Q开关Nd:YAG激光治疗色素性疾病220例

2003年1月￣2005年2月,笔者采用Q开关Nd:YAG激光对220例色素性疾病患者进行治疗,并长期随访观察,取得了显著疗效,现报道如下。1临床资料和方法1.1一般资料:本组病例220例,均为我科门诊患者,其中男67例,女153例,其中包括面部雀斑24例、老年斑32例、咖啡斑29例、外伤后色素沉着51     

Q开关Nd:YAG激光治疗外源性文身疗效观察

1998年1月～2008年1月,我们采用MedlireⅡ型Q开关Nd:YAG激光仪治疗外源性文身5 215例,取得了显著效果,现报道如下.     

Q开关Nd:YAG激光治疗外源性文身的临床观察

文身是指外源不容性的色素机械地引入真皮而使皮肤产生的一种永久性色素斑[1].外源性文身包括修饰性文身和外伤件文身两种,如文眉、文眼线、文唇等修饰性文身,以及车祸、爆炸等意外伤害引起的异常色素沉着[2].自1998年1月至2010年1月,笔者采用MedliteⅡ型Q开关Nd:YAG激光仪(美国康奥公司生产)对5856例外源性文身患者进行治疗,获得了较满意疗效.现报道如下.     

Q开关Nd：YAG激光治疗黄褐斑的疗效观察

目的：观察Q开关Nd：YAG激光治疗黄褐斑的疗效。方法：应用Medlite C6激光治疗仪（美国HOYA-ConBio公司生产）,波长1064nm,光斑大小6mm,能量2.5～3.5J/cm2,治疗120例黄褐斑患者,每周一次,共治疗10次,观察临床疗效及副作用。结果：120例患者经过治疗后,43例（35.8%）完全消退,68例（56.7%）明显消退,总有效率为92.5%。所有患者均述面部治疗区域皮肤质地较以前更光滑、细腻,无严重不良反应出现。结论：采用MedliteC6 1064nm大光斑、低能量治疗黄褐斑疗效显著、安全,副作用少。     

Q-开关Nd:YAG激光治疗外源性皮肤色素性病变124例

目的：观察Q-开关Nd：YAG激光治疗外源性皮肤色素性病变的临床效果。方法：用Q-开关Nd：YAG激光1064nm波长治疗黑色、灰色或蓝色皮肤色素性病变；532nm波长治疗红色色素性病变，共计124例。结果：此方法可明显去除外源性皮肤色素性病变，效果好、无瘢痕产生，但需多次治疗。结论：Q-开关Nd：YAG激光治疗外源性皮肤色素性病变安全有效。     

Q开关Nd:YAG激光治疗色素增加性皮肤病128例临床疗效分析

目的：观察Q开关Nd：YAG激光治疗色素增加性皮肤病临床疗效与美容效果以及治疗次数。方法：Q开关Nd：YAG激光(1064nm、532nm波长)治疗128例色素增多性皮肤病，观察并分析其疗效和美容效果。结果：Q开关Nd：YAG激光治疗色素增多性皮肤病的治疗有效。其中对文眉、雀斑、脂溢性角化、色素痣等总有效率为96％以上，治疗次数为1-4次。结论：Q开关Nd：YAG激光治疗色素增加性皮肤病特别是错误文眉治疗效果好。     

Q开关Nd∶YAG激光治疗颧部褐青色痣350例疗效观察

目的 观察Q开关Nd：YAG激光治疗颧部褐青色痣的疗效及不良反应。方法 用波长为倍频532nm，光斑3．0mm，脉宽5～10ns，能量密度1.6～1.8J／cm^2，脉冲频率5～10Hz治疗350例,术后3～6个月复诊，根据术前照片判定疗效，标准分Ⅳ级。结果 治疗次数最少1次，最多5次，共治愈133例(38．0％)，平均治愈次数2．1次，总有效率82．0％，疗效与治疗次数成正相关。结论 Q开关Nd：YAG激光波长为倍频532nm对颧部褐青色痣有很好疗效，一般治疗2～4次可基本痊愈。术后除部分病例色素沉着外，未见不良反应及并发症。     

国产Q开关Nd:YAG激光治疗色素增加性皮肤病

2004年5月-2005年3月，笔者应用国产Q开关Nd：YAG激光美容仪治疗色素增加性皮肤病患者862例，取得了满意疗效，现报道如下。     

Q开关Nd：YAG激光治疗太田痣1496例疗效分析

目的：回顾性分析Q开关Nd：YAG激光治疗仪治疗太田痣的疗效和安全性。方法：分析2006年3月～2011年3月笔者科室运用Q开关激光仪治疗1496例太田痣患者的临床疗效,根据治疗前后照片进行对比分析。结果：1496例太田痣经4～10次治疗,痊愈1311例,显效132例,有效53例,总有效率为100%。12例出现一过性色素沉着,所有患者均未出现严重不良反应。结论：Q开关Nd：YAG激光治疗太田痣安全、有效,治疗次数与疗效成正比相关,治疗次数越多,效果越好。     

Q开关Nd:YAG美肤激光治疗太田痣317例

目的:观察Q开关Nd:YAG激光系统治疗太田痣的疗效和安全性。方法:应用Q开关Nd:YAG激光仪对317例太田痣患者进行皮损区的多次照射治疗。治疗间隔时间2～3个月,根据皮损不同颜色、部位、年龄及治疗经验选择不同能量和光斑大小。结果:治疗次数与疗效成正比相关,治疗次数越多,效果越好。接受治疗≤5次时,儿童临床效果较成人好;远期疗效儿童组与成人组相同。结论:Q开关Nd:YAG激光治疗太田痣安全有效,预后好。     

Q-开关翠绿宝石激光治疗常见色素增加性皮肤病临床疗效观察

目的：探讨Q-开关翠绿宝石激光治疗常见色素增加性皮肤病的疗效及安全性。方法：应用AlexLazr Q-开关翠绿宝石激光不同剂量针对360例面部色素增加性皮肤病患者进行治疗,并随访3～6个月,观察治疗后效果及预后。结果：总有效率为98.6%,术后出现局部紫癜、疼痛、暂时性色素沉着、水疱等,无色素减退和瘢痕出现。结论：Q-开关翠绿宝石激光治疗常见色素增加性皮肤病安全、有效。     

Nd:YAG laser followed by radiation for treatment of malignant airway lesions

Patients with malignant obstructive airway lesions often present with total or segmental atelectasis of lung. In spite of prompt initiation of palliative external radiation alone, some patients were unable to complete the planned course of radiation therapy. Since May 1983, 17 patients with malignant obstructive endobronchial lesions have been treated by endoscopic Nd:YAG laser vaporization of the tumor. One to seven days later, fractionated external radiation therapy was initiated. Endoscopic use of the laser was repeated as needed during the course of treatment. Fifteen out of 17 patients successfully completed the planned course of therapy. The improved performance status was sustained in 13 of 15 patients for 2-13 months. A control group was selected from among patients with similarly located lesions who underwent external radiation treatment only prior to the availability of the Nd:YAG laser therapy. One patient developed radiation pneumonitis six weeks after completion of a second course of external radiation, another patient developed bronchopleural fistula after laser treatment which healed following closed chest tube drainage. The others had longer palliation of symptoms and improved quality of life. The results indicate that relief of airway obstruction by use of the Nd:YAG laser improved the patients' ability to tolerate subsequent external radiation treatment.     

Nd:YAG激光与强脉冲光非剥脱性嫩肤的动物实验

Objective To observe the histological change of different waves in treating SD rats of the long-pulse 1064nm Nd:YAG laser and the 560～1200 nm intense pulse light,in order to provide the theory bases of non-ablative rejuvenation.Methods Two waves were used on experimental mice.The dermic thickness and the expression of collagen typesⅠand Ⅲwere detected by HE stain and immunohistochemical methods. Semiquantitative analysis was used to determine the mean of absorbance.Results Thedermal thicknesses and the mean of absorbance of collagen typesⅠandⅢin two different waves were higher than those in common control groups(P＜0.05).The effect of Nd:YAG laser groups were higher than IPL groups(P＜0.05).The expression of collagen typeⅠwas higher than that of collagen type Ⅲ(P＜0.001).Conclusion After Nd:YAG laser or IPL irradiation,the dermal thickness and collagen typesⅠandⅢof SD rats are increased.The effects of Nd:YAG laser are better than those of 560～1 200 nm IPL.The expression of collagen type Ⅲ is obviously more than that of collagen typeⅠin the early,whereas the expression of collagen typeⅠis obviously more than that of collagen type Ⅲin the later.It proves that the mechanism of dermal remodeling of non-ablative skin rejuvenation is mainly correlation with raising range and time of collagen typeⅠ.     

长脉宽Nd:YAG激光治疗皮肤血管性病变的临床研究

目的 探讨波长为1064nm的长脉宽Nd:YAG激光治疗皮肤血管性疾病的疗效.方法 采用长脉宽Nd:YAG激光治疗鲜红斑痣、蜘蛛痣、毛细血管扩张等皮肤血管性病变,根据病变的不同选择不同的治疗参数,并对疗效进行分析.结果 本组患者215例获随访1年,长脉宽Nd:YAG激光治疗鲜红斑痣的痊愈率为15.4%,显效率为53.8%;治疗蜘蛛痣的痊愈率为76.8%,显效率为17.9%;治疗毛细血管扩张的痊愈率为18.6%,显效率为60.2%;治疗其他血管性病变的痊愈率为18.2%,显效率为54.5%.12例(5.6%)患者在术后发生了短暂性色素沉着;5例(2.3%)患者在术后发生了轻度瘢痕,无严重并发症发生.结论 长脉宽Nd:YAG 激光是一种治疗皮肤血管性病变安全、有效的方法.     

Q开关Nd:YAG激光不同波长治疗面部毛细血管扩张疗效比较

目的：观察Q开关Nd：YAG激光不同波长治疗面部毛细血管扩张的疗效及副反应。方法：128例病人按治疗波长随机分为532nm组75例，585nm组53例，治疗光斑2．0mm，能量密度2．2-6．8J／cm。，脉宽10ns；术后3个月根据术前照片判定疗效，标准分为Ⅳ级。结果：治疗次数1-4次，间隔时间3-5个月，两组共治愈71例(55，47％)，疗效与治疗次数成正相关。其中532nm组治愈36例(48．00％)，平均治愈次数2．64次；585nm组治愈35例(66．04％，)，平均治愈次数2．40次，两组痊愈率及副反应差异无显性。结论：Q开关Nd:YAG激光倍频532／nm和585nm两种波长对密度较低、直径较细的面部毛细血管扩张均有可靠疗效，术后除色素沉着发生较高外，其他不良反应较少。     

Endoscopic Nd:YAG laser surgery on malignant and benign lesions of the trachea and carina

A total of 47 patients with malignant and benign lesions in the trachea and carina were used to demonstrate the effectiveness of endoscopic Nd:YAG laser surgery. The histology consisted of 37 malignant and 10 benign lesions, and 23 of the patients had severe symptoms with laser surgery being performed as a lifesaving emergency. Endoscopic Nd:YAG laser treatment was able to dilate the tracheal calibers from, 2.6±0.9 mm to 6.1±1.4 mm in the emergency cases with a remarkable effect and brought relief from wheezing and dyspnea, with an objective improvement of more than 25 per cent in peak expiratory flow rate being demonstrated. Furthermore, the tracheal diameters were able to be dilated from about 7 mm to 10 mm in the non-emergency cases. A remarkable effect was achieved in patients with intraluminal or mixed types of tumors among both the emergency and non-emergency cases. The survival rates of the emergency patients in whom a remarkable effect was achieved were definitely better than those in whom only fair or poor effects were achieved and, in the non-emergency cases, similar results were demonstrated. In conclusion, the application of endoscopic Nd:YAG laser surgery to tracheal stenotic diseases has an instantaneous and definite effect on luminal dilatation and shows significance as a lifesaving procedure. Moreover, the resultant improvement in the patients' general condition could make it possible for them to undergo other combined therapy and prolong their life span. Endoscopic Nd:YAG laser surgery is thus considered to be a very effective and established procedure for the treatment of tracheal stenotic lesions.     

Nd:YAG laser clinical assisted in class II furcation treatment

The Nd:YAG laser efficacy associated with conventional treatment for bacterial reduction has been investigated throughout literature. The purpose of this study was to evaluate the bacterial reduction after Nd:YAG laser irradiation associated with scaling and root planning in class II furcation defects in patients with chronic periodontitis. Thirty-four furcation lesions were selected from 17 subjects. The control group received conventional treatment, and the experimental group received the same treatment followed by Nd:YAG laser irradiation (100 mJ/pulse; 15 Hz; 1.5 W, 60 s, 141.5 J/cm²). Both treatments resulted in improvements of most clinical parameters. A significant reduction of colony forming unit (CFU) of total bacteria number was observed in both groups. The highest reduction was noted in the experimental group immediately after the treatment. The number of dark pigmented bacteria and the percentage of patients with Porphyromonas gingivalis, Prevotella intermedia, and Actinobacillus actinomycetemcomitans reduced immediately after the treatment and returned to values close to the initial ones 6 weeks after the baseline for both groups. The Nd:YAG laser associated with conventional treatment promoted significant bacterial reduction in class II furcation immediately after irradiation, although this reduction was not observed 6 weeks after the baseline.