阴道毛滴虫的研究进展

阴道毛滴虫是寄生在人体阴道及泌尿道的鞭毛虫 ,以性传播为主 ,主要引起滴虫性阴道炎 ,呈全球性分布 ,人群感染比较普遍 ,感染率各地不同 ,以女性 2 0～ 4 0岁年龄组感染率最高 ,平均感染率为 2 8% [1 ]。性罪错妇女、受 HIV感染的妇女和临床上可疑的 STD患者 ,其患病率远高于平均值 ,最高可达4 3.32 % [1～ 3]。很多男性不育症病人的配偶滴虫阳性率也明显高于正常妇女的感染率 [4 ]。1　致病阴道毛滴虫的致病力随虫株及宿主生理状态而变化。 (1)其粘附到人阴道上皮细胞上与之平行 ,根据其外形改变自己的形状 ,然后发挥细胞毒性作用。把…     

阴道毛滴虫病检测方法的研究进展

阴道毛滴虫 (Trichomonasvaginalis ,TV)是寄生在人体泌尿生殖道的一种常见病原体 ,可引起阴道毛滴虫病 (trichomoniasis)。自 1836年首次描述该虫的特点及所致疾病的症状以来[1] ,至今仍是威胁人类健康的主要的性传播疾病 (sexuallytransmitteddisease ,STD)之一[2 ] 。该病呈全球性分布 ,人群普遍易感。在女性 ,除主要引起滴虫性阴道炎外 ,还与许多围产期并发症相关。TV感染与子宫颈癌可能相关 ,据Zhang等[3] 调查 ,我国 4 %～ 5 %的子宫颈癌是由于TV感染所致。阴道毛滴虫感染也是引起不孕症的原因之一。在男性 ,可引起滴虫性疾患 (…     

女性尖锐湿疣患者阴道毛滴虫感染调查

阴道毛滴虫是人体泌尿生殖系感染的常见病原体 ,男女均可感染。可通过污染的公共浴池、游泳池、坐式马桶等间接传播 ,也可由性接触传播。在性活跃人群中发病率较高 ,有资料报道娼妓或淋病患者感染率可高达 30 %～ 70 % [1 ] 。但有关阴道毛滴虫在尖锐湿疣患者中的感染情况报道较少。为了解女性尖锐湿疣患者阴道毛滴虫感染情况 ,作者于 1999年 1月～ 2 0 0 0年 6月对 15 1例女性尖锐湿疣患者进行了阴道毛滴虫检查 ,现报道如下。1　临床资料15 1例女性患者全为我院性病门诊病人 ,年龄 16～ 45岁 ,平均 2 5 .6岁。病程 1周～ 15个月。健康对照…     

阴道毛滴虫遗传学特性研究

阴道毛滴虫 (Trichomonas vaginalis)是Donne于 1836年从脓性阴道分泌物和男性泌尿生殖道分泌物中首次发现 ,1916年被确认为妇女滴虫性阴道炎的病原体。 1957年发现了有效的治疗药物甲硝唑(metronidazole)。 196 2年临床首次报道阴道毛滴虫对甲硝唑具抗药性。最新资料表明 ,人体感染阴道毛滴虫可增加对其他性传播疾病病原体的易感性, 感染免疫缺损病毒 (HIV)的机率增加 2～4倍 ,促进HIV在人群中广泛流行 。阴道毛滴虫作为一种性传播疾病病原体越来越受到人们的重视。     

农村已婚妇女阴道毛滴虫感染现状及危险因素调查

目的了解农村已婚妇女阴道毛滴虫感染现状及影响因素，为实施干预措施提供依据。方法按经济水平分层整群随机抽样，以抽样村60岁以下已婚妇女为调查对象，进行阴道毛滴虫感染流行病学基线调查，同时采取阴道后穹窿阴道分泌物，悬滴法镜检阴道毛滴虫。结果在5781名被调查者中，共检出阴道毛滴虫感染者212例，总感染率3．67％。影响农村已婚妇女阴道毛滴虫感染的主要因素为：洁阴用具是否专用、每周清洗会阴次数、性病知识知晓水平。结论农村已婚妇女阴道毛滴虫感染与性病知识和洁阴习惯有关。     

妇科门诊病人阴道毛滴虫感染调查

阴道毛滴虫是引起人体泌尿生殖系统感染的常见病原体 ,严重危害妇女的身心健康 ,其传播方式主要为性接触 ,常伴有淋球菌的感染 ,被列为性传播疾病。阴道毛滴虫可吞噬淋球菌 ,是淋病单用青霉素治疗无效的原因之一。我们对本院妇科门诊病人中阴道毛滴虫的感染状况进行了连续 3年的调查。现将结果报告如下。材料和方法1　标本来源　 15 2 0份标本均来自 1996年 1月～ 1998年12月妇科门诊病人 ,其中 5 6份同时进行阴道毛滴虫和淋球菌的检测。2　淋球菌培养基　 T- M培养基 (OXOID公司产品英国 )。3　方法　由妇科门诊医生于病人阴道后穹隆处…     

4860名妇女阴道毛滴虫感染调查

阴道毛滴虫引起的阴道炎、尿道炎，是我国妇女常见病之一［１］，严重危害广大妇女身心健康，已被社会广泛重视，并作为妇女病普查的重要内容之一。现将我县妇女阴道毛滴虫感染情况报道如下。调查对象与方法按东南西北中方位，全县选５个点检查＞１６岁育龄妇女。调查参照赵慰先主编《人体寄生虫学》阴道毛滴虫检查方法［２］。结　果本次共调查＞１６岁育龄妇女４８６０人，其中阴道毛滴虫阳性５４５例，阳性率１１．２１％。检查已婚妇女４１２４人，阴道毛滴虫感染４８２例，感染率１１．６８％，未婚妇女感染率８．５６％（６３／７３６…     

湖南省辰溪县城镇妇女阴道毛滴虫感染情况调查

为了解我县城镇妇女阴道毛滴虫感染状况，我们于1991年至1993年对本县部分女职工及居民进行了妇科检查和阴道毛滴虫检查。检测对象1职工组为县城内企事业单位等已婚妇女，年龄ZO—50岁，共计1286人次。2居民组为县城内无正式工作的已婚妇女（包括个体户），年龄20－50岁，共计615人次。检验方法1由妇科医师取白带分泌物立即送检，寒冷天气保温送检。2用生理盐水涂片3张分别湿片镜检，如直见椭圆形或梨形有波动股或鞭毛的活动滋养体者即为阳性。结果本次检查结果见表1。职工组与居民组之间阴道毛滴虫感染率有显著差异（X2＝14．16，P＜0．0…     

阴道毛滴虫病与乳酸杆菌的相关性分析

滴虫性阴道炎是妇科常见病 ,是由阴道毛滴虫引起的阴道炎症。作者根据本院资料分析 ,发现阴道毛滴虫感染与年龄和乳酸杆菌有一定的关系。资料与方法对象全部资料来自本院 1996年 10月～ 1998年 7月妇科及泌尿生殖科门诊患者和体检妇女。体检组主要为教师、干部和工人 ,共 2 33例。年龄 2 3～ 6 6岁 ,平均 41.8岁。妇科及泌尿生殖科门诊患者 418例 ,年龄为 2～ 6 7岁 ,平均 32 .5岁。方法妇科采样 :按妇科常规操作 ,采阴道分泌物湿片及干片各 1张 ,立即送实验室检查。阴道分泌物检查 :1湿片用普通光镜检查上皮细胞、白细胞、念珠菌、阴道毛滴…     

阴道毛滴虫的治疗现状

阴道毛滴虫 (Trichmonas vaginalsi Donne,1837)是一种主要寄居于女性阴道和泌尿道的医学原虫。虫体形态多变 ,借助鞭毛、波动膜而活动。可引起女性的滴虫性阴道炎、泌尿道炎症。感染本虫的产妇 ,在阴道分娩的过程中 ,可将滴虫传染给婴儿。婴儿的感染主要表现于呼吸道和眼结膜的炎症。本虫也可感染男性泌尿和生殖系统 ,造成相应部位的炎症病变 [1 ] 。由于阴道毛滴虫在外界生存能力很强 ,在室温中的浴盆、浴衣、内裤、坐便器等表面能存活 0 .5～ 2 3h,因此极易传播[2 ] 。国外学者估计 ,全世界阴道毛滴虫感染者约有 1.8亿人。我国有统计报…     

青少年高血压的研究进展

随着人们生活和行为方式的改变,高血压发病明显呈年轻化趋势。在青少年时期识别高血压病高危人群有助于早期进行有效干预和治疗,降低未来高血压的发生率及其严重性。现试从青少年高血压的诊断、发病因素、特点、治疗策略等方面的研究进展作一综述。     

Morbidity in cardiovascular diseases in immigrants in Sweden

INTRODUCTION: Although immigration to Sweden has increased in the last few decades, the incidence rates of cardiovascular disease and coronary heart disease in immigrants are unknown. The aim of the present study is to estimate whether place of birth affects the incidence rates of cardiovascular disease and coronary heart disease. MATERIAL AND METHODS: The study was designed as a follow-up study on morbidity in cardiovascular disease and coronary heart disease between 1 January 1997 and 31 December 1998, including three and a half million persons with age range 35-64 years, of whom 550 000 were born abroad, from the database MigMed consisting of the whole Swedish population. Incidence rates and relative risks were estimated by indirect standardization and a proportional hazard model. RESULTS: The age-adjusted risk of coronary heart disease was higher in most foreign-born groups than in Swedes. For example, in nine of 12 male groups, the relative risks varied between 1.1 and 2.2, and in seven of 12 female groups, the relative risks varied between 1.4 and 2.5. When also adjusting for level of education and employment status, the risks were still high, but on a lower level. CONCLUSIONS: Foreign-born people possess an over-risk of cardiovascular or coronary heart disease(CVD/CHD) compared with Swedish-born persons, also when level of education and employment status are taken into account.     

C·肉毒杀鼠素(冻干剂)应用研究

目的为研究C·肉毒杀鼠索对杀灭达乌尔黄鼠(简称黄鼠)的大面积应用情况和对家畜、家禽的毒害作用,进行了C·肉毒杀鼠素的应用研究.方法大面积投毒采用ES-2药饵撒播机[1],间隔约80m进行条投.羊、鸡采用直接灌胃.结果大面积应用的灭鼠率为83.72%.对羊、鸡最高剂量分别为500万MLD、150万MLD,均未出现中毒现象.结论 C·肉毒杀鼠素是较为理想的草原大面积杀灭黄鼠的理想、首选药物.     

Pulmonary sporotrichosis in Oklahoma in susceptibilities in vitro

Six cases of pulmonary sporotichosis were observed in 2 institutions in Oklahoma City, Okla. Three of the patients were treated with iodides with or without surgery. Although one patient required a second course of iodides, the patients have remained well after at least 34 months of follow-up. Three patients treated with amphotericin B, single course as well as multiple courses, and other antifungal agents (hydroxystilbamidine and miconazole) have all relapsed. These cases and a reviewed of more than 40 cases of pulmonary sporotrichosis susceptibilities of Sporothrix schenckii that we observed in vitro suggest that amphotericin B is not an effective agent for the treatment of pulmonary sporotrichosis. It is our opinion that the treatment of choice for pulmonary sporotrichosis is a supersaturated solution of potassium iodide. If the patient is allergic to the medication or fails to respond, then a combination of amphotericin B plus flucytosine may be tried.     

Differences in outcome in primary angioplasty in women.

BACKGROUND: In acute myocardial infarction (AMI), primary percutaneous transluminal coronary angioplasty (PTCA) has proved to be the best therapeutic approach. Several factors have been associated with worse outcome in AMI in females. Are there differences in outcome in women undergoing PTCA for AMI? AIM: To evaluate gender influence on clinical outcome and in-hospital mortality in patients with AMI who undergo primary percutaneous interventions. METHODS: We studied 245 consecutive patients (72 women, 29.4 %), who underwent primary PTCA between January 2000 and December 2001. The following parameters were analyzed: risk factors for coronary artery disease including hypertension, diabetes, smoking, hypercholesterolemia and family history, previous AMI, PTCA or angina, pain-to-balloon time, extent of coronary disease and outcome. RESULTS: Female patients were older (67.9+/-11.6 vs. 59.6+/-13; p < 0.001) with a higher prevalence of hypertension (65.3 % vs. 47.4 %; p < 0.05) and angina (29.0 % vs. 16.0 %; p < 0.05) and lower prevalence of smoking (27.8 % vs. 54.3 %; p < 0.001). Pain-to-balloon time was longer in women (6.8+/-4.1 vs. 5.4+/-3.7 hours; p < 0.05). Extent of coronary disease was similar in both groups. Glycoprotein IIb/IIIa inhibitors were used in 84.7 % of women and 90.8 % of men. The frequency of hemorrhagic complications (5.6 % vs. 5.2 %) and arrhythmias (15.3 % vs. 10.4%) and in-hospital mortality (9.7 6.4 %) were higher in females, although without statistical significance (p = NS). Hospitalization time was similar in both groups. CONCLUSIONS: Despite the growing awareness of a gender bias in therapeutic approaches to AMI, there are still some differences in outcome, with a trend towards higher mortality rates in women. Older age and longer pain-to-balloon time could account for this.