The Turkish version of the National Eye Institute Refractive Error Quality of Life Instrument: translation, validity and reliability

Purpose  To translate the original 42-item National Eye Institute Refractive Error Quality of Life Questionnaire (NEI-RQL-42) into Turkish and to investigate its validity and reliability. Methods  The linguistic translation followed the international guidelines of forward and backward translation. Ninety-five consecutive subjects (37 myopes, 18 hyperopes and 40 emmetropes) who had a visual acuity of 0.8 or better in the worse eye completed the NEI-RQL-42 and the Turkish version of the 25-item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25). Eighty patients completed the NEI-RQL-42 for a second time within 2 weeks. Psychometric evaluation of the Turkish NEI-RQL-42 involved the assessment of internal consistency, test–retest reliability, convergent and known-groups validity. Results  Internal consistency was generally high (Cronbach’s α = 0.83–0.95), with the exception of three subscales (glare, α = 0.65; suboptimal correction, α = 0.66; appearance, α = 0.62). Test–retest reliability, assessed by the intraclass correlation coefficient was good (ICC = 0.74–0.95) except for the subscale suboptimal correction (ICC = 0.61). Almost all subscales and the overall score showed significant inter-correlations. Low to moderate correlations were found between the subscales of the NEI-RQL-42 and the NEI-VFQ-25, which measure similar constructs. The NEI-RQL-42 showed good construct validity in terms of refractive error (myopia, hyperopia and emmetropia) and mode of refractive correction (spectacles, contact lens and no correction) discrimination. Conclusion  The Turkish version of the NEI-RQL-42 is a reliable and valid measure of vision-related quality of life in patients with refractive error. Preliminary results were presented as a poster at the Association for Research in Vision and Ophthalmology (ARVO). Annual Meeting in Fort Lauderdale, FL, 6–10 May 2007.     

The feasibility,reliability and validity of the McGill Quality of Life Questionnaire-Cardiff Short Form (MQOL-CSF) in palliative care population

In terminally-ill patients, effective measurement of health-related quality of life (HRQoL) needs to be done while imposing minimal burden. In an attempt to ensure that routine HRQoL assessment is simple but capable of eliciting adequate information, the McGill Quality of Life Questionnaire-Cardiff Short Form (MQOL-CSF: 8 items) was developed from its original version, the McGill Quality of Life Questionnaire (MQOL: 17 items). Psychometric properties of the MQOL-CSF were then tested in palliative care patients consisting of 55 out-patients, 48 hospice patients and 86 in-patients. The MQOL-CSF had little respondent burden (mean completion time=3.3 min) and was evaluated as ‘very clear’ or ‘clear’ (98.2%), comprehensive (74.5%) and acceptable (96.4%). The internal consistency reliability was moderate to high (Cronbach’s α=0.462–0.858) and test-retest reliability (Spearman’s r_s) ranged from 0.512–0.861. Correlation was moderate to strong (0.478–0.725) between items in the short form and their analogous domains in the MQOL. Most MQOL-CSF items showed strong associations with their own domain (r_s ≥ 0.40). Scores from MQOL-CSF significantly differentiated between patients with differing haemoglobin levels (p < 0.05). Construct validity was overall supported by principal component analysis. It is concluded that the MQOL-CSF is a feasible tool with favourable psychometric properties for routine HRQoL assessment in the palliative care population.     

Evaluation of the Quality of Life in Adult Cancer Survivors (QLACS) scale for long-term cancer survivors in a sample of breast cancer survivors

Background

The objective was to study whether a Kiswahili version of the OIDP (Oral Impacts on Daily Performance) inventory was valid and reliable for use in a population of older adults in urban and rural areas of Tanzania; and to assess the area specific prevalence, intensity and perceived causes of OIDP.

Method

A cross-sectional survey was conducted in Pwani region and in Dar es Salaam in 2004/2005. A two-stage stratified cluster sample design was utilized. Information became available for 511 urban and 520 rural subjects (mean age 62.9 years) who were interviewed and participated in a full mouth clinical examination in their own homes.

Results

The Kiswahili version of the weighted OIDP inventory preserved the overall concept of the original English version. Cronbach's alpha was 0.83 and 0.90 in urban and rural areas, respectively, and the OIDP inventory varied systematically in the expected direction with self-reported oral health measures. The respective prevalence of oral impacts was 51.2% and 62.1% in urban and rural areas. Problems with eating was the performance reported most frequently (42.5% in urban, 55.1% in rural) followed by cleaning teeth (18.2% in urban, 30.6% in rural). More than half of the urban and rural residents with impacts had very little, little and moderate impact intensity. The most frequently reported causes of impacts were toothache and loose teeth.

Conclusion

The Kiswahili OIDP inventory had acceptable psychometric properties among non-institutionalized adults 50 years and above in Tanzania. The impacts affecting their performances were relatively common but not very severe.     

学龄前儿童生命质量表的信度和效度分析

目的探讨学龄前儿童生命质量表(TAPQOL)的信度和效度。方法使用汉化的学龄前儿童生命质量表,将其应用在CA16感染和健康儿童,采用Cronbach'sα系数、Pearson相关系数、t检验和验证性因子分析方法,分析量表的信度和效度。结果总体Cronbach'sα系数为0.81,各维度Cronbach'sα系数范围为0.60~0.91,仅肺部功能(0.60)和皮肤功能(0.64)0.7;CA16感染和健康儿童各维度相关系数r值为-0.465~0.781,绝对数值大多数0.5,仅睡眠和食欲之间(0.536)、社会功能和正向情绪之间(0.526)、正向情绪和活力之间(0.781)相关系数0.5;根据碎石图及解释方差百分比提取了11个公因子,因子载荷值因子在0.54~0.86,均0.4;CA16感染儿童量表各维度得分范围为53.42~97.31,健康儿童为82.92~97.08;健康儿童在睡眠、食欲、肺部功能、胃部功能、问题行为、社会功能、焦虑、正向情绪和活力得分均高于CA16感染儿童,差异均有统计学意义(P值均0.05)。结论 TAPQOL量表具有良好的信度和效度,能够适用于国内学龄前儿童生命质量情况的测评。     

简体中文版皮肤病生活质量指标信度和效度初探

目的 评价简体中文版皮肤病生活质量指标(DLQI)量表的信度和效度。方法 对就诊皮肤科门诊的236例患者进行DLQI量表的测量,并计算其分值,用可靠性分析和因子分析进行评估。结果 DLQI量表克伦巴赫系数为0.87,折半信度为0.85,各维度之间相关性较高为0.4024～0.6569,因子分析发现单因素能够代表DLQI量表的大多数因子。结论 DLQI量表为简单有效的皮肤病生活质量测评工具,且具有较好的信度和效度。     

The Comprehensive Prevention Knowledge and Applications Survey Instrument: its validity and reliability

Because the instruments used to measure current practices among primary care physicians in a broad range of prevention activities are limited, we developed a study to test a tool that would evaluate current prevention knowledge and applications, including items regarding activities to prevent AIDS and other sexually transmitted diseases. The Comprehensive Prevention Knowledge and Applications Survey Instrument measures knowledge, counseling capabilities, and use of recommended applications in preventive medicine. We designed and tested a 74-item instrument. Four recognized experts in preventive medicine and public health determined its content validity. We then proceeded with reliability testing with a random sample of 315 family physicians and replicated it with an additional 432 physicians for stability reliability. Internal consistency reliability and stability reliability have both been demonstrated for this instrument.     

大学生生命质量评价简明量表研制与信效度分析

简化大学生生命质量评价专用量表(Questionnaire of Quality of Life of College Students,QOLCS-51),为快捷、动态地评价大学生生命质量提供参考.方法 通过定性研究和2轮调查对量表进行简化和验证,用SPSS 22.0和Lisrel 9.20分析2次调查问卷的信度和效度.结果 通过定性研究删减22个条目;第1轮调查后,删减6个条目;第2轮调查952名江苏、安徽、陕西大学生,显示大学生生命质量评价简明量表(QOLCS-23)的23个条目:难度系数0.44~0.68,均通过临界比率检验(P值均<0.01),题总相关系数均为0.33~0.60(P值均<0.01);78.26%的条目能敏感区分有无睡眠障碍的大学生.信度检验显示,各条目复测相关系数为0.71~0.86,简明量表Cronbach α为0.85;经探索性因子分析,形成6个因子,与理论框架基本吻合.效度检验显示,简明量表5个维度与原量表评价结果的相关系数均超过0.80.验证性因子分析显示,问卷效度好(x2/df=12.17,RMSEA=0.05,SRMR=0.07,GFI=0.84,AGFI=0.83,CFI-0.92,IFI=0.92,NFI=0.85,NNFI=0.91).结论 QOLCS-51删减28个条目后,形成23个条目的大学生生命质量评价简明量表,评价生理、心理、行为、环境、社会支持5个维度,信度和效度均高,更便于快捷、动态评价大学生生命质量.     

Validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in Korean breast cancer patients

ObjectivesThis study evaluated the validity and reliability of the Health-Related Quality of Life Instrument with 8 Items (HINT-8) in postoperative breast cancer patients in South Korea.MethodsThe study included 300 breast cancer patients visiting a tertiary hospital. We measured health-related quality of life (HRQoL) using the HINT-8, the 5-level EQ-5D version (EQ-5D-5L), and the Functional Assessment of Cancer Therapy-Breast (FACT-B). Discriminatory ability, known-group validity, and convergent validity were assessed. Reliability was evaluated with the Cohen kappa, weighted kappa, and intraclass correlation coefficient (ICC).ResultsThe EQ-5D-5L indexes (p<0.001) and EQ visual analogue scale (VAS) scores (p<0.001) were significantly higher in subjects with no problems in each item of the HINT-8 than in those with problems. The FACT-B total scores were also higher in subjects without problems on the HINT-8. Older age, lower education level, and comorbidities were associated with a lower HINT-8 index. The HINT-8 index was correlated with the EQ-5D-5L index and the EQ VAS, with correlation coefficients of 0.671 (p<0.001) and 0.577 (p<0.001), respectively. The correlation coefficients between the HINT-8 and the FACT-B ranged from 0.390 to 0.714. The ICC was 0.690 (95% confidence interval, 0.580–0.780).ConclusionThe HINT-8 showed appropriate validity for capturing HRQoL in postoperative breast cancer patients.     

Development and preliminary validation of the food intolerance Quality of Life Questionnaire (FIQLQ): Adult Form

Quality of Life Research - Approximately 20% of children and adults avoid certain foods because of perceived food intolerance. Valid and reliable health-related quality of life instruments are...     

Preliminary reliability and validity of Persian version of the Family Dermatology Life Quality Index (FDLQI)

Purpose

Family Dermatology Life Quality Index (FDLQI) is an instrument for assessing the quality of life of family members of dermatologic patients. The aim of this study was to describe the cultural adaptation of this questionnaire and to assess psychometric properties of the Persian version.

Methods

At first, the questionnaire was translated into Persian, and then back-translation was performed. The whole cycle was repeated until a consensus was reached about the optimal translation. In the next step, cognitive debriefing was performed, and after approval of the Persian version by FDLQI developers, it was distributed among 100 family members of dermatological patients in order to evaluate its validity and reliability.

Results

Mean age of participants was 37.1 years (±12.3). Mean score of FDLQI was 15.4 (±5.5) with maximum and minimum scores of 30 and 6, respectively. The quality of life of studied participants showed no significant difference based on age-group, sex, educational level and the family relationship. Cronbach’s alpha was calculated as 0.87. Exploratory factor analysis revealed a one-factor solution that accounted for 40.7 % of the variance. The unidimensional model was supported by confirmatory factor analysis.

Conclusions

The results of the present study showed that the Persian version of FDLQI has acceptable factorial validity and internal consistency reliability.     

The "Palliative Care Quality of Life Instrument (PQLI)" in terminal cancer patients

Background  

This paper describes the development of a new quality of life instrument in advanced cancer patients receiving palliative care.     

The reliability,validity and responsiveness of the Restless Legs Syndrome Quality of Life questionnaire (RLSQoL) in a trial population

Background  

The aim of this study was to determine the reliability, validity and responsiveness of the Restless Legs Syndrome Quality of Life questionnaire (RLSQoL) in a clinical trial setting.     

The validity of the MacNew Quality of Life in heart disease questionnaire

Background  

A previous review suggested that the MacNew Quality of Life Questionnaire was the most appropriate disease-specific measure of health-related quality of life among people with ischaemic heart disease. However, there is ambiguity about the allocation of items to the three factors underlying the MacNew and the factor structure has not been confirmed previously among the people in the UK.     

Assessing quality of life in young adult cancer survivors: development of the Survivorship-Related Quality of Life scale

Purpose

Scientific advances in treatments and outcomes for those diagnosed with cancer in late adolescence and early adulthood depend, in part, on the availability of adequate assessment tools to measure health-related quality of life (HRQOL) for survivors in this age group. Domains especially relevant to late adolescence and young adulthood (LAYA; e.g., education and career, committed romantic relationships, worldview formation) are typically overlooked in studies assessing the impact of cancer, usually more appropriate for middle-aged or older survivors. Current HRQOL measures also tend to assess issues that are salient during or shortly after treatment rather than reflecting life years after treatment.

Methods

To develop a new measure to better capture the experience of LAYA cancer survivors in longer-term survivorship (the LAYA Survivorship-Related Quality of Life measure, LAYA-SRQL), we completed an extensive measure development process. After a literature review and focus groups with LAYA cancer survivors, we generated items and ran confirmatory factor and reliability analyses using a sample of 292 LAYA cancer survivors. We then examined validity using existing measures of physical and mental health, quality of life, and impact of cancer.

Results

The final model consisted of two domains (satisfaction and impact), each consisting of ten factors: existential/spirituality, coping, relationship, dependence, vitality, health care, education/career, fertility, intimacy/sexuality, and cognition/memory. Confirmatory factor analysis and validity analyses indicated that the LAYA-SRQL is a psychometrically sound instrument with good validity.

Conclusion

The LAYA-SRQL fills an important need in survivorship research, providing a way to assess HRQOL in LAYAs in a developmentally informed way.     

The Audit of Diabetes-Dependent Quality of Life 19 (ADDQoL): feasibility, reliability and validity in a population-based sample of Australian adults

Purpose

This study aims to analyse the psychometric properties of the most recent 19 item version of the Audit of Diabetes-Dependent Quality of Life (ADDQoL) in a large, population-based sample of adults living in Australia.

Methods

A total of 3,951 people living with diabetes completed the ADDQoL as part of the Living With Diabetes Study. Data analysis investigated the feasibility of using the ADDQoL in a large, population-based survey; internal consistency; adherence to a single-factor structure; and convergent/discriminant validity.

Results

Data support the feasibility of using the ADDQoL in population-based survey research. Although a strict single-factor structure for the ADDQoL was not demonstrated, the results overall support an interpretation of essential unidimensionality. A validation matrix provides support for the convergent and divergent validity of the measure, as does the ADDQoL??s ability to discriminate between respondents based on insulin dependence and complications.

Conclusions

The ADDQoL has good psychometric properties and provides clinicians and researchers with a useful tool for comprehensively assessing quality of life in adults with diabetes.     

Feasibility, reliability and validity of the Thai version of the Pediatric Quality of Life Inventory 3.0 cerebral palsy module

Background

Quality of Life (QOL) and Health-related Quality of Life (HRQOL) are now considered as necessary outcome measures for children with cerebral palsy (CP). Various reliable and valid condition-specific HRQOL tools are available for these children. One of these is Pediatric Quality of Life Inventory (PedsQL) 3.0 CP module which has been widely used and was translated to many languages. As no Thai version is available, the authors have completed this translation.

Purpose

This study then aimed to investigate psychometric properties of the newly translated Thai PedsQL 3.0 CP module and to establish parent confidence in their ratings in the translated tool.

Methods

Translation of the PedsQL 3.0 CP module was performed based on linguistic translation guidelines. Then, the psychometric properties of the Thai version were established. PedsQL 3.0 CP module was completed by children with CP and their parents or caregivers twice with 2–4 weeks.

Results

Respondents were 97 parents or caregivers and 54 children. Minimal missing data were found. Acceptable internal consistency was supported except for Movement and Balance Scale (self-report). Intraclass correlation coefficients for parent proxy and self-report were good to excellent (0.684–0.950).

Conclusions

The feasibility, reliability and validity of the translated tool were supported.     

Reliability and validity of the French-Canadian Late Life Function and Disability Instrument in community-living wheelchair-users

Abstract

Objective: To examine the test–retest reliability, standard error of measurement, minimal detectable change, construct validity, and ceiling and floor effects in the French-Canadian Late Life Function and Disability Instrument (LLFDI-F). Method: The LLFDI-F is a measure of activity (i.e. physical functioning of upper and lower extremities), and participation (i.e. frequency of and limitations with). The measure was administered over the telephone to a sample of community-living wheelchair-users, who were 50 years of age and older, in this 10-day retest methodological study. The sample (n = 40) was mostly male (70%), had a mean age of 62.2 years, and mean experience with using a wheelchair of 20.2 years. Sixty-five percent used a manual wheelchair. Results: The test–retest intraclass correlation coefficients (ICC_2,1) for the participation component ranged from 0.68 to 0.90 and from 0.74 to 0.97 for the activity component. Minimal detectable changes ranged from 7.18 to 22.56 in the participation component and from 4.71 to 16.19 in the activity component. Mann–Whitney U-tests revealed significant differences between manual and power wheelchair-users in the personal and instrumental role domains, and all areas in the activity component. Conclusion: There is support for the test–retest reliability and construct validity of the LLFDI-F in community-living wheelchair-users, 50 years of age and older. However, because the majority of items in the lower-extremity domains of the activity component do not account for assistive device use, they are not recommended for use with individuals who have little or no use of their lower-extremities.     

Development and validation of the Chinese Quality of Life Instrument

Background  

This paper describes the development of the Chinese Quality of Life Instrument (ChQOL) which is a self-report health status instrument. Chinese Medicine relies very much on asking subjective feelings of patients in the process of diagnosis and monitoring of treatment. For thousands of years, Chinese Medicine practitioners have accumulated a good wealth of experiences in asking questions about health of their patients based on the concept of health in Chinese Medicine. These experiences were then transformed into questions for the ChQOL. It is believed that ChQOL can contribute to the existing Patient Report Outcome measures. This paper outlines the concept of health and disease in Traditional Chinese Medicine, the building of the conceptual framework of the ChQOL, the steps of drafting, selecting and validating the items, and the psychometric properties of the ChQOL.     

A Chinese version of the Sleep Apnea Quality of Life Index was evaluated for reliability, validity, and responsiveness

OBJECTIVE: Obstructive sleep apnea (OSA) is a common disorder in many ethnic populations. Patients with OSA have impaired health-related quality of life (HRQOL). No sleep apnea-specific HRQOL measure has been validated in Chinese patients. STUDY DESIGN AND SETTING: A cross-sectional sample of 106 Chinese OSA patients and a longitudinal sample of 51 patients in Hong Kong completed a Chinese (Cantonese) version of SAQLI for assessment of its acceptability, scaling assumptions, reliability, validity, and responsiveness. RESULTS: The instrument was understood and seen as relevant by 97% of subjects. Internal consistency, test-retest reliability, item-scale convergent validity and discriminatory validity, and construct validity were good to excellent. Construct validity was confirmed by significant correlations with SF-36 subscale scores. However, factor analysis showed that only items of daily functioning and symptom domains all loaded on the hypothesized scales. Longitudinal data showed that SAQLI was more responsive than SF-36 to changes after treatment. CONCLUSION: Hence, this version of SAQLI was an acceptable, psychometrically valid, and responsive HRQOL measure for evaluating impact of illness and treatment effectiveness in Chinese OSA patients.