Dental health and cognitive impairment in an English national survey population

OBJECTIVES: To investigate the association between dental health and cognitive impairment and to examine the extent to which dental status accounts for the association between cognitive impairment and low body mass index (BMI) in a national survey sample. DESIGN: A secondary analysis of data from the Health Survey for England 2000. SETTING: A nationally representative cross-sectional population survey. PARTICIPANTS: Two thousand four hundred sixty-three adults aged 65 and older living in private households and 1,569 adults aged 65 and older living in care homes. MEASUREMENTS: Data collected by interview (self-reported or by proxy) included age, sex, level of education, disability, BMI, dental status, and cognitive function (Abbreviated Mental Test Score). RESULTS: Less than half of the community sample (40.4%) and 67.9% of the care home sample were edentulous; lack of teeth was significantly associated with cognitive impairment (odds ratio=3.59, 95% confidence interval=2.36-5.47). This association remained strong after adjustment for other covariates only in the community sample. Cognitive impairment was associated with lower BMI in both samples, but dental status did not explain this. CONCLUSION: Poor dentition is associated with cognitive impairment. Nutritional status in people with cognitive impairment is recognized to be at risk. Although dental health did not account for the association between cognitive impairment and low BMI in this sample, other possible nutritional consequences require further evaluation.     

Assessment of social cognition in frail older adults and its association with social functioning in the nursing home

PURPOSE: The aims of this study were to reliably assess a range of social-cognitive functioning in frail seniors and to examine the association between measures of social cognition and nurses' ratings of residents' social functioning in a nursing home. DESIGN AND METHODS: Forty nursing home residents with and without cognitive impairment completed 11 social cognition tasks on two occasions after assessment of their cognitive functioning with the Cambridge Cognitive Examination-Revised (CAMCOG), CAMCOG Executive Function, and two tests of working memory. Staff on the nursing units completed two measures of social behavior. RESULTS: Participants completed the social cognition protocol without difficulty. The measures demonstrated good internal (median alpha =.75) and test-retest reliability (median correlation =.70). Four of the social cognition measures were significantly associated with the measures of cognitive functioning; three additional measures showed significant positive associations with subsets of the cognitive tests. Regression analyses revealed that measures of social cognition were significantly and independently associated with nurses' ratings of residents' social functioning after age, gender, education, and the four measures of cognitive functioning were controlled for. One measure of social cognition that assessed interpersonal problem-solving accounted for 45% of the variance in nurses' ratings of participants' social functioning (F = 41.35; df = 1,17; p <.001). IMPLICATIONS: Measures of social cognition assess a domain of functioning that is not evaluated by traditional tests of cognitive status. These measures are informative about frail, older adults' ability to understand and respond to others and could be used to predict patterns of social functioning in nursing homes and other naturalistic settings.     

Can the family still cope? Social support and health as determinants of nursing home use in the older Mexican-origin population

OBJECTIVES: This article examines the impact of disability, cognitive status, and social support on nursing home use in a sample of older Mexican Americans. METHOD: We used four waves of the Hispanic Established Populations for Epidemiologic Studies of the Elderly (H-EPESE), a longitudinal study of 3,050 older Mexican Americans living in the Southwest initially contacted in 1993 to 1994. RESULTS: The findings reveal that advanced age, being a man, activities of daily living disability, and cognitive impairment are strong predictors of institutionalization and death. Living with family, arriving in the United States in late life, and access to social support independently decreased the probability of dying in a nursing home. DISCUSSION: Although it is clear that adequate social support can make it possible for an impaired older person to remain in the community serious impairment can eventually overwhelm even a supportive network and result in the institutionalization of an impaired older person.     

Factors associated with inconsistent diagnosis of dementia between physicians and neuropsychologists

OBJECTIVE: To explore reasons for discrepancy in the diagnosis of cognitive impairment between physicians and neuropsychologists. DESIGN: Retrospective analysis of national survey data. SETTING: Canadian Study of Health and Aging Phase 1, a national survey of community-dwelling and institutionalized older Canadians. PARTICIPANTS: 1879 subjects who completed all components of a clinical examination. MEASUREMENTS: Data available to both disciplines (demographic data, functional status, Modified Mini-Mental State (3MS), schedule H of the Cambridge Mental Disorders of the Elderly Examination (CAMDEX)), results of the physician's history and physical examination, and results of a psychometric test battery. Subjects were classified as No Cognitive Impairment, Cognitive Impairment Not Dementia (CIND), and Dementia, the latter according to the criteria of the Diagnostic and Statistical Manual, 3rd Ed., Revised. Preliminary diagnoses by physicians and neuropsychologists were compared. RESULTS: In univariate modeling, higher education increased consistency. Lower scores on the 3MS, depression reported in the CAMDEX, focal neurological signs, and all neuropsychological variables decreased agreement. In multivariate modeling, higher education and identification of long-term memory impairment by the neuropsychologist increased agreement; lower scores on the 3MS, depression reported on the CAMDEX, and identification of short-term memory impairment or constructional impairment led to disagreement. When the category of CIND was removed, kappa for agreement increased from 0.51 to 0.92. CONCLUSIONS: Physicians and neuropsychologists have different, complementary approaches to the diagnosis of dementia, and a consensus approach should be used. The category of CIND requires elucidation. Identification of dementia in subjects with depression or low education is difficult, and new strategies are required.     

Another look at aggregate changes in severe cognitive impairment: further investigation into the cumulative effects of three survey design issues

OBJECTIVES: This study explored whether previously reported declines in severe cognitive impairment were robust to cumulative effects of potentially confounding survey design issues. METHODS: Using the 1993 Asset and Health Dynamics of the Oldest Old study (n = 7,443) and 1998 Health and Retirement Survey (HRS; n = 7,624) the proportion of persons ages 70 and older with severe cognitive impairment was calculated under various assumptions about item nonresponse, differential loss to follow-up, and the size and composition of the nursing home population. Impairment was measured for self-respondents using a modified version of the Telephone Interview Cognitive Screen; for proxy respondents ratings of memory and judgment were used. Chi-square tests were adjusted to account for complex survey designs. RESULTS: Ignoring loss to follow-up, excluding nursing home residents, and assigning a low score to those refusing subscales yielded a statistically significant decline in severe cognitive impairment from 5.8% in 1993 to 3.8% in 1998, or an average annual decline of 6.9%. When cumulative effects of survey design issues were considered and design effects incorporated into statistical tests, statistically significant declines persisted, albeit at a reduced average annual rate, ranging from 2.5% to 6.9% per year. DISCUSSION: Previously reported improvements in severe cognitive impairment appear to be robust to a variety of specifications. Replication with future waves of the HRS and other data is warranted.     

Cross-domain variability of cognitive performance in very old nursing home residents and community dwellers: relationship to functional status

BACKGROUND: Recent evidence suggests that cross-domain variability in cognition may be related to subsequent cognitive decline beyond mean performance levels in cognitive tasks. OBJECTIVES: To examine age-related changes in cross-domain variability across cognitive task performance in very old nursing home residents in contrast to community-dwelling older adults. To explore the relationship between cross-domain variability in cognition and functional disability in very old age. METHODS: 204 very old (82.00+/-8.51 years) residents from the Jewish Home and Hospital, Bronx, N.Y., and 376 community-dwelling older adults of similar age (86.75+/-5.84 years) were tested on a cognitive battery. Cross-domain variability scores were computed across the cognitive tasks. Functional disability measures were derived from the CDR (Clinical Dementia Rating) Scale. RESULTS: Whereas oldest old community-dwelling adults showed a decrease in variability across domains with age, variability increased with age in nursing home residents, irrespective of the level of cognitive performance. Cross-domain variability was associated with functional disability beyond the effects of age, gender, education, dementia status, residential status, and level of cognitive performance. CONCLUSION: Findings suggest that cross-domain variability in cognition is related to functional decline with age. Cross-domain variability in cognition may be a prominent predictor for the development of functional decline in very old adults.     

Comparison of the physical fitness levels in nursing home residents and community-dwelling older adults

PurposeThis study aimed to compare the physical fitness levels of nursing home residents and community-dwelling older adults.Materials and methodsThe 118 older adults aged between 65–85 living in a nursing home or community participated in the study. The Senior Fitness Test assessed the physical fitness levels of older adults. The older adults performed the chair stand test, arm curl test, 2-min step test, chair sit and reach test, back-scratch test, 8-foot up, and go test.ResultsThe age, cognitive status, gender, body weight, height, smoking, and education status were similar between the groups (p > 0.05). Aerobic endurance, balance, and agility were higher in nursing home residents than in the community-dwelling older adults (p < 0.05). Strength, flexibility, and BMI did not differ between groups ​​(p > 0.05).ConclusionAerobic endurance, balance, and agility may vary depending on the living environment of older adults. The determination of differences in physical fitness between community-dwelling older adults and nursing home residents could provide objective information to develop a physical activity program for older adults.     

Gender differences in cognitive impairment and mobility disability in old age: A cross-sectional study in Ouagadougou,Burkina Faso

This study aims to examine differences in cognitive impairment and mobility disability between older men and women in Ouagadougou, Burkina Faso, and to assess the extent to which these differences could be attributable to gender inequalities in life course social and health conditions. Data were collected on 981 men and women aged 50 and older in a 2010 cross-sectional health survey conducted in the Ouagadougou Health and Demographic Surveillance System. Cognitive impairment was assessed using the Leganés cognitive test. Mobility disability was self-reported as having any difficulty walking 400 m without assistance. We used logistic regression to assess gender differences in cognitive impairment and mobility disability. Prevalence of cognitive impairment was 27.6% in women and 7.7% in men, and mobility disability was present in 51.7% of women and 26.5% of men. The women to men odds ratio (95% confidence interval) for cognitive impairment and mobility disability was 3.52 (1.98–6.28) and 3.79 (2.47–5.85), respectively, after adjusting for the observed life course social and health conditions. The female excess was only partially explained by gender inequalities in nutritional status, marital status and, to a lesser extent, education. Among men and women, age, childhood hunger, lack of education, absence of a partner and being underweight were independent risk factors for cognitive impairment, while age, childhood poor health, food insecurity and being overweight were risk factors for mobility disability. Enhancing nutritional status and education opportunities throughout life span could prevent cognitive impairment and mobility disability and partly reduce the female excess in these disabilities.     

Blood pressure-related cognitive decline: does age make a difference?

Systolic and diastolic blood pressures have been inversely related to cognitive performance in prospective and cross-sectional studies. However, in large, community-based samples, these findings have been limited to older adults. In this 20-year longitudinal study, we examined the relationship between baseline blood pressure and cognitive decline for 529 participants using 2 age groups (18 to 46 years and 47 to 83 years). Cognitive performance was measured over multiple examinations with the Wechsler Adult Intelligence Scale from which 4 scores were derived by factor analysis. A 2-stage growth curve method of analysis was used to model cognitive change. Results indicated that higher levels of baseline systolic blood pressure, diastolic blood pressure, mean arterial pressure, and blood pressure categories as defined by the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure were significantly associated with decline in Visualization/Fluid abilities in both younger and older age groups. Young adults are as susceptible to blood pressure-related longitudinal decline in cognitive performance as are older adults.     

Gender differences in cognitive impairment and mobility disability in old age: A cross-sectional study in Ouagadougou,Burkina Faso

This study aims to examine differences in cognitive impairment and mobility disability between older men and women in Ouagadougou, Burkina Faso, and to assess the extent to which these differences could be attributable to gender inequalities in life course social and health conditions. Data were collected on 981 men and women aged 50 and older in a 2010 cross-sectional health survey conducted in the Ouagadougou Health and Demographic Surveillance System. Cognitive impairment was assessed using the Leganés cognitive test. Mobility disability was self-reported as having any difficulty walking 400 m without assistance. We used logistic regression to assess gender differences in cognitive impairment and mobility disability. Prevalence of cognitive impairment was 27.6% in women and 7.7% in men, and mobility disability was present in 51.7% of women and 26.5% of men. The women to men odds ratio (95% confidence interval) for cognitive impairment and mobility disability was 3.52 (1.98–6.28) and 3.79 (2.47–5.85), respectively, after adjusting for the observed life course social and health conditions. The female excess was only partially explained by gender inequalities in nutritional status, marital status and, to a lesser extent, education. Among men and women, age, childhood hunger, lack of education, absence of a partner and being underweight were independent risk factors for cognitive impairment, while age, childhood poor health, food insecurity and being overweight were risk factors for mobility disability. Enhancing nutritional status and education opportunities throughout life span could prevent cognitive impairment and mobility disability and partly reduce the female excess in these disabilities.     

老年人认知衰弱的研究进展

在全球老年人口规模庞大、老龄化速度加快的社会背景下,认知衰弱（CF）作为影响老年人生活质量及生命健康的关键因素,逐渐受到国内外医疗护理领域的重视。我国认知衰弱（CF）的相关研究起步较晚,概念框架、影响因素、筛查评估、干预方式的研究结果尚未达成共识,与健康结局相关的研究基本处于空白,本文对以上认知衰弱（CF）相关要点进行综合概述,目的帮助国内医疗护理领域学者了解认知衰弱的研究现状及所处局限性,以便进一步明确研究方向,帮助优化当前社会老年人认知衰弱（CF）问题,为未来社会人口健康老龄化提供可靠数据支持。     

Intellectual and personality differences between community-living and institutionalized older adult females

The purpose of the present study was to investigate simultaneously differences between normal institutionalized older adults and community-living older adults with respect to intelligence/cognitive test performance and personality. Participants were 25 community-living females (M age = 72.9 yrs, SD = 6.34) and 25 institutionalized females (M age = 80.0 yrs, SD = 6.46). Intellectual/cognitive ability was assessed by the WAIS, Stanford-Binet Intelligence Scale (Form L-M), Ravens Coloured Progressive Matrices; personality was assessed by the Hand Test, a projective technique. Several multivariate analyses (discriminant analysis) were conducted. Results suggested that even when controlling for age and level of education, institutionalization appears to be associated with intellectual/cognitive as well as personality deficits. The findings were discussed in terms of the potential implications for the professional working with institutionalized older adults.     

Social networks and cognitive function in older adults receiving home- and community-based aged care

ObjectivesSocial engagement has been linked to preserved cognitive functioning in later life. Yet, little is known about the specific network factors that best predict cognitive function in older adults. This study aimed to (i) characterize the quality and quantity of interpersonal relationships and (ii) explore the relationship between social network types and cognitive function in older adults receiving home- and community-based aged care services.MethodsParticipants (n = 175) receiving aged care services participated in a structured interview regarding their cognitive function (Telephone Interview for Cognitive Status-Modified), social networks (Lubben Social Network Scale-12) and quality of life (European Quality of Life Scale). Socio-demographic and aged care service use factors were obtained from provider electronic management systems. Multiple regression analyses were conducted to examine the relationships between the size and composition of clients’ social networks, aged care service use and cognition.ResultsThe sample had a median age of 81 years (range 61-96) and most were women (65.8%). Over a third (37.6%) had cognitive impairment and reported moderately high social networks. Males had higher social networks, were receiving fewer hours but more types of services, and had significantly better cognitive performance. Age, network size and composition were not associated with cognitive performance.DiscussionMore extensive social networks were associated with maintenance of cognitive health for older adults in community aged care. Whether this is causal or a marker of better cognitive health requires a longitudinal approach, and ideally should be tested with interventions at community levels.     

Impact of hospital admission on functional and cognitive measures in older subjects

IntroductionHospital admission is frequently a major health transition for older adults, related with physical and mental disability that may persist after hospital discharge. We aimed to describe changes in physical and cognitive status in hospitalized older subjects, both during hospital admission and 3 months after hospital discharge, and to search for risk factors of impairment in physical and cognitive function.MethodsRandomized sample of all patients over 65 years admitted during a 5-month period, both for urgent or elective care. Basic and instrumental ADL and mental status were assessed on admission, at hospital discharge, and 3 months after discharge. Predictors of physical and mental disability were assessed.ResultsHundred and ninety-nine patients, mean age 75.9 years, were included. At hospital discharge, 16.5% of them had suffered a meaningful decrease in basic ADL, 24.6% in instrumental ADL, and 30.2% in cognitive tests. Three months later, 12.1% of those not lost or dead still reduced ability to perform basic ADL, 21.1% in instrumental ADL, and 35.2% had reduced cognitive scoring. In multivariate analysis, admission to surgical departments and discharge to a nursing home were related to loss of basic ADL; urgent admission and being widowed were related to loss of instrumental ADL; and older age, urgent admission, polypharmacy, and nursing home admission were related to reduced cognitive performance.ConclusionsPhysical and cognitive status change with hospitalization and after hospital discharge in older subjects. Some risk factors can be identified that predict these changes and allow for specific targeting of patients for preventive interventions.     

Asymptomatic bacteriuria and urinary tract infection in older adults

Asymptomatic bacteriuria (ASB) and urinary tract infection (UTI) are common in older community dwellers (ages 65 and older) and nursing home residents. The challenge involved in distinguishing ASB from UTI in this population results from other comorbid illnesses that may present with symptoms similar to UTI and from elderly adults who have cognitive impairment not being able to report their symptoms. This article reviews the most updated information on diagnosis, microbiology, management, and prevention of ASB and UTI as they pertain to older community dwellers and nursing home residents.     

Associations between dementia/mild cognitive impairment and cognitive performance and activity levels in youth

OBJECTIVES: To study the associations between dementia/mild cognitive impairment (MCI) and cognitive performance and activity levels in youth. DESIGN: Retrospective cohort study. SETTING: Research volunteers living throughout the United States. PARTICIPANTS: A total of 396 persons (mean age 75) who were graduates of the same high school in the mid-1940s. MEASUREMENTS: Adolescent intelligence quotient (IQ) scores were gathered from archived student records, and activity levels were determined from yearbooks. A two-stage telephone screening procedure (Modified Telephone Interview for Cognitive Status or Informant Questionnaire on Cognitive Decline in the Elderly followed by Dementia Questionnaire) was used to determine adult cognitive status. Data were analyzed using logistic regression to model the risk of cognitive impairment (dementia/MCI) versus no cognitive impairment as a function of IQ and activity level, adjusting for sex and education. RESULTS: High adolescent IQ and greater activity level were each independently associated with a lower risk for dementia/MCI (odds ratio (OR) for a 1-standard deviation increase in IQ=0.51, 95% confidence interval (CI)=0.32-0.79; OR for a unit increase in activity=0.32, 95% CI=0.12-0.84). No association was found between sex or education and adult cognitive status in this model. CONCLUSION: High IQ and greater activity levels in youth reduce the risk for cognitive impairments in aging. The mechanism(s) underlying these associations are unknown, but intelligence may be a marker for cognitive/neurological "reserve," and involvement in activities may contribute to "reserve." Early neuropathology and ascertainment bias are also possible explanations for the observed associations.     

Prevalence of physical and verbal aggressive behaviours and associated factors among older adults in long-term care facilities

Background

Verbal and physical aggressive behaviours are among the most disturbing and distressing behaviours displayed by older patients in long-term care facilities. Aggressive behaviour (AB) is often the reason for using physical or chemical restraints with nursing home residents and is a major concern for caregivers. AB is associated with increased health care costs due to staff turnover and absenteeism.

Methods

The goals of this secondary analysis of a cross-sectional study are to determine the prevalence of verbal and physical aggressive behaviours and to identify associated factors among older adults in long-term care facilities in the Quebec City area (n = 2 332).

Results

The same percentage of older adults displayed physical aggressive behaviour (21.2%) or verbal aggressive behaviour (21.5%), whereas 11.2% displayed both types of aggressive behaviour. Factors associated with aggressive behaviour (both verbal and physical) were male gender, neuroleptic drug use, mild and severe cognitive impairment, insomnia, psychological distress, and physical restraints. Factors associated with physical aggressive behaviour were older age, male gender, neuroleptic drug use, mild or severe cognitive impairment, insomnia and psychological distress. Finally, factors associated with verbal aggressive behaviour were benzodiazepine and neuroleptic drug use, functional dependency, mild or severe cognitive impairment and insomnia.

Conclusion

Cognitive impairment severity is the most significant predisposing factor for aggressive behaviour among older adults in long-term care facilities in the Quebec City area. Physical and chemical restraints were also significantly associated with AB. Based on these results, we suggest that caregivers should provide care to older adults with AB using approaches such as the progressively lowered stress threshold model and reactance theory which stress the importance of paying attention to the severity of cognitive impairment and avoiding the use of chemical or physical restraints.     

Physical restraint use and cognitive decline among nursing home residents.

OBJECTIVE: This study investigated the association between physical restraint use and decline in cognition. DESIGN: Cohort analytic study describing changes in resident characteristics. SETTING: Eight nursing homes, both urban and suburban, operated by a proprietary corporation in a large metropolitan area. PARTICIPANTS: 437 nursing home admissions, with 201 remaining at 1 year. MAIN OUTCOME MEASURES: Cognitive status was measured by geropsychiatrists, using the Folstein Mini-Mental State Exam, during a psychiatric evaluation of the resident. Daily restraint use was documented from nursing orders. Observations were made at 2 weeks, 10 weeks, and 1 year. RESULTS: Restraint use alone and in combination with neuroleptic use was associated with poor cognition. Other variables associated with poor cognitive scores were: ADL impairment, poor adaptive behavior, and longer time in the nursing home. The use of neuroleptics alone was not significant. Variables which were associated with good cognitive status were: being non-ambulatory but without dementia and having strong social support. CONCLUSIONS: These findings raise the possibility that restraint use may contribute to cognitive impairment, specifically among residents who have moderate to no cognitive impairment at admission; however, the findings do not exclude an alternative explanation that residents undergoing cognitive decline are more likely to be put in restraints. Further research is needed to understand whether factors which can be manipulated contribute to cognitive decline.     

Association of cognitive status with functional limitation and disability in older adults

BACKGROUND AND AIMS: Although cognitive status is known to be associated with physical function in older people, the role it plays in the disability process is not well established. This study aimed at determining whether cognitive ability predicts functional limitations, as well as disability, and whether it is associated with the rate of change in physical functions. METHODS: A community-based longitudinal study was conducted, involving 977 older persons aged 65 and older living in an urban community. Physical functions were assessed by tests scoring functional limitations (upper and lower body) and disability (activities of daily living). Cognitive function was evaluated using the Mini-Mental State Examination. Linear regression analyses with generalized estimating equations modeled the two physical function scores separately, as functions of cognitive status and time, in a one-year follow-up, controlling for sociodemographic and health-related characteristics. RESULTS: Cognitive status independently predicted functional limitations as well as disability in older people. In addition, the strength of the association of cognitive status with physical functions increased over time, as revealed by the significant interaction between cognitive ability and time. Cognitive status influenced the rate of change in disability scores, more among women and in those aged 75 or older. The relationship was unaffected by baseline physical functional status, but was significant only among those with no cognitive impairment at baseline. CONCLUSIONS: Cognitive status appears to be a useful indicator of the disablement process in older people. It may play an important role in the development of disability, implying that strategies for early intervention to prevent the progression of disability may need to take cognitive functions into account. The increasing strength of the relationship between cognitive and physical functions over time further attests to its value in monitoring functional change.