Solid-Pseudopapillary Tumor of the Pancreas： One Case Report and Literatures Review

Introduction Solid-pseudopapillary tumor(SPT)is a very mre primary neoplasm of the pancreas.Franz first described it in 1959.It iS usually seen in young females.In spite of possible histological findings of malignancy,SPPT typically shows a benign clinical course and a low malignant potential.The pathogenesis of these tumors iS still controversial.It has been suggested that it might originate from ductal and acinar pancreatic cells,endocrine cells or pluripotential stem cells.     

Hepatoid Carcinoma of the Pancreas： a Case Report

Case Report A 37-year old female patient suffering from an upper abdominal pain,accompanied by recent emaciation and anorexia that resulted from a two-month epigastric lump,visited a doctor in our hospital in January,2007.Physical examination of the patient by palpation identified a 10.0×8.0 cm2 lump from the xiphoid process above the middle and superior abdomen.The lesion was hard with a rough surface,the upper boundary unsharp,and the inferior and right boundary clearly apparent.The pain at the site of the lump was only apparent with touching at that site.     

Solid Pseudopapillary Tumor of the Pancreas:a Case Report

Case Report Solid pseudopapillary tumors(SPT)of the pancreas are considered to be a rare low-grade malignancy that mainly appears in young women.It accounts for less than 1%of all pancreatic neoplasms and is pathologically distinctive from other types of pancreatic cancers.Curative resection is the optimal choice for SPT and the 5-year survival rate of SPT is about 95%.Here we report a case of a young girl who presented with this rare pancreatic tumor.     

Solid Pseudopapilllary Tumor of the Pancreas： a Case Report

Solid pseudopapillary tumors （SPT） to be a rare low-grade malignancy of the pancreas are considered that mainly appears in young women. It accounts for less than 1% of all pancreatic neoplasms and is pathologically distinctive from other types of pancreatic cancers. Curative resection is the optimal choice for SPT and the 5-year survival rate of SPT is about 95%. Here we report a case of a young girl who presented with this rare pancreatic tumor.     

IgE Myeloma： the First Report of Chinese Case and a Review of the Literature

To report a case of IgE myeloma and to compare its clinical features with those reported in the literature. Methods: M-component in serum and urine was determined using celluloseacetate membrane electrophoresis, immunofixation electrophoresis and quantification of immunoglobulins. Immunohistochemistry was performed to detect the expression of IgE and its light chain. Results: A monoclonal peak was detected by cellulose-acetate membrane electrophoresis. The monoclonal band showed on immunofixation electrophoresis the following reactive patterns: positive for A antisera and negative for κ, IgG, IgA, IgM and IgD antisera. The serum immunoglobulin concentrations were: IgG 21.6 g/L, IgA1.2 g/L, IgM 2.64 g/L, κ 7.49 g/L, λ 16.0 g/L, κ/A 0.47. The results of immunohistochemistry showed cytoplasmic expression of IgE immunoglobulin and A light chain in the tumor tissue. Conclusion: This is the first case of IgE multiple myeloma reported in China.     

Mixed Medullary-follicular Thyroid Carcinoma： Report of a Case and Review of the Literarture

Mixed medullary-follicular carcinomas （MMFCs） are tumors of the thyroid that display morphological and immunohistochemical features of both medullary and follicular neoplasms. These tumors are rare and less than 40 cases have been described in the literature since the early 1980s The term medullary-follicular thyroid carcinoma denotes a tumor which exhibits the features of a medullary carcinoma and shows positive expression of calcitonin on immunohistochemistry. It is a follicular-derived thyroid carcinoma and is positive for thyroglobulin expression within the same tumor. Most reported cases have lymph node involvement at the time of diagnosis. In cases having disease progression, distant metastases develop in the lung, liver, mediastinum and bone. We report a case of a male patient with mixed medullary-follicular thyroid carcinoma and a review of the literature.     

Primary Renal Angiosarcoma： One Case Report and Literatures Review

Introduction Angiosarcomas are rare highly malignant neoplasm that make up less than 2% of all soft-tissue sarcomas.Only 40 renal cases     

Mucin-Producing Urothelial-Type Adenocarcinoma of the Prostate （a Case Report and Review of the Literature）

OBJECTIVE To report clinical and pathologic findings of one case of mucin-producing urothelial-type adenocarcinoma of the prostate, and to discuss the diagnosis and prognosis of this disease. METHODS The patient was a 60-year-old man who had an 8-month history of urinary frequency and dysuria culminating in an aggravating condition for 10-days. Laboratory results were tPSA 3.0 and fPSA 0.4. An ultrasound and digital rectal exam showed no abnormal findings, so he was diagnosed as having benign prostatic hyperplasia, and underwent a transurethral prostate resection. RESULTS The findings during the operation resembled benign prostatic hyperplasia (BPH), whereas the pathological exam showed that the pro-static construction was deranged in the tumor infiltrating region, with many mucin lakes and signet ring cell in the cancer tissue. Immunohisto-chemical staining revealed that the cancer tissue was negative for prostate-specific antigen (PSA) and postive for carcinoembryonic antigen (CEA). Final diagnosis: mucin-producing urothelial-type adenocarcinoma of the prostate. After 50 Gy radiotherapy, the patient was free of recurrent signs and metastasis up to 8 months after operation. CONCLUSION Mucin-producing urothelial-type adenocarcinoma of the prostate is extremely rare. Its differential diagnosis mainly includes conventional prostatic adenocarcinoma with mucin production and secondary adenocarcinoma. The diagnosis and treatment of this disease should be further investigated.     

Leiomyosarcoma of Inferior Vena Cava: Report of 7 Cases and Literature Review

Leiomyosarcoma of inferior vena cave (IVC) is an ex-tremely rare primary malignant tumor, no more than 200cases of leiomyosarcoma of IVC were reported in publi-cations as single case or as small series up to date. Inthis report, 7 cases of primary leiomyosarcoma of IVC werepresented. The diagnosis and treatment of leiomyosarcomaof IVC were also reviewed.Materials and methodsGeneral conditionIn this report, 7 cases of leiomyosarcoma of IVC con-sisting of 1 male and 6 females with an age ranging from29 to 61 were presented. Two cases underwent laparotomywith the diagnosis of carcinoma of pancreas or primary     

Rhabdoid Meningioma in a Child： Report of a Case and Literatures Review

Meningiomas occur in 1%-4% of primary intracranial tumors in the pediatric group, and is increasing in incidence with age. Some authors have reported that meningioma is more prevalent among adult males, but there is no gender prevalence. The accepted origin of meningiomas is from the arachnoid ceils lining the meninges, or the choroid plexuses. Since Beckwith and Palmer introduced the term ＇rhabdoid tumor＇ in 1978 in reference to a subgroup of childhood malignant renal tumors, many tumors with a rhabdoid morphology have been reported in various sites, including the central nervous system. In 1998 Kepes et al.     

Primary Angiosarcoma of the Womb： A Case Report

Case Report A 35 year old patient was admitted to the hospital on March 27th, 2005 because of profuse leukorrhea for 3 months and progressive ab- dominal pain for half a month. The leukorrhea, which started for no apparent reason, contained streaks of blo…     

Primary Renal Malignant Fibrous Histiocytoma Four-Case Report and Review of the Literature

OBJECTIVE To evaluate the diagnosis and treatment for primary renal malignant fibrous histiocytoma, a rare tumor arising from the kidney.METHODS The clinical and pathological data from 4 cases of malignant fibrous histiocytoma of the kidney detected in our hospital are described.One case of special interest involved a giant cell subtype, the first to be reported in the oncology literature. The clinicopathologic features and prognostic factors of this tumor were analysed and summarized after reviewing 55 documented cases in the English and Chinese literature.RESULTS A palpable mass (71.2%), emaciation (54.2%) and pain (54,2%) were common manifestations in renal MFH, Of all the cases, 51 were identified as a storiform-pleomorphic subtype by pathologists. Inconsideration of all the prognosis related factors, the residual tumor and high TNM stage predicted a shortened survival duration, but the symptom of a fever served as a better prognostic factor.CONCLUSION Malignant fibrous histiocytoma which arises from the kidney is a rare pathologic type, and possesses a high tendency towards local recurrence and distant metastasis. Despite the poor prognosis, early detection and radical surgery can prolong survival in selected cases.     

Leiomyosarcoma of Inferior Vena Cava: Report of 7 Cases and Literature Review

Leiomyosarcoma of inferior vena cave (IVC) is an ex- Resultstremely rare primary malignant tumor, no more than 200cases of leiomyosarcoma of IVC were reported in publi- Pathological featurescations as single case or as small series up to date[1]. In The 7 cases of IVC leiomyosarcoma were con?rmed bythis report, 7 cases of primary leiomyosarcoma of IVC were the postoperative pathology. The IVC was encompassedpresented. The diagnosis and treatment of leiomyosarcoma by…     

Non-Functioning Pancreatic Neuroendocrine Tumors—A Case Report and Review of Literature

Purpose

Neuroendocrine tumors of pancreas (PNET) are rare pancreatic neoplasms comprising 1–2% of all pancreatic tumors. The overall prognosis and long-term survival for PNET patients is far better than for patients with exocrine pancreatic cancer. PNETs are classified as functional or nonfunctional based on the presence or absence of a specific clinical syndrome associated with hormone oversecretion.

Methods

We present the case of a 36-year-old female with epigastric and right upper quadrant abdominal pain for 3 months associated with decreased appetite, early satiety and a 20-lb weight loss. On examination, she was cachectic with hepatomegaly.

Results

Laboratory assays showed elevated liver and pancreatic enzymes. On computed tomography (CT) scan of the abdomen and pelvis, there was a low-attenuation mass in the distal pancreatic tail measuring 4.7?×?2.4 cm with multiple liver masses, omental implants, left ovarian mass, and a small amount of ascites. CT-guided liver biopsy on pathology was consistent with a well-differentiated pancreatic neuroendocrine carcinoma with metastasis to the liver. Assays for biomarkers of pancreatic neuroendocrine tumors showed an elevated chromogranin A with normal to non-specific elevations of the rest.

Conclusions

The patient and her family declined palliative chemoembolization of the liver lesions or palliative chemotherapy and desired home hospice. We describe here the presentation and course of the case as well as a literature review of PNET with particular emphasis on nonfunctioning PNETs.     

Synchronous Hepatocellular Carcinoma and Gastric Carcinoma—A Case Report with Review of the Literature

Purpose

The study was designed to investigate the clinicopathological correlations, relationship to apoptotic index, and prognostic significance of estrogen receptor beta expression in colorectal carcinoma.

Methods

The study was carried out on 40 patients with newly diagnosed colorectal cancer. The patients?? data were collected prospectively and the 2?years overall survival was the endpoint. Estrogen receptor beta expression was assessed by immunohistochemistry. Apoptotic body index was calculated by counting apoptotic cells using the modified TUNEL assay.

Results

Estrogen receptor beta positivity was detected in 65% of colorectal cancer cases, while estrogen receptor alpha positivity was found in only 7% of cases. The rate of estrogen receptor beta immunoreactivity was significantly higher in low-grade colorectal tumors. The median apoptotic index in estrogen receptor beta positive cases was significantly higher than in estrogen receptor beta negative cases (6% versus 3%; p?=?0.01). The median overall survival was higher in estrogen receptor beta positive cases (22 versus 18?months); however, the difference was not statistically significant.

Conclusions

The study results reinforce the importance of the estrogen receptor beta rather than the estrogen receptor alpha in colorectal cancer. Lack of estrogen receptor beta expression is associated with loss of differentiation and decreased apoptosis. Future studies should include validation of estrogen receptor beta as a prognostic marker and exploration of its role as a target in the management of colorectal cancer.     

Local Recurrence of Low-Grade Myofibroblastic Sarcoma of the Chest Wall： Report of a Case and Literatures Review

Myofibroblastic sarcoma, composed primarily of myofibroblast, is a rare malignant tumor. Low-grade myofibroblastic sarcoma （LGMS） has been defined properly as a distinct entity in the 2002 WHO classification of soft tissue tumors. Primary sarcoma of the chest wall is also a rare disease. This article describes a case of locally recurrent LGMS of the chest wall.     

Primary Retroperitoneal Müllerian Adenocarcinoma: A Case Report and Literature Review

Primary retroperitoneal müllerian adenocarcinoma (PRMA) is an extremely rare clinical entity. We report the case of a 54-year-old woman who presented with a mass in the right lower retroperitoneum, identified during an ultrasound exam. Computed tomography confirmed a retroperitoneal mass measuring 11 cm. The patient underwent laparotomy and the mass was completely excised. The histopathological exam revealed PRMA.Key words: Malignant mixed müllerian tumor, Primary retroperitoneal müllerian adenocarcinoma, Gynecological malignancy