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1.
We report herein the case of a 69-year-old man who underwent laparoscopic adrenalectomy for a solitary adrenal metastasis
10 months after a left lower lobectomy for T2N1M0 lung cancer. A 30×20 mm tumor was found in the left adrenal gland, and dissected
using an ultrasonically activated scalpel. Histological examination revealed metastatic squamous cell carcinoma. The patient
recovered uneventfully and his condition is now stable 18 months after the second operation, with no evidence of local recurrence
or metastatic disease. Although laparoscopic resection for malignant adrenal tumors is still controversial, we consider that
laparoscopic adrenalectomy may be an optional treatment for metastatic adrenal tumors, provided the tumor is solitary, small
in size, and well-localized. To our knowledge, only 14 cases of laparoscopic adrenalectomy for malignant tumors have been
reported to date; however, this is the first case of successful laparoscopic adrenalectomy for a metastasis from lung cancer. 相似文献
2.
Takanobu Utsumi Hiroyoshi Suzuki Kazuyoshi Nakamura Woojin Kim Shuichi Kamijima Yusuke Awa Kazuhiro Araki Naoki Nihei Yukio Naya Tomohiko Ichikawa 《International journal of urology》2008,15(12):1077-1079
Renal cell carcinoma (RCC) is capable of metastasizing to several organs. Synchronous isolated contralateral adrenal metastasis of the primary RCC is, however, very rare. Herein we report a case of RCC with a huge solitary metastasis to the contralateral adrenal gland that was surgically treated. We scheduled nephrectomy for the left primary RCC and adrenalectomy for the right adrenal tumor. However, at surgery we found a huge right adrenal tumor that had invaded the right kidney, right renal vein, and inferior vena cava. Therefore right nephrectomy was performed simultaneously with resection and reconstruction of the inferior vena cava. Pathological findings demonstrated that the left renal tumor and right adrenal tumor had the same histology. Although the patient required hemodialysis, he remains well at six months postoperatively. So far, there have been only two cases of a solitary contralateral metastatic adrenal tumor that was larger than the primary RCC, thus the present case is the third one. 相似文献
3.
Successful combined resection of carcinoma of the esophagus and adrenal metastasis: Report of a case
Yutaka Yoshizumi Yoshihisa Morisaki Hiroshi Koike Hiroshi Shibata Renpei Yanagawa Yoshiaki Sugiura Susumu Tanaka 《Surgery today》1997,27(4):330-333
We report herein the case of a 56-year-old man who underwent successful combined resection of carcinoma of the esophagus and an adrenal metastasis. The patient presented with carcinoma of the thoracic esophagus, and an adrenal tumor was incidentally detected by computed tomography(CT). Complete removal of the carcinoma was accomplished along with a combined resection of the thoracic esophagus and left adrenal gland. Surgery was followed by the administration of anticancer chemotherapeutic agents. He is currently doing well with a grade 1 performance status and no signs of recurrence 22 months after his operation. To our knowledge, no previous report of the successful simultaneous resection of esophageal carcinoma and an adrenal metastasis has been documented in the literature. 相似文献
4.
We report a case of pharyngeal metastasis of hepatocellular carcinoma (HCC). Any oral cavity involvement of HCC, especially
pharyngeal metastasis, is extremely rare. The resected specimen contained a pedunculated polypoid lesion and histological
examination revealed an epithelial tumor with a trabecular growth pattern, covered with intact squamous mucosa. Immunohistochemical
studies were positive for hepatocyte-specific antigen and α-fetoprotein. At the time of writing, the patient, a 73-year-old
man, was alive but with multiple recurrent lesions in the remnant liver, 1 year after resection of the pharyngeal metastasis.
Oral metastases should be treated surgically or endoscopically if possible for the symptomatic relief of oral discomfort,
pain, and bleeding; however, the prognosis is generally poor. 相似文献
5.
Surgical treatment of a solitary pancreatic metastasis from renal cell carcinoma: Report of a case 总被引:2,自引:0,他引:2
Kazuhiko Jingu Kazuo Watanabe Hiroshi Yamamoto Yoshihiro Fujita Ichiro Honda Satoshi Watanabe Matsuo Nagata Katsumi Sugimoto Yoshiyuki Watanabe 《Surgery today》1998,28(1):91-94
(Received for publication on June 20, 1996; accepted on Jan. 7, 1997) 相似文献
6.
Contralateral adrenal metastasis of renal cell carcinoma: treatment,outcome and a review 总被引:4,自引:0,他引:4
OBJECTIVE: To report the surgical treatment of patients with renal cell carcinoma (RCC) metastatic to the contralateral adrenal gland and compare our experience with previous reports, as such metastases are found in 2.5% of patients with metastatic RCC at autopsy, and the role of resecting metastatic RCC at this site is not well defined. PATIENTS AND METHODS: We retrospectively identified 11 patients who had surgery for metastatic RCC to the contralateral adrenal gland between October 1978 and April 2001. The patients' medical records were reviewed for clinical, surgical and pathological features, and the patients' outcome. RESULTS: The mean (median, range) age of the patients at primary nephrectomy was 60.9 (64, 43-79) years; all had clear cell (conventional) RCC. Synchronous contralateral adrenal metastasis occurred in two patients. The mean (median, range) time to contralateral adrenal metastasis after primary nephrectomy for the remaining nine patients was 5.2 (6.1, 0.8-9.2) years. All patients were treated with adrenalectomy; there were no perioperative complications or mortality. Seven patients died from RCC at a mean (median, range) of 3.9 (3.7, 0.2-10) years after adrenalectomy for contralateral adrenal metastasis; one died from other causes at 3.4 years, one from an unknown cause at 1.7 years and two were still alive at the last follow-up. CONCLUSIONS: The surgical resection of contralateral adrenal metastasis from RCC is safe; although most patients died from RCC, survival may be prolonged in individual patients. Hence, in the era of cytoreductive surgery, the removal of solitary contralateral adrenal metastasis seems to be indicated. 相似文献
7.
Antonelli A Cozzoli A Simeone C Zani D Zanotelli T Portesi E Cosciani Cunico S 《BJU international》2006,97(3):505-508
OBJECTIVE: To report, in a retrospective study, the diagnostic problems and oncological results of surgery in patients with either synchronous or metachronous adrenal metastasis, which are uncommon in renal cancer, at 2-10% of patients. PATIENTS AND METHODS: Of 1179 patients treated for renal cancer between 1987 and 2003, 914 had renal surgery with concomitant ipsilateral adrenalectomy (routinely in 875 and for abnormal findings on computed tomography, CT, in 39) and 15 contralateral adrenalectomy (all after suspicious findings on CT). During the follow-up after renal surgery, another 14 patients had adrenalectomy for CT evidence of an abnormal adrenal gland, contralateral to the previous renal tumour in 12 and bilaterally in two. RESULTS: Of 914 ipsilateral adrenal glands removed during renal surgery, 854 (93.5%) were normal on pathological examination, 28 (3%) had a benign pathology, six (0.8%) were directly infiltrated by the tumour and 26 (2.7%) were metastatic. For both benign and metastatic ipsilateral adrenal pathology, CT had sensitivity, specificity and positive/negative predictive values of 47%, 99%, 73% and 96%, respectively. Of 29 contralateral glands removed because of suspicious CT findings (15 at diagnosis of renal cancer, 14 during the follow-up) there was no abnormality in one (3.4%), a benign pathology in seven (24%) and a metastasis in 21 (72%). Thus there were 32 synchronous (incidence 2.7%; ipsilateral to the renal tumour in 24, contralateral in six and bilateral in two), and 13 metachronous adrenal metastases (incidence 1.0%; contralateral in 11 and bilateral in two). The metachronous metastases were diagnosed at a mean (range) interval of 30.6 (8-73) months after renal surgery. No ipsilateral adrenal metastases were discovered at diagnosis or during the follow-up in the 382 patients with an organ-confined renal tumour of <4 cm in diameter. Twenty-seven patients with an isolated adrenal metastasis (synchronous in 14, metachronous in 13) had statistically significantly (P < 0.001) better survival than the 18 (all synchronous) with multiple sites of metastatic disease. In particular, there was long-term survival (mean 83 months) in 10 patients with an isolated adrenal metastasis. CONCLUSION: Sparing the ipsilateral adrenal is advisable only for organ-confined renal tumours of <4 cm in diameter; clinical local staging of renal cancer is the best predictor of the risk of adrenal metastasis. Conversely, CT had good diagnostic ability for the contralateral adrenal gland, especially during the follow-up. Some patients with isolated adrenal metastasis could be treated by metastasectomy, with long-term survival free of disease and confirming that, even if in a few and unselectable patients, removing all the neoplastic bulk can be curative. Nevertheless, the high rate of relapse underlines the need for an effective systemic therapy, and more so for widespread metastatic disease that currently cannot be cured. 相似文献
8.
Sakumoto N Inafuku S Shimoji H Nomura K Honma K Kawabata T Ohta M Kuniyoshi M Ishikawa K Genka K 《Surgery today》2000,30(8):744-746
A case of endobronchial metastasis from renal cell carcinoma developing 5 years after a right nephrectomy in a 63-year-old
man is reported. Bronchoscopic examination performed after the patient presented with hemoptysis showed a polypoid tumor obstructing
the entrance to the left upper bronchus. A snare was introduced through a bronchofiberscope to remove the endobronchial tumor,
following which his atelectasis improved remarkably and his hemoptysis resolved. No side effects were observed. Electrosurgical
snaring proved useful as palliative treatment to relieve bronchial obstruction due to an endobronchial metastasis in this
patient.
Received: April 5, 1999 / Accepted: March 24, 2000 相似文献
9.
Seigou Nishida Akira Tanimura Satoko Takasaki Sakae Nagaoka Mikio Fukueda Shinichi Ikeda Kenichi Matsuo Motoichi Akao Masaharu Tokunaga 《Surgery today》1995,25(5):455-457
This report describes the case of a 48-year-old woman found to have a leiomyoma of the left adrenal gland after presenting with anemia and hypertension. An upper gastrointestinal series revealed a mass in the posterior region of the body that distorted the stomach. A computed tomography (CT) scan showed a well-circumscribed mass with a high-density outline in the left adrenal gland, and magnetic resonance imaging (MRI) revealed a homogeneous mass. Multiple catheter samplings of vena cava blood revealed a slight elevation of epinephrine and norepinephrine in the left adrenal vein and the left renal vein. Thus, asymptomatic pheochromocytoma of the left adrenal gland was highly suspected as a preoperative diagnosis and a left adrenalectomy was performed. However, histologic examination subsequently revealed findings suggestive of leiomyoma of the adrenal gland, which was confirmed by electron microscopy. The patient's postoperative course was uneventful and she has remained free from any further symptoms. 相似文献
10.
Wakasugi M Ueshima S Akamatsu H Tori M Oshita M Tsujimoto M Nishida T 《International journal of surgery case reports》2012,3(9):455-459
INTRODUCTIONThe incidence of metastasis of hepatocellular carcinoma (HCC) to the gallbladder is low. Here, we report a case of HCC with metastasis to the gallbladder and discuss the pattern of spread and the treatment.PRESENTATION OF CASEA 74-year-old man was diagnosed with advanced hepatocellular carcinoma. Computed tomography and magnetic resonance imaging demonstrated a tumor in the right lobe of the liver with a thrombus in the bifurcation of the portal vein. Because intraoperative ultrasonography showed portal vein tumor thrombosis from the main tumor reaching the umbilical portion, we performed only a cholecystectomy for the elimination of postoperative cholecystitis. Pathological examination showed gallbladder vein tumor thrombosis from poorly differentiated hepatocellular carcinoma.DISCUSSIONA preoperative diagnosis of metastatic HCC to the gallbladder is difficult because there are no specific findings in the imaging tests. Cancer cells in the liver were thought to migrate to the gallbladder via the connection between the portal system and the cholecystic veins, and grow in the lumen of the veins in our case. The survival rate, in all reported cases including the present case, was increased in patients who underwent radical resection, compared to patients who underwent palliative surgery.CONCLUSIONThe resection of metastatic HCC to the gallbladder might appear to prolong survival. 相似文献
11.
Renal cell carcinoma with solitary synchronous pancreaticoduodenal and metachronous periprostatic metastases: Report of a case 总被引:1,自引:0,他引:1
(Received for publication on Jan. 19, 1998; accepted on July 7, 1998) 相似文献
12.
Tsukioka T Nishiyama N Iwata T Nagano K Izumi N Mizuguchi S Morita R Inoue K Suehiro S 《General thoracic and cardiovascular surgery》2007,55(11):455-460
Objective Although some beneficial effects of surgical treatments for pulmonary or hepatic metastases from colorectal carcinoma have
been reported, identifying candidates for these aggressive surgical procedures is controversial. In this study, patients with
pulmonary metastases from colorectal carcinoma, particularly those with pulmonary and hepatic metastases, were retrospectively
analyzed.
Methods Forty-six patients who had undergone complete resection for pulmonary metastases from colorectal carcinoma were retrospectively
analyzed.
Results The median follow-up period after pulmonary resection was 26 months, and the 5-year postoperative survival rate was 34%. The
5- and 10-year survival rates of patients with pulmonary metastasis alone, metachronous pulmonary metastasis after liver metastasis,
and synchronous metastasis to the liver and lung were 75%, 75%, and 25% and 25%, 38%, and 0%, respectively, when calculated
from the time of primary colorectal resection (P < 0.01). Patients with synchronous metastases had a poorer prognosis than did the patients in the other two groups.
Conclusions Surgical treatments for patients with pulmonary metastasis alone or metachronous metastasis can provide a beneficial outcome.
Patients with synchronous metastasis have a poor prognosis, and effective pre- and postoperative systemic treatments should
be considered to prolong their survival. 相似文献
13.
Fumio Kawaguchi Koonosuke Nakada Hiroaki Kitagawa Teruhiro Fujioka Yoshitaka Kim Tomotake Enami Mikio Kuwabara Munechika Wakisaka Noboru Yamate Hiroshi Chihara Masayuki Takagi 《Surgery today》1993,23(6):546-550
A male infant with bilateral adrenal neuroblastoma found by mass-screening is herein reported. The patient presented with almost equal-sized tumors, each remaining confined to the respective adrenal gland without crossing the midline. No other tumorous lesion was evident. The two adrenal tumors had similar histologic features and appeared to have grown concurrently. Such simultaneous occurrence of primary adrenal neuroblastoma is unusual, and appears to reflect the multicentric origin of this tumor. 相似文献
14.
SISTO PERDONÀ RICCARDO AUTORINO LUIGI GALLO MARCO DE SIO LUIGI MARRA LUIGI CLAUDIO CORRADO CARACÒ RENATO FRANCO FLAVIO FAZZIOLI ANTONIO GALLO 《International journal of urology》2005,12(4):401-404
Solitary metastases to the small bones and/or to the soft tissue of the hands and feet (acrometastases) are rare. We report a case of renal cell carcinoma (RCC) with big toe metastasis revealed before the primary tumor became apparent. The best treatment for a single metastasis is always surgical excision, regardless of the lesion being synchronous or metachronous. The biological behavior of metastatic RCC is unpredictable and only early diagnosis and treatment may favorably affect patient survival. Thus, metastatic RCC should be included in the differential diagnosis of all enlarging cutaneous nodules, wherever they develop. 相似文献
15.
Kazunari Okada Yang Il Kim Kimihiro Nakashima Izuru Tada Takanori Yoshida Michio Kobayashi Shigeo Yokoyama 《Surgery today》1993,23(7):626-631
A case of small fibrolamellar hepatocellular carcinoma (HCC) coexistent with a HCC of common type is herein reported. A 56-year-old man was diagnosed as having multi-nodular type HCC with liver cirrhosis. The serum alpha-fetoprotein (AFP) level was slightly increased. The patient underwent a partial caudate lobectomy and lateral segmentectomy. Histologically, both resected tumors were small HCCs measuring less than 2 cm in diameter. One was a fibrolamellar type located in the caudate lobe, while the other was the common type in the lateral segment of the liver. Positive immunohistochemical staining for AFP was observed in the tumor cells of the HCC of common type but was not observed in the fibrolamellar HCC. We also reviewed previously reported cases of fibrolamellar HCC in Japan, and discussed the clinicopathologic implications of this disease. 相似文献
16.
Eiji Hinoshita Hisashi Nakahashi Kenzo Wakasugi Satoshi Kaneko Motoharu Hamatake Keizo Sugimachi 《Surgery today》1999,29(8):799-802
Duodenal metastasis from primary lung cancer is extremely rare. It rarely shows any symptoms, and the prognosis for this condition
is poor. We herein describe the case of a 46-year-old woman with primary lung cancer who underwent a left upper lobectomy.
Severe anemia was observed about 20 days after lobectomy. Gastroduodenoscopy showed duodenal metastasis. Simultaneously, brain
metastasis was also detected using magnetic resonance imaging. The patient underwent a local resection of the duodenum and
a tumor resection of the brain. Postoperative irradiation of the brain metastases and systemic chemotherapy of the lung metastases
were performed, and complete remission occurred. However, abdominal lymph node metastasis recurred, and the patient died 1
year after the lobectomy. 相似文献
17.
18.
Arai H Rino Y Yamanaka S Yukawa N Wada N Kato H Yanagimachi M Goto H Oshiro H Yamanaka S Inayama Y Lee J Masuda M 《Surgery today》2008,38(10):965-969
Adrenocortical carcinoma (ACC) in childhood is rare: in 2002, only three new cases were reported in Japan. Although there is no established therapeutic management system, margin-free complete surgical excision of the tumor is very important to a satisfactory outcome. We report a case of ACC with bilateral pulmonary metastasis in a 10-year-old boy. Preoperative chest computed tomography (CT) showed pulmonary metastasis with near-water density. The patient was treated successfully with complete surgical resection of the primary tumor and adjuvant chemotherapy, including mitotane. After bilateral lung surgery for the metastatic lesions, the plasma dehydroepiandrosterone sulfate level became negative. 相似文献
19.
Masayuki Kawai Kiyomi Sahashi Hiroshi Yamase Yoshihiko Kishida Kei Sumida Ken-ichi Kawamura 《Surgery today》1998,28(9):974-978
(Received for publication on Feb. 14, 1997; accepted on Sept. 2, 1997) 相似文献
20.
Management of adrenal metastasis from hepatocellular carcinoma 总被引:9,自引:0,他引:9
Momoi H Shimahara Y Terajima H Iimuro Y Yamamoto N Yamamoto Y Ikai I Yamaoka Y 《Surgery today》2002,32(12):1035-1041
Purpose: Although the adrenal gland is a common site of extrahepatic metastasis from hepatocellular carcinoma (HCC), there are no
definitive guidelines for the treatment of adrenal metastasis. This study examines the effectiveness of various treatments
for this disease.
Methods: We retrospectively analyzed 20 patients treated for adrenal metastasis of HCC by adrenalectomy (n = 13), transarterial chemoembolization (TACE), or percutaneous ethanol injection therapy (PEIT) (n = 7).
Results: There were no significant differences in cumulative survival rates between patients given adrenalectomy and those given TACE
or PEIT, either after completing treatment for primary HCC or after the first treatment for adrenal metastasis. Six of seven
patients with tumor thrombi in the inferior vena cava (IVC) from adrenal metastasis underwent adrenalectomy combined with
intracaval thrombectomy, five of whom survived for more than 1 year after surgery, and two of whom are still alive without
any recurrence more than 3 years after surgery. PEIT showed good results for small adrenal metastasis.
Conclusion: These findings suggest that therapeutic modalities should be chosen according to the clinical features of each individual,
including the size of the metastatic tumor, whether there is invasion into the IVC, the function of the remaining liver, and
the existence of intra- and/or nonadrenal extrahepatic lesions. Furthermore, intracaval tumor thrombectomy could be indicated
for patients with IVC thrombus if they are suitable candidates for surgery.
Received: July 9, 2001 / Accepted: July 2, 2002
Reprint requests to: Y. Shimahara 相似文献