共查询到20条相似文献,搜索用时 31 毫秒
1.
Svenne Diefenbacher Phillippa Lally Benjamin Gardner 《British journal of health psychology》2023,28(2):499-512
Objectives
Interventions promoting habitual fruit consumption have the potential to bring about long-term behaviour change. Assessing the effectiveness of such interventions requires adequate habit and behaviour measures. Habits are based on learned context-behaviour associations, so measures that incorporate context should be more sensitive to expected habit and behaviour changes than context-free measures. This study compared context-specific and context-free measures of fruit consumption habit and behaviour following a 3-week habit formation intervention.Design
Prospective online study (n = 58).Methods
Behaviour frequency was assessed across five timepoints, retrospectively (Time 1 [T1], T5) or via daily diary data (uploaded weekly at T2, T3 and T4). Habit strength was assessed before (T1) and immediately after the intervention (T4), and again 2 weeks later (T5). Analyses of variance were run, with time and context specificity as within-subject factors, and habit and behaviour frequency as dependent measures.Results
An interaction between time and context specificity was found in both analyses (habit: F(2,114) = 12.848, p < .001, part.η2 = .184; behaviour: F(2,114) = 6.714, p = .002, part.η2 = .105). Expected habit formation patterns 5 weeks post-baseline were only detected by the context-specific habit measure. Likewise, increased behaviour frequency was only found when the target context was specified (p's < .001).Conclusions
Assessments of purposeful dietary habit and behaviour change attempts should incorporate context-specific measurement. 相似文献2.
Jan Oldenburg Sigrid M Kraggerud Marianne Bryd?y Milada Cvancarova Ragnhild A Lothe Sophie D Fossa 《Journal of translational medicine》2007,5(1):70
Background
To assess the impact of polymorphisms in Glutathione S-transferase (GST) -P1, -M1, and -T1 on self-reported chemotherapy-induced long-term toxicities in testicular cancer survivors (TCSs). 相似文献3.
Immune checkpoint molecules soluble program death ligand 1 and galectin‐9 are increased in pregnancy 下载免费PDF全文
Elizabeth Ann L. Enninga Susan M. Harrington Douglas J. Creedon Rodrigo Ruano Svetomir N. Markovic Haidong Dong Roxana S. Dronca 《American journal of reproductive immunology (New York, N.Y. : 1989)》2018,79(2)
Problem
Pregnancy requires balance between tolerance to the haploidentical fetus and the mother's ability to mount immune responses. There are parallels to this phenomenon that occur in metastatic cancer. We assessed soluble program death ligand‐1 soluble PD‐L1 (sPD‐L1) and galectin‐9 in the blood of pregnant women during gestation as these molecules are highly involved in immune suppression during cancer.Method of study
Maternal blood was collected from 30 primigravida women at monthly intervals during pregnancy, delivery and 6‐week post‐partum. Blood was analyzed for sPD‐L1 and galectin‐9 concentrations by ELISA. Term placentas were collected in formalin and IHC was completed for PD‐L1 and galectin‐9 expression.Results
Maternal blood levels of sPD‐L1 (0.438 ng/mL) and galectin‐9 (1976 pg/mL) were elevated early in normal pregnancies compared to non‐pregnant controls (0.242 ng/mL and 773 pg/mL, respectively). sPD‐L1 increased throughout gestation, whereas galectin‐9 remained elevated until parturition; both proteins returned to control levels post‐partum. Women carrying male fetuses had significantly higher galectin‐9 levels, but not sPD‐L1, than those carrying females (2263 pg/mL vs 1874 pg/mL; P = .0005). Trophoblast cells of the term placenta coexpress galectin‐9 and PD‐L1.Conclusion
Immune‐regulatory molecules galectin‐9 and sPD‐L1 increased during pregnancy and may play a role in immune tolerance that is critical for the fetus. 相似文献4.
Masanobu Takao Toshinori Okinaga Wataru Ariyoshi Kenjiro Iwanaga Ikuo Nakamichi Izumi Yoshioka Kazuhiro Tominaga Tatsuji Nishihara 《Inflammation research》2011,60(9):861-867
Objective
The purpose of this study was to investigate the mechanism by which heme oxygenase-1 (HO-1) regulates inflammatory responses induced by mechanical stretch in human fibroblast-like synoviocyte (HFLS) cells. 相似文献5.
Dafna Bonneh-Barkay Guoji Wang Adam Starkey Ronald L Hamilton Clayton A Wiley 《Journal of neuroinflammation》2010,7(1):34
Background
CHI3L1 (YKL-40) is up-regulated in a variety of inflammatory conditions and cancers. We have previously reported elevated CHI3L1 concentration in the cerebrospinal fluid (CSF) of human and non-human primates with lentiviral encephalitis and using immunohistochemistry showed that CHI3L1 was associated with astrocytes. 相似文献6.
Philippe Hujoel Lars Hollender Anne-Marie Bollen John D Young Joana Cunha-Cruz Molly McGee Alex Grosso 《BMC medical imaging》2006,6(1):1-7
Background
The thyroid is among the more radiosensitive organs in the body. The goal of this study was twofold: (1) to evaluate age-related changes in what is exposed to ionizing radiation in the neck area, and (2) to assess thyroid shield presence in cephalometric radiographs 相似文献7.
Paul A. G. Forbes Ekaterina Pronizius Anja C. Feneberg Urs M. Nater Giulio Piperno Giorgia Silani Ana Stijovic Claus Lamm 《British journal of health psychology》2023,28(2):306-319
Objective
Social interactions are vital for our well-being, particularly during times of stress. However, previous studies linking social interactions to psychological outcomes during the COVID-19 pandemic have largely been retrospective and/or cross-sectional. Thus, we tested four preregistered hypotheses (H1–H4) concerning the real-time effect of social interactions on momentary changes in stress and mood during two COVID-19 lockdowns.Design
We used an ecological momentary assessment approach in 732 participants in spring 2020 (burst 1) and in a subsample of these participants (n = 281) during a further lockdown in autumn/winter 2020 (burst 2).Methods
Participants reported their stress and mood in a smartphone app five times per day for 7 days and indicated the nature and frequency of their recent social interactions.Results
Social interactions (H1) and their frequency (H2) improved momentary affect (e.g., social interactions increased mood valence: estimate = 2.605, p < .001 for burst 1). This was particularly the case for face-to-face interactions which, compared with other types of interactions, reduced momentary stress (e.g., estimate = −2.285, p < .001 for burst 1) and boosted mood (e.g., estimate = 1.759, p < .001 for burst 1) across both lockdowns, even when controlling for the pleasantness of the interaction and the closeness of the interaction partner (H3). We also show that individual differences in people's responsiveness to different social rewards modulated the impact of social interactions on momentary mood (H4).Conclusions
This study extends findings from cross-sectional and retrospective studies by highlighting the real-time affective benefits of social interactions during COVID-19 lockdown. The results have important implications for the (self-) management of stress and mood during psychologically demanding periods. 相似文献8.
Cansheng Zhu Zhaojun Xiong Xiaohong Chen Zhengqi Lu Guoyu Zhou Dunjing Wang Jian Bao Xueqiang Hu 《Inflammation research》2011,60(8):769-774
Objective
We aimed to investigate the regulation and contribution of vascular endothelial growth factor (VEGF) and sFlt-1(1–3) to human monocytic THP-1 migration. 相似文献9.
10.
Julie Lajoie Johanne Poudrier Marguerite Massinga Loembe Fernand Guédou François Leblond Annie-Claude Labbé Michel Alary Michel Roger 《Journal of clinical immunology》2010,30(1):90-98
Introduction
Understanding the genital mucosal immunity and the factors involved in linking innate to adaptive immunity is crucial for the design of efficient preventive strategies against human immunodeficiency virus (HIV)-1. 相似文献11.
Li Long Yanying Liu Shiyao Wang Yi Zhao Jianping Guo Ping Yu Zhanguo Li 《Journal of clinical immunology》2010,30(5):669-675
Objective
This study aims to explore the potential role of circulating Dickkopf-1 (Dkk-1) and osteoprotegerin (OPG) in evaluating erosive arthritis in systemic lupus erythematosus (SLE). 相似文献12.
Bardia A Tiwari SK Gunisetty S Anjum F Nallari P Habeeb MA Khan AA 《Inflammation research》2012,61(4):359-365
Objective
The present study was designed to investigate the role of X-ray cross-complementing group 1 (XRCC1) and apurinic/apyrimidinic endonuclease 1 (APE1) polymorphisms in apoptosis and the risk of ulcerative colitis (UC). 相似文献13.
Stefan Dold Matthias W. Laschke Yilin Zhau Martin Schilling Michael D. Menger Bengt Jeppsson Henrik Thorlacius 《Inflammation research》2010,59(4):291-298
Objective
Leukocytes mediate hepatocellular injury in obstructive cholestasis. The aim of the present study was to define the role of P-selectin glycoprotein ligand-1 (PSGL-1) in cholestasis-induced leukocyte recruitment and liver damage. 相似文献14.
Background
Chemokines are emerging as important mediators of CNS inflammation capable of activating leukocyte integrins and directing the migration of leukocyte subsets to sites of antigenic challenge. In this study we investigated the expression, release and binding of CCL2 (MCP-1) and CCL3 (MIP-1α) in an in vitro model of the human blood-brain barrier. 相似文献15.
Objective
To investigate the effect of serum amyloid A1 (SAA1) on global gene expression in macrophages derived from THP-1 monocytes. 相似文献16.
Zofia Szczuka Ewa Kulis Monika Boberska Anna Banik Maria Siwa Hanna Zaleskiewicz Nina Knoll Tracey A. Revenson Aleksandra Luszczynska 《British journal of health psychology》2023,28(2):451-466
Objectives
There are two alternative hypotheses regarding bidirectional associations between self-efficacy and planning in predicting health behaviour change: self-efficacy may establish planning (cultivation hypothesis) or planning may enable the formation of self-efficacy (enabling hypothesis). This study investigates the order in which these two social cognitions are linked in adult–adult dyads in the context of sedentary behaviours (SB).Design
A longitudinal study with 4 measurement points, spanning 8 months.Methods
A total of 320 dyads (age: 18–90 years) were enrolled. Dyads included a focus person (who received the recommendation to reduce SB and intended to change their SB), and their partners, who were willing to support the focus persons and intended to reduce their own SB as well. Data were collected at Time 1 (T1), Time 2 (1 week later, T2), Time 3 (T3, 2 months after T1) and Time 4 (T4, 8 months after T1). SB was measured with accelerometers at (T1 and T4). Mediation models with individual and dyadic reciprocal effects were tested with path analyses.Results
Only one indirect effect was found: A higher level of partners' SB reduction-specific self-efficacy at T2 was related to the focus person's more frequent planning to reduce SB at T3, which, in turn, predicted lower SB time among partners at T4.Conclusions
The findings provide partial support for the cultivation model (self-efficacy prompting planning) and for dyadic reciprocal associations in the context of SB time reduction among adult dyads. 相似文献17.
Objective
The aim of this study was to determine whether five polymorphisms of endoplasmic reticulum aminopeptidase 1 (ERAP1) confer susceptibility to ankylosing spondylitis (AS). 相似文献18.
Background
Although cyclooxygenases (COX) and prostaglandin E synthases (PGES) have been implicated in ischemic stroke injury, little is known about their role in intracerebral hemorrhage (ICH)-induced brain damage. This study examines the expression and cellular localization of COX-1, COX-2, microsomal PGES-1 (mPGES-1), mPGES-2, and cytosolic PGES (cPGES) in mice that have undergone hemorrhagic brain injury. 相似文献19.
Amy Wachholtz Howard Eisenson Ronette Kolotkin Ayako Suzuki 《International journal of behavioral medicine》2010,17(2):118-124