金属对金属全髋关节表面置换治疗中青年中晚期股骨头缺血性坏死

目的评价金属对金属全髋关节表面置换治疗中青年中晚期股骨头缺血性坏死(osteonecrosis of the femoral head,ONFH)的早期疗效,并与同期治疗单纯骨性关节炎疗效比较。方法回顾分析2006年7月-2008年10月行金属对金属全髋关节表面置换的33例45髋ONFH患者(ONFH组)临床资料,并与同期行金属对金属全髋关节表面置换的39例45髋骨性关节炎患者(骨性关节炎组)进行疗效比较。ONFH组:男18例27髋,女15例18髋;年龄19～58岁,平均42.7岁。有创伤史4例,糖皮质激素治疗史25例,吸毒史2例,酗酒史1例,银屑病1例。左侧22髋,右侧23髋。按Steinberg分期:Ⅲ期10髋,Ⅳa期18髋,Ⅳb期13髋,Ⅳc期4髋。Harris评分为(52.0±4.6)分。病程为1～12年。骨性关节炎组:男26例30髋,女13例15髋;年龄42～65岁,平均47.1岁。左侧17髋,右侧28髋。退行性骨性关节炎23例,创伤后骨性关节炎11例,强直性脊柱炎继发骨性关节炎5例。Harris评分为(57.0±3.8)分。病程为3～17年。两组患者一般资料比较差异均无统计学意义(P0.05),具有可比性。结果术后切口均Ⅰ期愈合,无感染、下肢深静脉血栓等并发症发生。患者均获随访,ONFH组随访时间平均26个月,骨性关节炎组平均28个月。术后4个月骨性关节炎组1例发生股骨颈骨折,改行人工全髋关节置换。其余患者均无明显假体松动、脱位,切口感染,骨坏死、吸收等并发症发生。末次随访时ONFH组Harris评分为(93.0±5.5)分,骨性关节炎组为(94.0±2.4)分;两组术后组间比较,差异无统计学意义(P0.05);组内手术前后比较,差异有统计学意义(P0.01)。结论金属对金属全髋关节表面置换治疗中青年中晚期ONFH近期临床效果满意,与治疗骨性关节炎效果相似,但仍需积累更多病例及长期临床随访验证中远期疗效。     

Clinical correlation of femoral component migration in hip resurfacing arthroplasty analyzed by Einzel-Bild-Röntgen-analyze-femoral component analysis

Hip resurfacing arthroplasty using metal-on-metal bearings has become increasingly popular. Wear of these bearings has been imperceptible on plain radiographs. Migration analysis studies may represent the opportunity to detect early failures and evaluate long-term prosthetic survival. The authors retrospectively reviewed 29 hips in a consecutive series of metal-on-metal hip resurfacing arthroplasties with a long-term clinical follow-up (average 8.7 years) to analyze the femoral component migration pattern by means of Einzel-Bild-R?ntgen-Analyze-femoral component analysis (EBRA-FCA). Femoral component migrations at 2 years and latest follow-up were compared with the known clinical outcomes. The authors' findings add validity to EBRA-FCA as a means to monitor femoral component migration and the clinical outcome of metal-on-metal hip resurfacing arthroplasty.     

Metal-on-metal hip resurfacing arthroplasty: A review of periprosthetic biological reactions

Metal-on-metal hip resurfacing arthroplasty has undergone a recent resurgence as an alternative treatment option for young and active patients with significant osteoarthritis. The claimed advantages of metal-on-metal hip resurfacing arthroplasty include lower wear rate, preservation of bone stock for subsequent revision procedures, restoration of anatomic hip mechanics, and enhanced stability due to the larger diameter of articulation. A disadvantage, however, is that the metal-on-metal resurfacing releases large amounts of very small wear particles and metal ions. The long-term biological consequences of the exposure to these Co-Cr particles and ions remain largely unknown. The purpose of this review is to provide an overview of the current literature on the adverse periprosthetic biological reactions associated with metal-on-metal hip resurfacing arthroplasty.     

Femoral component neck fracture after failed hip resurfacing arthroplasty

Failure on the femoral side after third-generation metal-on-metal hip resurfacing arthroplasty is suggested to be easily treated with conversion to conventional total hip arthroplasty. Clinical results of conversion for failed hip resurfacing arthroplasty with the use of primary femoral implants confirmed this for a short-term follow-up. We present a case of the occurrence of a stemmed femoral implant neck fracture in a patient who was earlier treated for a failed hip resurfacing. We advise to consider acetabular revision in case of (suspected) acetabular metal damage and to use a stem component with a relative large neck diameter.     

A Systematic Review of Modern Metal-on-Metal Total Hip Resurfacing vs Standard Total Hip Arthroplasty in Active Young Patients

This systematic review compared 2 treatments for hip disease in active young patients: modern metal-on-metal total hip resurfacing and standard total hip arthroplasty. We conducted a literature search to identify relevant randomized and clinical controlled trials and included 968 patients from 4 trials in our analysis. Our results indicated increased rates of revision, femoral neck fractures, and component loosening among patients who received modern metal-on-metal hip resurfacing. No significant differences in the rates of mortality, dislocation, or deep hip joint infection were found between treatment groups. Hip function scores were similar between the 2 groups, but the resurfacing group showed higher activity levels. These results have provided insufficient evidence to determine whether modern metal-on-metal total hip resurfacing offers clinical advantages over standard total hip arthroplasty.     

Femoral neck fractures complicating metal-on-metal resurfaced hips: a report of 2 cases

Metal-on-metal hip resurfacing arthroplasty is increasingly popular for younger patients with advanced hip disease. Intra-operative or immediate postoperative femoral neck fracture after metal-on-metal hip resurfacing is a well-described technical complication, ranging from 0% to 1.5%. We report 2 cases of late femoral neck fracture occurring 8 and 15 months following the index operation, with a review of the literature. We recommend that patient selection should be of prime importance before embarking on metal-on-metal surface hip replacement to avoid such complications.     

Treatment of the young active patient with osteoarthritis of the hip. A five- to seven-year comparison of hybrid total hip arthroplasty and metal-on-metal resurfacing

We compared the five- to seven-year clinical and radiological results of the metal-on-metal Birmingham hip resurfacing with a hybrid total hip arthroplasty in two groups of 54 hips, matched for gender, age, body mass index and activity level. Function was excellent in both groups, as measured by the Oxford hip score, but the Birmingham hip resurfacings had higher University of California at Los Angeles activity scores and better EuroQol quality of life scores. The total hip arthroplasties had a revision or intention-to-revise rate of 8%, and the Birmingham hip resurfacings of 6%. Both groups demonstrated impending failure on surrogate end-points. Of the total hip arthroplasties, 12% had polyethylene wear and osteolysis under observation, and 8% of Birmingham hip resurfacings showed migration of the femoral component. Polyethylene wear was present in 48% of the hybrid hips without osteolysis. Of the femoral components in the Birmingham hip resurfacing group which had not migrated, 66% had radiological changes of unknown significance.     

Metal-on-metal surface replacement: a triumph of hope over reason: affirms

Metal-on-metal hip resurfacing offers some potential for total hip arthroplasty (THA) in the young patient. However, short- and intermediate-term results of the currently available implants have failed to demonstrate advantage over conventional THA. The risks of femoral neck fracture or avascular necrosis have been disappointing early limitations of the procedure. The Australian Joint Registry reports a 5-year revision rate of all hip resurfacings of 3.8%, compared with conventional THAs at 2.8%, and a 9-year cumulative revision rate of 7.2% for hip resurfacings. Recent reports of femoral neck erosion and pseudotumors associated with resurfacing have raised concern about the survivorship of the procedure in some patients. Recently, the British Medicines and Healthcare Product Regulatory Agency issued an alert over adverse reactions associated with metal-on-metal THAs, with particular concern expressed about hip resurfacings. Acetabular bone stock may not be conserved when large-diameter femoral head components are used, depending on the surgical technique and implant design. In hip resurfacing, the minimum diameter femoral component avoids notching of the femoral neck; thus, larger diameter acetabular components may be necessary to accommodate the femoral component. Hip resurfacing is contraindicated in cases of avascular necrosis of the femoral head, especially with cysts >1 cm in diameter, with severe slipped capital femoral epiphysis, and in some posttraumatic arthroses; furthermore, the biomechanics of the resurfaced hip appear to be less reliably restored than with conventional THA. The hypothesis that resurfacing is a more conservative procedure than conventional THA remains unproven at this time. Given the documented intermediate failure rates of resurfacing, metal-on-polyethylene is the more successful implant choice.     

Finite element analysis of femoral neck stress in relation to pelvic width

Hip resurfacing arthroplasty has been developed as an alternative to traditional total hip arthroplasty, in an effort to minimize the loss of native bone in young patients with symptomatic hip osteoarthritis. Femoral neck fracture following hip resurfacing is a unique complication; several risk factors are associated with this complication, including female gender. In the present study, we used finite element models of the proximal femur to simulate stresses across the femoral neck in pelvis models with varying widths. This analysis demonstrated an increase in hip reaction forces as the width of the pelvis increases, a condition that simulates a resurfacing condition in a female pelvis. This difference in peak stress on the femoral neck may explain the increased incidence of femoral neck fractures seen in female patients following hip resurfacing.     

The effect of component size and orientation on the concentrations of metal ions after resurfacing arthroplasty of the hip

Increased concentrations of metal ions after metal-on-metal resurfacing arthroplasty of the hip remain a concern. Although there has been no proven link to long-term health problems or early prosthetic failure, variables associated with high metal ion concentrations should be identified and, if possible, corrected. Our study provides data on metal ion levels from a series of 76 consecutive patients (76 hips) after resurfacing arthroplasty with the Articular Surface Replacement. Chromium and cobalt ion concentrations in the whole blood of patients with smaller (or= 53 mm) components (p < 0.01). Ion concentrations in the former group were significantly related to the inclination (p = 0.01) and anteversion (p = 0.01) of the acetabular component. The same relationships were not significant in the patients with larger femoral components (p = 0.61 and p = 0.49, respectively). Accurate positioning of the acetabular component intra-operatively is essential in order to reduce the concentration of metal ions in the blood after hip resurfacing arthroplasty with the Articular Surface Replacement implant.     

Hip Resurfacing With the Biomet Hybrid ReCap-Magnum System: 7-Year Results

The purpose of this study was to report our clinical outcome of a large series of metal-on-metal hip resurfacing arthroplasty (HRA) using the hybrid Biomet ReCap-Magnum system. This is a single-designer surgeon series with an average of 5 ± 1 years. Seven hundred forty consecutive hybrid HRAs were performed in 653 patients. Kaplan-Meier survivorship with any revision as an end point was 96.4% at 7 years. Twenty-five (3.4%) cases were revised: 8 due to acetabular component loosening, 6 due to femoral neck facture, 4 due to failure of femoral component fixation, 2 due to deep infection, 2 due to adverse wear, 1 due to psoas tendonitis, 1 due to recurrent dislocation, and 1 due to unexplained pain. Biomet ReCap and Magnum HRA components with hybrid fixation methods showed excellent survivorship for a minimally selected young patient cohort at 7 years.     

Total hip arthroplasty in osteopetrosis using computer-assisted fluoroscopic navigation

Hybrid total hip arthroplasty with computer-assisted fluoroscopic navigation was performed on a patient with osteoarthritis due to an autosomal dominant form of osteopetrosis. The surgical procedures were difficult because the bone was extremely hard and brittle with obliteration of the medullary cavity. Especially, preparation of a femoral canal for the stem was technically challenging and required changes from a conventional surgical procedure. Therefore, we used a computer-assisted fluoroscopic navigation system to create the femoral cavity for the stem, and an accurate placement of the prosthesis was achieved. Navigation guidance can be a useful tool when performing arthroplasty in patients with hip osteoarthritis associated with osteopetrosis.     

A simple technique for avoiding femoral component malpositioning in total hip resurfacing arthoplasty

Proper femoral component orientation and positioning are crucial in avoiding early complications of total hip resurfacing arthroplasty. Fluoroscopic verification of guide-wire positioning helps avoid femoral component malpositioning but is technically difficult using standard protocols. In this article, we describe a simple technique that allows for fluoroscopic verification of guide-wire positioning. This technique is useful within the learning curve for total hip resurfacing arthroplasty.     

Metal ion levels decrease after revision for metallosis arising from large-diameter metal-on-metal hip arthroplasty

Concerns have been renewed regarding the possible long-term effects of elevated circulating levels of cobalt and chromium as a direct result of implantation of large femoral head diameter metal-on-metal bearings. In order to establish whether metal ion levels remain persistently elevated, we compared metal ion levels before and after revision surgery in patients with large head diameter (greater than 38 mm) metal-on-metal total hip arthroplasty or hip resurfacing arthroplasty. At greater than one year post removal of a large-diameter metal-on-metal hip implant for the indication of symptomatic metallosis, metal ion levels were found to fall to almost normal levels.     

Resurfacing hip arthroplasty. A 3 to 5-year matched pair study of two different implant designs

We compared the 3 to 5 year clinical and radiological results of two different hybrid metal-on-metal resurfacing hip arthroplasty designs in 28 patients who had undergone bilateral hip resurfacing with ReCap implants on one side and BHR implants on the other side. Both hips were compared in each patient, to specifically evaluate the bone response to the cemented femoral component. Post operative function was measured with the Harris Hip Score and University of California at Los Angeles (UCLA) Activity Score, and was excellent in these patients. Mean cup inclination was 43.3 degrees +/- 7 degrees (43.3 degrees +/- 7 degrees for the BHR and 43.4 +/- 6 degrees for the Recap). The inclination angle was greater than 45 degrees in 15 patients: 7 with a BHR, 8 with a Recap; eight patients showed inclination angles greater than 50 degrees (4 patients in each group). All acetabular monoblock cups were well fixed. One patient (1.8%) had radiographs showing bone changes of uncertain significance around the stem of the femoral component. Three percent had femoral bone resorption in the BHR hip and two percent showed bone resorption in the ReCap hip. There was no evidence of migration of the femoral components. The dual energy X-ray absorptiometry (DEXA) scans identified no real reduction in bone density in these resurfacing hip arthroplasties. None of these hips showed any other adverse features. The biological response showed no difference for the two different designs of resurfacing hip arthroplasties.     

Hip Resurfacing With the Biomet Hybrid ReCap-Magnum System : 7-Year Results

The purpose of this study was to report our clinical outcome of a large series of metal-on-metal hip resurfacing arthroplasty (HRA) using the hybrid Biomet ReCap-Magnum system. This is a single-designer surgeon series with an average of 5 ± 1 years. Seven hundred forty consecutive hybrid HRAs were performed in 653 patients. Kaplan-Meier survivorship with any revision as an end point was 96.4% at 7 years. Twenty-five (3.4%) cases were revised: 8 due to acetabular component loosening, 6 due to femoral neck facture, 4 due to failure of femoral component fixation, 2 due to deep infection, 2 due to adverse wear, 1 due to psoas tendonitis, 1 due to recurrent dislocation, and 1 due to unexplained pain. Biomet ReCap and Magnum HRA components with hybrid fixation methods showed excellent survivorship for a minimally selected young patient cohort at 7 years.     

The effect of hip resurfacing on oxygen concentration in the femoral head

We inserted an electrode up the femoral neck into the femoral head of ten patients undergoing a metal-on-metal hip resurfacing arthroplasty through a posterior surgical approach and measured the oxygen concentration during the operation. In every patient the blood flow was compromised during surgery, but the extent varied. In three patients, the oxygen concentration was zero at the end of the procedure. The surgical approach caused a mean 60% drop (p < 0.005) in oxygen concentration while component insertion led to a further 20% drop (p < 0.04). The oxygen concentration did not improve significantly on wound closure. This study demonstrates that during hip resurfacing arthroplasty, patients experience some compromise to their femoral head blood supply and some have complete disruption.