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1.
Skeletal maturity is evaluated by many radiological methods for forensic age estimation. Direct radiography and computed tomography lead to a rise in ethical concerns due to radiation exposure. Therefore, magnetic resonance imaging (MRI) has currently been used in recent studies. In this study, the ossification stage of the shoulder joint was determined retrospectively in 178 male and 109 female individuals in the age group 12 to 30 years using 3.0 T MRI. All the images were evaluated with T1-weighted turbo spin echo (T1 TSE) sequence and T1 fast low angle shot two-dimensional sequence (T1 FL2D). The combined staging method, which was defined by Kellinghaus et al. and Schmeling et al., was used. The intra- and inter-observer agreement levels were very good (κ and κ w). There were no significant age differences between males and females in all stages. In most of the stages, the ossification of the proximal humeral epiphyses occurred earlier in females than in males. Stage 4 did not occur in either of the sexes before the 18th birthday as the youngest patients in this stage was at 19 and 18 years of age in males and females, respectively. We concluded that evaluating the ossification of the proximal humeral epiphysis with MRI imaging for forensic age estimation may be beneficial. Evaluating the same anatomical structure with different MRI sequences may be useful for accurate staging diagnosis. 相似文献
2.
The establishment of radiation-free examination procedures in the field of forensic age diagnostics in living persons is to be considered of special scientific interest so as to minimize necessary exposure to X-rays while facilitating additional assessment of skeletal development in all cases. To this end, the advantages offered by magnetic resonance imaging in securing a practical application which is as unrestricted and complication-free as possible should be among the methods exploited in investigating such indicators of skeletal maturity. Within the framework of a retrospective study, we investigated the ossification status of the proximal tibial epiphysis on the MRI scans of 124 females and 166 males aged between 10 and 30 years. All the images had been generated on a 3.0 T scanner using a T1-weighted turbo spin-echo sequence. When evaluating the ossification stage, a combination of modified classifications proposed by Schmeling et al. and by Kellinghaus et al. was used. The statistical evaluation included calculation of a variety of measures to describe specific ossification stages as well as kappa coefficients to assess intra- and inter-observer agreement on diagnoses of individual stages. In forensic contexts, completion of the 14th year of life can be adequately evidenced in females with an ossification stage IV according to Schmeling et al. and in males with an ossification stage III c according to Kellinghaus et al. or an ossification stage IV according to Schmeling et al. In forensic contexts, the presence of an ossification stage IV according to Schmeling et al. can prove that the age of 16 years has been exceeded only in the male sex, whereby for age estimation purposes the diagnosis should be in line with other skeletal maturity indicators. The results available displayed a high degree of intra- and inter-observer agreement. Examination of the ossification status of the proximal tibial epiphysis using magnetic resonance imaging represents an effective additional tool for use in radiation-free forensic age diagnostics in living persons. 相似文献
3.
To improve the accuracy of forensic age estimation where there is no legal basis for carrying out x-ray examinations, it would be useful to establish non-x-ray imaging techniques. The objective of this study was to provide reference data for the magnetic resonance imaging-based evaluation of the ossification stage of the distal radius. Furthermore, we tested a new criterion of the maturity of the distal radial epiphysis for determining whether an individual has completed the age of 18. We investigated 668 MRI scans of the distal radial epiphysis from 333 female and 335 male subjects ranging in age from 12 to 24. To determine the ossification stage, we used the clavicular ossification staging systems described by Schmeling et al. and Kellinghaus et al. Ossification stage IV as described by Schmeling et al. was divided into two sub-stages, IVa and IVb, depending on whether or not it was possible to identify a triple-banded meta-epiphyseal zone of calcification. All study subjects were able to be assigned to an ossification stage without ambiguity. We present statistics relating to the distribution of ossification stages divided by sex. The age of the youngest female subject assessed as ossification stage IVb was 16.8, the age of the youngest male subject 18.6. The youngest age at which female subjects were assessed as ossification stage V was 22.3; for male subjects it was 23.1. Further independent studies should be carried out to determine whether ossification stage IVb can indeed be used to reliably determine whether a male subject has completed the age of 18. 相似文献
4.
Thin-slice computed tomography provides the imaging modality of choice in analysing the ossification process of the medial clavicular epiphysis for the purpose of forensic age diagnostics in the living in the course of criminal proceedings. The classification of the ossification stages by Schmeling et al. compass the emergence of an epiphyseal ossification centre (stage 2), the partial fusion of the epiphysis with the metaphysis (stage 3), the complete fusion of these osseous elements including a visible epiphyseal scar (stage 4), and the complete fusion without a visible epiphyseal scar (stage 5). In the present study, each of the ossification stages 2 and 3 was divided into an early, intermediate and late phase. The authors evaluated the thin-slice CT scans of 185 patients aged between 13 and 26 years. In all these cases, a stage 2 or 3 had been determined in a previous study. The late stage 3, which is characterized by a fusion between metaphysis and epiphysis completing more than two thirds of the former epiphyseal gap, first appeared at age 19 in both sexes. If a late stage 3 is found, it is therefore possible to substantiate that an individual has already reached the legally important age threshold of 18 years. 相似文献
5.
Establishing radiation-free imaging methods for the assessment of clavicular ossification in forensic age determination is desirable as it reduces radiation exposure in living individuals. For this purpose the stage of ossification of the right medial clavicular epiphysis was determined prospectively using sonography in 309 male and 307 female healthy volunteers. The classification of stages according to Schulz et al. was used for this purpose. Stage 2 was first noticed at the age of 14.4 years in males, and at the age of 14.1 years in females. Stage 3 was first achieved by males at the age of 17.6 years and by females at the age of 17.4 years. Stage 4 first occurred in males at the age of 19.3 years and at the age of 18.9 years in females. The mean age for stage 1 was 13.6 years. The mean age of stage 2 ranged between 17.3 and 17.6 years. For stage 3 the mean age varied from 20.7 to 21.2 years, and for stage 4 from 23.3 to 23.5 years. It was concluded that sonographically determined stage 4 clavicular ossification provides evidence for the completion of the nineteenth year of life in males and the eighteenth year of life in females. In order to increase the reliability of age determination using this method it is recommended that findings be recorded by at least two experienced independent examiners who then reach a consensus. 相似文献
6.
Due to the increasing significance of forensic age estimations in the age of globalisation, novel radiographic criteria besides clavicles and hand bones may provide additional certainty for forensic age expertises. The present study analyses the suitability of the iliac crest apophysis by means of 643 pelvic radiographs of patients between 10 and 30 years of age. Retrospective assessments were carried out according to the forensically established classification and sub-classification systems modified after Kreitner et al. (Rofo 166(6):481–486, 1997) and Kellinghaus et al. (Int J Legal Med 124(4):321–325, 2010). The basic ossification stages range from 1 to 4, and the sub-stages of stage 2 and 3 range from a to c. While stage 3c was first achieved at the age of 15 by both sexes, stage 4 was first observed in females at the age of 16 and in males at the age of 17. This indicates the possibility of a valid diagnosis of both the age of 14 and the age of 16 years which represent legally relevant age thresholds in numerous countries. Applied as targeted radiography on the iliac crest, the exposure to radiation would range between other radiographic techniques recently applied. Therefore, the iliac crest apophysis appears principally suitable as novel possible criterion for forensic age estimation in the living. However, for the establishment of the iliac crest apophysis in routine diagnostics, further studies are needed focussing on the comparison of different grading systems and different radiological techniques. 相似文献
7.
The authors retrospectively analyzed 629 CT images of patients aged between 15 and 30 years produced during multiple trauma diagnostics at the Unfallkrankenhaus Berlin. For the purposes of this study, the authors reliably determined the ossification status of the medial epiphysis of the clavicle in 556 cases, using the classification of stages by Schmeling et al. In both sexes, stage 2 was first noted at age 15. In male patients, the earliest occurrence of stage 3 was noted at age 17, in female patients at age 16. Stage 4 was first achieved by both sexes at age 21. Stage 5 was first noted in female patients at age 21 and in male patients at age 22, which is 4 or 5 years earlier than was observed by a comparable study using conventional radiographs. The partial-volume effect in computed tomography using the thick slice scanning mode was discussed as a possible explanation for this early visualization. The question of how slice thickness affects the age intervals between ossification stages identified by CT examinations should be examined in additional studies. 相似文献
8.
There is an increasing demand for age estimations of living persons who are involved in civil and criminal procedures but lack a valid birth certificate indicating their date of birth. Several studies have recommended the application of magnetic resonance imaging (MRI) and assessment of the stage of epiphyseal fusion in age estimation. This study involved retrospective MRI analysis of 335 cases (217 males and 118 females) whose ages ranged from 8 to 28 years (yrs). We assessed the degree of ossification of the proximal tibial epiphysis depending on the classifications of Schmeling and Kellinghaus used for the main stages (I, II, III, IV & V) and substages (IIa, b, c & IIIa, b, c). Significant differences between males and females at stages IIIc, IV and V (p < 0.001) were observed. Additionally, the ossification of the proximal tibial epiphyses occurred earlier in females than in males (2–4 yrs). The mean of ages in stage IV was approximately 18.6 yrs. in females and 22.5 yrs. in males, meaning that stage IV can be used as a valuable forensic marker to determine whether the person in question has reached the age of 18 yrs. We concluded that the application of MRI in the assessment of the ossification status of the proximal tibial epiphysis could be helpful in age estimation for various forensic purposes. 相似文献
9.
Determination of the stage of ossification of the medial clavicular epiphysis is a crucial part of age estimation in criminal
proceedings when evaluating individuals with completed hand ossification. In order to ensure a maximum of accuracy in forensic
age estimation practise, it is recommended to perform thin-slice CT scans; but to date there exist no reference data on the
bone development of the region in question based on thin-slice computed tomography. In this retrospective study, the authors
evaluated thin-slice multidetector CT images of 592 individuals aged between 10 and 35 years produced in the University Hospital
of Münster. The ossification status of the medial epiphysis of the clavicle could be reliably determined in 502 cases using
the classification of stages by Schmeling et al. In male individuals, stage 2 was first noted at age 14, in female individuals
at age 13. Stage 3 was first achieved by male individuals at age 17, by female individuals at age 16. The occurrence of stage
4 was first found in both sexes at the age of 21. In either sex, the earliest observation of stage 5 was at age 26. The findings
are basically in line with those from the only CT-based study on the subject in question using the same classification of
five stages, except from the fact that in the present study, stage 5 first occurs at age 26, which is 4 or 5 years later than
what was found in the CT study using 7 mm slices in the majority of cases. This vast difference may be explained through the
partial volume effect occurring with thick-slice CT images by a visual deception of the epiphyseal scar occurring with stage
4. 相似文献
10.
Radiological analysis of the hand skeleton is a key pillar of forensic age diagnostics in living subjects undergoing criminal
proceedings. The present study investigated whether ossification stage classification of selected epiphyses of the hand could
provide added value to hand radiograph analysis. Hand radiographs from 265 male and 164 female subjects aged 10–18years old
who had been X-rayed due to traumatological indications were therefore assessed. Epiphyseal ossification of selected elements
of the hand skeleton (ulna, radius and third metacarpal, basal phalanx, mesophalanx and telephalanx) was graded based on the
criteria of the five-stage classification system of Schmeling et al. (Int J Legal Med, 118:5–8, 2004) for clavicular epiphyseal
cartilage. Stage 5 (absence of the epiphyseal scar) does not occur in the radius of men before the age of 18. Stage 5 can
therefore be regarded as a potential parameter for valid determination of a minimum age of 18 years for forensic age estimation
in criminal proceedings. 相似文献
11.
In this study, both medial clavicular epiphyses of 77 men were evaluated by two researchers with a digital ultrasound system.
The degree of ossification was classified in four stages according to Schulz et al. (Int J Legal Med 122:55–58, 17). Of the test persons over 21 years of age, stage 4 was found bilaterally in 25 (60%), while for five (12%) stage 4 was found
on only one side; 12 (28%) further subjects did not show stage 4 on either side, although nine were exactly 21 years old.
For the subjects under 21 years of age, stage 4 was found bilaterally in three cases (8.5%), and in three additional cases
stage 4 was found on one side. Particularly, the three cases in which stage 4 was diagnosed bilaterally before completion
of the 21st year of age limit the value of the used examinatory technique. For these cases it would be interesting to know
if parts of the epiphyseal plate that might have been obstructed from the view of the ultrasound transducer would have been
visible with CT. 相似文献
12.
The assessment of the ossification status of the medial clavicular epiphysis plays a decisive role in forensic age diagnostics to determine whether a person has completed his or her 18th or, respectively, 21st year of life. Currently, computed tomography is the gold standard method for age diagnostics of this kind. However, efforts are being made to establish non-ionizing methods, such as ultrasonography, predominantly, in an attempt to reduce the radiation exposure load of living persons. The present study is the first to score and to compare the ossification status of both medial clavicular epiphyses of the same subjects by sonography, computed tomography, and, in some of the cases, by macroscopy. Our study was conducted on five male corpses, ranging in age from 15.8–28.8 years. In the comparison of high-resolution sonography (frequency, 12–15 MHz) and thin slice computed tomography (slice thickness, 0.6 mm), performed separately for left and right clavicles, the results from these two methods differed in seven of ten cases. In six cases, the ossification stage of the medial clavicle, determined by sonography and classified according to Schulz et al. (2008), was scored higher than with computed tomography. In one case, it was rated lower. There was only one subject for whom both the sonographic and computed tomography findings agreed for both body sides. 相似文献
13.
When preparing forensic age estimates for living subjects over 18 years of age, it is crucial to evaluate the stage of ossification
of the medial clavicular epiphysis. The establishment of radiation-free imaging techniques for assessment of clavicular ossification
would be desirable in order to reduce the radiation exposure associated with forensic age estimations. In the present study,
84 right clavicles of test subjects 12–30 years of age were prospectively evaluated by means of ultrasound. Ossification stage
classification was possible in 80 of the 84 medial clavicular epiphyses studied. In the remaining cases, stage classification
was not possible due to the presence of developmental anomalies. The earliest ages at which the respective ossification stages
were observed were 17.1 years for stage 2, 16.7 years for stage 3, and 22.5 years for stage 4. The age intervals observed
for the ossification stages are consistent with the known data from radiological and computed tomography assessments. The
present study results should be confirmed in a larger number of cases and with analysis of observer variability. Evaluation
of medial clavicular epiphyseal ossification by ultrasound could ultimately be a rapid and economic non-ionizing diagnostic
imaging procedure for forensic age estimation. 相似文献
14.
By determining the ossification stage of the distal radial epiphysis, it is possible to gain important information to help clarify the question of whether various legally relevant age limits have been exceeded. Any examination of the hand by means of projection radiography such as that used in conventional skeletal age diagnostics is strictly regulated for reasons of radiation hygiene. In many areas of the law, there are no basic legal provisions authorising the performance of X-ray examinations. The present study examines the applicability of ultrasound diagnostics in assessing ossification processes in the distal radius. To this end, the ossification stages of the distal radial epiphysis were determined in 306 female and 309 male study participants aged between 10 and 25 years. In the female gender, ossification stage III was determined at an age of 13.4 years at the earliest, and ossification stage IV at 15.0 years at the earliest. In the male gender, ossification stage III was not observed until 14.3 years, and ossification stage IV not until 15.2 years. In the practice of forensic age estimation in living persons, sonographic examination of the distal radius in areas of application with no legal basis for authorising X-ray examinations makes it possible to improve the accuracy of age diagnosis by including criteria of skeletal maturation. In view of the existing legislative basis for the use of X-rays on human subjects, the exposure of individuals to radiation can be minimised. 相似文献
15.
Due to increasing international migratory movements, forensic age estimations of living individuals in criminal proceedings are gaining increasing significance for forensic physicians and radiologists involved in delivering expert opinions. The present study examines the suitability of the radiologically well-known Risser sign grading as a possible new criterion in forensic age diagnostics. For this purpose, anteroposterior pelvic radiographs of 643 patients aged between 10 and 30 years were retrospectively evaluated by means of two different Risser sign grading systems (US and French), each with 5 stages. The left and right sides of the pelvis were assessed separately. The data was analyzed with separation of the sexes. Reliable Risser sign determination was possible in 566 cases. In both sexes, stage 4 of both the US and the French grading systems was predominantly first noted at age 14 years. In the US grading system, stage 5 was also first achieved at age 14 years in the majority of both sexes. In the French grading system, females manifested stage 5 at a minimum of 16 years, whereas in males it was first observed at 17 years. As to the nature of iliac crest maturation, interesting deviations were observed at stages 1 and 5, raising doubts about Risser’s ossification process. To conclude, both Risser sign grading systems are suitable for forensic age diagnostics, especially to determine whether the 14th year of life has been completed or not. The French Risser sign system additionally allows for statements as to the completion of the 16th year of age. 相似文献
16.
Computed tomography scans originally obtained to assess the ossification status of the medial clavicular epiphyses of 40 live
subjects for forensic age estimation purposes were analysed. From the data acquired we reconstructed images with slice thicknesses
of 1, 3, 5 and 7 mm, and based on the classification of stages by Schmeling et al. (Int J Legal Med 118:5–8, 2004), we determined
the ossification stage for each reconstructed slice thickness, separately for both sides. Of the 80 clavicular epiphysial
plates examined, seven displayed slice-thickness-dependent differences at certain ossification stages. In one case a slice
thickness of 1 mm led to a different diagnosis of the ossification stage than a slice thickness of 3 mm, in three cases the
diagnoses differed between the slice thicknesses of 3 and of 5 mm, and in another three cases, between 5 and 7 mm. We therefore
conclude that for age estimation purposes, the slice thickness should be 1 mm to ensure maximum accuracy and diagnostic reliability. 相似文献
17.
Age estimation by third molar mineralization has been developed for a period of time. Recent studies showed that impaction status has an influence on the rate of the third molar mineralization in Europids and male Black African populations. In this regard, the present study was conducted to determine whether the impaction status could delay the chronological process of third molar mineralization in northwestern Chinese population too. A total of 3,512 digital orthopantomograms of 1,255 male and 2,257 female northwestern Chinese subjects aged from 11 to 26 years were assessed based on the formation stages described by Demirjian et al. with two modifications. Mineralization stage and impaction status were determined for all third molars. Statistical measures were calculated at stages C–H in the male and female gender for both impacted and non-impacted third molars. It was ascertained that the mean ages with impacted third molars at stages C–H were 0.02–1.42 years higher in males and 0.04–1.52 years higher in females than those with non-impacted third molars, but statistical differences were only found at stages C, D, and E in males and stages D and E in females. The probabilities of being under 14, 16, or 18 years of age with non-impacted third molars were all higher than those with impacted third molars. The results prove that impacted third molars show significant slower mineralization than non-impacted ones at stages D and E in both males and females of northwestern Chinese population. It is recommended to consider the influence of impaction on the rate of third molar mineralization for dental age estimation. 相似文献
19.
Determination of the stage of ossification of the medial clavicular epiphysis is a crucial part of forensic age estimation
when evaluating living subjects over 18 years of age. In the present study, we comparatively assessed conventional radiographs
and computed tomography (CT) scans of sternoclavicular joints used to perform forensic age assessments in 57 individuals undergoing
criminal proceedings. With CT, it was possible to determine the ossification stage of all clavicles studied. In the case of
conventional radiography, reliable assessment of ossification stage was not possible in 15 out of 114 clavicles studied due
to the superimposition of other structures. Regarding agreement between the methods, both radiography and CT produced identical
staging results in 97 out of 99 clavicular epiphyses. In two cases, however, ossification was classified as stage 2 by CT
and as stage 3 by conventional radiography. Regarding stages 4 and 5, both methods produced identical staging results in all
cases. In forensic age estimation practice, it is necessary that conventional radiographic reference studies be used for ossification
stage classification by conventional radiography and that CT reference studies be used for ossification stage classification
by CT. Further studies in dead bodies of known age are required to issue a recommendation as to whether conventional radiography
using obtained in three planes or CT is the method of choice for the assessment of clavicular ossification. 相似文献
20.
The clavicle plays an important role for forensic age estimation in living individuals, particularly with regard to the age of majority. The present prospective study aims to evaluate the age-dependent ossification process of the medial clavicular epiphysis in order to establish the clavicular sub-stages introduced in 2010 as well as the advantages and possibilities of thin-slice computed tomography (CT). For this purpose, 0.6 mm thin-slice CT scans of sternoclavicular joints of 572 bodies aged between 10 and 40 years were evaluated by means of two complementary classification systems: a five-stage system and a sub-staging system for the main stages 2 and 3. Assessment was possible in 493 cases. The results for stages 4 and 5 are in line with previous studies that found the ages of 21 years and 26 years, respectively, as minimum ages for these stages. Sub-stage 3c was first found at the age of 19 years in both sexes, thereby corroborating the value of this sub-stage as to statements about the age of majority. In comparison to other CT studies, stage 3a was first observed ~1 year earlier (16.4 years in males and 15.5 years in females). Stage 2c only occurred in 3 cases. In conclusion, the data corroborate the significance of diagnosing sub-stages as well as the value of thin-slice CT. For forensic practice, the concomitant and complementary use of both classification systems applied in this study can be recommended. 相似文献
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