生命质量8条简明量表中文版开发及其性能评价

[目的]开发用于测量生命质量的8条目简明量表（SF-8）中文版本，并检验其信度和效度。[方法]采用翻译与回译两个步骤开发SF-8中文版本：采用现况调查用SF-8中文版本测量部分成都市居民生命质量，计算量表的内部一致性信度，并以SF-36为校标计算SF-8量表的校标效度，运用因子分析评价其结构效度。[结果]SF-8量表的克朗巴赫α系数为0．749；SF-8量表测量结果与SF-36的总分相关系数为0．559，各维度相关系数范围在0．339～0．539之间；因子分析共提取出3个公因子，即心理健康、生理健康和总体健康，累计贡献率为71．71％。[结论]SF-8量表具有较好的信度和效度，可以在中国人群中应用。但在应用时也要注意调查对结果灵敏度的要求。     

SF-36量表在中国老年人群中应用的心理学特征测评

目的研究简明健康调查问卷(SF-36)量表应用于我国老年人群时的心理学特征。方法采用SF-36对1 128名社区老人(60岁及以上)进行面对面问卷调查。估计量表在样本人群中的信度和效度。结果 SF-36用于评价我国老年人群生存质量的分半信度为0.919(子维度分半信度范围0.664~0.916),总量表Cronbach'sα系数为0.914(子维度系数范围0.738~0.943)。此外,相关性分析结果显示,各条目与其所在子维度间相关系数显著高于与其他维度间相关系数。结论 SF-36在该研究的样本中表现出了良好的信度和效度,说明它可用于我国老年人健康状况的测量。     

中文版SF-36量表在浙江省老年人群健康生命质量评价中的信度和效度

目的 评价中文版SF-36量表在老年人群健康生命质量评价中的信度和效度.方法 2007年10-12月统一受训的调查员使用含中文版SF-36量表的问卷对浙江省城乡4241名60周岁以上的老年人面对面询问式调查,采用相关分析、信度分析、因子分析、t检验和方差分析等统计学方法 评价量表的信度和效度.结果 中文版SF-36量表具有较好的分半信度(r=0.91,P<0.001),内部一致性信度α系数除生命活力(α=0.65)、社交功能(α=0.65)、心理健康(α=0.40)维度外,其余维度的α系数均>0.8.每个条目跟相关维度的相关系数均>0.4(条目9-2除外),且高于该条目与其他维度的相关系数(条目9-8除外),说明中文版SF-36量表有良好的集合效度和区分效度.35个条目在提取的6个公因子中的分布与量表的理论结构假设基本一致,累计贡献达67.04%.除心理健康维度外,各维度具有良好的判别效度.结论 中文版SF-36量表有较好的信度和效度,适用于老年人群健康生命质量评价,但量表心理健康维度的信度与效度较低,且其中的9-2、9-8以及躯体功能维度中的3-1条目不适合于中国老年人群.     

国人生活质量普适量表的编制与评价

目的编制适合中国一般人群的生活质量普适量表并评价该量表的信度和效度。方法参照世界卫生组织生活质量量表（WHO-100）和美国医学结局健康状况调查问卷（SF-36），并结合中国人群社会文化特点编制生活质量普适量表（QOL-35），包括35个条目，分别属于总体健康和生活质量、生理功能、独立生活能力、心理功能、社会功能、生活条件6个领域和1个反应生活质量变化的条目。对127名社区成人的生活质量进行间隔24—72h的重复调查，评价量表的重测信度。对135名门诊或社区人群同时应用WHO-100、SF-36和QOL-35，比较QOL-35与国外标准量表的内部一致性信度和结构效度。在1356名社区人群中评价QOL-35的稳定性和适用性。结果（1）重测信度：QOL-35量表各条目2次测量之间权重一致性（Kappa值）范围为0．86～1．00，各领域和整个量表在2次测量之间的组内相关系数范围为0．68～0．94。（2）内部一致性信度：QOL-35、WHO-100和SF-36量表的克隆巴赫a分别为0．93、0．97和0．89。（3）结构效度：三个量表经因子分析选出的前7个因子方差累计贡献率分别为66．5％、50．3％和65．3％。（4）标准效度：QOL-35总分与WHO-100总分和SF-36的总分Spearman相关系数分别为0．805和0．745。（5）判别效度：各种慢性病总患病率在QOL-35总分第一到第四分位人群中分别为53．1％、33．1％、26．4％和25．1％（P〈0．05）。（6）QOL-35在1356名一般人群的初步应用显示出近似的克隆巴赫α。结论QOL-35具有较好的重测信度，与WHO-100和SF-36相比以较少的条目获得较好的结构效度、内部一致性和判别效度，在较大人群的初步应用显示出较为稳定的测量特性，QOL-35是评价中国一般人群生活质量较理想的工具。     

中文版SF-36量表应用于慢型克山病患者中的信度与效度评价

目的评价中文版简明健康状况调查表(SF-36量表)在慢型克山病患者生存质量调查中应用的信度与效度, 为该人群生活质量研究及治疗康复评价提供科学依据。方法 2017年8月, 采用整群随机抽样方法, 抽取甘肃省平凉市2017年家庭病床自我管理治疗的175例慢型克山病患者为调查对象, 收集人口学资料和病情资料;并采用中文版SF-36量表进行生存质量调查。应用分半信度和克朗巴赫α系数(Cronbach′s α系数)评价SF-36量表的信度, 因子分析法、相关性及组间差异分析评价SF-36量表的效度。结果 SF-36量表的分半信度值为0.916, Cronbach′s α系数为0.869。因子分析从SF-36量表的8个维度中提取出3个公共因子, 3个公共因子对总方差的累计贡献率为72.08%;除情感职能与躯体疼痛维度的相关系数(r)外, SF-36量表总得分与各维度得分及各维度得分之间的r值在0.140 ～ 0.769;除躯体疼痛维度外, 不同心功能分级患者的生存质量生理机能、生理职能、一般健康状况、精力、社会功能、情感职能、精神健康维度得分比较差异均有统计学意义(F = 4.66、10.73、...     

SF-36量表用于事业单位员工健康测量的信度与效度评价

目的对SF-36量表用于事业单位工作人员健康测量的信度与效度进行评价,为事业单位工作人员健康测量工具的开发或选择提供依据。方法应用SF-36量表对整群抽取的东莞市5家事业单位的员工进行调查,采用SPSS和LISREL软件对SF-36量表的信度与效度进行分析。结果 SF-36量表的整体克朗巴哈系数以及PCS和MCS两个领域8个维度各自的克朗巴哈系数均在0.70以上,Spearman-Brown分半信度系数为0.767。量表结构效度的二阶验证性因子分析模型拟合指数RMSEA为0.071,NNFI为0.90,CFI为0.91,一阶因子载荷标准解以及二阶因子载荷标准解均大于0.30,t检验的P<0.05。结论 SF-36量表用于事业单位员工健康状况测量具有较好的信度与效度,可以作为事业单位工作人员健康测量的工具。     

修改后的SF-36健康调查应用于老年人群的评价

目的 评价修改后的SF-36健康调查表在老年人群中的信度和效度。方法 采用面对面访谈形式调查老年人使用修改后的SF-36的情况，并与老年人生活质量调查内容的结果进行比较。结果 修改后的SF-36条目得分满足量表设计者确定的假定顺序；各标度的Cronbach＇s α系数是0．73～0．91。其中65～75岁组的信度好于〉75岁组老年人群；各年龄组的不同标度与总测量的关系满足原设计者的假定关系；修改后SF-36的两个总测量与老年人生活质量调查内容的一致性均较好。结论 修改后的SF-36健康调查具有良好的信度和效度，更适合于老年人群使用。     

SF-36量表评价新疆图瓦成人生命质量的信度效度

目的评价SF-36生活质量量表用于测量新疆图瓦成人生活质量的信度和效度。方法采用多阶段抽样的方法,于2016年在新疆阿勒泰地区哈巴河县白哈巴村和布尔津县喀纳斯、禾木村,随机抽取了437名图瓦成年人作为调查对象(男性227人,女性210人;18～29岁占30.66%、30～49岁占54.00%、≥50岁占15.33%)。使用SF-36量表评价生命质量,用内部一致性信度和折半信度评价量表信度;采用集合效度、区分效度和结构效度评价量表的效度。结果 SF-36量表的Cronbach’α系数为0.838,删除相应维度后的Cronbach’α系数均0.750。Spearman-Brown系数为0.828。集合、区分效度定标试验成功率分别为100%和99.59%。将35个条目纳入探索性因子分析,用最大平衡化旋转法提取7个公因子,累计贡献率为68.97%。将8维度纳入探索性因子分析,提取2个公因子,累计贡献率为66.44%。验证性因子分析模型拟合结果不理想。结论 SF-36量表用于评价新疆图瓦成年人生活质量有良好的信度、集合与区分效度,结构效度有待提高。     

SF-36量表在乙型肝炎患者生存质量测量中的可行性评价

目的评价SF-36量表在乙型肝炎患者生存质量测量中的可行性。方法对150例乙型肝炎患者的测量结果,考核量表应答率、Cronbach α系数、内容效度、结构效度和甄别力等进行评价。结果SF-36量表各维度的条目能被全部回答的比例范围是94.8%~97.8%,维度分数能被计算的比例范围是98.5%~100.0%;各维度Cronbach’sα系数范围是0.513~0.934;9I条目与VT维度的相关系数为0.334,其余大于0.4;VT维度与构想的生理健康强相关不一致;VT和MH维度不能表现出应该有的区别患者与正常人、疾病的严重程度上的差异。结论从总体上看SF-36量表用于测定乙型肝炎患者具有比较好的信度、效度,但不够全面。     

WOMAC、SF-36量表与《大骨节病治疗效果判定》(WS/T 79-2011)标准在大骨节病患者疗效评价中的应用比较

目的比较西安大略和麦克马斯特大学骨关节炎指数(WOMAC)量表、医疗结果研究36项简表(SF-36量表)与《大骨节病治疗效果判定》(WS/T 79-2011)标准在大骨节病患者疗效评价中的应用效果, 为大骨节病患者治疗评价提供依据。方法以甘肃省213名大骨节病患者为调查对象, 分别采用WOMAC、SF-36量表与WS/T 79-2011标准分析大骨节病患者治疗前后生活质量。比较WOMAC、SF-36量表的信度、结构效度、内容效度、区分效度, 并分析WOMAC、SF-36量表与WS/T 79-2011标准之间的相关性。结果 WOMAC、SF-36量表均具有较好的结构效度与内容效度(结构效度:WOMAC、SF-36量表分别含1、2个公因子;内容效度:WOMAC、SF-36量表分别含3、8个公因子);WOMAC量表的信度、区分效度均优于SF-36量表(信度:WOMAC量表信度系数均≥0.934, 而SF-36量表信度系数范围为0.386 ～ 0.999;区分效度:患者治疗前后WOMAC量表3个领域均有差异, 而SF-36量表8个领域中6个领域有差异)。WOMAC、SF-36量表与WS/T 7...     

Der deutsche SF-36 Health Survey Übersetzung und psychometrische Testung eines krankheitsübergreifenden Instruments zur Erfassung der gesundheitsbezogenen Lebensqualität

The SF-36 Health Survey is a generic instrument for the assessment of health-related quality of life developed as a short form of the instruments used in the Medical Outcome Study. Translation, psychometric testing and norming is currently ongoing in 15 countries including Germany, which are associated within the International Quality of Life Assessment Project (IQOLA). We report methods and results of the German translation and psychometric testing of the SF-36 with six samples of over 1500 healthy and ill persons. Results show that the use of the IQOLA study protocol led to a satisfactory German version of the SF-36 Health Survey and that psychometric testing yielded good to excellent results as concerns scale structure and reliability. The SF-36 Health Survey, which will be included in a norming study in 1995 thus appears as an instrument for health-related quality of life assessment applicable also in German studies.     

Psychometric properties of the Minnesota Living with Heart Failure—Brazilian version—in the elderly

BACKGROUND: Heart failure (HF) has implications for the quality of life for any age range, more so for the elderly who simultaneously present other limitations imposed by multiple co-morbidities. Although there are several instruments to measure Health Related Quality of Life (HRQL), none is specific to the elderly with HF. Among disease-specific instruments, Minnesota Living with Heart Failure(LHFQ) has not been studied extensively among the elderly with respect to its psychometric properties. OBJECTIVE: The purpose of this study was to evaluate the convergent, divergent and discriminative validity of the Brazilian version of LHFQ applied to elderly HF patients. METHOD: One hundred and seventy (170) elderly were interviewed. LHFQ capacity to discriminate subjects among New York Heart Association (NYHA) Classes I, II and III/IV was analyzed. Convergent and divergent validity was evaluated through the correlation between the domains of LHFQ and the generic instrument, Medical Outcomes Study (MOS) 36-item Short-Form Health Survey (SF-36). RESULTS: The LHFQ total score and physical dimension sub-scale discriminated between the three sub-groups of NYHA Classes I, II and III/IV (P < .0001). The emotional dimension discriminated NYHA Classes I and III/IV (P = .0034). The physical and emotional dimensions of the LHFQ and SF-36 were significantly correlated (coefficients from .46 to .70 for physical dimension and from .31 to .65 for emotional dimension). However, contrary to expectations, the divergent validity was not totally confirmed as there was no difference in the magnitude of the correlations between the LHFQ emotional and physical dimensions and the SF-36 role physical, social functioning and role emotional. Thus, the results suggest that LHFQ seems to be a valid tool to measure HRQL in the elderly, but new studies remain necessary to gain a better understanding of its discriminative validity for more advanced NYHA functional classes and for its divergent validity.     

农村空巢老人SF-36量表应用信度及效度评价

目的评价简明健康调查量表(SF-36)应用于农村空巢老人生存质量测量时的信度和效度。方法采用中文版SF-36量表,对江苏省徐州市分层整群随机抽取218名农村空巢老人进行面访调查,评价该量表的信度和效度。结果 SF-36量表的分半系数为0.84,生理职能(RP)、生理功能(PF)、躯体疼痛(BP)、总体健康(GH)、精力(VT)、社会功能(SF)、情感职能(RE)和精神健康(MH)8个维度Cronbach’sα系数为0.79、0.88、0.86、0.81、0.77、0.76、0.88、0.77,量表具有良好的分半信度和内部一致性信度;效度分析表明,集合效度和区分效度试验成功率分别为97.14%和97.96%,因子分析(RMSEA=0.12,CFI=0.91),PF、VT、RE、MH 4个维度在因子负荷上与理论模型完全一致;量表反应度评价表明,除RP、BP、SF 3个维度天花板效应分别为42.63%、48.79%、26.45%外,其他维度地板效应和天花板效应均不显著。结论 SF-36量表适用于农村空巢老人生存质量评价,但尚需根据实际情况对部分条目进行完善。     

The MOS SF-36 health survey questionnaire in severe chronic airflow limitation: Comparison with the Nottingham health profile

This study documents the cross-sectional, health-related quality of life (HRQOL) measures obtained at baseline for patients with severe chronic airways limitation (CAL) being assessed for home oxygen therapy (HOT) at the Flinders Medical Centre, Adelaide, South Australia. Two generic quality of life instruments, the Nottingham Health Profile (NHP) and the Medical Outcomes Study (MOS) short form 36-item questionnaire (SF-36), were administered by interview to the same patients to permit comparisons to be made between the two instruments. SF-36 mean scores were also compared with scores obtained in separate studies of a South Australian elderly general population and of groups of Australian subjects with various medical and psychiatric conditions. NHP mean scores were compared with scores from an elderly group of Adelaide residents from a household survey. HRQOL measures were obtained for 60 patients, 32 males and 28 females. At assessment for HOT, patients with severe CAL were experiencing severe impairment in their quality of life in comparison to age-matched South Australian norms, with physical disability the major limitation. There were several significant correlations between the domains of the SF-36 and the NHP which were predominantly gender-specific. Only small decrements in mental health were found with the SF-36 questionnaire. The SF-36 and the NHP appear to provide discrepant information for severely disabled CAL patients for the subjective domains of emotional and mental health.     

Cultural adaptation and application of the IBS–QOL in China: a disease-specific quality-of-life questionnaire

Background Irritable bowel syndrome (IBS) is a chronic and episodic illness characterized by altered bowel habits and associated abdominal pain. At present, IBS is one of the most common functional gastrointestinal and motility disorders affecting countries around the world. Surveys have found that patients with IBS have a significantly lower health-related quality of life. Objectives The aim of this study was to translate and examine the validity of the Irritable Bowel Syndrome–Quality of Life questionnaire (IBS–QOL) in patients suffering from IBS in China. Methods A structured procedure was used for the translation and cultural adaptation of the original English IBS–QOL into Chinese. The questionnaire was administered to 73 clinical patients with IBS and␣70 healthy individuals. Psychometric testing for reliability, validity and responsiveness followed standardized procedures. Test–retest reliability (10–20 hours) was assessed using the clinical patients. Follow-up (4 weeks) was collected for 61 clinical patients. All enrolled patients also completed the Short Form-36 Health Survey (SF-36) at the baseline visit. Responsiveness to treatment (Venlafaxine and traditional Chinese herbal medicine) was assessed by one-way ANOVA methods. Results The average length of time required to complete the questionnaire was short (5.63 min for IBS patients and 5.54 min for healthy subjects by self-administration). Internal consistency (Cronbach’s alpha) values ranged from 0.722 to 0.914 for the Chinese IBS–QOL subscales and test–retest reliability coefficients were higher than 0.920 on all subscales. The convergent and discriminate validity results comparing the Chinese translation of the IBS–QOL overall score and the SF-36 subscales confirmed our predicted hypotheses. The Chinese IBS–QOL scores are more highly correlated with social functioning, vitality and general health (SF-36) and show weaker associations with physical functioning, role physical, mental health, and bodily pain (SF-36). The Chinese translation of the IBS–QOL was responsive to treatment. Conclusion In general, the Chinese translation of the IBS–QOL, after cultural adaptation and revision, possesses good reliability, validity and responsiveness. It is a reliable and valid instrument to assess the quality of life in Chinese patients suffering from IBS and is an appropriate measure to use in further clinical trials or for related research projects in China.     

Quality of life at the initiation of maintenance dialysis treatment – a comparison between the SF-36 and the KDQ questionnaires

Objective: To evaluate the construct validity of the Medical Outcomes Study Questionnaire 36-Item Short Form Health Survey (SF-36) and to assess the quality of life of patients with end-stage renal disease (ESRD) at the initiation of maintenance dialysis treatment. Methods: Cross-sectional study. Setting: Eight ambulatory dialysis units in São Paulo city, Brazil. Study participants: Eighty ESRD patients at the initiation of chronic dialysis program and consecutively accepted for treatment in selected units in 1998. Main outcome measures: Quality of life as measured by the dimensions of the SF-36 questionnaire. The `Kidney Disease Questionnaire' was used in a subgroup of patients to evaluate the validity of the SF-36. Results: Median (range) scores of the SF-36 dimensions (ranging from 0 to 100, higher scores representing better quality of life) were: Physical Function 70 (0–100), Role Limitations due to Physical Problems 25 (0–100), Bodily Pain 62 (0–100), General Health 57 (5–100), Vitality 55 (10–100), Social Function 63 (0–100), Role Limitations due to Emotional Problems 34 (0–100) and Mental Health 68 (0–100). SF-36 dimensions correlated significantly with those of the `Kidney Disease Questionnaire' (correlation coefficients ranging from 0.23 to 0.68). Conclusions: The SF-36 was shown to have construct validity when used in patients with ESRD in Brazil. The quality of life of ESRD patients is impaired at the initiation of dialysis treatment and this was clearly evidenced in the Role Limitations due to Physical Function and Emotional Function items. Greater attention should be given to interventions that could improve the quality of life parameters at the initiation of dialysis treatment.     

Comparing discriminative validity between a disease-specific and a general health scale in patients with moderate asthma

Health-related quality of life scales such as the Asthma Quality of Life Questionnaire and the Medical Outcomes Study Short-form General Health Survey SF-36 have become important measures of health status in clinical asthma trials. The discriminative properties of these scales, however, have not been extensively evaluated and compared. The purposes of this study were to assess and compare scale and discriminative properties of the Asthma Quality of Life Questionnaire (AQLQ) and the SF-36 in a group of patients with moderate asthma using a patient-rated global measure of disease activity as the criterion variable. Patients were interviewed in-person with a series of questionnaires including the AQLQ and the SF-36, and were also asked the global question "How active is your asthma now?" with possible responses of "extremely," "very," "moderately," "mildly" or "not active." Discriminative properties were determined using receiver operating characteristic (ROC) curves with responses to the global question as the criterion variable and mean domain scale scores as the independent variables. Relative validities for the AQLQ and SF-36 domains were also compared. A total of 230 patients, mean age of 41 years, were enrolled. Scores were lower and ranges were narrower for the AQLQ compared to the SF-36. In general, the AQLQ and the SF-36 were highly correlated, with r = 0.69 for the AQLQ overall score and the SF-36 Physical Component Summary (PCS) score. According to ROC analyses, both scales had excellent discriminative properties; however the area under the ROC curve was higher for the AQLQ overall score (0.81) than for the PCS (0.75). When ranked according to ROC area, the symptoms domain (0.83) had the greatest area under the ROC curve, followed by the emotional (0.76) and activities (0.76) domains of the AQLQ. However, in some cases, the area under the curve was less for an AQLQ domain (for example, 0.71 for the environmental domain) than for SF-36 domains (for example, 0.75 for the role physical, and 0.75 for the social domain). Similarly, the AQLQ overall had a higher relative validity (5.2) compared to the PCS (2.2), and the symptoms domain of the AQLQ had the highest relative validity (6.0). Thus, both the Asthma Quality of Life Questionnaire and the SF-36 were able to characterize patients with moderate asthma in our cross-sectional study. In addition, both scales had strong discriminative properties when assessed with a global patient rating of current disease activity.     

Psychometric properties of a specific quality of life questionnaire in angina pectoris patients

This paper describes the psychometric properties of the French version of the APQLQ (Angina Pectoris Quality of Life Questionnaire), that is to say, scaling assumptions, reliability and validity. This disease-specific Swedish questionnaire provides a global score as well as four subscores measuring physical activities, somatic symptoms, emotional distress, and life satisfaction. The French version was produced according to the forward-backward translation methodology. In a cross-sectional study, 183 coronary patients filled out the APQLQ and the MOS (Medical Outcomes Study) SF-36; 170 sent it back; the rate of missing data was low (1.3%). The factorial structure and the high level of inter-scale correlations (> 0.60) suggested that the APQLQ measured one global concept rather than separate domains. The multitrait analysis identified one problematic item correlated strongly with all domains. The internal consistency was good ( Cronbach > 0.70). The correlations with the SF-36 scales were consistent with what was expected. The distribution of the scores of the APQLQ according to the clinical severity of Angina Pectoris (AP) was as hypothesized: the more severe the AP, the more impaired the Quality of Life. The score significantly discriminated between symptomatic (n=110) and asymptomatic patients (n=60) except for the emotional distress scale (p=0.14). We recommend to analyze the French APQLQ as an index rather than as a profile. Its reliability, concurrent and clinical validity allowed its use in clinical trials.