C-Arm Computed Tomography Compared With Positron Emission Tomography/Computed Tomography for Treatment Planning Before Radioembolization

The purpose of this study was to determine whether rotational C-arm computed tomography (CT) allows visualization of liver metastases and adds relevant information for radioembolization (RE) treatment planning. Technetium angiography, together with C-arm CT, was performed in 47 patients to determine the feasibility for RE. C-arm CT images were compared with positron emission tomography (PET)/CT images for the detection of liver tumors. The images were also rated according one of the following three categories: (1) images that provide no additional information compared with DSA alone; (2) images that do provide additional information compared with DSA; and (2) images that had an impact on eligibility determination for and planning of the RE procedure. In all patients, 283 FDG-positive liver lesions were detected by PET. In venous contrast-phase CT, 221 (78.1%) and 15 (5.3%) of these lesions were either hypodense or hyperdense, respectively. In C-arm CT, 103 (36.4%) liver lesions were not detectable because they were outside of either the field of view or the contrast-enhanced liver segment. Another 25 (8.8%) and 98 (34.6%) of the liver lesions were either hyperdense or presented primarily as hypodense lesions with a rim enhancement, respectively. With PET/CT as the standard of reference, venous CT and C-arm CT failed to detect 47 (16.6%) and 57 (20.1%) of all liver lesions, respectively. For RE planning, C-arm CT provided no further information, provide some additional information, or had an impact on the procedure in 20 (42.5%), 15 (31.9%) and 12 (25.6%) of patients, respectively. We conclude that C-arm CT may add decisive information in patients scheduled for RE.     

Quantitative Single-Photon Emission Computed Tomography/Computed Tomography for Glomerular Filtration Rate Measurement

Purpose

We propose a quantitative Tc-99m diethylenetriaminepentaacetic acid (DTPA) single-photon emission computed tomography/computed tomography (SPECT/CT) for glomerular filtration rate (GFR) measurement.

Methods

Quantitative SPECT/CT data obtained at 2–3 min post-Tc-99m DTPA injection (370 MBq) were used to determine % injected doses (%IDs) for individual kidneys. The reproducibility of %ID measurement was tested and compared with planar scintigraphy. Cr-51 ethylenediaminetetraacetic acid (EDTA) GFR was used as reference standard. Nine young volunteers, representing normal GFR, and ten older volunteers, reflecting impaired GFR, were enrolled. The established GFR equation derived from these volunteers was applied to 19 renal tumor patients post-partial nephrectomy.

Results

At 2?3 min, %ID was most reproducible with the highest intraclass correlation (ICC) (0.9379) and lowest % coefficient of variation (CV) (6.5259%), which were more reliable than the ICC (0.9368) and %CV (6.7689%) of planar scintigraphy. Cr-51 EDTA GFR (93.16 ± 24.81 ml/min) correlated significantly with %ID (7.66 ± 2.15%, r = 0.7906, p = 0.0001), yielding an equation: Cr-51 EDTA GFR (ml/min) = (%ID × 9.1462) + 23.0653. This equation revealed significant decreases in total and nephrectomized kidney GFR (p = 0.0012 and p < 0.0001, respectively) from preoperative to 3-month postoperative measurements.

Conclusions

Quantitative Tc-99m DTPA SPECT/CT produces reliable and clinically applicable %ID estimates that translate to the GFR of individual kidneys.

     

脊髓纵裂畸形的CT诊断

本文报告了８例脊髓纵裂畸形的ＣＴ表现，８例中骨性间隔６例，纤维性间隔１例，无间隔者１例。合并畸形有椎管内脂肪瘤１例，皮样囊肿１例，皮下脂肪瘤１例，皮下脂肪堆积１例，椎体或附近发育异常６例。ＣＴ不仅能１００％显示纵裂中的骨性间隔，而且可显示存在的合并畸形，因此它是一种很有价值的检查方法。     

胸壁病变的计算机X线摄影和CT检查

目的：探讨胸壁病变的计算机Ｘ线摄影（ＣＲ）和ＣＴ表现及其诊断价值,提高对胸壁病变的认识。材料和方法：回顾分析经手术病理、穿刺细胞学检查或临床随访资料证实的３９例ＣＲ和ＣＴ资料。结果：感染组１２例中（包括化脓性感染４例,胸壁结核８例）,ＣＲ准确诊断４例,ＣＴ诊断１１例;软组织肿瘤组１６例中（包括脂肪瘤７例,纤维肉瘤４例,血管瘤、神经纤维瘤、恶性纤维组织细胞瘤、侵袭性纤维瘤病和脂肪肉瘤各１例）,ＣＲ准确诊断３例,ＣＴ诊断１４例;骨肿瘤和肿瘤样病变组１１例中（包括骨纤维异常增殖症７例,软骨瘤２例,多发性骨髓瘤和骨嗜酸性肉芽肿各１例）,ＣＲ准确诊断８例,ＣＴ诊断１０例。结论：ＣＲ简便,能诊断大多数胸壁骨性病变。ＣＴ对各种胸壁病变尤其是软组织病变的诊断较ＣＲ明显优越,对鉴别胸壁肿瘤的良恶性有肯定作用,但仍有一定限制。     

阴茎癌的CT诊断价值

目的 探讨阴茎癌的CT表现及其诊断价值.资料与方法 回顾性分析12例经手术病理证实的阴茎癌患者的CT表现.结果 CT表现为阴茎头不规则分叶状或菜花状软组织肿块,密度均匀,肿瘤直径1-9 cm不等,平均3.5 cm.增强扫描动脉期病变呈中度强化,此期显示肿瘤侵犯深度更加清楚,7例显示阴茎海绵体受累,1例阴茎根部皮肤受累.8例淋巴结转移,其中双侧转移5例,单侧转移3例(右侧2例,左侧1例).12例患者中均未发现盆腔淋巴结及其他脏器转移.结论 CT可显示阴茎癌原发肿瘤的大小、形态及对阴茎侵犯深度,同时可显示淋巴结及远处转移情况,为临床制定治疗方案提供参考.