羊膜移植联合丝裂霉素C治疗翼状胬肉临床观察

目的观察羊膜移植手术联合丝裂霉素C治疗翼状胬肉的疗效。方法对38例44跟翼状胬肉按常规方法切除胬肉组织，巩膜裸露区采用保存的人羊膜移植。术后随访4～18个月。结果41眼术后角膜透明光滑，无新生血管，巩膜区结膜覆盖良好，充血消失。手术成功率93．2％，3跟复发(6.8％)。结论羊膜移植手术联合丝裂霉素C是治疗翼状胬肉理想的、复发率低的手术方法。     

干燥羊膜移植联合复合式小梁切除术治疗难治性青光眼临床观察

Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma.     

干燥羊膜移植联合复合式小梁切除术治疗难治性青光眼临床观察

Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma.     

干燥羊膜移植联合复合式小梁切除术治疗难治性青光眼临床观察

Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma.     

干燥羊膜移植联合复合式小梁切除术治疗难治性青光眼临床观察

Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma.     

干燥羊膜移植联合复合式小梁切除术治疗难治性青光眼临床观察

Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma.     

干燥羊膜移植联合复合式小梁切除术治疗难治性青光眼临床观察

Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma.     

干燥羊膜移植联合复合式小梁切除术治疗难治性青光眼临床观察

Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma.     

干燥羊膜移植联合复合式小梁切除术治疗难治性青光眼临床观察

Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma.     

干燥羊膜移植联合复合式小梁切除术治疗难治性青光眼临床观察

Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma.     

干燥羊膜移植联合复合式小梁切除术治疗难治性青光眼临床观察

目的探讨干燥羊膜移植联合小梁切除术治疗难治性青光眼的有效性和安全性。方法采用国产干燥羊膜移植联合复合式小梁切除术治疗难治陛青光眼32例（39眼）,术后随访6～24个月,检查记录术后视力、滤过泡、前房深度、眼压及术后并发症等情况。结果随访期间眼压由术前（41.3±5．1）mmHg降至术后（17．2±5．3）mmHg,比术前降低59．9％,P〈0．001。手术总成功率为93．4％,保持功能性滤过泡34眼（87．2％）,术后视力提高2行以上者为27眼（69．2％）,并发症主要包括浅前房（5眼）、低眼压（9眼）和前房积血（4眼）。结论羊膜移植联合复合式小梁切除术可减少滤过道疤痕的形成,提高手术的成功率,是治疗难治性青光眼安全有效的方法之一。     

羊膜移植联合丝裂霉素C治疗翼状胬肉56例临床观察

目的观察羊膜移植（AMT）联合丝裂霉素C治疗翼状胬肉的临床疗效。方法对56例翼状胬肉患者进行翼状胬肉切除,应用羊膜移植联合丝裂霉素C术中湿敷5min。结果术后随访12个月,所有患者除4只眼复发外,其余均治愈,治愈率为92.8%。结论羊膜移植联合丝裂霉素C是治疗翼状胬肉理想的、复发率低的手术方法。     

低浓度丝裂霉素联合羊膜移植治疗原发性青光眼的近期疗效分析

目的探讨羊膜移植联合低浓度丝裂霉素、小梁切除治疗原发性青光眼的效果。方法选择本院2011年6月～2012年12月收治的42例（60眼）原发性青光眼患者,将其随机分为研究组22例（30眼）和对照组20例（30眼）,研究组患者给予小梁切除、羊膜移植联合低浓度丝裂霉素治疗,对照组患者给予小梁切除治疗,观察两组患者治疗后眼压、视力的改变情况,并统计两组患者的并发症情况。结果研究组患者术后视力改善优良率明显高于对照组,组间差异有统计学意义（P〈0．05）;两组术后1、6个月眼压均较治疗前明显降低,差异有统计学意义（P〈0．05）;研究组术后1、6个月时的眼压明显低于对照组（P〈0．05）;研究组复发率及并发症发生率明显低于对照组,差异有统计学意义（P〈0．05）。结论低浓度丝裂霉素、羊膜移植、小梁切除治疗原发性青光眼可有效改善患者视力,眼压控制满意,复发率及并发生症发生率较低,值得推广。     

羊膜移植联合丝裂霉素C治疗睑球粘连32例临床观察

目的评价羊膜移植联合丝裂霉素C在治疗睑球粘连中的疗效。方法采用羊膜移植联合丝裂霉素C治疗睑球粘连32例(34眼),10天评价近期效果,随访观察6个月～1年,评价远期效果。结果32例中,29例粘连完全松解,眼球活动好,仅3例复发,占8.82%。结论采用羊膜移植联合丝裂霉素C是治疗睑球粘连的一种有价值的方法。     

羊膜移植联合小梁切除治疗难治性青光眼

目的探讨羊腰移植联合小梁切除治疗难治性青光眼的疗效。方法对24例25眼难治性青光眼进行羊膜移植联合小梁切除术后对眼压、滤泡、前房、视力进行3～7个月观察随访。结果术后3个月93．8％的眼压控制在8～20mmHg、6个月85．8％的眼压控制在8～20mmHg，5例5眼需局部加用降眼压药物。术后3个月23眼形成功能性滤泡，有效率为92％，6个月21眼形成功能性滤泡，有效率为91％，视力均有不同程度的改善，前房稳定。结论羊膜移植能有效防止滤过泡疤痕纤维化，是治疗难治性青光眼的简单、安全、有效方法。     

光凝虹膜联合小梁切除及应用丝裂霉素治疗新生血管性青光眼

目的评价氩绿激光行虹膜及前房角新生血管光凝联合小梁切除术,术中应用丝裂霉素C(MMC)治疗新生血管性青光眼的疗效。方法对28例(28眼)新生血管性青光眼先用氩激光对虹膜及前房角小梁网新生血管进行直接覆盖光凝,观察新生血管闭塞萎缩后,行小梁切除术联合术中应用0.2mg/ml MMC,术后观察降眼压效果、结膜滤过泡情况、眼前节炎症反应及其它手术并发症;随访时间为6～24个月。结果 28例术后第1周平均眼压(10.52±3.16)mm Hg较术前平均眼压(48.36±5.87)mm Hg明显降低(t=14.86,P=0.000),随访时眼压控制良好,平均(17.48±3.23)mm Hg,仅3例需用药物控制,术后眼压较治疗前有显著意义的降低(P<0.01)。23例结膜滤过泡弥散隆起,4例较为扁平,1例结膜切口II期愈合;6个月后功能性滤过泡存在有21例(21/28)。术中6例少量前房出血,术后2例继发少量前房出血。新生血管在术后早期全部消退,3月后出现3例(3/28);余无其它严重并发症发生。结论氩激光联合小梁切除术加术中应用丝裂霉素C是治疗新生血管性青光眼的一种有效方法。     

冷冻干燥羊膜移植联合板层角膜移植治疗蚕蚀性角膜溃疡

目的观察冷冻干燥羊膜移植联合板层角膜移植在蚕蚀性角膜溃疡中的临床应用及效果。方法对12例12眼蚕蚀性角膜溃疡进行板层角膜移植术及病灶临近球结膜、球筋膜切除后进行羊膜移植术。结果术后12例患者临床症状全部消失．随访一年以上，无一例复发。结论冷冻干燥羊膜移植联合板层角膜移植治疗蚕蚀性角膜溃疡，可显著降低术后病变复发率，有较好的临床效果。     

低浓度丝裂霉素C浸泡羊膜在翼状胬肉手术治疗中的应用价值

目的探讨低浓度丝裂霉素C浸泡羊膜在翼状胬肉手术治疗中的应用。方法随机将翼状胬肉需手术治疗患者146例,平均分为研究组（低浓度丝裂霉素C浸泡羊膜移植）和对照组（单纯羊膜移植）,观察组两组治疗效果及术后复发情况。结果研究组角膜愈合时间明显短于对照组,两组比较,差异有统计学意义（P〈0．05）,术后复发率明显低于对照组,两组比较,差异有统计学意义（P〈0．05）。术后1个月随访检查显示两组角膜曲率及散光度均较术前明显改善。前后比较差异有统计学意义（P〈0．05）,但术后组间比较差异无统计学意义（P〉0．05）。结论低浓度丝裂霉素C浸泡羊膜应用于翼状胬肉切除术,较传统的胬肉切除＋羊膜移植可加快角膜缘愈合,有效减少术后复发,是一种理想的手术方法．值得临床推广。     

3种方法治疗翼状胬肉的临床观察

目的比较翼状胬肉的常规切除术、羊膜移植术（Amniotic membrane transplantation，AMT）及AMT联合自体角膜缘移植术（Limbal autograft transplantation，LAT）对翼状胬肉的治疗效果：方法95例（97只眼），翼状胬患者随机分成3组，分别采用常规胬肉切除术、AMT及AMT联合LAT进行治疗．比较复发率。结果常规胬肉切除组复发半66．67％．AMT组复发率18．18％．AMT联合LAT组复发率0％。3组两两比较，差异有显著性：结论AMT联合LAT治疗翼状胬肉效果良好。     

丝裂霉素C联合Ahamed青光眼阀植入术治疗难治性青光眼的疗效观察

目的:探讨应用MMC联合Ahamed青光眼阀植入治疗难治性青光眼的临床疗效。方法:应用MMC联合Ahamed青光眼阀植入术治疗难治性青光眼17眼17例。结果:术前眼压45.6+8.49mmHg,术后降至20.2+6.84mmHg,视力有不同程度的提高。术后并发症4例早期术后浅前房,2例前房积血,1例引流管内口堵塞。结论:应用MMC联合Ahamed青光眼阀植入,可以有效地降低难治性青光眼的眼压,减少术后并发症的发生。