宫腔镜辅助下分段诊刮术与单纯分段诊刮术诊断子宫内膜癌价值比较

目的:探讨宫腔镜辅助下分段诊刮术与单纯分段诊刮术在子宫内膜癌诊断中的应用价值,及是否增加腹腔冲洗液细胞学阳性率。方法:回顾性分析病理检查确诊为子宫内膜癌患者168例的临床资料,分为宫腔镜分段诊刮组75例和单纯分段诊刮组93例,比较两组术前病理诊断子宫内膜癌的准确性、判断宫颈受累的可靠性及腹腔冲洗液细胞学的阳性率,并同时分析病灶面积、组织学分级、肌层浸润深度及组织学类型等与腹腔冲洗液细胞学的关系。结果:宫腔镜组术前病理诊断的准确率为96%(72/75),单纯诊刮组为84.9%(79/93),两组比较差异有统计学意义(P<0.05)。宫腔镜组宫颈受累诊断的敏感度、准确率、阳性预测值、阴性预测值分别为75%、97.3%、100%和92%;单纯诊刮组分别为56%、82.8%、73.7%和85.1%,两组比较差异均有统计学意义(P<0.05)。宫腔镜组腹腔冲洗液阳性率为18.67%(14/75),单纯诊刮组为18.27%(17/93),两组比较差异无统计学意义(P>0.05)。腹腔冲洗液细胞学阳性与宫腔病灶面积有关(P<0.05),与组织学分级、肌层浸润深度及组织学类型无关(P>0.05)。结论:宫腔镜下分段诊刮可提高术前子宫内膜癌的病理诊断准确率,可准确评估子宫内膜癌患者宫颈受累情况,并且不增加腹腔冲洗液阳性率。腹腔冲洗液阳性率与宫腔病灶面积有关。     

宫腔镜检查对子宫内膜癌的诊断价值

探讨宫腔镜检查在子宫内膜癌诊断中的价值。方法 :经手术治疗的子宫内膜癌共 10 2例分为两组 :(1)宫腔镜检查组 (39例 ) ,在宫腔镜下行分段诊刮术 ;(2 )单纯分段诊刮组 (6 3例 )。比较两组术前后宫颈受累情况的诊断符合率及开腹手术时腹水细胞学检查的结果。结果 :两组患者的年龄、临床分期、病理分级及组织学类型差异无显著性 ,宫腔镜检查组诊断宫颈受累的准确率为 97.4% (38/ 39) ,明显高于单纯分段诊刮组 (76 .2 % ,48/ 6 3) ,其假阳性率 (0 / 35 )明显低于单纯分段诊刮组 (2 1.6 % ,11/ 5 5 ) (P值均 <0 .0 1) ,两组患者均无腹水 ,有 84.3 %(86 / 10 2 )在开腹手术时行腹腔洗液细胞学检查。宫腔镜检查组腹腔洗液细胞学阳性率为 8.8% (3/ 34) ,单纯分段诊刮组为 13.5 % (7/ 5 2 ) ,两组差异无显著性 (P >0 .0 5 )。结论 :宫腔镜检查可提高子宫内膜癌诊断的准确性 ,能较确切地了解宫颈是否受累 ,同时可能并不增加肿瘤细胞扩散的机会 ,对可疑宫内病变者应在宫腔镜检查下分段诊刮。     

宫腔镜检查对子宫内膜癌的诊断价值

目的：探讨宫腔镜检查对子宫内膜癌诊断中的价值。方法：经手术的子宫内膜癌共１０２例分为两组,（１）宫腔镜检查组（３９例）,在宫腔镜下特分段诊刮术;（２）单纯分段诊组（６３例）。比较两组术前后宫颈受累情况的诊断符合率及开腹手术的时腹水细胞学检查的结果。结果;两组患的年龄、临床分期、病理分级及组织学类型差异无显性,宫腔镜检查组诊断宫颈受累的准确率为９７．４％（３８／３９）,明显高于单纯分段诊刮组（７     

宫腔镜下诊刮在诊治子宫内膜息肉的临床应用

目的探讨宫腔镜下诊刮在诊治子宫内膜息肉中的临床应用价值。方法对187例因子宫异常出血行B超检查拟诊为子宫内膜息肉的患者,分别行宫腔镜及单纯诊刮,比较两种诊刮的诊断与诊刮标本病理诊断的符合率,对宫腔镜下诊刮者并行宫腔镜手术,术后口服妇康片并观察治疗效果。结果宫腔镜下诊断性刮宫病理结果符合率为92.5%,单纯诊断性刮宫病理结果符合率为76.4%,两者相比差异有显著性(P<0.05),术后月经恢复正常182例,有效率为97.3%。结论宫腔镜是诊治子宫内膜息肉的有效方法。     

分段诊刮术对子宫内膜癌宫颈受累的诊断意义

（１）目的 探讨分段诊刮术对子宫内膜癌宫颈受累的诊断意义。（２）方法 回顾分析我院１９８０～１９９５年间住院行子宫切除的子宫内膜癌病人６３例,对每个病人的术前分段诊刮和手术病理诊断结果进行比较。（３）结果 分段诊刮术对子宫内膜癌宫颈受累诊断的敏感性为８５．７％,特异性为７２．７％,其阴性预测值为９７．６％,而阳性预测值只有３１．８％。（４）结论 分段诊刮术对子宫内膜癌宫颈受累的阴性诊断结果较阳性诊     

宫腔镜辅助下分段诊断性刮宫术诊断子宫内膜癌的临床应用价值分析

目的:对宫腔镜辅助下分段诊断性刮宫(诊刮)术诊断子宫内膜癌的临床应用价值进行分析。方法:将选取的90例子宫内膜癌患者随机平分为观察组和对照组,观察组患者采用宫腔镜辅助下分段诊刮术进行诊断,对照组患者仅采用单纯的分段诊刮术进行诊断,观察两组手术前后的分期符合率和诊断的符合率。结果:观察组的诊断符合率为91.11%,明显较对照组(51.11%)高,差异具有显著性(P<0.05);观察组手术前后分期的诊断符合率为92.00%和95.00%,明显高于对照组(54.16%、33.33%),差异具有显著性(P<0.05)。结论:宫腔镜辅助下分段诊刮术对诊断子宫内膜癌有很高的准确率。     

比较宫腔镜与传统诊刮术在子宫异常出血中诊断的应用

目的比较宫腔镜与传统诊刮术在子宫异常出血中诊断的应用。方法选取该院2012年1月—2014年3月期间收治的54例子宫异常出血患者,所有患者均经诊断性刮宫术,并行宫腔镜治疗。比较两种诊断与术后病理诊断结果的符合率。结果 54例子宫异常出血患者经病理学诊断,32例为子宫内膜息肉,20例为子宫粘膜下肌瘤;与病理学诊断比较,宫腔镜检查符合率（90.6%）明显高于诊断性刮宫术（68.8%）（P〈0.05）;子宫粘膜下肌瘤宫腔镜检查符合率（85.0%）明显高于诊断性刮宫术（65.0%）,两组数据比较差异有统计学意义（P〈0.05）。结论宫腔镜下检查与治疗术在子宫内膜息肉和子宫粘膜下肌瘤引起的子宫异常出血的诊断中有明显的优势,值得临床推广。     

子宫内膜取样器与传统诊刮术对于子宫内膜评估及诊断价值的比较

 目的  探讨子宫内膜取样器应用于子宫内膜评估及诊断中的临床价值。方法  收集我院宫颈疾病诊疗中心2012年1至3月因各种指征需要评估内膜的患者115例,分别使用子宫内膜取样器和诊断性刮宫术采取子宫内膜组织,比较两者的病理诊断符合率,并观察子宫内膜取样器的取材满意度、术中疼痛及出血情况,手术并发症以及患者的依从性。结果  子宫内膜取样器取材满意度为97.4%,依从性高达100%,其和诊断性刮宫获取子宫内膜组织的病理诊断结果基本一致,为96.4%,其中对于生理性子宫内膜的诊断两者的一致率达100%。研究中未见并发症发生,无不良事件。结论  应用子宫内膜取样器是一种操作简单、基本无创、费用低、患者依从性好的内膜诊断方法。     

61例子宫内膜癌分段诊刮病理分析

目的 评价分段诊刮诊断子宫内膜癌的临床价值.方法 回顾分析2004年1月至2007年11月在宁夏医科大学院附属医院收治的61例子宫内膜癌患者,比较分析患者术前的诊刮和术后子宫病理诊断符合率及肿瘤细胞分级的符合率.结果 术前37例患者分段诊刮病理提示为"子宫内膜非典型增生",而24例术后子宫病理均诊断为"子宫内膜腺癌",术后病理升级.11例术后病检仍与前相符,术前组织学分级仅47例,G1、G2级例数极少,G3级6例术后4例符合.结论 分段诊刮对子宫内膜癌诊断是必不可少的.由于分段诊刮病理诊断中子宫内膜癌肿瘤细胞组织学级别被降低,临床上应重视分段诊刮的内膜癌病理报告.     

宫腔镜诊断子宫内膜癌的价值

<正>我院2005年1月至2010年1月,应用宫腔镜诊断子宫内膜癌52例,现将临床应用体会报道如下。临床资料1一般资料52例,年龄37~74岁,平均年龄53.6岁,     

Hysteroscopy and directed biopsy in the diagnosis of endometrial carcinoma

Background Diagnostic hysteroscopy and directed biopsy has been widely used to evaluate abnormal uterine bleeding. We aimed to explore the value of hysteroscopy and directed biopsy in the diagnosis of endometrial carcinoma.Methods Two hundred and eighty-seven patients with endometrial carcinoma who were treated in Beijing University People＇s Hospital, Beijing, China were distributed into 2 groups： Group A （90 patients） was examined using hysteroscopy and directed biopsy, and Group B （197 patients） was examined using fractional dilatation and curettage （D＆C）. The diagnostic veracity of the two methods, the rate of positive peritoneal cytology and the prognosis of the 2 groups were compared.Results In Group A, 97.8% （88/90） of patients were diagnosed pathologically before surgery; the rate was 88.8% （175/197） for Group B. The difference between the 2 groups was statistically significant （P ＜0.05）. The sensitivity,specificity, positive predictive value and negative predictive value for the two methods for detecting cervical involvement were 77.8%, 100%, 100% and 97.6% for Group Aand 65.3%, 92.6%, 74.4% and 90.0% for Group B, respectively. The positive peritoneal cytology rate was 5.6% （5/90） in Group A and 6.09% （12/197） in Group B. The difference was not statistically significant （P ＞0.05）. The 3-year and 5-year overall survival rates were 91.4% （33/36） and 82.4% （14/17） for Group A and 95.6% （87/91） and 86.7% （39/45） for Group B. There were no statistically significant differences between the two groups＇ survival rates （P ＞0.05）.Conclusion Compared with fractional D＆C, hysteroscopy and directed biopsy offered improved pathological diagnostic accuracy before surgery and discovered cervical involvement more precisely in endometrial carcinoma patients, but it did not increase the positive peritoneal cytology rate or affect the prognosis of these patients.     

宫腔镜在子宫内膜息肉治疗中的临床分析

目的研究子宫内膜息肉应用宫腔镜治疗的效果.方法 回顾性分析在60例我院行宫腔镜电切术治疗子宫内膜息肉的患者的临床资料.结果 所有手术均一次成功,平均手术时间为18min,平均出血量为30ml,无复发及并发症.结论 宫腔镜电切术治疗子宫内膜息肉,疗效显著,值得推广应用.     

经阴道超声及宫腔镜对绝经后妇女宫腔积液病因诊断价值

探讨经阴道超声、宫腔镜在绝经后妇女宫腔积液病因诊断中的价值。方法分析48例绝经后妇女宫腔积液的经阴道超声及宫腔镜检查结果,并与病理检查结果作对比分析。结果 48例宫腔积液超声确诊47例,误诊1例;宫腔镜检查宫腔良性疾病40例,发现恶性病变7例,病理诊断恶性病变4例,与病理诊断符合率57.14%。结论经阴道超声可作为筛查宫腔积液的首选方法,宫腔镜检查应配合诊断性刮宫或宫腔镜直视下活检方可对宫腔积液病因做出准确诊断。     

Accuracy of tumor grade by preoperative curettage and associated clinicopathologic factors in clinical stage I endometriod adenocarcinoma

Background Preoperative tumor grading becomes one of the most important predictors for lymphadenectomy at primary surgery for clinical stage I endometriod adenocarcinoma.However,there is an inconsistency of tumor grade between preoperative curettage and final hysterectomy specimens,and its associated factors are poorly understood.This study aimed to evaluate the accuracy of tumor grade by preoperative curettage so as to achieve a better stratified management for clinical stage I endometriod adenocarcinoma.Methods Clinical data of totally 687 patients with clinical stage I endometdod adenocarcinoma who underwent preoperative curettage and primary surgery were retrospectively collected.Compared with final hysterectomy specimens,the sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of tumor grade by preoperative curettage were calculated and their associations with clinicopathologic parameters,including age,status of menopause,position of uterus,location and size of lesion,histological grade,depth of myometrial invasion,cervical invasion,extrauterine spread,peritoneal cytology,metastasis to retroperitoneal lymph node,serum CA125 level,and hormone receptor status,were analyzed.Results In final hysterectomy specimens,139 of 259 grade 1 patients by curettage were upgraded to grade 1 or 2;31 of 296 grade 2 were upgraded to grade 3,with a significantly discrepant rate of 40.9% (281/687) and an upgraded rate of 24.7% (170/687).The specificity and negative predictive value for grade 3 were 90.7% and 89.9%,while the sensitivity and positive predictive value for grade 1 were 67.1% and 40.9%,respectively.Conclusions Preoperative tumor grade by curettage does not accurately predict final histological results,especially in those classified as grade 1.Complete surgical staging seems to be necessary for clinical stage I endometriod adenocarcinoma.     

Accuracy of tumor grade by preoperative curettage and associated clinicopathologic factors in clinical stage I

Background Preoperative tumor grading becomes one of the most important predictors for lymphadenectomy at primary surgery for clinical stage Ⅰ endometriod adenocarcinoma. However, there is an inconsistency of tumor grade between preoperative curettage and final hysterectomy specimens, and its associated factors are poorly understood. This study aimed to evaluate the accuracy of tumor grade by preoperative curettage so as to achieve a better stratified management for clinical stage Ⅰ endometriod adenocarcinoma. Methods Clinical data of totally 687 patients with clinical stage Ⅰ endometriod adenocarcinoma who underwent preoperative curettage and primary surgery were retrospectively collected. Compared with final hysterectomy specimens, the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of tumor grade by preoperative curettage were calculated and their associations with clinicopathologic parameters, including age, status of menopause, position of uterus, location and size of lesion, histological grade, depth of myometrial invasion, cervical invasion, extrauterine spread, peritoneal cytology, metastasis to retroperitoneal lymph node, serum CA125 level, and hormone receptor status, were analyzed. Results In final hysterectomy specimens, 139 of 259 grade 1 patients by curettage were upgraded to grade 1 or 2; 31 of 296 grade 2 were upgraded to grade 3, with a significantly discrepant rate of 40.9% （281/687） and an upgraded rate of 24.7% （170/687）. The specificity and negative predictive value for grade 3 were 90.7% and 89.9%, while the sensitivity and positive predictive value for grade 1 were 67.1% and 40.9%, respectively. Conclusions Preoperative tumor grade by curettage does not accurately predict final histological results, especially in those classified as grade 1. Complete surgical staging seems to be necessary for clinical stage Ⅰ endometriod adenocarcinoma.     

宫腔镜治疗子宫内膜息肉的临床分析

为探讨宫腔镜治疗子宫内膜息肉 (endometrialpolyp ,EP)的临床效果和手术的安全性 ,回顾性分析 2 0 0 1年1 1月至 2 0 0 2年 8月 ,在北京复兴医院宫腔镜中心门诊宫腔镜检查可疑EP并入院行子宫内膜息肉切除术 (transcervi calresectionofpolyp ,TCRP)的 1 0 8例患者的临床资料。结果 :全部手术均 1次完成 ,无手术并发症 ,病理报告EP符合者 98例 ,宫腔镜诊断与病理结果的符合率 90 .7%。术后随访 90例 ,EP所致月经增多者 84%症状改善 ,子宫不规则出血者 1 0 0 %症状改善 ,原发不孕者 2 6%术后妊娠成功。提示 :TCRP是治疗由于EP致月经紊乱 ,子宫不规则出血的安全有效的方法。TCRP术可发现非典型增生的EP及子宫内膜癌前病变 ,给予早期干预及治疗 ,积极预防子宫内膜癌。无症状的息肉患者 ,尤其是不孕症患者也应首选TCRP。     

经阴道三维超声和宫腔镜在绝经后子宫内膜良恶性病变诊断中的价值探讨

目的 通过对本院子宫内膜良恶性病变患者进行回顾性分析,探讨经阴道三维超声和宫腔镜在绝经后子宫内膜良恶性病变中的诊断价值。方法回顾性分析本院2010年10月~2014年6月疑似子宫内膜病变患者120例。以病理检查为确诊标准,分别采用经阴道三维超声和宫腔镜进行检查,比较两种检查方法的诊断结果。结果和宫腔镜对比,经阴道三维超声的诊断符合率、阴性检出率、特异性检出率明显低于宫腔镜,两种检查方法在这三个方面的数据比较差异具有统计学意义(P<0.05);然而,经阴道三维超声和宫腔镜在阳性检出率、敏感性比率两方面的数据比较差异不具有显著性(P>0.05)。结论经阴道超声检查是一种筛查子宫内膜病变较好的方法;阴道超声联合宫腔镜检查对诊断绝经后子宫内膜病变具有重要价值。     

子宫内膜癌B超分型与病理诊断对比研究

８３例子宫内膜癌术前经Ｂ超检查，Ｂ超诊断符合率８４．３％。总结Ｂ超声像图特点分为５种类型。Ｂ超分型评价子宫内膜癌深肌层浸润或超出子宫侵犯敏感性１００％，特异性８８．２％，准确性９２．８％；Ｂ超分型预测子宫内膜癌分期准确率９５．２％。