Treatment of childhood anorexin with spleen deficiency by principle of invigorating spleen and benefiting qi

101 children of anorexia with Spleen deficiency were divided randomly into two groups, the invigorating Spleen(IS) group of 58 cases treated by modified Yi-Gong-San, and the replenishing zinc(RZ) group of 43 cases treated by 0.2% zinc sulphate syrup. One course of treatment was 3 months. Results: the clinical effects of IS group were notable in promoting appetite, increasing body weight and height, eliminating polyhidrosis, preventing common cold and tracheitis etc. The total effective rate was 96.6% in IS group which was significantly better than 72.1% in the RZ group (P less than 0.01). The effect of examination showed that the levels of hair zinc after treatment were markedly increased in both groups (P less than 0.01). The average increased value of hair zinc was 62.2 +/- 9.1 (ppm) in IS group which was higher than 42.1 +/- 7.2 (ppm) in RZ group (P less than 0.05). Moreover excretion rate and Hb after treatment in the IS group were markedly higher those in the RZ group (P less than 0.01). Chemical analysis showed that the concentration of zinc in modified Yi-Gong-San was very slight (0.73 mg/pack). It indicated that arising hair zinc in IS group was not simply supply of zinc but also the treatment in appetite, digestion and absorption, with which the body was supplied enough zinc naturally by food taken.     

哮喘病人头发和血清锌、铜的测定与分析

７３例哮喘病人与健康人相比，发锌、铜含量下降（Ｐ＜０．０１），血清锌含量下降（Ｐ＜０．０１），血清铜含量增高（Ｐ＜０．０１）。     

壮龄剂对人胚肺二倍体细胞的抗老化实验研究

本研究用体外培养人胚肺二倍体成纤维细胞作为壮龄剂抗老化研究的细胞模型,从35代开始,于培养液中加入壮龄剂者为实验组,不加药为对照组。现察了壮龄剂对二倍体细胞的形态结构、生长速度和增殖的影响。结果是实验组细胞的传代寿命为68代,对照组为51代,实验组比对照组多传17代,能延长细胞寿命33.3％代。实验组细胞的生长状态,速度和酸性磷酸酶活性变化均比同代对照组细胞好。这些结果证明了壮龄剂有促进细胞生长增殖和抗老化作用。     

维吾尔族发旋的调查

本文报告了新疆维吾尔族425名大学生的发旋调查情况。发现维吾尔族的单旋顺旋率明显高于汉族(P<0.05),极显著高于壮族和瑶族(P<0.01),而反旋率低于汉族(P<0.05),明显低于壮族及瑶族(P<0.01)。双旋顺反旋率高于壮族(P<0.05),低于瑶族(P<0.01),顺顺旋率均高于汉族、壮族及瑶族(P<0.01)。提示了发旋这一性状有着明显的民族差异。     

厌食儿发锌、铁、铜测定分析(附110例病例报告)

本文对110例厌食儿及健康儿行发锌、铁、铜含量测定。结果显示厌食儿发锌含量明显低于健康儿，P＜0．01；而发铜、铁含量基本正常，两组间差异无显著性，故提示厌食是缺锌的最早症状之一。同时对两组间Cu／Zn比值进行比较，结果表明厌食组明显高于健康组（P＜0．01）说明体内微量元素变化以锌明显，Cu、Zn含量呈负相关。     

印刷业重金属污染对工人微量元素水平的影响

目的研究印刷业中重金属污染因素对人体健康的危害。方法采集印刷包装作业工人和非作业人群的头发、血清样品,用电感耦合等离子体原子发射光谱仪(ICPS-7000)测定锰(Mn)、铅(Pb)、铬(Cr)、铜(Cu)和锌(Zn)的质量浓度。结果印刷车间工人血清中Cr、Mn、Cu的质量浓度明显高于非作业人群(P<0.05),血Zn质量浓度明显降低(P<0.05);头发中Cr、Mn的含量明显高于非作业人群(P<0.05),发Cu和Zn含量明显降低(P<0.05);2组人群血Pb和发Pb含量的差异无统计学意义(P>0.05)。结论印刷业重金属污染可能对从业工人体内微量元素水平产生影响。     

微量元素锌与多囊卵巢综合征的相关性研究

目的探讨微量元素锌与多囊卵巢综合征之间的关系。方法将100例多囊卵巢综合征患者和100例月经正常妇女分为观察组和对照组,采用原子吸收光谱法分别检测其血清和头发中微量元素锌的含量,并对其检测结果进行统计学分析。结果观察组血清及头发中的锌含量明显低于对照组,差异显著有统计学意义(P<0.05)。结论多囊卵巢综合征的发病可能与微量元素锌的缺乏存在一定的关系。     

小学生近视与发中铜铁锌含量的相关性研究

目的:通过对小学生发中铜、铁、锌含量分析,研究其含量变化与近视之间的相关性,为预防近视提供依据。方法:采用随机抽样方法在包头市东河区牛桥街小学抽取187例视力正常小学生(非近视组)和142例近视小学生(近视组),采集发样,清洗和消化处理后用火焰原子吸收分光光度法对其进行铜、铁、锌的含量测定。结果:近视组小学生发中Cu含量高于视力正常组,Fe和Zn的含量低于视力正常组,差异均有统计学意义(P<0.05);近视组小学生发中Cu/Fe比值和Cu/Zn比值比非近视组升高,差异有统计学意义(P<0.05),而Fe/Zn差异无统计学意义(P>0.05)。结论:小学生近视与发中Cu、Fe、Zn的含量有相关性。     

硫酸锌治疗小儿厌食症等109例疗效观察

自1986年5月至1986年11月我院儿科及保健门诊应用硫酸锌治疗观察小儿厌食症等109例。治疗组84例,对照组25例,两组于治疗前后均做了血锌含量测定。其中治疗组血锌值均低;经补锌治疗后食欲明显增加,症状显著改善,对照组全部无效。4岁以上患儿均做了味觉敏感度实验,治疗后味觉均有显著提高,药物治疗过程中副作用极小。     

Relationship between height, collagen metabolism, hair zinc and excessive fluoride intake]

After eliminating confounding factors, the study was made on the relationship between height, collagen metabolism, hair zinc and excessive fluoride intake. 140 schoolchildren aged 12-13 years born and reared in endemic fluorosis areas were surveyed. The results were as follows: 1. The average height of children with dental fluorosis III degree (DF III degree) was appreciably smaller than that of children without dental fluorosis. Among children with excessive fluoride intake, a negative correlation between the height and fluoride level in staple foods was seen. 2. The more the fluoride ingested, the higher the urinary THP excreted, showing that fluoride intoxication interfered with the collagen metabolism. 3. Among children with excessive fluoride intake, the height showed negative correlation with urinary THP/Cr, suggesting that the effect of fluoride on collagen metabolism indicated the mechanism of height retardation. 4. As compared to control group with the excessive fluoride intake but without dental fluorosis group, there was a significant reduction in hair zinc in group with DF III degree, suggesting that the zinc in the body decreased because of zinc metabolism disturbance by excessive fluoride intake. But among cases with excessive fluoride intake, no appreciable correlation between hair zinc and height was found. Therefore, it could not be confirmed that the effect of fluoride on zinc metabolism affected the height development.     

Effective treatment of Wilson's disease with oral zinc sulphate: two case reports

Most patients with Wilson's disease are treated with the potentially toxic cupriuretic agent penicillamine. The toxicity of zinc taken by mouth is low, and long term administration induces a negative copper balance. Two patients with severe neurological symptoms were given zinc sulphate by mouth three times daily in doses of 200 mg, later increased to 300 mg. One patient, a 21 year old man, started to receive zinc sulphate after his condition had deteriorated during treatment with cupriuretic drugs. The other, a 27 year old woman, was treated from the start with zinc sulphate. The conditions of both patients improved appreciably, and they were still receiving treatment with zinc sulphate roughly two years later. Effective depletion of body copper stores was shown by an intravenous radiocopper loading test and liver biopsy. No side effects were found. Wilson's disease may effectively be treated with zinc sulphate alone.     

1000例小儿发锌临床分析

微量元素锌与儿科常见疾病症状有一定关系。从１９９２年１月～１９９４年１２月三年间，我院儿科门诊做了１０００例小儿发锌资料分析。年龄３８天～１３岁。男性５３１例，女性４６９例。从分析中看出，发锌值在不同年龄段表现不同。１岁以内小儿高锌多于低锌，而－９岁组锌值低的多。发锌值异常与反复呼吸道感染、食欲低下有一定关系。说明了发锌检查在临床上有一定指导意义，且方便、易行。     

食管癌高发区正常人群头发中微量元素的变化趋势

目的了解食管癌高发区不同年龄段正常人群头发中微量元素含量及变化趋势。方法随机抽取林州市２５岁以上正常居民１２０名，按年龄分组，用原子吸收分光光度计（火焰法）和荧光法测定头发中铜、锌、钙、铁、硒等微量元素。结果林州市不同年龄组正常居民头发中锌、钙含量随年龄的增长，含量逐渐降低。相关系数分别是锌：ｒ＝－０．９０４２，钙：ｒ＝－０．９３８１，Ｐ均小于０．０１。铁元素在５５岁以下没有明显变化，５５岁以上显著降低，Ｐ＜０．０１。铜元素的变化是青年组较低，中年组略有升高，到５５岁以后又降低。硒元素除青年组与５５岁以上组有差别外，其余均无差异，Ｐ＞０．０５。结论头发中微量元素锌、钙、铁、硒等元素在５５岁以上的人群中均有明显降低，铜锌比例不稳定     

三硝基甲苯中毒性白内障患者头发中五种元素的分析

本研究采用原子吸收分光光度法对三硝基甲苯中毒性白内障患者头发中５种元素进行了分析。结果表明：中毒性白内障患者发钙、锰、铁含量显著增加（Ｐ＜０．０１）。锌含量显著降低（Ｐ＜０．０１），钙、锌变化与白内障期别直线相关（ｎ＝７０，ｒ分别为０．５９，－０．５８），元素比值明显改变。并就中毒性白内障的形成与各元素变化的关系进行了理论性探讨。     

Topical zinc sulphate solution for treatment of viral warts

OBJECTIVE: To assess the efficacy and safety of topical zinc sulphate solution in the treatment of plane and common warts. METHODS: This study consisted of a pilot and double blinded clinical trails. This was carried out in the Department of Dermatology and Venereology, Baghdad Teaching Hospital, Baghadad, Iraq during the period from December 2002 to October 2003. Ten patients with plane warts were enrolled in pilot-clinical trial, all patients used 10% w/v zinc sulphate solution topically, 3 times daily for 4 weeks while in the double blind trial, 90 patients were included (50 patients with common warts, 40 patients with plane warts). Patients were randomly used either topical 10% or 5% zinc sulphate solution or distilled water as a control topical therapy 3 times daily for 4 weeks. Full history and close clinical examination were performed to all patients before treatment. RESULTS: In the pilot trial, the full response for plane warts was 80%, while the full response for patients with plane warts in double blinded trial was 85.7%, 42.8% and 10% for those using 10% and 5% zinc sulphate solutions and distilled water subsequently. The difference was statistically significant (p<0.008). The full response for patients with common warts were 11%, 5% and 0% for those who used 10% and 5% zinc sulphate solutions and distilled water respectively, the difference was statistically insignificant. No recurrence of warts occurred during follow up that ranged from 2-6 months after therapy. CONCLUSION: Topical 10% zinc sulphate solution was a new effective and safe modality for treatment of plane warts.     

儿童发锌与智力的关系

本文研究儿童头发中微量元素锌与智力的关系,发现低锌率为39.05％,儿童发锌含量与智力密切相关。缺锌可提示智力低下,对临床删除儿童低锌引起智力低下的疾病有一定意义。建议合理安排儿童饮食并及时给缺锌儿童补锌,以促进其身体与智力的发育。     

16个民族21个群体HLA遗传距离分析

收集整理了国内壮、瑶、侗、苗、京、羌、鄂伦春、朝鲜、藏及东乡等15个少数民族和6个汉族群体的HLA基因频率资料,用Nei氏法计算出他们之间的遗传距离,并根据遗传距离按Sneath和Sokal氏聚类原则绘制出系统树。结果发现这些人群之间的遗传距离和系统树所表示的血缘关系与人类学家及历史学家研究的结果基本上一致。     

正常生育者与不育者精液、血清、头发中锌、铜、铁含量的测定及其意义的探讨

本文测试了53例正常生育男子与92例不育男子的精液、血清、头发中锌、铜、铁的含量,发现不育男子的精锌低于正常生育者,发锌与男子生育或不育无相关性,根据精液无精子的患者其精锌值不低于正常生育者的测试结果,提出精子密度与精锌值无相关性,并提出精液液化差与液化不全或前列腺炎症常是促使精锌降低的原因等看法。不育男子的精液、血清、头发中铜、铁的含量均高于正常生育者应予以重视。     

苓参消痞汤辨证治疗胆汁反流性胃炎80例

目的:观察苓参消痞汤治疗胆汁反流性胃炎的临床疗效。方法:160例患者分为治疗组和对照组,治疗组采用苓参消痞汤加减,对照组采用西药治疗,30d为1疗程。结果:治疗组80例的有效率为87.5%,对照组的有效率为72.5%。结论:参苓消痞汤治疗胆汁反流性胃炎有较好的临床效果。     

华特灵治疗急性腹泻的临床观察

目的 :评价我院药研中心研制的新型消化道粘膜保护剂———华特灵治疗急性腹泻的效果。方法 :选取 6 9例成人急性腹泻患者 ,其中华特灵组 33例 ,分别与思密达组 2 0例、氟哌酸组 16例进行对照 ,比较各组间疗效。结果 :华特灵组疗效明显高于氟哌酸组 (P <0 .0 5 ) ,而与密达组相近 (P >0 .0 5 )。结论 :华特灵是治疗腹泻的有效药物之一 ,对其它消化道粘膜病变治疗前景令人鼓舞