Who gains or who loses weight? Psychosocial factors among first-year university students

Self-reported weight changes over 7 months and their relation to psychosocial characteristics (self-esteem, depression, social support, perceived stress and transition perception) and eating attitudes and behaviors (restrained eating and Eating Disorder Inventory subscales [EDI]) were assessed in first-year male and female students at six Canadian universities (N=2753). Results showed small but significant weight increases over time in males and females (M=1.5 kg). Males who lost weight versus those who gained reported greater negative well-being and more negative feelings about university transition. Females who either lost or gained weight had higher initial restraint and EDI scores than did weight maintainers. At 3 months, total EDI and body dissatisfaction increased in female weight gainers compared to weight losers, plus greater drive for thinness compared to weight maintainers. Thus, males distressed at the transition from high school to university appear more likely to lose weight while well-adjusted males are more likely to gain weight. For females, however, weight gain is associated with more negative well-being and preoccupations with weight and eating.     

How well does the theory of planned behaviour predict alcohol consumption? A systematic review and meta-analysis

This study aimed to quantify correlations between theory of planned behaviour (TPB) variables and (i) intentions to consume alcohol and (ii) alcohol consumption. Systematic literature searches identified 40 eligible studies that were meta-analysed. Three moderator analyses were conducted: pattern of consumption, gender of participants and age of participants. Across studies, intentions had the strongest relationship with attitudes (r₊ = .62), followed by subjective norms (r₊ = .47) and perceived behavioural control (PBC; r₊ = .31). Self-efficacy (SE) had a stronger relationship with intentions (r₊ = .48) compared with perceived control (PC; r₊ = ?.10). Intention had the strongest relationship with alcohol consumption (r₊ = .54), followed by SE (r₊ = .41). In contrast, PBC and PC had negative relationships with alcohol consumption (r₊ = ?.05 and ?.13, respectively). All moderators affected TPB relationships. Patterns of consumption with clear definitions had stronger TPB relations, females reported stronger attitude–intention relations than males, and adults reported stronger attitude–intention and SE–intention relations than adolescents. Recommendations for future research include targeting attitudes and intentions in interventions to reduce alcohol consumption, using clear definitions of alcohol consumption in TPB items to improve prediction and assessing SE when investigating risk behaviours.     

Do changes in illness perceptions predict changes in psychological distress among oesophageal cancer survivors?

This study aimed to examine whether changes in the illness perceptions of oesophageal cancer survivors explain changes in their levels of psychological distress relative to demographic and biomedical variables and coping strategies. Oesophageal cancer survivors completed the Illness Perception Questionnaire - Revised, the Cancer Coping Questionnaire and the Hospital Anxiety and Depression Scale at two points in time, 12 months apart. Cluster analysis was used to identify groups of respondents who reported a similar profile of change in their illness perception scores over time. Findings suggested that enhancing control cognitions and encouraging a positive focus coping strategy may be important in improving psychological health.     

Does light alcohol consumption during pregnancy improve offspring's cognitive development?

We posit that: (i) light alcohol consumption during pregnancy does not improve the cognitive development of human offspring and (ii) observational study outcomes indicating apparent protective effects arise from residual confounding due to socioeconomic status. Our hypotheses counter emerging hypotheses apparent in the epidemiological literature that light alcohol consumption during pregnancy improves offspring’s cognitive development. Determining the plausibility of this proposition is important given its potential to influence women’s alcohol consumption behavior during pregnancy. However, given ethical concerns, it is unlikely that a randomized control trial will be conducted to test this hypothesis. The veracity of alcohol’s purported positive effect on cognitive development is therefore explored here by comparing research evidence on light alcohol consumption to the evidence for folate and DHA supplementation intake during pregnancy. An alternative approach for further testing this hypothesis in observational studies is also suggested.     

Do optimism and pessimism predict physical functioning?

Dispositional optimism has been shown to be related to self-report measures of health and well-being, yet little research has examined the relationship between optimism and more objective measures of functioning. The purpose of this study was to examine the relationship between optimism and pessimism and objective physical functioning. Four hundred eighty community-dwelling older adults with knee pain completed a measure of optimism and pessimism and were observed performing four daily activities (walking, lifting an object, climbing stairs, and getting into and out of a car). Results indicated that pessimism was significantly related to performance on all four tasks (p < .001), while optimism was related to performance only on the walking task (p < .05), after controlling for demographic and health variables.     

Do corticomotoneuronal cells predict target muscle EMG activity?

Data from two rhesus macaques were used to investigate the pattern of cortical cell activation during reach-to-grasp movements in relation to the corresponding activation pattern of the cell's facilitated target muscles. The presence of postspike facilitation (PSpF) in spike-triggered averages (SpTAs) of electromyographic (EMG) activity was used to identify cortical neurons with excitatory synaptic linkages with motoneurons. EMG activity from 22 to 24 muscles of the forelimb was recorded together with the activity of M1 cortical neurons. The extent of covariation was characterized by 1) identifying the task segment containing the cell and target muscle activity peaks, 2) quantifying the timing and overlap between corticomotoneuronal (CM) cell and EMG peaks, and 3) applying Pearson correlation analysis to plots of CM cell firing rate versus EMG activity of the cell's facilitated muscles. At least one firing rate peak, for nearly all (95%) CM cells tested, matched a corresponding peak in the EMG activity of the cell's target muscles. Although some individual CM cells had very strong correlations with target muscles, overall, substantial disparities were common. We also investigated correlations for ensembles of CM cells sharing the same target muscle. The ensemble population activity of even a small number of CM cells influencing the same target muscle produced a relatively good match (r >/= 0.8) to target muscle EMG activity. Our results provide evidence in support of the notion that corticomotoneuronal output from primary motor cortex encodes movement in a framework of muscle-based parameters, specifically muscle-activation patterns as reflected in EMG activity.     

Do somatic complaints predict subsequent symptoms of depression?

BACKGROUND: Evidence suggests substantial comorbidity between symptoms of somatization and depression in clinical as well as nonclinical populations. However, as most existing research has been retrospective or cross-sectional in design, very little is known about the specific nature of this relationship. In particular, it is unclear whether somatic complaints may heighten the risk for the subsequent development of depressive symptoms. METHODS: We report findings on the link between symptoms of somatization (assessed using the SCL-90-R) and depression 5 years later (assessed using the CES-D) in an initially healthy cohort of community adults, based on prospective data from the RENO Diet-Heart Study. RESULTS: Gender-stratified multiple regression analyses revealed that baseline CES-D scores were the best predictors of subsequent depressive symptoms for men and women. Baseline scores on the SCL-90-R somatization subscale significantly predicted subsequent self-reported symptoms of depressed mood 5 years later, but only in women. However, somatic complaints were a somewhat less powerful predictor than income and age. CONCLUSIONS: Our findings suggest that somatic complaints may represent one, but not necessarily the most important, risk factor for the subsequent development of depressive symptoms in women in nonclinical populations. The results also highlight the importance of including social variables in studies on women's depression as well as conducting additional research to further examine predictors of depressive symptoms in men.     

Does social anxiety predict rumination and co-rumination among adolescents?

Social anxiety in adolescence is manifested by anxiety about and avoidance of social interactions. The present study examined whether social anxiety predicts higher levels of both rumination and co-rumination over time. Rumination and co-rumination were studied as possible outcomes because the cognitive content of these processes often involves interpersonal concerns. A three-wave longitudinal study of 575 adolescents (aged 13-16 years old) was conducted over 6 months. Adolescent girls reported higher levels of social anxiety, rumination, and co-rumination than boys. Structural equation modelling analysis showed that social anxiety directly predicted higher levels of rumination and indirectly predicted higher levels of co-rumination over time. A gender difference was noted in that these relationships were more robust for girls than for boys.     

Does psychopathy predict institutional misconduct among adults? A meta-analytic investigation

Narrative reviews have raised several questions regarding the predictive validity of the Hare Psychopathy Checklist-Revised (PCL-R; R. D. Hare, 2003) and related scales in institutional settings. In this meta-analysis, the authors coded 273 effect sizes to investigate the association between the Hare scales and a hierarchy of increasingly specific forms of institutional misconduct. Effect sizes for Total, Factor 1, and Factor 2 scores were quite heterogeneous overall and weakest for physically violent misconduct (r-sub(w) = .17, .14, and .15, respectively). Moderator analyses suggested that physical violence effect sizes were smaller in U.S. prison samples (r-sub(w) = .11) than in non-U.S. prison samples (r-sub(w) = .23). Findings are discussed in terms of the utility of the Hare measures for decision-making in institutional and other contexts.     

Do implicit attitudes toward physical activity and sedentary behavior prospectively predict objective physical activity among persons with obesity?

This study conducted among adults with obesity examined the associations between implicit attitudes toward physical activity and sedentary behavior, and physical activity behavior measured 4 months later. At baseline, 76 participants (M _AGE = 56; M _BMI = 39.1) completed a questionnaire assessing intentions toward physical activity and sedentary behavior and two computerized Single-Category Implicit Association Tests assessing implicit attitudes toward these two behaviors. At follow-up, physical activity was measured with accelerometers. Multiple regression analysis showed that implicit attitudes toward physical activity were positively and significantly associated with physical activity when participants’ age, BMI, past physical activity and intentions were controlled for. Implicit attitudes toward sedentary behavior were not associated with physical activity. Adults with obesity who implicitly reported more favorable attitudes toward physical activity at baseline were more likely to present higher physical activity levels at follow-up. Implicit attitudes could be targeted in future research to enhance physical activity.     

Do haemostasis activation markers that predict cardiovascular disease exist?

Recognition of the central role of thrombosis in the pathogenesis of cardiovascular disease has prompted growing interest in the association of haemostatic variables with cardiovascular disease. In investigating the predictive value of haemostasis markers, a promising type of measurement is that of the activation products of coagulation and fibrinolysis: prothrombin fragment 1+2 (F1+2), fibrinopeptide A (FPA), soluble fibrin,thrombin-antithrombin (TAT), plasmin-antiplasmin(PAP) complexes and D-dimer. D-dimer was most extensively studied and there is substantial evidence that D-dimer is a strong, consistent predictor of cardiovascular events in the general population and inpatients with cardiovascular disease. Data on other markers are considerably less abundant and more controversial. The prognostic value of these markers remains to be fully defined in future epidemiological and clinical studies.     

Do preclinical testing strategies help predict human hepatotoxic potentials?

Overt hepatotoxicity due to drug administration is a real and present issue in drug development and regulatory circles. Preclinical drug development is intended to identify potential risks and target tissues prior to introduction of new molecular entities into the human population. The standard regimen is testing at various multiples of the intended human therapeutic dose in at least 2 species of animals, one rodent (rats or mice), one non-rodent (dogs,nonhuman primates, minipigs, and rabbits, as examples) for at least two weeks of repeated dosing. Experience has shown that this regimen "works"most of the time. However, preclinical models are not infallible and are not always predictive. Whether the lack of predictivity is due to individual human genetic sensitivities, immunologically mediated phenomena, disease mediation or idiosyncratic reactions, the animal models are limited in detecting these characteristics and other low incidence phenomena. While it is uncommon for drug developers to continue development with products that elicit overt hepatic toxicity early in the animal testing, some products have made it through the approval process and then shown significant adverse effects. Some of the drugs (acetaminophen, isoniazid, trovafloxacin, troglitazone, bromfenac, clarithromycin, telithromycin) that have shown this propensity will be discussed in detail from early preclinical development to marketing and, in some instances, to limitations to usage or removal from the U.S. marketplace.     

Do levels of dysfunctional attitudes predict recovery in major depression?

Thirty-seven patients who fulfilled DSM-lll-R criteria for Major Depressive Disorder were recruited for a double-blind controlled trial of desipramine and placebo for 6 weeks. Initial levels of dysfunctional attitudes in the placebo group, particularly those related to achievement, were found to predict changes in Hamilton Ratings for Depression between the initial Hamilton scores and those at week 6 (Hamilton change scores) with the initial level of depression controlled for. For subjects taking desipramine, levels of dysfunctional attitudes did not predict Hamilton change scores. The findings suggest that dysfunctional attitudes impair spontaneous recovery from depression and that the effects of antidepressant drug treatment may obscure this effect. Recovery from depression may include a complex mixture of biological and psychological pathways. © 1997 John Wiley & Sons, Ltd.     

Do infant behaviors following immunization predict attachment? An exploratory study

Objectives. The relationship between infant behaviors during routine immunization, pre- and post-needle, and infant attachment was explored. Methods. A total of 130 parent–infant dyads were recruited from a larger longitudinal study and videotaped during routine immunization at 12 months and the Strange Situation Procedure (SSP) at 14 months. Six infant behaviors were coded for 1-minute pre-needle and 3-minutes post-needle. Attachment was operationalized according to the secure/avoidant/resistant/disorganized categories. Results. As expected, none of the pre-needle behaviors predicted attachment. Proximity-seeking post-needle significantly discriminated attachment categorizations. Secure infants were more likely to seek proximity to caregivers post-needle in comparison with avoidant and disorganized infants. Proximity-seeking following immunization was positively correlated with proximity-seeking during the SSP and negatively correlated with avoidance and disorganization during the SSP. Conclusions. Infant proximity-seeking during immunization is associated with attachment security and parallels behaviors observed during the SSP. More research is needed to identify behavioral markers of disorganization.