ACP骨水泥型假体治疗老年股骨颈骨折

目的探讨ACP骨水泥型假体治疗老年股骨颈骨折的临床疗效。方法对84例老年股骨颈骨折患者采用ACP骨水泥型假体行人工双极股骨头置换术治疗。根据Harris评分和X线检查评估临床疗效。结果84例获均得随访,时间6~36(18±3.5)个月。患者髋关节功能恢复好,未发现髋内翻及脱位。早期感染2例,经彻底清创更换假体后恢复良好。术前下肢彩超发现肌间静脉丛血栓4例,术后下肢彩超发现肌间静脉丛血栓10例、胫后静脉血栓2例,肌间静脉丛血栓抗凝后复查无血栓加重,胫后静脉血栓治疗后复查血栓吸收。髋关节功能Harris评分:优63例,良16例,差5例。结论 ACP骨水泥型假体治疗老年股骨颈骨折,可早期下地负重行走,恢复心肺功能,提高生活质量。围手术期积极的抗凝治疗可减少下肢静脉血栓发生。     

下肢骨折术前深静脉彩超与下腔静脉滤器防控肺栓塞的临床意义

目的探讨下肢骨折术前常规下肢静脉彩色多普勒超声筛查出深静脉血栓形成(DVT)后放置下腔静脉滤器预防致命性肺栓塞(PE)的临床意义。方法自2011-05—2013-11诊治中老年下肢骨折124例,骨折部位:骨盆骨折5例,髋部骨折48例,膝关节周围骨折15例,股骨干骨折22例,胫骨伴或不伴腓骨骨折19例,下肢多发骨折15例。所有患者在手术当天早晨,一般于术前0.5~3.0 h到B超室进行下肢动脉及静脉血管彩色多普勒超声检查。筛查发现下肢DVT后,停常规手术,急诊置入下腔静脉滤器后再完成骨折手术。结果 124例中出现DVT 24例,均为新发生的血栓。血栓部位:患侧髂静脉、股静脉、腘静脉及小腿深静脉均充满血栓者1例,双下肢股静脉、腘静脉及小腿深静脉血栓者2例,单纯患肢股静脉16例,单纯患肢腘静脉5例。4例未放置下腔静脉滤器,其中1例拒绝放置滤器自动出院,3例要求溶栓及抗凝治疗,错过骨折最佳手术时机。20例成功放置下腔静脉滤器,当日及次日进行骨折手术。9例术后3周内取出滤器;4例滤器上有大量血栓栓子,血栓拦截成功,避免了PE,滤器不予取出;7例在明确留置滤器利弊后自愿选择终生留置滤器。结论下肢骨折患者术前血管彩色多普勒超声检查出下肢DVT后急诊放置下腔静脉滤器,然后再进行骨折手术,可避免PE及猝死风险,为下肢骨折手术治疗提供安全保障。     

老年股骨颈骨折全髋关节置换术围手术期下肢深静脉血栓形成的特点

目的探讨老年股骨颈骨折行人工全髋关节置换术及规范化预防性抗凝治疗下围手术期下肢深静脉血栓形成的特点。 方法回顾性分析2015年1月~2017年6月华中科技大学同济医学院附属普爱医院骨科行人工全髋关节置换的老年患者363例,年龄（66±5）岁,男性114例（31.4%）,女性249例（68.6%）。将患者分为股骨颈骨折组（n=187）和非股骨颈骨折组（n=176）。按照《中国骨科大手术静脉血栓栓塞症预防指南》进行规范化血栓预防,对围手术期出现下肢深静脉血栓的患者进行回顾性分析,对比两组患者围手术期深静脉血栓形成的特点。 结果骨折组患者中8例出现下肢深静脉血栓,其中2例并发肺栓塞;非骨折组中6例出现下肢深静脉血栓,其中1例并发肺栓塞,差异无统计学意义（χ²=0.185,P>0.05）。骨折组下肢深静脉血栓5例发生于术前,3例发生于术后;非骨折组6例患者均发生于术后,两组比较差异有统计学意义（P<0.05）。 结论老年股骨颈骨折全髋关节置换患者术前和术后均易形成下肢深静脉血栓,对于这类特殊的群体,术前血栓防治也应引起足够的重视。     

初次髋膝关节置换术后静脉血栓发生情况的观察比较

目的 :通过对大样本的初次全髋、膝关节置换术患者的资料进行统计分析,描述初次髋、膝关节术后静脉血栓的发生率及解剖分布。方法:纳入2013年12月至2014年12月行初次全髋、膝关节置换术1 686例患者,其中THA 928例,TKA 758例。所有患者术前、出院前常规行双下肢静脉彩超,术中常规使用抗纤溶药,术后抗凝14 d。统计分析术后血栓发生类型及其解剖分布。结果:初次全髋关节置换术患者928例,30例出现血栓,27例为孤立性肌间静脉血栓,其次为累及腓静脉或胫后静脉的周围性血栓,无中心型血栓发生。初次全膝关节置换术患者758例中,87例出现血栓,81例为周围型血栓,4例为中心型血栓,其余2例为混合型血栓;74例的血栓累及单支静脉,65例累及肌间静脉、4例股静脉、3例胫后静脉、2例浅静脉;13例的血栓累及多支静脉,多累及肌间静脉、胫后静脉、腓静脉、静脉中的2支或3支。对比结果发现,全膝关节置换术后血栓发生率较高,差异有统计学意义(P0.001),且更容易出现中心型血栓及多支静脉受累。结论:在现代血栓预防措施的干预下,初次髋、膝关节置换术后血栓发生率较低,其发生率及解剖分布存在差异。     

下肢骨折术前彩超确诊下肢深静脉血栓15例

本院自2011年8月～2012年6月应用彩色多普勒超声技术对下肢骨折患者术前常规进行双下肢静脉检查,共发现下肢深静脉血栓15例,现报道如下。1临床资料1.1一般资料:回顾性分析伤后数小时至术前2周的下肢骨折患者     

桃红四物汤联合髋关节置换术治疗老年股骨颈骨折的临床研究

目的:探讨对老年股骨颈骨折患者应用桃红四物汤联合髋关节置换术治疗的疗效。方法:选取我院 2018年 7 月—2020年 2月收治的 85例老年股骨颈骨折患者,依据治疗选择的方法不同,分为观察组(应用髋关节置换术 +术后常规治疗与桃红四物汤中药, 43例)和常规组(应用髋关节置换术 +术后常规治疗, 42例);评价两组术前及术后 12周的血清相关指标胰岛素生长因子 -1(IGF-1)、分泌型蛋白骨硬化蛋白( SOST)水平、骨密度(股骨颈、 Wards三角区、大转子)、髋关节功能 Harris评分、步行能力评分、肢体运动功能 FMMS评分及并发症发生情况。结果:术前两组血清 IGF-1、 SOST水平、股骨颈、 Wards三角区、大转子三个部位的骨密度、 Harris评分、步行能力评分、 FMMS评分比较均无明显差异(P＞ 0.05)。术后 12周,观察组血清 IGF-1水平、股骨颈、 Wards三角区、大转子三个部位的骨密度含量、 Harris评分及 FMMS评分均高于常规组;观察组血清 SOST水平、步行能力评分均低于常规组;观察组下肢静脉血栓、假体松动等并发症发生率均低于常规组,差异均有统计学意义( P＜ 0.05)。结论:老年股骨颈骨折患者应用桃红四物汤联合髋关节置换术治疗,不仅能加快骨折的愈合与髋关节功能的恢复,还能减少下肢静脉血栓、假体松动等并发症发生比例,提升临床疗效,有一定的临床价值。     

下肢深静脉血栓位置与下肢骨折部位的关系

目的探讨下肢骨折患者静脉血栓位置与下肢骨折部位的关系。方法我院创伤骨科2017年1月至6月单侧下肢骨折、且彩超检查出有下肢静脉血栓的患者93例,观察血栓发生的左右侧是否与骨折左右侧一致,并观察血栓的具体位置,了解血栓分布的具体特点。结果 93例患者中有75例(80.63%)深静脉血栓发生在骨折肢体同侧。下肢深静脉血栓发生在骨折肢体同侧的相关系数为r=0.67,为正相关,显著相关。93例患者共检出下肢深静脉血栓146处,其中肌间静脉血栓80处(54.79%),明显高于其他部位发生血栓的比例。结论下肢骨折发生后,血栓一般发生在骨折同侧,发生于小腿肌间静脉丛的血栓明显高于发生于其他位置的血栓。     

髋关节置换治疗脑卒中股骨颈骨折临床效果观察

目的观察和分析人工关节置换治疗脑卒中患者偏瘫侧股骨颈骨折的疗效。方法 2006年6月~2010年5月,共收治脑卒中股骨颈骨折患者21例,均采用髋关节外侧切口入路,全部采用骨水泥型人工关节假体,行半髋双极人工股骨头置换术治疗,术后尽早恢复半坐卧位,常规抗感染及原发病的治疗。麻醉失效后进行下肢肌肉等长收缩、髋关节主动及被动活动,运用低分子肝素钙预防深静脉血栓1周。结果所有病例随访时间1年~4年2个月,平均2年,16例髋关节功能在术后2~4.5月(平均3个月)恢复至近似于受伤前的状态,4例髋关节功能较之前稍减退,1例死亡。结论对脑卒中股骨颈骨折患者,术前充分评估,积极治疗基础疾病,掌握好适应证,选择肌力3级以上的患者行双极人工股骨头置换可取得比较理想效果。     

经皮辅助关节囊入路治疗老年股骨颈骨折的早期疗效

目的探讨经皮辅助关节囊(SuperPATH)微创入路初次人工股骨头置换术治疗老年股骨颈骨折的可行性及早期疗效。 方法回顾性分析2015年10月年2016年11月期间,在仪征市人民医院骨科严格按照纳入和排除标准收集的老年股骨颈骨折,采用SuperPATH微创入路初次人工股骨头置换,共纳入患者21例,其中男5例,女16例;左髋6例,右髋15例;平均年龄为(74±9)岁。观察切口长度、手术时间、术中出血量及并发症等情况。采用髋关节Harris评分标准评定术前、术后3 d及术后3个月患髋功能。计量资料用W检验观察数据是否成正态分布;髋关节Harris评分采用重复测量的方差分析比较,组间两两比较采用t检验。 结果21例患者均获3～6个月随访。手术切口平均长度(7.0±1.5)cm,住院平均时间(9.6±1.8)d,手术平均时间(64±13)min,术中平均出血量(138.7±30.5)ml,下床负重活动平均时间(2.4±0.8)d。患者随访期限内均未发生皮肤坏死、感染、骨折、深静脉血栓(DVT)、关节脱位及下肢不等长等严重并发症。术后3 d患侧髋关节Harris评分平均为(67.3±6.3)分,与术前(12.1±4.3)分比较差异有统计学意义(t＝23.132,P<0.05);术后3个月患侧髋关节Harris评分平均为(84.7±4.5)分,与术后3 d比较差异有统计学意义(t＝9.075,P<0.05)。 结论SuperPATH微创入路初次人工股骨头置换术治疗老年股骨颈骨折早期疗效有明显优势,具有创伤小、切口小、出血少、术后疼痛轻、可早期下床、患者满意度高,能降低术后关节脱位等并发症,符合微创外科和快速康复外科的发展理念。     

静脉内平滑肌瘤病的超声表现

目的观察静脉内平滑肌瘤病（IVL）的超声特征。方法回顾性分析4例经超声诊断并经手术病理证实的IVL患者的临床资料与超声声像图表现。结果4例IVL患者中,3例曾因子宫肌瘤而接受子宫切除术;3例病变累及髂静脉,其中2例出现下腔静脉受累;2例累及右心。2例于术后6个月接受随访,发现盆腔低回声结节。结论密切结合病史,熟悉超声图像特征,有助于诊断IVL。超声为IVL术后随访的首选检查方法。     

Thrombosis in unusual sites of the lower extremity veins

BACKGROUND: Thrombosis in unusual locations in the lower extremity veins has not been assessed. These veins are not imaged routinely and therefore information about them is lacking. METHODS: This study was designed to evaluate the natural history of deep vein thrombosis (DVT) in unusual sites. Patients with DVT in all thigh veins but the femoral vein were included. Patients with thrombi in any other vein in the first examination and those with history of DVT were excluded. Duplex ultrasound (DU) examination was performed to exclude thrombosis in the lower extremity in patients with signs and symptoms of venous thromboembolism and also in high-risk, asymptomatic patients. All veins from the distal external iliac vein to the lower calf were imaged. The deep femoral, femoropopliteal, lateral thigh, sciatic, and muscular thigh veins were examined. These patients were followed at 1 week, 1 month, 6 months, 1 year, and yearly thereafter, for thrombus propagation, resolution, and reflux. RESULTS: Among the 15,850 DU performed in the vascular laboratory at Loyola University Medical Center, in a 10-year period to rule out DVT, 2568 (16.2%) were positive and 14 cases (7 males, 0.54% among the patients with DVT and 0.088% among the entire population) involved thromboses in unusual locations. Ten cases involved the left lower extremity and four the right. The unusual DVT cases were associated with medical and surgical conditions or were idiopathic in 11 patients, whereas three had Klippel-Trenaunay syndrome (KTS). The veins involved in the first group of patients were the deep femoral (8), the femoropopliteal (2), and the deep external pudendal (1). The patients with KTS had involvement of muscular thigh veins (1), and the lateral thigh vein and the sciatic vein (2). Thrombi propagation with extension to the common femoral vein was seen in four of the 14 patients: two from the deep femoral vein, one from the femoropopliteal vein, and one from the deep external pudendal vein. There were two incidences of pulmonary embolism (PE) one of which was fatal. At final follow-up, two patients developed recurrent DVT and nine had signs and symptoms of chronic venous disease. CONCLUSIONS: The involvement of the studied veins in DVT is extremely rare. Thrombosis in these veins can follow the natural course of thrombosis in the more usual locations and is associated with lethal incidences of PE. Therefore, the association of these veins with all the grave sequelae of thromboembolic disease suggests that inclusion of these veins in routine lower extremity duplex scans would be beneficial.     

Utility of portable continuous-wave Doppler examination in screening for postoperative deep vein thrombosis

BACKGROUND: Early and accurate diagnosis of post-surgical deep vein thrombosis (DVT) can be difficult and time-consuming, even with duplex ultrasonography. Portable continuous-wave Doppler ultrasonography may be useful in screening patients for postoperative DVT. Further confirmation of Doppler-positive cases by duplex ultrasound might then be more cost-effective. METHODS: All major post-surgical patients from the departments of general surgery, orthopaedic surgery and colorectal surgery were screened on the third postoperative day for DVT by assessing the quality of the flow signal ("whoosh") obtained by placing the probe over the femoral vein and subsequently over the popliteal vein, both with a distal squeeze, as well as assessment of phasic flow with respiration. An absent or attenuated "whoosh" was judged to be suspicious for DVT and required formal duplex ultrasonography. The first 800 consecutive patients were studied to determine the sensitivity, specificity and accuracy of portable Doppler ultrasonography for DVT screening. RESULTS: Twenty-four cases of DVT were diagnosed, comprising seven cases in the proximal veins and 17 cases in the calf veins. The sensitivity of Doppler ultrasonography was 12.5% and the specificity was 96.8%. The positive and negative predictive values were 10.7% and 97.3%, respectively. CONCLUSIONS: Portable Doppler ultrasonography does not have adequate accuracy to be used as a quick screening tool for DVT.     

股骨骨折患者下肢深静脉血栓形成的流行病学特征研究北大核心CSCD

目的探讨股骨骨折患者下肢深静脉血栓形成(DVT)的流行病学特征。方法回顾性分析2019年1月至12月期间河北医科大学第三医院收治的2571例股骨骨折患者资料。男1079例,女1492例;年龄为14~96岁,平均67.1岁。骨折部位:股骨颈骨折1158例,股骨转子间骨折951例,股骨干骨折309例,股骨髁骨折153例。2414例患者行手术治疗,157例患者采用非手术治疗。手术患者术前及术后每周,非手术患者入院48 h内及住院期间每周均行双下肢彩色多普勒超声检查,判断DVT的发生情况。记录股骨不同部位骨折后DVT的发生率及发生位置。结果股骨骨折患者DVT发生率为35.5%(913/2571),近端DVT发生率为5.3%(135/2571),远端DVT发生率为30.3%(778/2571)。股骨颈骨折、股骨转子间骨折、股骨干骨折、股骨髁骨折患者DVT的发生率分别为28.8%(334/1158)、44.7%(425/951)、30.7%(95/309)、38.6%(59/153),近端DVT发生率分别为2.7%(31/1158)、5.6%(53/951)、9.7%(30/309)、13.7%(21/153),远端DVT发生率分别为26.2%(303/1158)、39.1%(372/951)、21.0%(65/309)、24.8%(38/153)。股骨骨折患者股静脉及以上部位、腘静脉、胫腓静脉、肌间静脉DVT发生率依次2.3%(60/2571)、2.9%(75/2571)、6.4%(165/2571)、23.8%(613/2571)。结论股骨骨折患者DVT发生率较高,而且发生肺栓塞风险性大的近端DVT更易发生于股骨髁骨折患者。     

髋部骨折患者术前静脉血栓栓塞症的预防与治疗

目的 分析髋部骨折患者深静脉血栓形成(DVT)的影响因素,探讨髋部骨折患者术前静脉血栓栓塞症的预防与治疗.方法 选取2008年6月至2010年6月间收治的531例髋部单发骨折患者,男242例,女289例;平均年龄59.2岁(28～93岁).股骨颈骨折336例,股骨转子间骨折183例,股骨转子下骨折12例.分析不同骨折类型、D-二聚体浓度、性别、年龄及术前制动时间与DVT发生率的关系.对于出现DVT的患者,给予放置下腔静脉滤器同时行骨折内固定术. 结果所有531例髋部骨折患者中,股骨颈骨折患者中21例发生DVT,股骨转子间骨折患者中34例发生DVT,股骨转子下骨折患者中无一例发生DVT.55例患者DVT均发生于术前,发生率为10.4%(55/531).髋部骨折患者年龄、性别对DVT的发生率无影响,差异无统计学意义(P值分别为0.347、0.376).D-二聚体浓度、骨折类型和术前制动时间对DVT的发生率有影响,差异有统计学意义(P值分别为0.002、0.017、0.037).55例发生DVT的患者均顺利完成手术. 结论对于髋部骨折患者,年龄、性别对DVT的发生不具有临床意义,D-二聚体浓度、骨折类型和术前制动时间对DVT的发生有临床意义.放置下腔静脉滤器可确保骨折内固定手术及术后康复安全顺利进行.     

老年股骨颈骨折后下肢深静脉血栓发生情况及其危险因素分析

目的:探究老年股骨颈骨折后下肢深静脉血栓的发生率、血栓位置及相关危险因素。方法:回顾性分析天津南开医院和河北医科大学第三医院2017年1月—2019年6月收治的老年股骨颈骨折患者708例。入院后,对患者行常规超声多普勒扫描以评估患者双下肢是否有深静脉血栓,将有血栓者为病例组(112例),无血栓者为对照组(596例)。提取患者的临床资料,包括人口学信息、合并病、受伤情况和入院时实验室结果,采用单因素检验和二元logistic回归分析确定DVT发生的相关危险因素。结果:共112例(15.8%)患者诊断为DVT,84例(75.0%)为远端型,21例(18.8%)为近端型,7例(6.2%)为混合型DVT。75.9%(85/112)的患者DVT发生在骨折侧肢体,12.5%(14/112)发生于双侧肢体,11.6%(13/112)发生于未骨折侧。多因素logistic回归分析显示,年龄大、D-二聚体升高(>0.5 mg/L、受伤至入院时间长、血清白蛋白水平降低(<35 g/L)和血小板计数(>262×10⁹/L)是发生下肢深静脉血栓的独立危险因素。结论:老年股骨颈骨折患者入院时DVT发生率较高,近端DVT达到6%。多个相关危险因素与DVT独立相关。     

股骨颈骨折对人工髋关节术后深静脉血栓形成影响的病例对照研究

目的:探讨股骨颈骨折是否为髋部人工关节术后DVT的危险因素。方法:检索自2005年1月至2010年7月于北京协和医院接受人工髋关节手术的患者,排除不适合纳入研究病例,其余为候选病例。候选病例均在术前经B超检查除外DVT,在围手术期接受了规范的预防DVT治疗。对术后出现DVT或肺栓塞(PE)症状、体征者,通过相应影像学检查进行确诊。选取术后发生症状性DVT的患者作为病例组,以年龄、性别、体重作为匹配条件选取对照组病例。在病例组和对照组中,以股骨颈骨折为暴露因素,计算比值比(OR)并比较其暴露率,验证其关联强度。结果:在670例接受人工髋关节手术的患者中,408例为候选病例。其中13例术后发生症状性DVT作为病例组,男4例,女9例,平均年龄77岁(57～91岁),全部为股骨颈骨折患者。对照组52例中男18例,女34例,平均年龄76.98岁(57～91岁);其中39例因股骨颈骨折接受手术。病例组中股骨颈骨折的暴露率为100%(13/13),对照组为75%(39/52),2组暴露率差异无统计学意义。结论:尚不能认为股骨颈骨折是髋部人工关节术后症状性DVT的独立危险因素。股骨颈骨折的流行病学特征决定了其患病人群既是DVT的高危人群,也是接受人工髋关节手术的主要人群。人工髋关节手术可以降低股骨颈骨折的DVT风险,与手术本身的DVT风险增加相平衡,故股骨颈骨折患者术后DVT风险较非股骨颈骨折患者并未显著升高。     

Incidence and distribution of lower extremity deep vein thrombosis in rehabilitation patients: implications for screening

Patients admitted to in-patient rehabilitation programs have an increased risk for developing deep venous thrombosis (DVT). However, the utility of screening for lower extremity DVT using duplex ultrasound in this high-risk population is not well characterized. The purpose of this study is to identify whether or not screening lower-extremity duplex exams are indicated in this high-risk population. Screening lower extremity duplex exams were performed on all patients admitted to the rehabilitation center at Mt. Sinai Hospital over a 3-year period. Charts were reviewed for patient age, gender, diagnosis, date of screening and follow-up duplex exams, presence and location of venous thrombosis at each duplex exam, history of anticoagulation, and medical DVT prophylaxis. The presence of DVT at screening, the location of DVT along the lower extremity, and the outcome of calf DVT were analyzed in terms of gender, underlying diagnosis, and history of DVT prophylaxis. Lower extremity DVT was detected in 34% of patients. Twenty-three percent of patients had isolated calf vein thrombosis. Men were more likely than women to have DVT. Calf DVTs progressed in 3% of patients over an average follow-up of 2 weeks. The presence of DVT, its location along the lower extremity, and the outcome of calf vein DVT had no significant relationship to underlying diagnosis or history of prophylaxis. Screening duplex exams to detect lower extremity DVT in rehabilitation patients is useful. Screening altered management in 26% of patients, prompting either anticoagulation or repeat duplex exam.     

Proximal extent of pelvic vein thrombosis and its association with pulmonary embolism

OBJECTIVE: Conventional methods such as duplex ultrasound scanning do not provide accurate information about proximal extension of pelvic vein thrombosis. We evaluated proximal extent of thrombus toward pelvic veins with magnetic resonance imaging in patients with suspected deep vein thrombosis (DVT) proximal to the inguinal ligament on the basis of duplex ultrasound scans. In addition, frequency of pulmonary embolism (PE) and early (4 weeks) clinical outcome were evaluated. METHODS: Two hundred twelve patients with acute symptomatic DVT proximal to the inguinal ligament, diagnosed at duplex ultrasound scanning, were enrolled in this prospective study. All patients underwent magnetic resonance imaging of the abdominal and pelvic veins, as well as lung scintigraphy to detect the presence of pulmonary embolism. RESULTS: In 24 of 212 patients (11%), thrombus was restricted to the femoral vein. The thrombus extended into iliac veins in 142 patients (67%) and into the inferior vena cava in 46 patients (22%). The frequency of PE was not associated with the most proximal extension of thrombus (P =.61). No patients died as a consequence of thromboembolic events. CONCLUSIONS: Extension of DVT into the inferior vena cava occurs relatively frequently. In our patients this finding was not associated with higher risk for PE compared with DVT of the femoral or iliac veins.     

Renal allograft loss due to proximal extension of ileofemoral deep venous thrombosis

Renal allograft recipients with thrombophilic (hypercoagulable) states are at higher risk for early allograft loss. Presumably, the combination of endothelial injury at surgery and thrombophilia predisposes to arterial or venous thrombosis. Of 270 consecutive renal transplants at our center one allograft failed secondary to renovascular thrombosis. At exploration the iliac and renal veins were thrombosed. Thrombectomy and re-implantation were attempted, but unsuccessful. Also noted at surgery was extensive clot in the femoral vein that could not be removed by embolectomy catheters. Post-operatively, a Doppler ultrasound confirmed the presence of extensive deep venous thrombosis (DVT) in the femoral and popliteal veins. The adherent nature of this clot, the extent of clot found less than 12 h after renal transplantation and the absence of leg edema suggested that the DVT existed prior to surgery. This case demonstrates that a pre-existing, asymptomatic DVT can precipitate allograft thrombosis and highlights the importance of diagnosing thrombophilia in patients undergoing renal transplantation. Current practices in our unit have evolved to include screening for thrombophilia in all patients with a suggestive history. As thrombophilic states are increasingly appreciated in the end-stage renal disease population, effective management of these patients while on hemodialysis and at the time of renal transplantation presents an ongoing challenge.