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浅表淋巴结细针吸取细胞学检查的价值--附117例病例分析 总被引:1,自引:1,他引:1
细针吸取细胞学诊断因其方法简便、创伤小而广泛应用于临床,为病理细胞学诊断开辟了新的领域,本总结了117例浅表淋巴结细针穿刺细胞学检查(fine-needle aspiration cytology,FNAC)检查结果,结合活检病理诊断资料,探讨FNAC对浅表淋巴结的诊断价值。 相似文献
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目的 评价细针吸取细胞学检查诊断软组织肿瘤价值。方法 对1999年—2002年用细针吸取细胞学(FNAC)诊断的软组织肿瘤195例进行回顾性分析。结果 细胞诊断组织良性肿瘤和恶性肿瘤的准确率分别为97.3%和93.2%;软组织恶性肿瘤细胞学诊断与组织学类型的符号率为73%。结论 细针吸取细胞学操作简便,病人无痛苦,有较大的使用价值。 相似文献
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乳腺癌细针吸取细胞学检查中细胞蜡块的应用价值 总被引:2,自引:0,他引:2
目的 探讨细胞蜡块(CB)切片检查在乳腺癌细针吸取细胞学检查中的应用价值.方法 对31例乳腺癌的FNAC、CB及手术后常规切片资料进行对照分析.重点对定性诊断、免疫组化及制片优良率情况进行比较.结果 乳腺癌FNAC阳性检测率为90.12%,优于CB的83.87%,二者联合应用可以提高检测准确率;然术前检测ER、PR、C-erbB-2CB相对于FNAC涂片有明显的优势,二者阳性率及优良率均有显著差异(P<0.05).结论 CB对术前检测ER、PR、C-erbB-2效果良好,同时具有简单、方便、不增加患者痛苦的优点. 相似文献
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循证病理学实践——细针吸取细胞学临床应用价值的综合评价 总被引:2,自引:0,他引:2
目的:进行循证病理学实践。运用循证医学方法综合评价细针吸取细胞学(FNAC)的临床应用价值。方法:收集我院1990年~2002年的FNAC材料2013例,诊断报告采用5级分类法,但为了便于统计分析,将E级和U级合并为良性,Ⅳ级和Ⅴ级合并为恶性,Ⅲ级为可疑。将有组织病理学对照的符合条件的850例FNAC纳入本文。采用循证病理学的重要方法Kappa分析、Youden指数、准确性、敏感性和特异性等进行FNAC临床应用价值的综合评价。结果:本组FNAC的Kappa值为0.94,Youden指数为0.94,准确性为96.9%,敏感性为97.5%,特异性为96.3%。结论:FNAC作为一种操作简便、安全省时、准确率高,费用低,并发症少的一种新方法,相对于需要手术切除,再作组织病理学诊断,FNAC应当是最佳的。 相似文献
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目的探讨乳腺癌针吸细胞学(FNAC)诊断准确性。方法分析1326例乳腺肿块针吸细胞学诊断,并与323例手术后病理组织学诊断结果对比。结果本组 FNAC 诊断敏感性为97.1%,特异性为97.3%,假阳性率为2.7%,假阴性率为2.9%,诊断符合为97.2%。结论乳腺肿块 FNAC 检查是一种实用价值很高的诊断方法。文中对影响 FNAC 诊断的因素进行了讨论。 相似文献
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目的 探讨乳腺癌针吸细胞学(FNAC)诊断准确性。方法 分析1326例乳腺肿块针吸细胞学诊断,并与323例手术后病理组织学诊断结果对比。结果 本组FNAC诊断敏感性为97.1%,特异性为97.3%,假阳性率为2.7%,假阴性率为2.9%,诊断符合为97.2%。结论 乳腺肿块FNAC检查是一种实用价值很高的诊断方法。文中对影响FNAC诊断的因素进行了讨论。 相似文献
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目的比较超声引导下甲状腺结节细针穿刺细胞学与粗针穿刺组织学检查的诊断准确率、敏感度、特异性及并发症。方法收集95例超声检查疑似为恶性甲状腺结节患者的98个结节,行超声引导下细针穿刺细胞学与粗针穿刺组织学检查,并经术后常规病理检查证实。比较两种方法诊断甲状腺结节的准确率、敏感度、特异性及术后并发症。分析结节直径大小与取材满意率、诊断准确率的关系。结果 (1)细针穿刺取材满意率89.8%,粗针为96.9%。细针穿刺细胞学诊断甲状腺结节的准确率、敏感度、特异性分别为86.4%、90.5%、82.6%;粗针穿刺组织学诊断为90.5%、91.7%、88.6%;(2)粗针穿刺并发症发生率高于细针穿刺(14.3% vs.2.0%,P<0.05);(3)结节直径≥1.0 cm时,粗针穿刺诊断准确率高于细针穿刺(P<0.05)。结论细针穿刺细胞学与粗针穿刺组织学检查在甲状腺结节良恶性诊断中可互相补充。 相似文献
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Cytomorphologic Patterns of Breast Lesions in Sudanese Patients: Lessons Learned from Fine Needle Aspiration Cytology
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《Asian Pacific journal of cancer prevention》2014,15(8):3411-3413
Background: Cytology for breast lesions is a safe, rapid and cost-effective with a high specificity and sensitivity.Objective: To determine the cytomorphologic patterns of breast lesions identified among a group of Sudanesepatients. Materials and Methods: This study included 759 patients undergoing either a fine needle aspirationFNA, nipple discharge (ND) smears or breast skin scraping (SS) at a cytology clinic in Khartoum. Clinical anddemographic data were reviewed. Stained smears were categorized into: inadequate sample, normal breast,benign lesion, suspicious, or malignant neoplasm. Results: Of the 759 cases, 734 (96.71%) were FNA, 18 (2.37%)ND and 7 cases (0.92%) SS. For 28 cases, FNA was done under ultrasound guidance. Females were 720 (94.86%).Benign lesions were 423 (55.75%) and 248 (32.67%) were malignant and 77 (10.14%) of smears were normalwithout any detected abnormality. Ten (1.31%) cases were suspicious for malignancy, and only one case (0.13%)was reported as inadequate. Most lesions were observed among the age group 30 years and above. Conclusions:Most patients investigated have benign lesions, one third of cytological smears were malignant. FNAC is a usefultool for investigating breast lesions in limited-resource settings. 相似文献
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Diagnostic Accuracy,Sensitivity, Specificity and Positive Predictive Value of Fine Needle Aspiration Cytology (FNAC) in Intra Oral Tumors
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《Asian Pacific journal of cancer prevention》2012,13(8):3611-3615
Objective: The objective of this study was to establish the diagnostic accuracy, specificity and sensitivity of fineneedle aspiration cytology(FNAC) for intra-oral tumors, comparing with histopathology as the gold standard.Materials and methods: Forty cases of FNA cytology from intraoral tumors was performed in AFID along withthe demographic data and clinical information and then diagnosed at AFIP, Rawalpindi. Then the cytologyresults obtained per FNAC were compared with the histopathological biopsy results of the same lesions. Thefollowing variables were recorded for each patient: Age, gender, site of biopsy, diagnosis. The data were enteredand analyzed using Open-epi version 2.0. Diagnostic accuracy, sensitivity, specificity, positive predictive value andnegative predictive value were calculated. Cohen Kappa was further applied to compare the agreement betweenthe biopsy and FNAC diagnoses. A p-value of < 0.05 was considered as statistically significant. Results: Among thetotal patients included in the study there were 24 males and 16 females, with a ratio of 1.5:1. Age of the patientsranged from 24 to 80 years with a mean of 52 years. A total of six sites were aspirated from the oral cavity withmaximum (11) aspirates taken from alveolar ridge. The results of FNAC revealed that there were 32 malignantand 8 benign aspirates. Confirmation through histopathological analysis came for 31/32 malignant cases whileone was falsely given positive for malignancy on FNAC. Among a total of 40 cases, 31(77%) cases diagnosed werefound to be malignant and remaining 9(23%) were benign. The FNAC results revealed 32 malignant and 8 benignlesions. Histopathology of the subsequent surgically excised specimen showed malignant lesions in 31(77%) andbenign in 9(23%) patients. As a whole, it was found that the absolute sensitivity for introral FNAC was 100%and specificity 89% with positive predictive value of 97% and negative predictive value of 100%. Conclusion:Cytological diagnosis was almost corroborative with final histopathological diagnosis in all cases, with very fewexceptions, exhibiting high diagnostic accuracy. 相似文献
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经纤维支气管镜行纵隔淋巴结穿刺活检的分析 总被引:1,自引:0,他引:1
目的:扩大经纤维支气管镜(纤支镜)穿刺活检(TBNA)的应用范围,明确肺癌纵隔肿大淋巴结及非肿大淋巴结的性质。方法:对58例肺癌患者CT扫描提示76个肿大的和未提示21个不肿大的淋巴结均行经纤支镜TBNA术。结果:肿瘤引起的纵隔肿大淋巴结占62%,非肿瘤引起的肿大淋巴结占38%,肺癌纵隔非肿大淋巴结转移率占14%。该方法灵敏度为97%,阴性率为3%。结论:该方法能明确肿瘤诊断分期,对手术及预后具有重要意义,具有可行性和可靠性,易于推广应用。 相似文献