异位妊娠腹腔镜术后持续性异位妊娠1例

患者,33岁,孕1产0,因“停经46 d,阴道不规则流血伴右下腹痛1 d”,于2006-01-14入院。患者停经38 d化验尿HCG弱阳性,血HCG 102 U/L,入院前1天复查血HCG327 U/L,B超示:宫后方积液(8 mm);右侧卵巢小囊肿(28 mm×32 mm)。入院第2天复查血HCG 2 168.32 U/L,B超示:宫后方积液稍增多(10 mm),妇查:宫颈举痛阳性,右附件增粗,压痛明显,后穹窿穿刺抽出不凝血2 m l。初步诊断:异位诊断,于次日行腹腔镜下探查术。术中见盆腹腔积血约300 m l,子宫大小形态正常,右输卵管壶腹增粗约2 cm×1 cm,紫蓝色,右卵巢增大,见一约3 cm×2 cm大小囊肿,术中诊断:右输卵管壶腹部妊娠;右卵巢囊肿。行腹腔镜下右输卵管妊娠开窗取胚术+右卵巢囊肿剥除术。术后病检报:送检血块组织中未见绒毛;(右)卵巢黄体囊肿。术后第3天复查HCG 1 157.44 U/L,患者无特殊不适,并于次日坚决要求出院。出院后一周复查HCG 2 354.42 U/L,考虑持续性异位妊娠,予米非司酮、甲氨蝶呤治疗,HCG曾一度降低后持续回升,最高达18 356.44 U/L,出...     

输卵管开窗取胚术治疗异位妊娠预后观察

目的观察输卵管开窗取胚术治疗异位妊娠的预后情况。方法选取自2015年1月至2017年1月武警特色医学中心收治的80例异位妊娠患者为研究对象,将患者随机分入A组和B组,每组各40例。A组患者接受输卵管切除术,B组患者接受输卵管开窗取胚术。比较两组患者围术期相关指标(术中出血量、手术时间、住院天数),近期预后指标(恶心呕吐、腹胀、皮下气肿等不良反应发生率和人绒毛膜促性腺激素下降至正常水平天数),以及5年宫内妊娠率和重复性异位妊娠率。结果 B组术中出血量为(51.56±16.58)ml,低于A组的(60.71±19.42)ml,差异有统计学意义(P<0.05)。A组手术时间为(1.16±0.23)h、住院天数为(5.34±1.36)d,B组手术时间为(1.13±0.22)h、住院天数为(5.25±1.42)d,两组比较,差异均无统计学意义(P>0.05)。A组术后恶心呕吐、腹胀、皮下气肿的发生率分别为10.0%(4/40)、7.5%(3/40)、5.0%(2/40),B组分别为12.5%(5/40)、5.0%(2/40)、2.5%(1/40),两组比较,差异均无统计学意义(P>0.05)。A组人绒毛膜促性腺激素下降至正常水平天数为(8.40±2.72)d,B组为(8.12±2.51)d,两组比较,差异无统计学意义(P>0.05)。B组5年宫内妊娠率为52.5%(21/40),明显高于A组的30.0%(12/40),两组比较,差异有统计学意义(P<0.05)。A组5年重复性异位妊娠率为10.0%(4/40),B组为15.0%(6/40),两组比较,差异无统计学意义(P>0.05)。结论输卵管开窗取胚术治疗异位妊娠临床效果显著,可减少患者术中出血量,提高术后宫内妊娠率。     

异位妊娠危险因素的临床调查

目的 探讨异位妊娠的相关危险因素和独立危险因素.方法 同顾性分析2005-2012年解放军总医院确诊的异位妊娠患者870例,并选取同期800例正常妊娠孕妇作为对照.对两组患者的相关因素进行配对比较,初步筛选可能导致异位妊娠的相关危险因素,采用logistic同归进一步确定异位妊娠的独立危险因素.结果 盆腔粘连、手术史、剖宫产史、妊娠次数、人工流产史、药物流产史、体外受精-胚胎移植(IVF-ET)史、宫内节育器(IUD)放置史在异位妊娠组和对照组差异均有统计学意义(P＜0.05),其中盆腔粘连、人工流产史、手术史、妊娠次数和IUD放置史是异位妊娠的独立危险因素,而盆腔粘连是异位妊娠的主要危险因素.结论 避免意外妊娠,减少人工流产的次数,防治妇女生殖道炎症,规范各种盆腔手术操作,可降低异位妊娠的发生率.     

甲氨蝶呤对输卵管妊娠腹腔镜保守手术治疗后持续性异位妊娠发生的影响

目的 分析甲氨蝶呤对输卵管妊娠腹腔镜保守手术治疗后持续性异位妊娠(PEP)发生的影响.方法 回顾性分析2005-2012年在解放军总医院行腹腔镜保守手术治疗的输卵管妊娠124例,将124例患者根据是否应用甲氨蝶呤(MTX)分为MTX组(n=92)和非MTX组(n=32).MTX组中40例于术中经输卵管系膜内注射MTX 25mg,52例于术后24h内经肌内注射MTX 50mg/m2.非MTX组术后给予期待疗法.分析预防性应用甲氨蝶呤以及给药方式对PEP发生的影响.结果 MTX组和非MTX组各7例发生PEP,两组差异有统计学意义(x2=4.825,P=0.028),MTX组的92例患者中,术中经输卵管系膜内注射MTX的40例患者中4例发生PEP,术后经肌内注射MTX的52例中3例发生PEP,两组差异无统计学意义(x2=0.576,P=0.448).结论 输卵管妊娠腹腔镜保守手术术中或术后预防性应用MTX可降低PEP的发生,但可能增加药物副作用.术中经输卯管系膜内注射与术后经肌内注射两种给药方式在改善PEP发生方面无差异.     

输卵管妊娠腹腔镜保守性手术156例临床对比分析

<正>随着显微技术的不断发展,腹腔镜输卵管妊娠的治疗已经成为异位妊娠的常规术式,但术后发生持续性异位妊娠(PEP)也日益增多,是导致再次治疗的主要原因[1],为探讨PEP的防治措施,本研究对我院收治的156例患者进行     

循证护理在腹腔镜下输卵管异位妊娠术后的应用

目的 腹腔镜下输卵管异位妊娠术后应用循证护理对预后的影响.方法 将腹腔镜下输卵管异位妊娠术后的患者随机分为两组,实验组接受循证护理,对照组给予常规护理.比较两组预后的情况.结果 实验组的护理评价分数高于对照组,对照组并发症发生率高于实验组,两者差异具有统计学意义(P＜0.05).结论 对腹腔镜下输卵管异位妊娠的患者应用循证护理可以改善预后、提高护理满意度.     

输卵管妊娠30例分析

我院1993年8月～1995年8月收治输卵管妊娠30例。1临床资料1．1一般情况年龄为21～35岁，初孕3例，有妊娠史27例（系第二次输卵管妊娠2例）。人工流产史15例，盆腔炎或附件炎史12例。军官山节育环（置环此例，既往和人院后透视或B超检查，均证实节育环位置正常。其中有的患者同时存在以上几种情况。1．2临床表现停经42～80d27例．轻度甲孕反应9例，在门诊首诊时误诊为正常只手而予入了流产术3例，阴道流血（少于正常月经量）20例，急腹症伴星厥28例。妇科检交：了宫均略增大，轻度压痛，患侧附件区有不规则包块、压痛、反跳痛、肌紧张、后穹…     

输卵管妊娠后慢性输卵管炎的造影分析

目的 研究慢性输卵管炎的造影表现,提高子宫输卵管造影术(HSG)对输卵管性不孕的诊断能力,并对输卵管妊娠患者再次备孕提供指导.方法 回顾性分析2018年1月至2019年8月在我院就诊的既往有输卵管妊娠史患者的资料,共计58例,115条输卵管,其中输卵管妊娠患病64条.在月经干净以后3～7 d内进行HSG检查,观察输卵管...     

Co-existent intrauterine and ectopic tubal pregnancy

A case of co-existent intrauterine and ectopic pregnancy is described in a patient from overseas. The difficulty in diagnosis and management is discussed, together with recent literature.     

输卵管妊娠保留输卵管手术治疗141例

目的:探讨保留输卵管手术在异位妊娠要求保留生育能力患者治疗中的重要性。方法:回顾性地详细介绍了141例保留输卵管手术的术式,术中术后及随访的治疗。结论:对比保留输卵管手术与辅助生育技术,阐明了保留输卵管手术的现实意义及重要性,进一步说明腹腔镜下保留输卵管手术的优越性及其将成为未来治疗的趋势,同时又指出在现有腹腔镜技术不能完成的手术时,如间质部妊娠,经腹手术保留输卵管仍是安全可靠的治疗方式。     

Magnetic resonance imaging in tubal and non-tubal ectopic pregnancy

Ectopic pregnancy is the leading cause of pregnancy-related death in the first trimester. Ectopic pregnancy is usually diagnosed by clinical, laboratory, and sonographic findings, with implantation most commonly located in the ampullary part of the fallopian tube. However, pregnancies that develop at unusual implantation sites, such as angular, interstitial, cornual, cervical, ovarian, cesarean scar, and abdominal cavity pregnancies, may rarely occur. Although ultrasound is considered the primary pregnancy-related imaging modality, it may not be able to illustrate the implantation site in certain types of pregnancy. Magnetic resonance imaging (MRI) has gained popularity as an imaging tool for evaluating pregnant patients, and it is used as a problem-solving tool in special circumstances, including ectopic pregnancy. MRI can confirm abnormal implantation site, and distinguish rupture from nonrupture cases before management. Other benefits include absence of ionizing radiation, superb soft tissue contrast, and sensitivity sufficient for identifying hemorrhage and its stages. This article summarizes imaging findings in tubal and non-tubal ectopic pregnancy with an emphasis on the roles and protocols of MRI, key MRI features, and differential diagnosis.     

输卵管插管介入治疗输卵管妊娠

目的探讨经输卵管途径治疗输卵管妊娠的可行性及临床疗效,降低插管难度,缩短手术时间。方法采用介入输卵管插管方法,插管前行宫颈外口注入阿托品0．5mg,插管成功后注入甲氨喋呤70mg治疗114例输卵管妊娠。结果113例获得成功,1例中转手术,未出现严重并发症。结论宫颈外口注入阿托品后输卵管插管治疗妊娠是简单、安全、微创、迅速有效的方法。     

Transvaginal ultrasound diagnosis of a live twin tubal ectopic pregnancy

A case of live twin tubal ectopic pregnancy diagnosed by transvaginal ultrasound is presented. This is a rare occurrence and we have calculated the incidence to be approximately 1:125,000 pregnancies. There have been more than 100 case reports of twin tubal ectopic pregnancy but only four previous reports where two foetal heart motions have been visualized. The introduction of high-resolution transvaginal ultrasound has resulted in earlier diagnosis of ectopic pregnancy and contributed to the decrease in morbidity that has occurred over recent years.     

Role of MRI in the early diagnosis of tubal ectopic pregnancy

Objective

To determine the role of MRI in the early diagnosis of tubal ectopic pregnancy (EP).

Methods

Clinical and MRI features of 27 cases of tubal pregnancy were reviewed.

Results

A thick-walled gestational sac (GS)-like structure was demonstrated lateral to the uterus in all cases. On T2-weighted images, the thick wall typically exhibited 3 discrete rings in 22 cases (81 %), among which 17 cases (63 %) displayed small vessels and 6 cases (33 %) exhibited small areas of fresh haemorrhage inside the thick wall. The contents demonstrated non-specific liquid in 26 %, papillary solid components in 56 %, and fresh blood or fluid-fluid level in 19 % of the cases. Dilatation of the affected fallopian tube associated with hematosalpinx was demonstrated in 18 cases (67 %) and marked enhancement of the tubal wall was observed in 22 cases (81 %). No correlation was found between the size of the GS and the estimated gestational age (r?=?0.056).

Conclusion

MRI plays an important role in the early diagnosis and management of tubal pregnancy. The characteristic MRI features include a GS-like structure with a “three rings” appearance on T2-weighted images, presence of solid components in the sac, dilatation of the affected fallopian tube with hematosalpinx, and tubal wall enhancement.

Key Points

? MR imaging has served as a problem-solving procedure in ectopic pregnancy. ? MR imaging features can be criteria for early diagnosis of tubal pregnancy. ? Detailed assessment of ectopic implantation is necessary for management decision-making.

     

Magnetic resonance imaging of tubal ectopic pregnancy: correlation with intraoperative findings

Ectopic pregnancy is defined as a pregnancy that occurs outside of the uterine cavity (ACOG Committee on Practice Bulletins, 2018 [1]). Ectopic pregnancy is occasionally diagnosed with MRI. Particularly, when ultrasound is nondiagnostic, it is essential that radiologists are able to recognize findings of ectopic pregnancy on MRI in the emergent setting. This novel case report demonstrates specific MR imaging signs recently proposed in the literature to help identify a tubal gestational sac, the most common type of ectopic pregnancy, and is the first reported case demonstrating intraoperative correlation with MRI findings of tubal ectopic pregnancy.