COPD患者自我感受负担与抑郁状况调查及相关性分析

目的研究慢性阻塞性肺疾病(Chronic obstructive pulmonary disease,COPD)患者自我感受负担及抑郁情况,分析其影响因素。方法纳入南通市第一人民医院2015年5月至2016年2月期间收治的126例COPD患者,采用老年抑郁量表(Geriatric depression scale,GDS)以及自我感受负担量表(Self-perceived burden scale for cancer patients,SPBS-CP)对患者进行评估,采用多因素回归方程对患者一般资料进行分析,观察可能影响患者自我感受负担及抑郁的因素。结果患者年龄、病程、文化程度、婚姻状况、医疗付费情况、合并症以及呼吸困难程度资料对比有统计学差异(P0.05)。将上述有差异资料带入多因素回归方程计算分析发现,年龄、病程、文化程度、婚姻状况、合并症以及呼吸困难程度是影响患者自我感受负担的因素;而文化程度、婚姻状况、医疗付费情况、合并症以及呼吸困难程度是影响患者抑郁的因素。结论慢性呼吸系统疾病患者由于病程长、经济负担重等多种原因,导致患者容易出现自我感受负担以及抑郁状况。其中年龄、病程、文化程度、婚姻状况、合并症以及呼吸困难程度是影响患者抑郁状况及自我感受负担的重要因素,临床上需要针对性采取相应措施。     

结构性心理干预对肺癌患者自我感受负担及心理和谐的影响

目的探讨结构性心理干预对肺癌患者自我感受负担及心理和谐的影响。方法统计分析2011年3月至2014年10月我院收治的肺癌患者90例的临床资料。结果研究组患者干预前后的SPBS评分、SCCS评分差值均显著高于对照组(P<0.05)。结论结构性心理干预能够显著减轻肺癌患者的自我感受负担,有效提高患者的心理和谐。     

数字化故事叙述对卵巢癌化疗患者自我感受负担、配偶照顾负担及预期性悲伤的影响

目的 探究数字化故事叙述应用于卵巢癌化疗患者的效果及对配偶预期性悲伤、自我感受负担、配偶照顾负担的影响。方法 选取我科114例卵巢癌化疗患者,根据随机数字表法分组。对照组57例给予常规干预,观察组57例给予实施数字化故事叙述,对比两组患者的效果、副作用、自我感受负担、配偶照顾负担及配偶预期性悲伤。结果 两组患者干预后总有效率、不良反应发生率无统计学意义的差异（P>0.05）;干预后观察组自我感受负担量表（SPBS）、照顾者负担量表（ZBI）、预期性悲伤量表（AGS）各项评分均低于对照组（P<0.05）。结论 数字化故事叙述对卵巢癌化疗患者干预,可有效缓解患者配偶照护负担和预期性悲伤,降低自我感受负担。     

颅脑损伤伴骨盆骨折患者自我感受负担与正念水平的相关性

目的 探讨颅脑损伤伴骨盆骨折患者自我感受负担与正念水平的相关性,指导患者心理状态的调节,以改善预后情况.方法 选取2019-02—2020-02郑州市第九人民医院88例颅脑损伤伴骨盆骨折患者为研究对象,观察所有患者术后3个月的自我感受负担[通过自我感受负担量表(SPBS)评估]与正念水平[通过正念注意觉知量表(MAAS...     

中青年脑卒中患者自我感受负担与社会支持的相关性研究

<正>自我感受负担(self-perceived burden,SPB)是指由于经济、照顾、情感等方面原因,患者普遍存在的拖累家庭、成为别人负担的心理感受[1],高发于伴有肢体残疾的患者[2]。这种感受可引起患者抑郁、内疚、甚至自杀等强烈的负性情绪[3],影响其生活质量和治疗效果。脑卒中是严重威胁人类健康的疾病,近2/3脑卒中存活者遗留瘫痪、失语等不同程度的残疾[4]。脑卒中具有年轻化趋势,越来越多的中青年罹患脑卒中[5]。中青年是人生的关     

老年恶性肿瘤住院患者抑郁状况调查

目的:了解老年恶性肿瘤住院患者抑郁状况及影响因素。方法:采用抑郁自评量表(SDS)及相关因素调查表对老年恶性肿瘤住院患者(200例)及老年良性疾病住院患者(150例)进行对照调查分析。结果:老年恶性肿瘤住院患者的抑郁发生率为62.5%,SDS均分(52.0±10.4)分,显著高于老年良性疾病住院患者26.7%和(44.9±7.7)分(P均<0.01)。结论:老年恶性肿瘤患者抑郁发生率较高,抑郁情绪明显。     

老年脑卒中后抑郁及相关影响因素分析

目的　了解老年脑卒中后抑郁 (PSD)的发生率及与性别、文化程度、病变部位、病灶数目、致残程度的关系 ,对日常生活能力恢复的影响。方法　采用老年抑郁量表对 96例脑卒中患者进行评定 ,分为抑郁组和非抑郁组进行分析比较。结果　共有 44例患者有抑郁症状 ,总发生率为 45 83 % ,女性患者、文化水平偏低、病变部位在左半球及多个病灶者发生率高 ,致残程度与PSD呈正相关。结论　老年PSD发生率高 ,是多种因素共同作用的结果 ,直接影响病人的生存质量及功能恢复。     

加速康复理念下认知行为干预对缺血性脑卒中共病糖尿病失眠患者睡眠质量及自我感受负担的影响

目的 探讨基于加速康复理念的认知行为干预对缺血性脑卒中共病糖尿病失眠患者睡眠质量和自我感受负担的影响。方法 将2022-11—12郑州大学附属郑州中心医院治疗的缺血性脑卒中共病糖尿病的失眠患者80例随机分为对照组和试验组各40例。试验组实施认知行为干预,对照组实施常规护理干预。干预1个月后观察2组患者睡眠质量和自我感受负担水平。结果 2组患者干预前的PSQI及SPBS评分比较差异无统计学意义（P>0.05）;干预后2组患者的PSQI及SPBS评分比较差异均有统计学意义（P<0.05）。干预后对照组患者的PSQI及SPBS评分与干预前比较差异均无统计学意义（P>0.05）,试验组患者的PSQI及SPBS评分与干预前比较差异均有统计学意义（P<0.05）。结论 基于加速康复理念的认知行为干预可改善缺血性脑卒中共病糖尿病失眠患者的睡眠质量,降低其自我感受负担,对临床治疗具有重要意义。     

老年白内障患者疾病不确定感与其焦虑、抑郁及病情的关系

目的 探讨老年白内障患者疾病不确定感与其焦虑、抑郁及病情特点的相关性.方法 选择2019年1月～2020年1月75例老年白内障患者为研究对象,评估疾病不确定感量表(MUIS),采用医院焦虑抑郁自评量表(HADS)评估患者的焦虑、抑郁情绪,调查患病侧、眼压、视力等病情特点,采用单因素分析以及多元逐步回归分析调查老年白内障...     

Quality of life in schizophrenic patients: Association with depressive symptoms

The objective of this study was to examine to what extent depressive symptoms are associated with reduced quality of life in schizophrenia by using a general population sample as control group. Patients with ICD-10 schizophrenia stabilized during hospitalization with antipsychotics were compared with a general population sample by use of self-reported scales for quality of life (the WHO Quality of Life Short Form, WHOQOL- BREF) and for depression (the Major Depression Inventory, MDI). Of the schizophrenic patients screened for ability to participate in the study, 40, or 71%, completed the two questionnaires as psychometrically valid as the control group. Within the group of schizophrenic patients, no association was seen with the types of antipsychotic medication prescribed (typical vs. atypical antipsychotics). Both in the group of schizophrenic patients and in the general population sample, those persons scoring on the MDI to have depressive symptoms had significant reduced quality of life. In conclusion, approximately 70% of the schizophrenic patients stabilized during hospitalization with antipsychotics are able to validly complete self-report scales measuring quality of life and depressive symptoms. In these patients, depressive symptoms, as in the general population, was found to have association with reduced quality of life.     

The burden of depressive symptoms in the long-term treatment of patients with schizophrenia

OBJECTIVE: To prospectively measure the link between depressive symptoms and functional outcomes in the long-term treatment of people with schizophrenia. METHODS: Data were drawn from a large, multi-site, 3-year, prospective, naturalistic, observational study, in which subjects with schizophrenia were assessed at enrollment and at 12-month intervals thereafter. Individuals who were "Depressed" (defined as a total score > or =16 on the Montgomery-Asberg Depression Rating Scale) at enrollment were compared to those "Non-depressed" on functional outcomes, using self-report measures, clinicians' ratings, and information from medical records. Statistical analyses included Generalized Estimation Equation and mixed regression analyses adjusted for individual characteristics. Longitudinal group comparisons across the 3-year study were augmented with a cross-sectional group comparison at enrollment. RESULTS: At enrollment, 39.4% (877/2228) of the participants were deemed Depressed. Across the 3-year study, the depressed cohort was significantly more likely than the Non-depressed to use relapse-related mental health services (emergency psychiatric services, sessions with psychiatrists); to be a safety concern (violent, arrested, victimized, suicidal); to have greater substance-related problems; and to report poorer life satisfaction, quality of life, mental functioning, family relationships, and medication adherence. Furthermore, changes in depressed status were associated with changes in functional outcomes. CONCLUSIONS: People with schizophrenia and concurrent depressive symptoms have poorer long-term functional outcomes compared to the Non-depressed. Their poorer quality of life, greater use of mental health services, and higher risk of involvement with law enforcement agencies underscore a need for special treatment interventions. Treatment of the non-psychotic dimensions of schizophrenia is a critical part of recovery.     

痴呆伴发抑郁症状的临床研究

目的　了解痴呆伴发抑郁症状的发生率及评估方法的适用性。方法　用单盲交叉设计 ,由不同职称的临床医生分别采用Hamilton抑郁量表 (HAMD)和老年抑郁量表 (GDS)对 36例符合《中国精神疾病分类方案与诊断标准》(CCMD 2 R)痴呆患者的抑郁症状进行评估。结果　HAMD评分为(18.80± 11.13) ,抑郁症状发生率为 4 1.7% ;GDS评分为 (12 .6 0± 5 .96 ) ,抑郁症状发生率为 36 .1%。HAMD条目中较常见的有能力减退 2 6例 (72 % )、精神性焦虑 2 3例 (6 4 % )、有罪感 19例 (5 3% )、抑郁 17例 (4 7% )、睡眠障碍 17例 (4 7% )。逐步多元回归分析表明 ,影响抑郁症状评定的因素有病情严重程度、病人受教育程度和GDS。结论　痴呆伴发抑郁症状较常见 ,评估时应注意患者的病情、教育程度。HAMD适用于对痴呆病人抑郁症状的评估     

Coping strategies,caregiving burden,and depressive symptoms of Taiwanese mothers of adolescents with autism spectrum disorder

Little research focuses on the caregiving experiences of Taiwanese mothers of adolescents with autism spectrum disorder (ASD). The effects of the caregiving burden and coping strategies on the depressive symptoms of 60 of these mothers were examined. The adolescents they cared for ranged from 10 to 19 years old (mean age: 14.7 years). Mothers completed self-report written questionnaires. Findings indicated that greater use of problem-focused rather than emotion-focused coping was generally associated with lower levels of caregiver burden and fewer depressive symptoms. Problem-focused coping acted as a buffer when caregiving burdens were high. Specifically, actively confronting, planning, and suppressing competing activities as coping strategies moderated the effect of the caregiving burden on the depressive symptoms of these mothers. This significant buffering effect reflected adaptation to the caregiving burden. Awareness of the effects of coping strategies on maternal well-being could serve as a valuable guide for practitioners.     

Childhood adversity and depressive symptoms following retirement in the Gazel cohort

BackgroundOnly a few studies have examined whether specific moderators may impact the magnitude of the relationship between retirement and depression. The aim of this study was to examine the potential moderating role of adverse childhood life events (ACLE) on changes in depressive symptoms following retirement in the GAZEL cohort.Methods9242 participants, followed up since 1989, completed the Center of Epidemiologic Studies Depression scale (CESD) every three years and were asked in 2004 to answer an ACLE questionnaire. Subjects were classed according to 6 clusters by Two-Step Cluster Analysis (no ACLE: cluster 1; increasing material deprivation: clusters 2 to 4; history of early separation: cluster 5 and history of conflicts or violence: cluster 6), and then stratified for sex. Analyses were based on general linear models with the CESD variation between, before and after retirement as dependent variable. All results were adjusted according to age, marital status, occupational status, alcohol consumption, self-rated health and CESD score before retirement.ResultsThe association between exposure to ACLE and changes in depressive symptoms following retirement was significant in both men (F = 6.929; p < 0.001; eta² = 0.005) and women (F = 6.890; p < 0.001; eta² = 0.016). Exposure to early separation or history of conflicts or violence during childhood was associated with less improvement in both men and women, whereas early exposure to material deprivation only affected results in men.ConclusionsPrograms aimed at facilitating retirement transition may focus on subjects at risk of not experiencing the expected benefits of retirement, which is the case for those with a history of ACLE.     

抗抑郁治疗在脑卒中功能恢复中的作用

目的 探讨脑血管意外伴抑郁症状患者应用抗抑郁药物治疗对其病程及预后的影响。方法 经CES-D筛选出伴抑郁症状的125例脑血管意外患者,随机分为两组。治疗组65名,非治疗组62名,两组在年龄,性别,神经功能缺损及CES-D评分等项目上无明显差异。治疗组予抗抑郁药物PROZAC20mgqd治疗,平均治疗时间为175±43.8天,一月及一年后再对两组进行CES-D及神经功能缺损的评定及比较。结果治疗组一月及一年后CES-D评分均有明显下降(p<0.001),神经功能恢复也明显好于非治疗组(P<0.01)。结论 脑血管意外伴抑郁症状者给予抗抑郁治疗对其病情改善和预后均有好处。     

氟西汀治疗卒中后抑郁症的对照研究

目的 观察抗抑郁剂氟西汀对卒中后抑郁及神经功能康复的影响。方法 随机将72例卒中患者分为治疗组和对照组,在治疗前和治疗后4周、8周分别进行汉密尔顿抑郁量表(HAMD)和爱丁堡-斯堪的纳维亚卒中量表(MESSS)评分。结果 与对照组相比,治疗组HAMD评分和MESSS评分的减分率均较高(P<0.05)。结论 氟西汀可明显改善卒中后抑郁程度并能促进神经功能康复。     

Early cognitive impairment predicts long-term depressive symptoms and quality of life after stroke

OBJECTIVE: The aim of the present study was to examine the predictive value of cognitive impairment in the acute phase after stroke as a risk factor for long-term (six to ten months after stroke) depressive symptoms (DS) and a reduced quality of life (QOL), independent of demographic and neurological predictors. METHODS: We evaluated 143 patients within the first 3 weeks post-stroke. Predictor variables included domain-specific cognitive function, demographic data, vascular risk factors, lesion characteristics, and clinical factors. Predictor variables associated with long-term DS (Montgomery Asberg Depression Rating Scale >or=7) and QOL (Stroke-Specific Quality of Life Scale) were identified with multiple logistic and linear regression. RESULTS: Long-term DS were independently predicted by cognitive impairment at baseline, DS at baseline, female sex, diabetes mellitus, and previous TIA(s). Cognitive impairment, increasing age, and functional dependence predicted a reduced QOL, whereas hypercholesterolaemia predicted a better QOL. Among all cognitive disorders, unilateral neglect was the greatest risk factor for DS after 6 months, whereas a disorder in visual perception and construction affected QOL the most. CONCLUSIONS: Cognitive impairment and vascular risk factors are important predictors of long-term DS and QOL after stroke. The prognostic value of cognition suggests a reactive component in the development or continuation of long-term DS.