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室性心律失常患者的心率变异性分析 总被引:18,自引:2,他引:16
为研究自主神经系统活动在室性心律失常发生中的作用,分析35例正常人(对照组)、34例无器质性心脏病室性心律失常者(无心脏病组)及35例器质性心脏病室性心律失常者(心脏病组)的心率变异性。结果显示(1)与对照组比较,无心脏病组SDNN、PNN50、RMSSD、HRVTI显著降低(P〈0.05~0.01),SDANN、SDNNIndex无显著差异(P〉0.05);而心脏病组各项指标均非常显著降低(P〈 相似文献
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目的:探讨自主神经系统活动在室性心律失常(VR)发生中的作用。方法:分析38例正常人(A组),46例无器质性心脏病VR(B组)及45例器质性心脏病VR(C组)的心率变异性(HRV)。结果:(1)与A组比较,B组SDNN,PNN50,RMSSD,HRVTI显降低(P<0.05-0.01),SDANN,SDNNindex无显差异(P>0.05);C组各项指标均显降低(P<0.01),(2)C组各项指标均比B组显降低(P<0.05-0.01)。提示:迷走神经张力降低在VR的发生中起重要作用,HRV减低可作为高危性VR的独立预测指标。 相似文献
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目的探讨冠心病与非冠心病室性心律失常患者心率变异性的差异。方法选自2011年1月至2013年10月于我院行24h动态心电图检查的患者560例。按照患者24h动态心电图室性心律失常的类型、数目、形态及有无冠心病分为5组:健康对照组143例;简单室早非冠心病组100例;简单室早冠心病组102例;复杂室早非冠心病组106例;复杂室早冠心病组109例;各组年龄构成比、男女比例无显著差异。所有患者均进行24h心率变异性检测,并对检测结果进行分析。结果比较这五组患者的24h心率变异性时域分析指标,非冠心病室早组心率变异性时域分析指标增高;冠心病室早组心率变异性时域分析指标降低。室早冠心病组与非冠心病组24h心率变异性时域分析指标有显著差异。结论 24h心率变异性时域分析对于室早的危险分层、科学处理、合理治疗有重要意义,心率变异性时域分析是一项在室早诊疗过程中有价值的辅助检查。 相似文献
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毛袁心 《心电图杂志(电子版)》2020,(3):35-35
目的 分析冠心病合并室性心律失常的心率变异性.方法 选择34例冠心病病例,纳入A组,A1组为合并室性心律失常组,A2为无合并症组,B组为健康人群,以上病例均采用GE Mac V8 3导动态心电图检查.结果 将A组及B组SDNN、SDANN、RMSSD、PNN50进行对比分析,明显A组更低(P<0.05);将A1组及A2组以上数据进行比较,明显A1组更低(P<0.05).结论 冠心病合并室性心律失常实施24 h动态心电图检测,可明确了解患者心率变异性,有利于患者诊治. 相似文献
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冠心病患者心率变异性与室性心律失常的相关性 总被引:2,自引:0,他引:2
心率变异性 (HRV)是近年发展起来的无创性检查 ,定量分析、评价心脏自主神经系统功能 ,为了解 HRV变化与室性心律失常的关系 ,作者对冠心病患者 HRV与室外性心律失常进行分析探讨。1 对象和方法 根据 WHO诊断标准确诊冠心病患者 68例 ,按 2 4h动态心电图室性早搏进行 L own分级 ,L own分级≥ 级为高危室早组 ,3 1(男 2 5,女 6)例 ,年龄 45~ 75(61± 10 )岁 ;L own分级≤ 级为低危室早组 ,3 7(男 2 7,女 10 )例 ,年龄 47~ 78(64± 6)岁。采用美国 Brentwood-880 0型 3通道动态心电图分析系统 ,连续检测 2 4h心电信号 ,专人分析… 相似文献
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目的:探计索他洛尔对室性心律失常(VR)患心率变异性(HRV)的影响。方法:20例VR服用索他洛尔(80mg,每日2次)。2W,测定用工前后的24h的HRV的时域指标,并与30例正常人比较。结果:VR的HRV各指标均低于正常人,治疗后HRV各指标较治疗前增高,并与正常对照组比较无显性差异。结论:VR交感神经活性增强,副交感神经活性降低,HRV程度降低,索他洛尔可改善VR的HRV。 相似文献
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吸烟的室性心律失常患者心率变异性分析 总被引:1,自引:0,他引:1
目的 探讨吸烟的室性心律失常患者心律变异(HRV)的临床意义。方法应用24h动态心电图(DCG)对50例吸烟组、60例不吸烟组。进行心率变异性时域分析。结果与不吸烟组比较.吸烟组SDNN、rMSSD、PNN50明显降低。结论吸烟可致室性心律失常患者交感神经活性明显增强,副交感神经活性明显降低.心率变异程度减低,从而增加心电的不稳定性。 相似文献
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卡维地洛对慢性心力衰竭患者室性心律失常和心率变异性影响 总被引:1,自引:0,他引:1
目的 探讨卡维地洛对慢性心力衰竭患者室性心律失常和心率变异性的影响。方法 97例慢性心力衰竭患者按随机分配原则,分为治疗组49例和对照组48例,治疗组在常规治疗的基础上加用卡维地洛,初始剂量2.5mg,每Et两次,每2周增加一次剂量,直至20mg一次或最大耐受量为止。用动态心电图分析治疗前后心率、室性心律失常和心率变异性变化,并用超声心动图测定患者治疗前后的心功能。结果 治疗组用卡维地洛治疗6个月后,心率下降、室性心律失常减少、心率变异性参数改善(P〈0.01);心功能改善亦非常显著(P〈0.01)。结论 卡维地洛治疗慢性心力衰竭患者,可降低室性心律失常的发生,改善心率变异性和心功能。 相似文献
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为研究自主神经系统活动在无器质性心脏病室性心律失常发生中的作用,分析22例住院患者(心律失常组)和26例正常人(对照组)的心率变异性,结果显示心律失常组的时域指标平均NN间期、SDNN、lgNN_(50)、PNN_(50)均较对照组降低(832.33±92.41ms对905.86±121.98ms,P<0.05;125.96±37.02ms对163.28±25.2ms,3.73±0.51对4.13±0.23,9.65%±6.63%对16.82%±8.69%,P均<0.01)。提示迷走神经张力减低对进一步探讨无器质性心脏病室性心律失常的发生机制、指导临床治疗有一定价值。 相似文献
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为探讨充血性心力衰竭(CHF)患者自主神经张力变化与室性心律失常的关系,我们对CHF患者有或与持续性室性心动过速(NSVT),CHF患者与正常组各项心率变异(HRV)时域指标进行比较。结果:CHF组的HRV降低,其HRV各项指标与患者的LVEF不存在直线相关,死亡者的SDRR、SDANN明显低于存活者(P<0.001);CHF有NSVT者与无VT者HRV差异无显著性(P>0.05)。作者认为HRV低表示自主神经张力失衡,容易导致猝死。在预测CHF患者预后时,HRV优于LVEF和NSVT;HRV时域指标SDRR、SDANN敏感性优于PNN50。 相似文献
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Wavelet transform for analysis of heart rate variability preceding ventricular arrhythmias in patients with ischemic heart disease 总被引:2,自引:0,他引:2
Burri H Chevalier P Arzi M Rubel P Kirkorian G Touboul P 《International journal of cardiology》2006,109(1):101-107
INTRODUCTION: Studies evaluating changes in HRV preceding the onset of ventricular arrhythmias using conventional techniques have shown inconsistent results. Time-frequency analysis of HRV is traditionally performed using short-term Fourier transform (STFT). Wavelet transform (WT) may however be better suited for analyzing non-stationary signals such as heart rate recordings. METHODS AND RESULTS: We studied patients with a history of myocardial infarction implanted with a defibrillator with an extended memory. The RR intervals during the 51 min preceding ventricular events requiring electrical therapy were retrieved, and HRV studied by WT and STFT. 111 episodes of ventricular arrhythmia were retrieved from 41 patients (38 males, age 64 +/- 8 years). Heart rate increased significantly before arrhythmia. There was no significant variation in low frequency / high frequency components (LF/HF) observed for the group as a whole, probably due to a great degree of heterogeneity amongst individuals. A subset of 30 patients also had heart rate recordings performed during normal ICD follow-up. WT did not show any difference in HRV before arrhythmia onset and during control conditions. CONCLUSION: Variations in HRV before onset of ventricular arrhythmias were not apparent in this large dataset, despite use of optimal tools for studying time-frequency analysis. 相似文献
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《The American journal of cardiology》1993,72(4):A67-A71
Reduced vagal activity has been demonstrated to be associated with an increased risk of sudden death. Assessing the heart rate variability as a measure of the autonomic control of the heart has been established as a useful tool for the risk stratification of patients after myocardial infarction. In the current study, heart rate variability assessed by time- and frequency-domain measures was determined from Holter recordings before and during treatment with sotalol in 28 patients wtth chronic ventricular arrhythmias. The heart rate variability at baseline was independent of the presence or absence of spontaneous arrhythmias and of left ventricular function. Therapy with sotalol produced a significant improvement over control values in indices of parasympathetic tone (root mean square of the difference in successive RR intervals, proportion of adjacent RR intervals different by > 50 msec, high-frequency power spectrum). This improvement was not related to drug-induced changes in the mean heart rate or the suppression of ventricular ectopic activity. These effects on heart rate variability may contribute significantly to the overall efficacy profile of sotalol. 相似文献
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Riahi S Schmidt EB Christensen JH Heath F Pedersen AK Nielsen JC Mølgaard H Toft E 《Cardiology》2005,104(4):210-214
The aim of this study was to evaluate whether the incidence of ventricular arrhythmias and heart rate variability were influenced by statin treatment and lipid levels in patients treated with an implantable cardioverter defibrillator (ICD). Heart rate variability measurements were performed in 86 patients with coronary heart disease and an ICD implant. The number of events with ventricular fibrillation and ventricular tachycardia were recorded during a 12-month period. This study lends little support for an antiarrhythmic effect of statins or any relation between plasma lipids and lipoproteins and malignant ventricular arrhythmias in patients with an ICD. 相似文献
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目的:研究老老年高血压患者左心室肥厚(LVH)与心律失常及心率变异性(HRV)的关系。方法:纳入2012年10月至2014年7月于中国中医科学院广安门医院心内科住院的303例老老年高血压病患者,根据是否合并左心室肥厚分为2组,检测24小时动态心电图心率变异性时域分析及超声心动图,观察2组之间相关指标的差异。结果:老老年高血压合并LVH组较不合并LVH组房性、室性心律失常检出率增高,差异具有统计学意义(P<0.05),二组PNN50、RMSSD、SDNN、SDANN差异无统计学意义。结论:老老年高血压合并LVH心律失常的发生率明显增高,而二者心率变异性无明显差异。 相似文献
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《Journal of the American College of Cardiology》1995,25(2):437-443
Objectives. The aim of this study was to determine the relation between autonomic control of heart rate and the spontaneous occurrence and inducibility of ventricular arrhythmias in patients with coronary artery disease.Background. Low heart rate variability increases the risk of arrhythmic events. It is not known whether impaired autonomic heart rate control reflects alterations in functional factors that contribute to the initiation of spontaneous arrhythmias or whether it is the consequence of an anatomic substrate for reentrant tachyarrhythmias.Methods. Fifty-four patients with coronary artery disease with a history of sustained ventricular tachycardia (n = 25) or cardiac arrest (n = 29) were studied by 24-h ambulatory electrocardiographic recording and by programmed electrical stimulation. Heart rate variability was compared among the patients with and without spontaneous ventricular arrhythmias and with and without inducibility of sustained ventricular tachyarrhythmias.Results. Eight patients had a total of 21 episodes of sustained ventricular tachycardia on Holter recordings. Standard deviation of RR intervals and low frequency and very low frequency components of heart rate variability were significantly blunted in patients with sustained ventricular tachycardias compared with those without repetitive ventricular ectopic activity (p < 0.05, p < 0.01 and p < 0.05, respectively). However, no significant alterations were observed in heart rate variability before the onset of 21 episodes of sustained ventricular tachycardia. Heart rate variability did not differ between the patients with or without nonsustained episodes of ventricular tachycardia. In patients with frequent ventricular ectopic activity, low frequency and very low frequency power components were significantly blunted compared with those with infrequent ventricular ectopic activity (p < 0.01 and p < 0.001, respectively). Heart rate variability did not differ significantly between the patients with and without inducible sustained ventricular tachyarrhythmias.Conclusions. Impaired very low and low frequency oscillation of heart rate reflects susceptibility to the spontaneous occurrence of ventricular arrhythmias but may not reflect the instantaneous triggers for life-threatening arrhythmias or a specific marker of the arrhythmic substrate for ventricular tachyarrhythmias. 相似文献
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目的分析特发性右室流出道室性早搏患者的临床特点和24h动态心电图结果,探讨该类室早与心率变异性(HRV)的关系及临床意义。方法 43例特发性右室流出道室性早搏患者,根据24h动态心电图室早数目分为3组:A组(<1000个),B组(1000~10000个),C组(>10000个),观察3组临床资料,比较各组间HRV(SDNN、SDANN和rMSSD)的差异,分析HRV与室早数量的相关性。结果特发性右室流出道室性早搏多见于中青年女性,其症状与室早数目有关;各组间SDNN和SDANN差异无显著性(p>0.05),而rMMSD有统计学差异(p<0.05),且rMSSD与室早数量存在负相关(r=-0.567,p=0.014)。结论特发性右室流出道室性早搏的发生与自主神经调节失衡有关,迷走神经张力减弱有重要的作用。 相似文献