者的治疗效果。     

浅析心内科中生脉注射液的临床应用效果

目的:研究分析生脉注射液应用于心内科疾病的治疗效果。方法:根据我院接收的3例心内科患者使用生脉注射液进行治疗,对患者治疗效果和临床表现进行研究分析。结果:全部患者经过使用生脉注射液进行治疗后,其病情均有所改善,临床中表现比较优秀,比原用的治疗方式效果要好。结论:对心内科患者使用生脉注射液治疗,效果理想,患者的并发症情况得到了改善。     

急性三踝骨折的手术治疗

目的观察急性三踝骨折的手术治疗效果。方法对2009年1月～2012年3月收治的31例急性三踝骨折患者,均采用支撑钢板固定治疗,观察患者的治疗效果。结果 31例患者均得到了有效的治疗,随访6～12个月,患者无并发症发生,治疗效果优秀18例,良好12例,可1例。结论在急性三踝骨折治疗过程中采用支撑钢板内固定治疗的效果较好,值得应用。     

健康教育对~(131)I治疗甲亢的效果分析

目的　探讨健康教育对13 1I治疗甲亢的效果影响。方法　 77例住院的甲亢病人随机分为2组即实验组和对照组 ,对实验组进行了系统的健康教育 ,对照组只接受了一般性的入院宣教 ,然后对两组患者进行并发症及治疗效果方面的比较。结果　实验组患者的并发症的发生率明显低于对照组 ,治疗效果却明显优于对照组。结论　健康教育可提高13 1I治疗甲亢的治疗效果 ,减少并发症。     

缬沙坦联合氨氯地平治疗原发性高血压的疗效分析

目的:讨论并且分析应用缬沙坦联合氨氯地平治疗原发性高血压患者的临床效果。方法:回顾性分析医院曾经收治的180例原发性高血压患者的临床资料,随即将其分为观察组以及对照组患者各90例,其中观察组患者应用缬沙坦联合氨氯地平的治疗方案,对照组的患者则应用贝纳普利联合氨氯地平的治疗方案,观察并记录两组患者的临床治疗方法特点,比较分析两组患者的临床治疗效果。结果:全部180例原发性高血压患者经过了不同方法治疗之后,观察组的90例患者中,治疗效果达到了显效的患者有73例,治疗效果达到了有效的患者有15例,治疗无效的患者有2例,总有效率达到了97.8%;对照组的90例患者中,治疗效果达到了显效的患者有55例,治疗效果达到了有效的患者有26例,治疗无效的患者有9例,总有效率达到了90.0%,并且观察组治疗后的收缩压值和舒张压值以及心率值要显著低于对照组患者。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.