Chondrosarcoma arising in the nasal septum

A case is presented of a chondrosarcoma arising in the nasal septum and extending into the maxillary sinuses. This tumour is unusual in the head and neck and rarely arises in the nasal septum. Diagnostic difficulties are discussed. The treatment was radical surgery with removal of a major portion of the upper jaw, necessitating reconstruction with a maxillo-facial prothesis.     

Chondrosarcoma of the nasal septum: A case report

Chondrosarcoma make up only 10–20% of malignant primary bone tumors, with 5–10% located in the head and neck (Downey TJ, Clark SK, Moore DW. Chondrosarcoma of the nasal septum. Otolaryngol Head Neck Surg 2001;125:98–100), and nasal septal chondrosarcoma is extremely rare. Surgical excision is the only curative treatment and radiation and chemotherapy have a limited role for palliation. We used a navigation system in endoscopic surgery without complications for a case of chondrosarcoma of the nasal septum by means of a midfacial degloving approach at primary operation and an external incision approach at salvage operation for local recurrence. To our knowledge, this is the first report of the use of such a system for this surgical approach along with a salvage operation. We discuss the clinical presentation, diagnosis, and treatment of this case as well as present a review of the literature.     

Chondrosarcoma of the nasal septum

Chondrosarcoma of the head and neck region are relatively uncommon, arising rarely in the naval septum. The reported cases of nasal septal chondrosarcomas are extensive lesions with involvement of paranasal sinuses, orbit or skull base at the lime of diagnosis. Those limited to the nasal cavity is extremely rare and to date there has been one case report in English language literature. We present a case of chondrosarcoma of the nasal septum with involvement of the nasal cavity alone and no evidence of bony erosion. Initial multiple biopsies showed mature chondromatous areas with no atypia. The patient had wide excision of the tumour. The final biopsy of the excised specimen revealed foci of well-differentiated chondrosarcoma. Wide surgical excision with adequate margins should be considered as the treatment of choice in lesion of nasal septum even if initial biopsies are negative for malignancy. Hence this case report.     

Chondrosarcoma of nasal septum

Chondrosarcomas are the tumours of the Osteogenic series. This tumour may occur in any bone, but with a predilection for flat bones and ribs. Chondrosarcomas of the nasal cavity and paranasal sinuses are rare tumours. Still rarer is the chondrosarcoma of nasal septum. Rarity of this neoplasm warrants its presentation.     

Chondrosarcoma of the nasal septum

European Archives of Oto-Rhino-Laryngology - Chondrosarcomas are non-epithelial malignant, slow growing tumors that usually involve pelvis, ribs, and long bones of extremities, scapula and sternum....     

Chondrosarcoma of the nasal septum

Chondrosarcoma of the nasal septum is a rather uncommon tumour. Therefore, only limited numbers of cases have been described in the literature. This paper reveals one more case observed at the ORL department of Dicle University. In the present case, by using a transnasal and transpalatal approach, total resection of the tumour was performed in conjunction with postoperative radiotherapy.     

Chondrosarcoma of the nasal septum

INTRODUCTION: A chondrosarcoma is rarely located in the nasal septum with only fifty cases reported in the literature. CASE REPORT: We report a new case of a seventy years old woman presenting with a large facial midline mass extending to the nasal cavity, having evolved for six months. Subsequent computed tomography revealed a mass destroying the nasal septum and extending to the endocrane. Intranasal biopsy revealed a chondrosarcoma. The extended work up revealed pulmonary metastasis. The course was not favourable and the patient died after one year. DISCUSSION: The bones of the pelvis and of the lower extremities are the most common localizations for chondrosarcoma. It is rarely located in the nasal septum. Histological analysis is required for the diagnosis. It is characterized clinically by local aggressiveness, frequent metastatic evolution, and poor prognosis. Surgical resection is reserved to operable cases. Chemotherapy and radiotherapy used as adjuvant treatment and palliation are not effective.     

Chondrosarcoma of the nasal septum: A report of an uncommon lesion

Chondrosarcoma of the nasal septum is an uncommon lesion. Review of the English literature reveals only 14 cases. This paper reports an additional case observed in a Japanese series of seven cases. The clinical features are reviewed, and a most effective treatment with minimum side effects is organized by an interdisciplinary group of specialists in surgery, radiotherapy and regional chemotherapy.     

鼻中隔骨纤维结构不良一例

患者男，15岁，于7个月前反复出现双侧鼻腔间歇性鼻塞，偶有涕中带血，无头痛、无鼻腔脓性分泌物及嗅觉减退，有鼻腔局部胀痛，曾多次在当地医院就诊，均诊断为慢性鼻炎、腺样体炎，经药物干预无效。2个月前患者双侧鼻塞呈持续性，并进行性加重，于2006年10月18日来我院就诊，门诊拟诊为：①鼻中隔良性占位性病变；②蝶窦囊肿；③鼻中隔纤维血管瘤。患者既往体健，家属否认有鼻部外伤史。     

Pleomorphic adenoma of the nasal septum: a case report

Pleomorphic adenomas arise most commonly in the major salivary glands; the minor salivary glands are affected in only 8% of the cases. Intranasal pleomorphic adenoma being extremely rare originates most commonly from the nasal septum. We present a case of a 55-year-old man who presented with complaints of right-sided nasal obstruction and occasional nasal bleed for the last 6 months. Examination showed a mucosa-covered, fleshy 2 x 2 x 1.5 cm mass in the right nasal cavity. Computed tomogram showed right-sided polypoidal mass with attachment to the cartilaginous nasal septum without any erosion of the surrounding structures. The clinical presentation, gross and microscopic appearance, and treatment of intranasal pleomorphic adenoma is briefly discussed.     

Choanal polyp originating from the nasal septum: a case report

Almost all nasal polyps originate from the mucosa of the lateral walls of the nasal cavity or from the paranasal sinuses. A choanal polyp is the intranasal portion of a cyst that has arisen from the wall of the maxillary sinus near the ostium. Medially based polyps, such as those that arise from the nasal septum, are rare. The literature cites a wide range of incidence rates for polyps originating from this structure, but choanal extension of this type of polyp is extremely unusual. This report describes a polyp that arose from the superior aspect of the posterior nasal septum and extended through the choana into the nasopharynx. The histology of this choanal lesion was typical of nasal polyps, but the site of origin is rare. The ethiopathogenesis of nasal polyps with its common location remains controversial so it is difficult to speculate what mechanism triggered the development of this lesion on the nasal septum. Some form of local inflammation may have induced choanal polyp formation at this atypical site.     

A case of extramedullary plasmacytoma arising from the nasal septum

A rare case of extramedullary plasmacytoma arising from the nasal septum with localized amyloid deposition is reported. A 75-year-old woman presented with a history of post-nasal discharge and nasal obstruction for several months. Endonasal endoscopic observation revealed the presence of a mass arising from her nasal septum with an extension to the nasopharynx. No cervical lymph nodes were palpable. The biopsy specimen was diagnosed as a plasmacytoma (IgG, lambda-light chain type). Both serum myeloma-protein and urine Bence-Jones protein were negative. Bone marrow biopsy, a chest radiograph, total body skeletal survey and 67Ga- and 99mTc-scintigrams showed no other systemic lesions. These findings confirmed the diagnosis of extramedullary plasmacytoma in the nasal septum. The patient received irradiation of 40 Gy without clinically detectable reduction of tumour size. The patient eventually underwent complete resection of the tumour by KTP/532 laser under endonasal endoscopic control. Pathologically, the tumour mass was composed mainly of amyloid deposition with a marked reduction of tumour cells. This indicated the radiosensitiveness of tumour cells, which was clinically masked by the increased amyloid deposition. The clinical presentation, pathological features and surgical procedures are described with a review of the literature.     

Chondrosarcoma of the paranasal sinuses and nasal septum

A case of chondrosarcoma of the left antro-ethmoid region and nasal septum is presented as a second primary malignant tumour in a patient who had undergone a previous excision of a rodent ulcer in the cheek. X-ray studies and multiple biopsies of the nasal cavity were undertaken to determine as accurately as possible the extent of the tumour. The tumour was excised via a lateral rhinotomy. Chondrosarcoma of the maxillofacial region is a rare tumour. The treatment of choice is by surgical excision. Radiotherapy may be considered in non-resectable or recurrent tumours.     

鼻腔鼻中隔黏液性软骨肉瘤一例

原发的脊柱外黏液性软骨肉瘤是少见的肿瘤,发牛在鼻腔和鼻中隔则更为少见.2006年和2007年国外各有1例报告[1-2].作者曾遇1例,经手术和放疗后已无瘤存活3年,报告如下.     

鼻中隔神经纤维瘤一例报告

正1病历资料患者女,22岁,因"左侧进行性鼻塞5年余"入院,查体:鼻中隔略右偏,无血肿,鼻中隔左侧有一1.5 cm×1 cm大肿物,肿物表面光滑,未见明显色素沉着或红肿破溃,触痛不明显,左侧中鼻道及嗅裂无法窥及;右侧鼻腔黏膜略有充血,无撕裂。患者全身分布大小不等的牛奶咖啡斑及孤立神经纤维瘤,瘤体质略韧,呈囊实性。实验室检查:未见明显手术禁