To explore the anti-aging effects of mild-warming moxibustion on Bcl−2 and PKC expression in peripheral blood and general symptoms in elderly people.
Methods
A total of 61 elderly people and 30 non-elderly people were enrolled. The total effective rate of mild-warming moxibustion was assessed by symptom scores, and Bcl−2 and PKC expression in peripheral blood was detected by flow cytometry.
Results
The total effective rate in the mild-warming moxibustion group was significantly higher than in the blank control group (P<0.01). Bcl−2 and PKC expression rates in peripheral blood in the blank control group were lower than in the normal control group (P<0.01), but higher after mild-warming moxibustion (P<0.01).
Conclusion
The anti-aging effects of mild-warming moxibustion may be due to increased Bcl−2 and PKC expression in peripheral blood in aged people. 相似文献
ObjectiveTo observe the clinical efficacy of grain-shaped moxibustion in reinforcing healthy qi and dispelling pathogen and to explore the possible mechanisms of grain-shaped moxibustion in improving immune function of patients through determining the expression level of IL-12 in peripheral blood of patients.MethodsSeventy patients undergoing chemotherapy due to deficiency of both qi and blood type of malignant tumor in the departments of traditional Chinese medicine and oncology in Nanjing Drum Tower Hospital Affiliated to Nanjing University Medical School from January 2014 to January 2015 were randomly divided into a chemotherapy group (group A) and a chemotherapy combined with grain-shaped moxibustion group (group B) by sortition, 35 cases in each one. Patients in both groups received chemotherapy, while patients in group B also received grain-shaped moxibustionat on bilateral Zúsānlľ ( ST 36), which was performed once daily, 7 cones every time, for a total of continuous 20 days. Before and after treatment, the expression level of IL-12 in peripheral blood of patients was determined using ELISA method.ResultsAfter chemotherapy, the expression level of IL-12 in patients was significantly lower than that before treatment. After two courses of adjuvant therapy of grain-shaped moxibustion, the expression level of IL-12 in chemotherapy patients slightly increased and the difference was statistically significant (P<0.05).ConclusionGrain-shaped moxibustion can increase the expression of IL-12 in peripheral blood of patients, promote the T cell-mediated immune response and achieve immunoregulation and anti-tumor effects. 相似文献
To explore the mechanism of moxibustion for people in sub-health status.
Methods
Thirty-nine young and middle-aged sub-health volunteers were enrolled, including 13 males and 26 females. Mild moxibustion was adopted, and Shénquè ( CV 8), Guānyuán ( CV 4), Zúsānl? ( ST 36, bilateral), Píshū ( BL 20, bilateral) and Shènshū ( BL 23, bilateral) were selected. The moxibustion was performed once every other day, 20 min at each time, and moxibustion for ten times was needed. The changes in morphology, flow velocity and pefiloop of nailfold microcirculation were detected by adopting microcirculation detector before moxibustion, after moxibustion for three times, six times, ten times, and on the 15th day after moxibustion, respectively.
Results
After moxibustion, the abnormal blood capillary morphology of microcirculation gradually turned into normal pattern along with the increase of the number of times of moxibustion, according to the comparison of the number of capillary loop, the diameter of input limb, the diameter of output limb/the diameter of input limb, flow pattern integral, pefiloop integral and total integral with those before moxibustion, the differences were all statistically significant (all P<0.01).
Conclusion
Moxibustion changs the microcirculation of nailfold of body, improves the blood flow pattern, makes the pefiloop status clear, accelerats the blood flow and increases the microcirculation perfusion amount, thus regulating the sub-health status of human body. 相似文献
ObjectiveTo evaluate the lipid-regulating effect of crude-herb moxibustion on rats with dyslipidemia.MethodsFifty-four Sprague–Dawley rats were randomly divided into six groups with nine rats each. Control group rats were fed a normal diet, and bilateral acu-point Fenglong (equivalent to ST40 in humans) on the hind legs were covered with a placebo (general mucilage) for 2 hours each day. Model group rats were fed a high-lipid diet for 2 weeks. Therapy group rats were fed a high-lipid diet for 2 weeks and then administered crude-herb moxibustion at ST40 for 2 hours each day for the next 2 weeks. Prevention group rats were administered crude-herb moxibustion 2 hours a day for 2 weeks and then fed a high-lipid diet for the subsequent 2 weeks. Prevention/Therapy group rats were each administered crude-herb moxibustion at ST40 for 2 hours each day for 2 weeks, followed by a high-lipid diet for the next 2 weeks, and then crude-herb moxibustion again at ST40 for another 2 weeks. Simvastatin group rats were fed a high-lipid diet for 2 weeks and then treated with simvastatin for the next 2 weeks. Blood lipids, hepatosomatic indices (HSIs) and epididymal fat pad weights of all rats were examined.ResultsCompared with the Model group, levels of total cholesterol (TC), glycerinate, low-density lipoprotein cholesterol (LDL-C) and very low-density lipoprotein cholesterol (VLDL-C) in plasma collected from the Therapy group, the Prevention/Therapy group, and the Simvastatin group were decreased. Moreover, compared with the Model group, HSIs in Therapy group rats were also decreased following administration of crude-herb moxibustion, but TC, TG, HDL-C, LDL-C, and VLDL-C levels in the Prevention group were higher than those in the Model group.ConclusionThe results reveal that blood lipids and HSIs appear to be modulated by the effect of crude-herb moxibustion and suggest therapeutic strategies for the treatment of dyslipidemia. 相似文献
