球状快套附着体固位可摘局部义齿的临床应用

目的为了探讨球状快套附着体在可摘局部义齿的临床应用。方法作者对9名游离端缺失的患者利用20颗基牙用球状快套冠外附着体26个，2颗基牙用桩帽附着体2个，桥接片按扣式附着体2个，制作12件球状快套固位义齿。经3个月至2年时间的临床观察。结果发现附着体能很好地保护基牙，其固位的活动义齿稳定性能好，咀嚼效率高，美观舒适卫生。结论球状快套附着体固位可摘局部义齿是一种固定一活动联合修复体，兼有固定和活动义齿的优点，值得临床推广应用。     

SG球状快套附着体义齿修复游离端牙列缺损15例

目的 观察SG球状快套附着体义齿修复游离端牙列缺损的临床效果。方法 15例游离端牙列缺损病例，应用SG球状快套附着体固位的义齿进行修复。结果 经6月至5年的临床随访：SG球状快套附着体固位的义齿稳定性能好，固位力强，咀嚼效率高，美观，舒适，耐用，摘戴方便，并发症少。结论 SG球状快套附着体义齿是修复游离端牙列缺损的较好方法。     

球状快套附着体固位可摘局部义齿的临床应用

为了探讨球状快套附着体在可摘局部义齿的临床应用。方法 作者对９名游离端缺失的患者利用２０颗基牙用球状快套冠外附着体２６个，２颗基牙用桩帽附着体２个，桥接片按扣式附着体２个，制作１２件球状快套固位义齿。经３个月至２年时间的临床观察。结果 发现附着体能很好地保护基牙，其固位的活动义齿稳定性能好，咀嚼效率高。，美观舒适卫生。     

MAGFIT磁性附着体的临床应用及疗效观察

目的：观察Magfit磁性附着体用于全口覆盖义齿和可摘局部覆盖义齿的修复疗效。方法：为20名患者制作31只Magfit磁性附着体，对义齿的固位，咀嚼和使用情况进行为期2年的随访观察。结果：31只磁性附着体均在正常使用，其义齿的固位力，稳定性，咀嚼功能良好，基牙健康。结论：Magfit磁性附着体能提高义齿的固位力及咀嚼效率，缩短义齿的适应期，保护基牙的健康，美观效果好，显著提高了义齿的修复质量。     

磁性附着体在12例牙列缺损修复中的应用

目的应用磁性附着体固位可摘义齿修复牙列缺损,探讨其临床修复效果。方法采用Magfit磁性附着体,为12例牙列缺损患者制作磁性附着体固位可摘义齿。结果随访1～4年,12例患者中,除1例基牙松动度增加外,余11例均感义齿美观舒适,固位稳定性强,咀嚼功能好,检查基牙无病变。结论采用磁性附着体固位义齿修复效果良好。     

磁性附着体在覆盖义齿修复中的临床应用

评价Magfit磁性附着体改善总义齿和局部覆盖义齿固位的效果。方法：采用铸接法设置根面衔接,对使用Magfit磁性附着体覆盖义齿的病例,进行12－18个月的随访观察,结果：10件总义齿采用了2－4枚磁体,固位效果满意或良好;2件总义齿采用了1枚磁体,固位也得到改善,6件局部义齿均采用1枚磁体,固位满意,采用Magfit磁体固固位的覆盖义齿并发症少。结论：Magfit磁性附着体能够改善总义齿和局部覆盖义齿的固定与稳定,且并发症少。     

球状快套根面附着体在全口覆盖义齿修复中的应用

目的 观察球状快套根面附着体应用于全口覆盖义齿修复的临床疗效.方法 77例仅存少数残冠或残根的患者,制作92件球状快套根面附着体全口覆盖义齿,每件义齿设计1～4枚根面附着体,临床观察1～6年.结果 92件球状快套根面附着体全口覆盖义齿美观、舒适,固位稳定性好,咀嚼效率较高.其中单颌全口义齿中固位稳定效果在良好以上者84件,占91.3%, 19件出现并发症,有塑料帽套脱落、根桩钉松动脱落、义齿局部基托折裂.结论 球状快套根面附着体是一种较好的全口覆盖义齿修复的固位体.     

超瓷根帽结合磁性附着体在覆盖义齿中的临床应用

目的：观察Targis瓷聚体根帽结合磁性附着体用于牙列缺损患者的修复疗效。方法：49名患者制作58件磁性附着体,对义齿的固位、牙龈健康状况及衔铁有无脱落进行为期2年的随访观察。结果：磁性附着体磁力无削弱,义齿稳定性好。结论：Targis瓷聚体超瓷根帽结合Magfit磁性附着体能提高义齿的固位力,工艺学步骤简单,保护附着体的磁力不被削弱,可提高义齿的修复质量。     

缓冲型冠外附着体义齿修复游离端牙列缺损的临床研究

目的 评价冠外附着体固位型可摘局部义齿修复肯氏工类和Ⅱ类牙列缺损的修复效果。方法 采用vario-sofisnapOCorSG附着体，为30例肯氏工类牙列缺损和12例肯氏Ⅱ类牙列缺损患者制作50件弹性冠外附着体，观察其修复效果。结果 随访6个月-10年，患者均感觉冠外附着体固位型可摘局部义齿美观，舒适、固位稳定性好，咀嚼效能高，有利于基牙和支持组织的健康。结论 缓冲型冠外附着体固位型可摘局部义齿修复游离端牙列缺损，长期修复效果好，有较好的临床应用前景。     

精密附着体固位型可摘义齿

目的:介绍精密附着体固位型义齿的设计原则,制作方法,评价其临床效果。方法:采用Bredent球状和杆状精密附着体系统,为21名患者设计制作了30件义齿,53副精密附着体。结果:最长者经3年零10个月观察,临床效果良好。结论:患者戴用该型义齿后,咀嚼功能好,稳固、摘戴方便、美观舒适,基牙无病变     

柠檬精油对牙周致病菌抑制作用及其安全性初步研究

目的:探讨柠檬精油对牙周致病菌的体外抗菌活性及对细胞增殖的影响。方法:采用微量液体稀释法测定柠檬精油对Pg、Fn、Aa、Pi的最小抑菌浓度(minimal inhibitory concentration,MIC)及最小杀菌浓度(minimum bactericidal concentration,MBC);以较低浓度的MIC为标准稀释LEO作为实验组,采用MTT法测定柠檬精油对HUVECs的毒性作用,明确抑菌浓度下LEO的安全性。结果:柠檬精油对牙周主要致病菌均有抑菌作用,Pg、Fn、Aa、Pi的MIC分别是9.0 g/L、4.5 g/L、4.5 g/L、9.0 g/L,Aa、Fn的 MBC是9.0 g/L,Pg、Pi的MBC未测得。1/2MIC、1/20MIC浓度的LEO能够抑制人脐静脉内皮细胞的生长,而低于1/200MIC浓度的LEO则对人脐静脉内皮细胞的生长没有影响,其中1/200MIC浓度的LEO作用明显优于0.02%的CHX。结论:体外环境中,柠檬精油对牙周致病菌Pg、Fn、Aa、Pi具有抗菌活性,低浓度应用对机体相对安全。     

Oral cancer: molecular technologies for risk assessment and diagnosis

Purpose: The effective biomarkers related to diagnosis, metastasis, drug resistance and irradiation sensitivity of oral cancers will help the pathologist and oncologist to determine the molecular taxonomy diagnosis and design the individualization treatment for the patients with oral cancers.     

Computer-assisted planning for maxillofacial prosthodontic rehabilitation

Computerized tomography (CT) planning and the use of CT derived surgical templates for implant placement have shown promise for restoring function within months after surgical reconstruction of acquired post-oncologic defects.     

Stimulated whole saliva components in children with Down syndrome

The authors report on the components of stimulated whole saliva from children with Down syndrome—including pH, flow rate, sialic acid and protein concentrations, and amylase and peroxidase activity. Saliva samples were collected from 35 children aged 6–10 years. Of the participants, 17 had Down syndrome and 18 did not. To stimulate saliva production, the children chewed a piece of parafilm for 10 minutes before the sample was collected. Soon after collecting the saliva sample, the authors measured pH using a portable pH-meter. Sialic acid levels were determined with a thiobarbituric acid assay. Protein content was determined with Folin's phenol reagent. Amylase was assayed and the authors measured the maltose produced by the breakdown of starch and peroxidase using ortho-dianisidine.
No statistically significant difference was observed in levels of sialic acid (free and total) between the two groups. Protein concentration was about 36% higher in the group with Down syndrome. However, the salivary flow rate, pH, and amylase and peroxidase activities were lower among the children with Down syndrome.     

Effect of Pingyangmycin on human venous malformation endothelial cells

Purpose: Venous malformations are common vascular anomalies with a propensity of the head and neck. Intralesional injection of Pingyangmycin (PYM, bleomycin A5 hydrochloride) is a widely used sclerotherapy method for the treatment of venous malformation.     

牙髓再生的研究现状

目前,根管治疗术在临床上已得到了广泛的应用并成功的保存了患牙,但其仍有许多术后并发症。随着组织工程技术在口腔领域的应用,构建一种组织工程化牙髓进行牙髓-牙本质复合体的再生治疗成为可能。近年来国内外已有很多关于牙髓再生的研究,并且已经取得了一定成果。本文将对目前国内外牙髓再生的研究进展现状作一综述。     

替牙期骨性Ⅲ类错牙合患者颞下颌关节特征的锥形束CT研究

目的:采用锥形束CT(CBCT)研究替牙期骨性Ⅲ类错牙合患者颞下颌关节的影像学特征,探讨Ⅲ类功能状态下,颞下颌关节的生长、改建机制。方法:从就诊于昆明医科大学附属口腔医院正畸科的患者中选取符合纳入标准的替牙期骨性Ⅲ类错牙合患者及骨性Ⅰ类错牙合患者各20名,使用NNT viewer 5.3图像处理软件进行三维重建及线距和角度的测量,并进行统计学分析。结果:替牙期骨性Ⅲ类错牙合患者组和替牙期骨性Ⅰ类错牙合患者组对比结果为:矢状面双侧关节前间隙偏小、双侧关节上间隙偏小、双侧关节结节斜度偏小;冠状面双侧关节内间隙偏小,双侧关节上间隙偏小,双侧关节外间隙偏小,右侧髁状突角度偏小;横截面右侧髁状突前后径偏小。结论:替牙期骨性Ⅲ类错牙合患者颞下颌关节发育不充分,呈现髁状突,关节窝深度,关节结节斜度;冠状面关节内、外间隙均较小的特征。骨性Ⅲ类错牙合患者髁状突在关节窝中处于前置近关节窝顶位置。骨性Ⅲ类错牙合患者颞下颌关节影像学特征与其功能状态相适应。     

Ghlorhexidine as a root canal medicament for treating inflammatory lesions in the periodontal space

Abstract— The purpose of the present study was to investigate the therapeutic effect of intra-canal application of chlorhexidine on inflammatory root resorption. Dental pulps from monkey incisors were infected and resealed prior to extraction of the teeth. Root dentin was mechanically exposed and the teeth were replanted under aseptic conditions. After 4 weeks, the experimental teeth were dressed with chlorhexidine gel and resealed. Animals were sacrificed 4 weeks later, and their jaws prepared for histologic examination. Results showed that both marginal and apical periodontal inflammation and resorption were reduced in the chlorhexidine-treated teeth. It was concluded that the use of intra-canal chlorhexidine may be a useful adjunct in the treatment of inflammatory root resorption, but further human trials need to be undertaken before its clinical use can be recommended.     

小鼠牙髓干细胞同种异体移植后体内免疫反应初探

目的:初步探究小鼠牙髓干细胞同种异体移植后的全身免疫反应。方法:牙髓干细胞分离获得自C57BL/6 小鼠牙髓组织,培养至第3 代,与纳米羟基磷灰石(n-HA)复合培养形成复合物,扫描电镜观察其生长黏附情况。40只4周龄的C57BL/6 小鼠随机分成两组。实验组将复合物移植入上背部皮下,对照组将纳米羟基磷灰石植入上背部皮下,术后均使用外科方法严密缝合创口。两组动物术后均观察4周、6周处死,分离脾脏,制成脾淋巴细胞悬液,流式细胞仪测定CD4⁺、CD8⁺的值。结果:牙髓干细胞在体外与纳米羟基磷灰石结合良好;免疫组化染色实验组4周、6周均可见牙本质涎蛋白(dentin sialoprotein,DSP)阳性表达;实验组与对照组相比,术后4周、6周CD4⁺/CD8⁺值均无明显差异。结论:牙髓干细胞同种异体移植后,尚不能够引起机体的免疫排斥反应,其在体内仍具有低免疫原性,有望成为组织工程同种异体种子细胞来源。