腹腔镜胰腺远端切除术26例

目的探讨腹腔镜胰腺远端切除术的安全性、可行性。方法2005年9月～2008年6月,对26例胰腺体尾部肿物行腹腔镜胰腺远端切除术。术前25例诊断为胰腺体尾部良性肿物,1例不除外恶性,肿物中位直径5cm（1.2～10cm）。结果所有手术均在全腹腔镜下完成。15例行保留脾脏的胰体尾切除（10例保留脾动静脉,5例未保留脾动静脉）,10例行胰体尾加脾切除,1例既往行胰体尾及脾切除者行胰体部切除。手术中位时间268.5min（129～400min）,中位出血量100ml（50～800ml）,术后中位住院时间9d（6～21d）。无胰漏或脾梗死发生,2例包裹性积液,均保守治疗治愈,1例引流管口感染。26例中位随访时间15.5月（1～35个月）,均无复发。结论胰腺体尾部良性肿物行腹腔镜胰腺远端切除术安全、可行。     

腹腔镜保留脾脏的远端胰腺切除术的外科技巧和临床应用

目的探讨腹腔镜保留脾脏的远端胰腺切除术的可行性及临床价值。方法对我院2005年12月至2013年12月间32例胰体尾部病变行腹腔镜远端胰腺切除术。术前肿物平均直径3.2 cm(1.5~7.5 cm)。结果所有手术均在腹腔镜下完成。7例行单纯保留脾脏远端胰腺切除术,未保留脾动静脉;25例行保留脾动静脉的保留脾脏远端胰腺切除术。平均手术时间为216 min(185~310 min),平均失血量280 m L(120~650 m L),术后平均住院时间10 d(7~23 d)。3例发生胰漏,保守治疗治愈。结论施行腹腔镜保留脾脏远端胰腺切除术是安全可行的,具有重要的临床应用价值。     

腹腔镜胰体尾切除30例报告

目的探讨腹腔镜胰体尾切除的安全性和可行性。方法 2013年1月~2016年6月对30例胰体尾占位性病变施行腹腔镜下胰体尾切除。术中定位肿物及胰腺切线,充分游离胰颈并应用Endo-GIA切断胰腺,根据肿物性质及肿物与脾血管关系决定是否保留脾脏。结果 4例因脾血管出血难以控制中转开腹。行腹腔镜保留脾脏胰体尾切除15例,其中保留脾血管的保脾胰体尾切除(Kimura法)10例,手术时间210~260 min,(232±14)min,术中出血量120~200 ml,(165±21)ml;不保留脾血管的保脾胰体尾切除(Warshaw法)5例,手术时间110~170 min,中位手术时间135 min,术中出血量50~130ml,中位出血量80 ml。胰体尾及脾切除11例,手术时间95~190 min,(137±31)min,术中出血量30~150 ml,(83±41)ml。术后住院时间7~22 d,(12.2±2.4)d。术后病理:黏液性囊腺瘤9例,实性假乳头状瘤7例,神经内分泌肿瘤6例,浆液性囊腺瘤3例,胰腺囊肿3例,导管内乳头状黏液瘤1例,异位脾脏1例。术后胰漏发生率36.7%(11/30),部分脾梗死1例。21例随访中位时间15个月(6~36个月),未见肿瘤复发。结论对于胰体尾良性、交界性或低度恶性肿瘤,选择腹腔镜下胰体尾切除安全可行,创伤小,恢复快。     

腹腔镜远端胰腺切除

目的 比较不同方式腹腔镜胰腺远端切除术的安全性、可行性.方法 2005年9月至2012年10月,57例胰腺体尾部肿物患者接受腹腔镜胰腺远端切除术.根据手术方式将患者分为远端胰腺及脾切除组、保留完整脾动静脉的保脾远端胰腺切除组、不保留脾动静脉的保脾远端胰腺切除组及中转开腹组.记录4组患者术中情况(包括手术时间、术中出血量、输血量等)、术后恢复情况(包括术后住院天数、并发症发生率等)以及病理资料,并进行对比分析.结果 57例患者中,5例中转开腹,52例完成腹腔镜手术(其中1例为手助).保脾手术22例(39％),非保脾手术30例(61％).4组患者手术时间、术中出血量,术后住院时间差异均无统计学意义(均P＞0.05).无手术死亡病例,术后B级胰漏2例,无C级胰漏.结论 不同术式的腹腔镜远端胰腺切除术均是安全的,应根据患者的具体情况选择不同术式.     

腹腔镜保留脾脏胰体尾切除术治疗胰腺囊性疾病6例报告

目的总结腹腔镜保留脾脏胰体尾切除术的临床经验与手术技巧。方法自2003年11月至2006年7月，我们对6例胰腺囊性疾病患者施行保留脾血管的腹腔镜保留脾脏胰体尾切除术。结果本组6例均在腹腔镜下完成，其中1例合并右肾上腺肿瘤切除，1例合并子宫肌瘤切除、左卵巢畸胎瘤切除，1例合并子宫肌瘤切除，1例合并胆囊切除。手术时间140～265min，出血350～600ml。术后住院时间4—9d，无胰漏发生。随访1—31个月，症状消失，未见复发。病理诊断：潴留性囊肿2例，浆液性囊腺瘤2例，黏液性囊腺瘤2例。结论对于胰体尾部良性病变，应首选保留脾血管的腹腔镜保留脾脏胰体尾切除术，施行保留脾血管的腹腔镜保留脾脏胰体尾切除术是安全可行的。     

腹腔镜胰体尾切除32例体会

目的总结腹腔镜胰体尾切除术(laparoscopic distal pancreatectomy,LDP)的手术体会,探讨其治疗胰体尾肿物的可行性和临床应用价值。 方法回顾性分析2016年1月至2019年12月就诊于沧州市人民医院肝胆外科诊断为胰体尾部占位性病变,行LDP的32例患者的临床资料。其中男12例、女20例,年龄13～75岁,平均(41.3±3.7)岁;术中根据肿物性质、肿物与脾血管解剖关系以及术中脾脏具体的损伤程度决定是否保留脾脏。 结果本研究纳入的32例胰体尾部占位性病变的患者中,仅有1例患者因肿瘤较晚侵犯了部分横结肠所以选择了中转开腹行胰腺尾部肿瘤＋部分横结肠切除术,其余31例患者均顺利在腹腔镜下完成胰体尾肿瘤切除术。其中行保留脾脏的腹腔镜胰体尾切除术(spleen preserving laparoscopic distal pancreatectomy,SPLDP)12例[其中应用Kimura法(脾血管保留) 8例、应用Warshaw法(脾血管切除)4例],腹腔镜联合脾脏胰体尾切除术20例。平均手术时间(252 ±75)min,平均术中出血量(162±51)ml;平均术后住院时间(11.6±3.2)d。32例胰体尾占位性病变患者的术后病理分别为：实性假乳头状瘤10例、浆液性囊腺瘤6例、黏液性囊腺瘤4例、神经内分泌肿瘤4例、腺癌3例、导管内乳头状黏液瘤3例、胰腺假性囊肿1例、胰尾部外伤性损伤1例。术后并发症：胰瘘10例,该10例患者通过保证创面通畅引流,同时给予抗感染、抑制胰液分泌等对症治疗后好转痊愈出院;乳糜漏1例,术后通畅引流,逐渐退管、闭管后好转痊愈出院;腹腔出血1例,通过给予生长抑素、止血药等保守治疗后痊愈出院;术后新发糖尿病5例,术后内分泌科随诊控制血糖。 结论LDP治疗胰体尾肿瘤是安全有效的,但是需要具有丰富腹腔镜手术经验的术者实施,术前综合精准评估制订良好的手术策略,术中熟练的手术操作技巧是提高LDP安全性、降低术后并发症的关键。     

保留脾脏的胰体尾部良性病变切除术8例报告

1995年 2月至 2 0 0 2年 12月 ,我院对胰体尾部良性病变施行切除脾动静脉保留脾脏的胰体尾切除术 8例。8例病人中 ,男 5例 ,女 3例。年龄 18～ 6 2岁 ,平均 4 0岁。术前CT检查均提示胰体尾良性病变 ,术中、术后病理证实其中胰腺囊腺瘤 2例 ,非功能性胰岛细胞瘤 1例 ,胰腺假性囊肿 3例 ,胰体尾外伤 2例。术前B超及CT检查脾脏正常 ,均行切除脾动静脉保留脾脏的胰体尾切除术。手术方法 :充分切开胃结肠韧带进入小网膜腔 ,置入S拉钩向上牵开胃壁 ,使胰体尾和脾门完全显露。控查肿瘤 ,并取少许组织送快速病理检查 ,如为良性肿瘤 ,则准备行保留…     

腹腔镜局部切除治疗胰腺良性和低度恶性肿瘤28例临床体会

目的 探讨胰腺良性和低度恶性肿瘤行腹腔镜下保留器官功能的局部切除术的安全性和有效性。方法 回顾性分析华中科技大学同济医学院附属协和医院胰腺外科2020年7月至2021年12月行腹腔镜下胰腺局部切除术28例病人的临床资料。28例病人中,胰头肿物16例(腹腔镜下保留十二指肠的胰头切除术13例,腹腔镜下胰腺肿物剜除术3例),胰腺颈体肿物7例(腹腔镜下胰腺中段切除术6例,腹腔镜下胰腺肿物剜除术1例),胰体尾肿物5例(腹腔镜下保留脾脏的胰体尾切除术3例,腹腔镜下胰腺肿物剜除术2例)。观察病人术中出血量、输血量以及手术时间、术后并发症等情况。结果 所有病人均在腹腔镜下顺利完成手术,无中转开腹病例。手术时间为60～450 min,术中出血量为20～550 mL,肿瘤直径为2～8 cm。术后并发症：B级胰瘘6例,C级胰瘘1例(胰头肿物剜除术1例),腹腔感染2例,胆瘘2例,胃瘫1例,腹腔出血2例(胰头肿物剜除术1例,胰颈体肿物行胰腺中段切除术1例)。术后随访8个月,未发现继发性胰腺内外分泌功能障碍。病人平均住院时间为20.9 d。术后病检：胰腺实性假乳头状瘤8例,胰腺神经内分泌肿瘤G1级5例、G2级2例...     

保留脾脏的胰体尾切除术研究进展

近年来,保留脾脏的胰体尾切除术倍受人们的关注.本文就胰体尾切除术中脾脏是保留还是切除、切除脾动静脉的保留脾脏胰体尾切除术是否安全、胰体尾部恶性肿瘤是否适宜保脾及腹腔镜保留脾脏的胰体尾切除术等方面的研究进展进行综述.     

保留脾血管的腹腔镜胰体尾切除术

目的:探讨保留脾脏血管腹腔镜胰体尾切除术的可行性与安全性。方法:回顾分析2011年3月至2014年7月为38例患者行保留脾血管腹腔镜胰体尾部肿瘤手术的临床资料。结果:手术时间116~295 min,平均(170.5±50.2)min;术中失血量15~565 ml,平均(112.3±33.6)ml;均未输血。病理检查结果示胰腺导管腺癌11例,浆液性囊腺瘤6例,黏液性囊腺瘤9例,黏液性囊腺瘤局部癌变2例,胰岛素瘤4例,实性假乳头状肿瘤6例。术后3例发生胰漏,经保守治疗好转。余者术后均恢复顺利,无并发症发生,术后平均住院(7.36±2.13)d。结论:腹腔镜保留脾脏血管胰体尾切除术是有效治疗远端胰腺肿瘤的新术式,具有微创优势,安全、可行。     

Changing management of organ-confined renal masses

BACKGROUND AND PURPOSE: Rapid evolution of laparoscopic and ablative techniques is changing the approach to renal masses. We evaluated our approach to managing renal masses in light of newly available technology. PATIENTS AND METHODS: The records for all patients who underwent treatment for a renal mass between January 2000 and July 2002 at UT Southwestern Medical Center were reviewed for patient demographics, operative details, and pathology results. There were 180 patients with 190 masses. Of the 190 masses, 97 were <4 cm, 47 were between 4 and 7 cm, and 46 were >7 cm. RESULTS: Most tumors >7 cm were managed with open radical nephrectomy (RN). For patients with masses between 4 and 7 cm, the majority were treated with laparoscopic RN, while 21% were treated by open partial nephrectomy (PN). Tumors <4 cm were treated with the widest variety of approaches. Open PN was the most commonly utilized, followed by laparoscopic RN and percutaneous ablation. The number of laparoscopic and percutaneous ablative procedures increased significantly with time, from none in the first year to 13% (7/55) and 29% (16/55) in the last year, respectively. Benign pathology was found in 20%, 17%, and none of lesions <4, 4 to 7, and >7 cm, respectively. CONCLUSIONS: The addition of laparoscopy and ablative technologies has increased the treatment options for patients with renal masses. We propose a treatment algorithm that incorporates ablative technologies and favors parenchyma-sparing approaches for small lesions.     

腹腔镜肾上腺巨大肿瘤切除术临床分析

目的:探讨腹腔镜肾上腺巨大肿瘤切除术的临床可行性及意义。方法:应用经腹腔途径为45例肾上腺肿瘤患者行腹腔镜肾上腺肿瘤切除术。术前均经B超、CT或MRI等相关影像学检查初步确诊。45例患者分为2组,32例肾上腺肿瘤直径5cm(A组),13例肿瘤直径5cm(B组)。观察2组患者手术时间、术中出血量、住院时间、中转开放率及围手术期并发症等情况。术后常规随访,定期行B超及胸片检查。结果:45例均顺利完成腹腔镜手术,平均手术时间(A组58.6min,B组86.7min)、术中平均出血(A组31.6ml,B组84.3ml)两组差异均有统计学意义(P0.01);中转开放手术A组3例(9%),B组1例(8%),两组差异无统计学意义(P0.05)。B组术中1例需输血;术后平均住院A组5.2d,B组5.7d,两组差异无统计学意义(P0.05)。术后患者均顺利康复。结论:与腹腔镜较小肾上腺肿瘤(5cm)切除术相比,腹腔镜巨大肾上腺肿瘤(5cm)切除术手术时间长,术中出血多,但住院时间及围手术期并发症无显著差异。只要术者具备娴熟的腹腔镜操作技巧及充分的临床经验,腹腔镜较大肾上腺肿瘤切除术切实可行。     

Laparoscopic adrenalectomy for isolated adrenal metastasis.

BACKGROUND: Laparoscopic adrenalectomy is accepted by many as the standard of care for the majority of adrenal masses less than 8 cm. The question exists whether laparoscopic removal of metastatic lesions to the adrenal is more difficult than laparoscopic removal of primary adrenal lesions. METHODS: We performed a retrospective analysis of all laparoscopic adrenalectomies performed at a single institution from 1998 to 2001, comparing laparoscopic adrenalectomies for primary lesions of the adrenal gland versus isolated metastatic lesions to the adrenal gland. RESULTS: Fourteen laparoscopic adrenalectomies were attempted, 10 for primary disease and 4 for metastatic disease. All 10 laparoscopic procedures were completed successfully for primary disease (average operative time=218 minutes, average tumor size=4 cm, median hospital stay=2 days). Only one of the 4 laparoscopic adrenalectomies for metastatic disease was completed successfully (average operative time=332 minutes, average tumor size=7.3 cm, median hospital stay=2 days). No major complications occurred in either group. CONCLUSIONS: We feel laparoscopic adrenalectomy is the preferred approach for primary adrenal masses less than 8 cm. Based on our experience and a review of the literature, isolated metastatic lesions to the adrenal gland appear less amenable to laparoscopic removal than do primary lesions of the same size.     

Organ intact retrieval via umbilical incision after simultaneous bilateral laparoscopic radical nephrectomy for renal masses

PURPOSE: We report on two cases of laparoscopic bilateral nephrectomy for renal-cell carcinoma (RCC) in patients with end-stage renal disease. PATIENTS AND METHODS: Bilateral renal masses were detected in two patients with acquired renal cystic disease. They underwent bilateral laparoscopic nephrectomy. The specimens were removed intact via an umbilical incision. RESULTS: The operative times were 8 hours and 6 hours and the estimated blood loss was 154 mL and 120 mL. Both patients resumed oral intake on postoperative day 1 and were discharged on postoperative day 6. No intraoperative and postoperative complications occurred. The pathology report revealed bilateral RCC. The original length of the umbilical incision was 4 cm which shrank to 3 cm by 2 months after the operation. CONCLUSIONS: Bilateral laparoscopic radical nephrectomy including intact organ retrieval for bilateral renal masses via a small umbilical incision is feasible.     

Is laparoscopic adrenalectomy safe and effective for adrenal masses larger than 7 cm?

Background Laparoscopic adrenalectomy (LA) has become the gold standard treatment for small (less than 6 cm) adrenal masses. However, the role of LA for large-volume (more than 6 cm) masses has not been well defined. Our aim was to evaluate, retrospectively, the outcome of LA for adrenal lesions larger than 7 cm. Patients and methods 18 consecutive laparoscopic adrenalectomies were performed from 1996 to 2005 on patients with adrenal lesions larger than 7 cm. Results The mean tumor size was 8.3 cm (range 7–13 cm), the mean operative time was 137 min, the mean blood loss was 182 mL (range 100–550 mL), the rate of intraoperative complications was 16%, and in three cases we switched from laparoscopic procedure to open surgery. Conclusions LA for adrenal masses larger than 7 cm is a safe and feasible technique, offering successful outcome in terms of intraoperative and postoperative morbidity, hospital stay and cosmesis for patients; it seems to replicate open surgical oncological principles demonstrating similar outcomes as survival rate and recurrence rate, when adrenal cortical carcinoma were treated. The main contraindication for this approach is the evidence, radiologically and intraoperatively, of local infiltration of periadrenal tissue.     

Extent of oncological resection in laparoscopic vs. open colorectal surgery: meta-analysis

BACKGROUND: Laparoscopy is not yet wide accepted in cancer colorectal surgery. This study investigated whether the extent of anatomical resection in laparoscopic colorectal surgery is equivalent to that in the open colorectal surgery. MATERIALS AND METHODS: We examined reports on the results of laparoscopic or open colorectal procedures published between 1990 and 1999 and selected 35 with data on lymph node count and distal margin clearance (total of 3935 patients). There were 16 comparative studies, 6 open series, and 13 laparoscopic series of patients. Several meta-analytic models were used to evaluate the difference between open and laparoscopic surgery, including multiple-outcome random-effects models that account for correlation between multiple-outcomes. RESULTS: More lymph nodes were extracted laparoscopically (0.3-2.14 lymph nodes more); however, only for the fixed-effects single-outcome model this difference was statistically significant. The average distal margin clearance was 4.6 cm with the laparoscopic approach and 5.3 with the open approach Accounting for random variation among the studies, the estimate of this difference obtained from meta-analysis was 0.64-1.19 cm, favoring the open approach; this difference was statistically significant. The estimated within-study correlation between lymph node count and distal margin clearance was 0.26 with the open and 0.19 with the laparoscopic procedure. The estimated within-study correlation between outcomes of laparoscopic and open procedures was 0.86 for the lymph node count and 0.96 for the distal margin clearance. CONCLUSIONS: This meta-analysis shows that laparoscopic approach is as adequate as the conventional approach. Estimates of difference between the two therapeutic options obtained from random-effects models were more precise than those from fixed-effects models.     

腹腔镜下胰体尾占位性病变切除16例体会

目的探讨胰体尾占位性病变行腹腔镜手术治疗的临床应用价值。方法回顾性分析自2014年开展腹腔镜胰腺手术以来成功完成的16例患者的临床资料。肿瘤直径1.0~12.6 cm,平均4.4 cm。行腹腔镜胰腺肿瘤摘除术4例,腹腔镜胰体尾脾切除术2例,腹腔镜胰体尾切除术10例。结果 16例患者均成功完成手术。手术时间90~330 min,平均210 min。术中平均出血量150ml。术后住院日4~28 d,平均11 d。术后病理回报黏液性囊腺瘤1例,浆液性囊腺瘤2例,胰岛素瘤5例,胰腺假性囊肿2例,实性假乳头状瘤2例,异位脾1例,自身免疫性胰腺炎1例,胰腺囊肿1例,胰腺癌1例。术后1例出现胰瘘,经通畅引流、抑酶对症治疗后痊愈;1例出现脾梗死,已随访1年,无临床症状及体征;1例出现结肠瘘,保守治疗痊愈。结论腹腔镜治疗胰体尾占位性病变是安全可行的。     

Delta吻合在完全腹腔镜远端胃大部切除术中的应用

目的回顾分析完全腹腔镜远端胃大部切除术Delta吻合的安全性和有效性。方法2011年4月-2014年5月,15例患者因胃癌行完全腹腔镜根治性远端胃大部切除术并采用Delta吻合完成胃十二指肠吻合。统计手术时间、吻合口瘘、吻合口出血、狭窄等并发症;淋巴结清扫数目,病灶和近、远端切缘间距离,随访生存情况。结果15例手术没有中转开腹病例,平均手术时间（274．9±55．5）min,Delta吻合平均耗时（32．6±4．9）min。没有吻合El瘘,1例患者在术后第10天、辅助化疗第2天上消化道出血,经保守治疗治愈。1例患者术后3个月吻合口狭窄,经保守治疗缓解。平均每例清扫（23．0±7．8）枚淋巴结,无阳性切缘,肿瘤距近、远侧切缘平均距离分别为（5．8±2．6）cm和（3．8±2．1）cm。1、3年累积生存率分别为92％、83％。结论Delta吻合操作简便、安全可靠,是胃窦部和胃体下部胃癌完全腹腔镜手术可供选择的消化道重建方法。     

国内腹腔镜结直肠癌切除术根治效果的Meta分析

目的 评价国内腹腔镜结直肠癌手术的肿瘤根治情况与远期预后.方法 检索2007年10月前国内临床中心以中英文公开发表的结直肠癌腹腔镜与开腹手术根治效果和远期疗效的非随机对照研究(non-randomized comparative studies,NRCs)文献,提取相关指标后综合分析.结果 14篇NRCs资料质量评分为18.92±1.27.腹腔镜与开腹治疗的患者基本特征均衡.结直肠癌腹腔镜手术的肠段切除长度较开腹手术短0.66 cm,远端切缘距肿瘤距离较开腹手术远0.26 cm,2年以上生存率是开腹手术的1.67倍.两种治疗方式的随访率、肿瘤直径大小、淋巴结清扫数目、肿瘤局部复发率和远处转移率差异无统计学意义.结论 NRCs资料的Meta分析认为国内腹腔镜与开腹手术治疗结直肠癌的肿瘤根治情况无差别,但2年以上生存率具有一定优势.