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Introduction

Persistent ductus arteriosus (PDA) constitutes 5–10% of all inborn heart defects. In preterms born with body weight <1000 g is present even in 80%.Fast diagnosis and treatment of hemodynamically significant PDA (hsPDA) allows avoiding many complications. In pharmacological treatment of hsPDA conventionally inhibitors of cyclooxygenase (COX) are used but they may cause many side effects. That is why alternative methods are investigated. One of them is the use of paracetamol.

Aim of the study

The aim of our study was the assessment of effectiveness of paracetamol treatment of hsPDA in preterm neonates.

Material and methods

The study was performed in 10 preterm neonates, with hsPDA confirmed by echocardiography. 2 neonates were excluded from the study. In diagnosis we considered the width of arterial duct, presence of reverse flow in the descending aorta and clinical status of the patient. Paracetamol treatment was started after the cardiological confirmation of hsPDA, intravenously in dose of 15 mg/kg every 6 hours during 5 days +/- 2 days. In none of the patients included in our study side effects were observed.

Results

Effective treatment with paracetamol was observed in 62% studied neonates. In two of the remaining neonates treatment with ibuprofen was continued but the therapy also failed. In one contraindications of COX inhibitors treatment were present (thrombocytopenia). Eventually surgical ligation was performed in 3 of them.

Conclusions

Paracetamol can be used as an alternative method of treatment of hsPDA to ibuprofen.  相似文献   

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Introduction

Benign acute childhood myositis (BACM) is a rare syndrome occurring in children during the convalescent phase after influenza B. It is characterized by the sudden onset of calf pain, which causes difficulty to walk. Symptoms were relieved in one week. In epidemic season 2015/2016, influenza type B predominated in Poland. It could cause a high incidence of BACM in the whole country.

Objective

To evaluate parents’ and doctors’ disease perception and diagnostic and therapeutic methods used in the practice. To describe the clinical features of benign acute childhood myositis and recommend investigations.

Materials and methods

We performed a search of electronic database (PubMed) to identify information about BACM. We analyzed questionnaires obtained from the whole of Poland after an information campaign. We evaluated disease progression, patient-management, and parents’ attitude to influenza vaccination.

Results

We analyzed 68 questionnaires. Among all the reported cases of BACM, 70% occurred in boys; the average age was 6 years. Almost all children had flu-like symptoms in the period preceding the occurrence of BACM. Almost all patients (98.5%) complained about calf pain, some feet pain (12%), or thigh pain (6%). In all children, abnormal gait was noticed, and almost half refused to walk. 85.3% of children were examined by the physician; 31% of them had laboratory tests. In 19% of cases, the doctor suspected flu as the cause of the disease. Symptoms usually resolved after two or three days. No child was vaccinated against influenza.

Conclusions

Polish physicians are insufficiently familiar with the symptoms and causes of BACM. Every child with this diagnosis should be examined by a doctor and should have laboratory tests performed. This allows differentiating BACM from other diseases with poor prognosis. In the flu season, physicians need to consider BACM as a cause of altered gait. Pediatricians should recommend vaccination against influenza to their patients.  相似文献   

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Phimosis is a common problem in paediatric practice. The diagnosis of phimosis usually does not cause difficulties, but the treatment options are controversial, moreover than the improper management may contribute to the exacerbation of the problem. The aim of this study is to review current recommendations for phimosis management, in particular addressed to community paediatricians who are responsible for its diagnosis and treatment or patient's referral to paediatric surgeon/urologist.  相似文献   

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OBJECTIVE: To show the importance of severe hydroelectrolytic disorder as a consequence of previously undiagnosed chronic disease. DESCRIPTION: Case report of hyponatremic coma caused by adrenal crisis in a child with previously undiagnosed Addisońs disease despite suggestive clinical findings of this disease in the last four years. After correction of severe hyponatremia, mild hypovolemia, hypernatriuria and hyperkalemia, the differential diagnosis of this hydroelectrolytic disorder revealed an adrenal crisis resulting from a primary chronic adrenal insufficiency. Oral treatment with hydrocortisone was efficient in correcting the metabolic disorder and the patient was then discharged. COMMENTS: It is very important to highly suspect of Addisońs disease in order to avoid the dangerous consequences of late diagnosis such as severe hydroelectrolytic disorders and retarded growth and development.  相似文献   

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The article addresses the problem of the legal basis of the underage patient's discharge from the hospital. The authors discuss discharge from the hospital after completion of diagnostic and therapeutic procedures as well as on-demand discharge of a legal representative. The issue of the so-called disciplinary discharge is also discussed.  相似文献   

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Omphalocele and gastroschisis are the most common congenital abdominal wall defects. This article presents etiology and strategies in diagnostics and in prenatal and postnatal management in these disorders. There are similarities and differences between gastroschisis and omphalocele which are essential for correct patient management. Most abdominal wall defects are detected antenatally. Prenatal diagnosis may influence timing, route and location of delivery and it facilitates postnatal multidisciplinary approach.  相似文献   

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The article presents chosen legal aspects linked with the participation of a juvenile, who is over 16-years-old, in diagnostic and therapeutic process. Furthermore, an issue of juvenile's consent to have a health benefit has been raised. In this range, legal basis has been shown allowing the doctor to take a medical intervention when the juvenile does not give consent to it. What is more, the article discusses doctor's responsibilities while handing over the information about health condition to the juvenile. A problem of the patient's right to intimacy has been also taken up.  相似文献   

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Prim. Doz. Dr. Robert Strohal, Leiter der Dermatologischen Abteilung des LKH Feldkirch im Gespr?ch mit Dr. Renate H?hl. R.  相似文献   

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Pädiatrie & Pädologie - Alles spricht für die Kariesprophylaxe durch die richtige Verwendung fluoridhaltiger Zahnpasten: Sie ist effektiv, sicher und dringend anzuraten....  相似文献   

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In 1946 Lucas Kulczycki received his medical degree from the University of Edinburgh – Scotland, then after completing his military duties practiced in London. In 1950 emigrated to Canada to continue his medical studies and subsequently went to Boston where he started to specialize in treating children with a severe respiratory disease known as cystic fibrosis. In Boston he worked with dr Harry Shwachman to devise the Shwachman-Kulczycki scoring System (SKS) for determining the severity of the disease in cystic fibrosis patients. The Shwachman-Kulczycki Score is a tool still used by medical professionals today.Dr Kulczycki was very active in disseminating cystic fibrosis knowledge by participating in several national and international medical meetings.  相似文献   

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