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Vasile Valeriu Lupu Ancuta Ignat Gabriela Paduraru Doina Mihaila Marin Burlea Anamaria Ciubara 《Medicine》2015,94(42)
Heterotopic gastric mucosa (HGM) of the esophagus is a congenital anomaly consisting of ectopic gastric mucosa. It may be connected with disorders of the upper gastrointestinal tract, exacerbated by Helicobacter pylori. The diagnosis of HGM is confirmed via endoscopy with biopsy. Histopathology provides the definitive diagnosis by demonstrating gastric mucosa adjacent to normal esophageal mucosa. HGM located in the distal esophagus needs differentiation from Barrett''s esophagus. Barrett''s esophagus is a well-known premalignant injury for adenocarcinoma of the esophagus. Malignant progression of HGM occurs in a stepwise pattern, following the metaplasia–dysplasia–adenocarcinoma sequence.We present a rare case of a teenage girl with HGM located in the distal esophagus, associated with chronic gastritis and biliary duodenogastric reflux. Endoscopy combined with biopsies is a mandatory method in clinical evaluation of metaplastic and nonmetaplastic changes within HGM of the esophagus. 相似文献
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Kenichi Kishimoto Kotaro Shibagaki Saya Nonomura Shohei Sumi Naoki Fukuda Yusuke Takahashi Satoshi Kotani Eiko Okimoto Naoki Oshima Kousaku Kawashima Norihisa Ishimura Shunji Ishihara 《Internal medicine (Tokyo, Japan)》2022,61(18):2735
Heterotopic gastric mucosa (HGM) of esophagus, primarily occurring in cervical esophagus, is usually asymptomatic. A healthy woman (mid-40s) with postprandial heartburn was diagnosed with middle esophageal HGM and esophageal ulcers by esophagogastroduodenoscopy. Using 8-channel pH monitoring, a sensor near the HGM area detected postprandial acid phase (pH 3-4), while areas adjacent to the proximal and distal sensors were neutral, suggesting acid secretion from the HGM. A biopsy showed fundic gland tissue expressing H+/K+-ATPase and pepsinogen-I. Oral vonoprazan improved the clinical symptoms and endoscopic findings. This is the first report using 8-channel pH monitoring to diagnose extremely rare middle esophageal HGM. 相似文献
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Hiromi Tanemura M.D. Satomi Uno M.D. Masao Suzuki M.D. Yohko Miyauchi M.D. Kuniyasu Shimokawa M.D. Shigetoyo Saji M.D. Hirofumi Ohashi M.D. Kazuki Sakata M.D. 《The American journal of gastroenterology》1987,82(7):685-688
An operated case of a heterotopic gastric mucosa, accompanied by an aberrant pancreas tissue, in the bulb of the duodenum was reported. A 40-yr-old man complained of epigastralgia and was diagnosed to have a protruding lesion in the duodenum by roentgenological and endoscopic examinations. Partial excision of the duodenal wall including the mass was performed. Cut surface of the specimen showed a yellowish-whitish mass in the submucosal through the subserosal layers, which was covered by a papillary elevated mucous membrane. Histologically the mass was an aberrant pancreas of the Heinrich I-type and the mucous membrane covering the mass was a heterotopic gastric mucosa, consisting of completely developed fundic glands. 相似文献
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Craig R. Blundell M.D. Carl S. Kanun M.D. David L. Earnest M.D. 《The American journal of gastroenterology》1982,77(2):111-114
Tumorous growths of heterotopic gastric mucosa have been infrequently found in the small intestine. Some have presented as intussusception and obstruction; others have been associated with mucosal ulceration, bleeding, and even more rarely with perforation. This ease report describes an elderly man who developed biliary obstruction secondary to a tumor mass of heterotopic gastric mucosa at the ampulla of Vater. 相似文献
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病例:患者女,62岁,主诉“上腹痛2年,牙龈出血2个月”于2010年4月19日收治入院。患者2午前于本院行肖镜检查并取活检,病理结果:(胃体)低分化腺癌(见图1),免疫组化检查:Ki-67(+)、CK(+)、CEA(+)。诊断“胃癌”明确,遂行胃癌根治术,术后未行后续治疗。患营诉间断上腹隐痛,服用药物不洋。2个月前自觉口腔右下颌磨牙区出现一包块,约黄豆大小,咀嚼时稍感小适,无疼痛。肿物生长较快,就诊时已有鹌鹑蛋大小,并时有出血,可自行停止。入院检查:全身一般情况好,左锁骨上方町扪及数个黄移大小的淋巴结,质硬,黏连,小可推动。心肺佥体未发现异常。 相似文献
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Iyad Subei M.D. Bashar Attar M.D. FACG Gregory Schmitt M.D. Hulya Levendoglu M.D. FACG 《The American journal of gastroenterology》1987,82(8):769-772
Gastric tuberculosis is a rare entity; it usually occurs secondary to another lesion(s), mainly in the lungs. Only a few cases of primary gastric tuberculosis have been reported in the literature. Most commonly, gastric tuberculosis lesion(s) is located in the lesser curvature of the antrum and prepylorus, so the clinical picture is similar to that of peptic ulcer, in addition to the constitutional symptoms seen in tuberculosis in general. We report a case of a young man presented with abdominal pain acute gastric outlet obstruction due to a large mass in the lesser curvature of the antrum and the pylorus. The histological examination revealed caseating granuloma with the presence of acid-fast bacilli. Partial gastrectomy with Bilroth II reconstruction was performed and the patient was put on antituberculosis medications. There was no evidence of the tuberculous lesion anywhere else. Patient's follow-up observation in the clinic was uneventful. 相似文献
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Osamu SAITOH Hiroya TAKIUCHI Yutaro EGASHIRA Sadaki SAKANE Ichiro SASAKI Junta TAKAMATSU Ichiro HIRATA Ken-ichi KATSU 《Digestive endoscopy》1998,10(3):223-226
Abstract: We report a patient with hyperthyroid Graves' disease associated with type A gastritis and a gastric carcinoid tumor. A 45-year-old female visited our hospital because of exophthalmos, and hyperthyroidism was found. TSH receptor antibody and anti-parietal cell antibody were positive in the patient's serum. An endoscopic examination revealed type A gastritis and a gastric carcinoid tumor. The diagnosis of type A gastritis was determined histologically. The gastric carcinoid tumor was solitary and small (less than 5 mm in diameter), and was removed by biopsy. The patient's hypergastrinemia continued after the thyroid function was normalized by treatment with methimazole. Endoscopic surveillance for metachronous gastric carcinoid tumors will therefore be required. The association of Graves' disease, type A gastritis and a gastric carcinoid tumor is discussed. 相似文献
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