军医大学科技人员心理卫生状况及相关因素研究

目的 研究军医大学科技人员的心理卫生状况及其影响因素。方法 采用症状自评量表，对某军医大学320名科技人员进行测试，与SCL－90中国常模、军人常模比较各因子分的差异，并按性别、年龄专业、学历和职称等分组，进行组间比较。结果 ①军医大学科技人员在躯体化、人际关系、焦虑、敌对性、恐怖和偏执六个因子的得分和总均分显著低于全国常模组（P＜0．05）；各因子分、阳性项目数和总均分非常显著地低于军人常模（P＜0．01）；②军医大学科技人员心理卫生水平在年龄上除躯体化因子分呈现20岁组和40岁组（P＜0．01）、30岁组和40岁组（P＜0．05）有显著差异，职称上躯体化因子分呈现初级组和高级组有显著差异（P＜0．01）外，未表现出明显的年龄、性别、专业、学历和职称特征。结论 军医大学科技人员心理卫生水平总体较好；军医大学科技人员产生心理问题的主要原因可能是工作压力大、科技竞争激烈、家庭负担重等。     

军医大学科技人员心理卫生状况及相关因素研究

目的研究军医大学科技人员的心理卫生状况及其影响因素.方法采用症状自评量表,对某军医大学320名科技人员进行测试,与SCL-90中国常模、军人常模比较各因子分的差异,并按性别、年龄、专业、学历和职称等分组,进行组间比较.结果①军医大学科技人员在躯体化、人际关系、焦虑、敌对性、恐怖和偏执六个因子的得分和总均分显著低于全国常模组(P<0.05);各因子分、阳性项目数和总均分非常显著地低于军人常模(P<0.01);③军医大学科技人员心理卫生水平在年龄上除躯体化因子分呈现20岁组和40岁组(P<0.01)、30岁组和40岁组(P<0.05)有显著差异,职称上躯体化因子分呈现初级组和高级组有显著差异(P<0.01)外,未表现出明显的年龄、性别、专业、学历和职称特征.结论军医大学科技人员心理卫生水平总体较好;军医大学科技人员产生心理问题的主要原因可能是工作压力大、科技竞争激烈、家庭负担重等.     

军医大学科技人员心理卫生状况及相关因素研究

目的研究军医大学科技人员的心理卫生状况及其影响因素.方法采用症状自评量表,对某军医大学320名科技人员进行测试,与SCL-90中国常模、军人常模比较各因子分的差异,并按性别、年龄、专业、学历和职称等分组,进行组间比较.结果①军医大学科技人员在躯体化、人际关系、焦虑、敌对性、恐怖和偏执六个因子的得分和总均分显著低于全国常模组(P<0.05);各因子分、阳性项目数和总均分非常显著地低于军人常模(P<0.01);③军医大学科技人员心理卫生水平在年龄上除躯体化因子分呈现20岁组和40岁组(P<0.01)、30岁组和40岁组(P<0.05)有显著差异,职称上躯体化因子分呈现初级组和高级组有显著差异(P<0.01)外,未表现出明显的年龄、性别、专业、学历和职称特征.结论军医大学科技人员心理卫生水平总体较好;军医大学科技人员产生心理问题的主要原因可能是工作压力大、科技竞争激烈、家庭负担重等.     

军事演习中海军某部军人心理健康状况评定

目的了解军事演习中海军不同类别军人的心理健康状况,为做好参演军人的心理服务工作提供参考依据。方法采用症状自评量表（symptom checklist,SCL-90）对军事演习中112名海军官兵进行测试。结果①被试SCL-90得分,除人际敏感因子外,其他各因子分和阳性项目数显著高于国内青年常模（P〈0．05或P〈0．01）,躯体化和抑郁因子显著高于军人常模（P〈0．05）;②农村籍组2个因子（焦虑、精神病性）高于城市组（P〈0．05）;有军演经历组4个因子（强迫、抑郁、焦虑、精神病性）得分和阳性项目数显著高于无军演经历组（P〈0．05或P〈0．01）;士兵组3个因子（躯体化、偏执、精神病性）得分显著高于军官组（P〈0．05或P〈0．01）;③演习中不同兵种军人的3个因子（抑郁、恐怖、精神病性）得分存在显著差异。进一步两两比较结果显示,潜艇部队的5个因子（人际敏感、抑郁、恐怖、精神病性、附加因子）分及阳性项目数、总均分显著高于水面舰艇部队（P〈0．05或P〈0．01）,且恐怖因子分显著高于陆战旅（P〈0．05）。结论军事演习条件下海军军人的心理健康水平低于平时,并低于一般人群;兵源户籍、参演经历、人员类别、兵种不同的参演军人心理健康水平有差异。     

重庆市某地区卫生系统工作人员心理卫生状况分析

目的：调查重庆市某地区卫生系统工作人员的心理卫生状况。方法以重庆市某地区卫生系统773名工作人员为研究对象,应用症状自评量表（SCL-90）调查,以 SCL-90总分大于160分为心理症状阳性,并在躯体化、强迫、人际关系、抑郁、焦虑、敌对性、恐怖、偏执、精神病性9项因子及总均分等方面进行统计分析。结果773名卫生系统工作人员心理症状阳性率为17．46％（135／773）,其中临床护士为23．20％（58／250）,临床医生为15．63％（50／320）,非临床工作人员为13．30％（27／203）。与中国人常模比较,该地区卫生系统工作人员在躯体化症状及强迫症状方面得分明显偏高（P ＜0．05）,而在人际关系和偏执方面得分明显偏低（P ＜0．01）;区级卫生单位工作人员在偏执方面得分高于卫生院工作人员（P ＜0．05）,而在其他8项因子及总均分方面明显高于卫生院工作人员（P ＜0．01）;临床护士在强迫、抑郁、焦虑、敌对性及总均分方面明显高于临床医生（P ＜0．01）,而在躯体化、人际关系、恐怖、偏执及精神病性等方面二者差异无统计学意义（P ＞0．05）;临床护士在总均分及各项因子得分均高于非临床工作人员（P ＜0．05）。结论该地区卫生系统工作人员多项因子得分与中国常模比较有明显差异,临床工作人员心理卫生状况较非临床工作人员差,尤其临床护士的心理卫生状况更差。     

驻西南某部战士心理健康调查

目的了解驻西南某部战士近期心理卫生状况。方法（1）对驻西南某部战士进行症状自评量表（SCL-90）测试，将结果与中国18—29岁常模和军男组常模进行比较；（2）将战士按军龄分为5组，比较各组战士间心理健康状况：（3）将新兵组和陆军新兵常模，一级士官组和军男组常模比较。结果（1）战士除躯体化外，其余所有因子均低于军男组常模（P〈0．01）；与全国18—29岁常模比较，躯体化、焦虑、精神病性3项因子偏高（P〈0．05），人际关系敏感、抑郁、恐怖、偏执4项因子偏低（P〈0．05）。（2）各组战士间心理健康存在差别，其中新兵健康水平最高，一级士官最低。（3）新兵组躯体化、强迫症状、敌对和恐怖因子与陆军新兵常模无明显差异．余因子均显著低于陆军新兵常模组（P〈0．05）。（4）与军男组常模比较，一级士官组躯体化偏高（P〈0.01）．人际关系敏感、抑郁和偏执偏低（P〈0．01）。结论驻西南某部战士心理健康状况较好，但一级士官心理健康状况仍不理想，需引起部队心理卫生工作者的重视。     

农村丧偶女性心理卫生初探(附43例SCL-90评定结果)

研究目的探讨农村丧偶女性心理卫生问题。研究背景丧偶是人生最严重的生活事件之一，特别对女性心理活动影响极大。我们通过量表评定分析农村这一人群的心理卫生存在的问题。方法以43例丧偶女性为研究对象，采用症状自评量表SCL－90进行评定，其结果与中国女性常模作对照研究。结果丧偶女性SCL－90阳性症状均分为2.63±0.41,阳性项目数为41.36±25.69,明显高于正常女性（P＜0.01），各因子分均高于女性常模，并且差异有显著意义（P＜0．01），分数较高的因子分为躯体化、强迫症状、人际关系敏感和抑郁。未改嫁组躯体化因子分明显高于改嫁组（P＜0.01），改嫁组敌对性和偏执二因子分数高于未改嫁组（P＜0.05）。结论丧偶者比较突出的心理卫生问题为：躯体化、强迫症状、人际关系敏感和抑郁4个方面。改嫁组在敌对性和偏执两方面的问题比未改嫁组明显。     

感染腺病毒新兵的心理状况及护理干预措施

目的：探讨腺病毒感染流行时新兵住院期间所出现的心理状况,并探讨采用护理干预措施的效果。方法采用症状自评量表SCL-90,对感染腺病毒新兵进行心理状态的调查,同时采用护理干预措施。结果（1）新兵SCL-90各因子分和阳性项目数显著高于国内常模（P＜0．05或＜0．01）,并有5个因子（躯体化、抑郁、焦虑、敌对、精神病性）显著高于军人常模（P＜0.05）。（2）入院时新兵SCL-90各因子分和阳性项目数显著高于出院时新兵SCL-90得分（P＜0．05或＜0．01）,并有4个因子（躯体化、抑郁、焦虑、精神病性）显著高于出院时新兵SCL-90得分（ P＜0．05）。经过采取相应的护理干预措施,出院时新兵SCL-90各因子分都有明显降低,差异有统计学意义（P＜0．01）。结论新兵在感染腺病毒后出现的一些心理问题与疾病的发生、发展及流行有关,采用护理干预措施后,症状得到改善。     

孕妇分娩前后心理症状的比较评定

目的 了解孕产妇的心理卫生状况，为孕妇提供心理卫生服务依据。方法 采用症状自评量表ＳＣＬ－９０，对孕产妇产前及产后１ｗｋ进行２次评定。结果 分娩前及分娩后孕产妇的抑郁、焦虑、恐怖因子均分显著高于国内常模（Ｐ〈０．０１（，分娩后孕产妇的躯体化因子均分也显著地常模（Ｐ〈０．０１），部宫产孕妇的躯体化、焦虑因子均分显著高于平产孕妇（Ｐ〈０．０１）。结论 抑郁、焦虑、恐怖及躯体化症状是孕妇常见的心理反应，     

健康教育对2型糖尿病病人心理卫生状况的影响

①目的研究健康教育对2型糖尿病病人心理卫生状况的影响。②方法采用症状自评量表（SCL-90）分析健康教育前后2型糖尿病病人的心理卫生状况。③结果2型糖尿病病人抑郁因子分、焦虑因子分、恐怖因子分、总分、躯体化因子分、人际关系敏感因子分与国内常模相比，差异具有显著性（t=2．45～9．57，P〈0．01、0．05）；健康教育后病人抑郁、焦虑、恐怖、躯体化、人际关系敏感等因子分与治疗前比较明显下降（t=1．98～3．56，P〈0．05）。④结论2型糖尿病病人存在心理卫生问题，健康教育能够明显改善其心理卫生状况。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.