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1.
Cases of leiomyosarcoma in the head and neck are very rare with only four reports of a leiomyosarcoma originating in the hypopharynx. A rare case of leiomyosarcoma of the hypopharynx is described. A 62-year-old woman, who had experienced slight difficulty of swallowing and hoarseness, visited our hospital. A smooth-surfaced tumor was found extending from the postcricoid to an area in the left pyriform sinus, and the vocal cord on the left side was fixed. Imaging studies, including FDG-PET CT imaging showed the tumor in the postcricoid, but no distinguishable distant metastases. A total laryngectomy with a left-lobe thyroidectomy was performed. Since no metastases of the regional lymph nodes were found by imaging, a neck dissection was not performed. Dense infiltration by spindle-shaped and/or round-like cells was observed histologically as the predominant growth pattern. In immunohistochemical staining, the tumor was positive for desmin and muscle actin, while it was negative for myoglobin, myogenin, cytokeratin, and S-100 protein. Electron microscopic examination did not show Z banding and sarcomeres. Those features lead to the diagnosis of a leiomyosarcoma. No recurrence has been found at 1 year after the surgery. Immunohistochemical staining and electron microscopic examination are essential for a definite diagnosis of leiomyosarcoma. 相似文献
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Primary leiomyosarcoma of the parotid gland is an extremely rare neoplasm. We here describe the case of a 78-year-old male patient presenting with such a tumor. Five years after surgical treatment, the patient is alive and recurrence-free. To our knowledge, our case represents just the sixth case of primary leiomyosarcoma of the parotid gland reported in the English literature. The clinical features of these cases are summarized. 相似文献
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Leiomyosarcoma of the larynx is an extremely rare neoplasm; only about 50 cases have been reported in the English-language literature. We report a new case of laryngeal leiomyosarcoma in a 65-year-old man. The metastatic work-up was negative, and the patient underwent total laryngectomy. He remained disease-free 12 months postoperatively. 相似文献
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Ashok Gupta Parvinderjit Singh Kohli 《Indian journal of otolaryngology and head and neck surgery》2007,59(4):374-376
Leiomyosarcoma of larynx is a rare tumor. We report a case of 70 year old male who had presented to our department with respiratory
distress and stridor. Patient’s emergency was managed with tracheostomy with subsequent total laryngectomy and post-op external
radiotherapy. One year into follow-up, patient is tumor free. 相似文献
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Fusconi M Magliulo G Della Rocca C Marcotullio D Suriano M de Vincentiis M 《American journal of otolaryngology》2002,23(2):108-111
Leiomyosarcoma of the paranasal sinuses is uncommon and has an aggressive clinical behavior. Only 28 cases have been described in the literature, and, of these, only 3 patients treated with surgery had a disease-free survival. In this report, we describe the clinical history of a 57-year-old woman with a leiomyosarcoma of the paranasal sinuses successfully treated with a combination of surgery, radiation therapy, and chemotherapy. We obtained a total response with ifosfamide, doxorubicin, dacarbazine, and epirubicin. This case report emphasizes the possibility of treating this aggressive tumor with chemotherapy in accordance with the same therapy used in the treatment of uterine leiomyosarcomas. 相似文献
7.
M J Shapiro 《The Laryngoscope》1970,80(5):777-787
Basal cell nevus syndrome is a rare hereditary multiple-system progressive disorder which was first reported as such by Binkley and Johnson in 1951.1 Since then, retrospectively and de novo, over 150 cases have been reported. Reviews2,3,4 have tried to define the clinical features which constitute the syndrome, but so many anomalies have been described that for the sake of clarity, I have eliminated all but the more salient features. 相似文献
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Peripheral ameloblastoma is a rare, benign, extraosseous neoplasm of the odontogenic epithelium. We report a case of peripheral ameloblastoma, detail our surgical therapy and review important elements in the pathological diagnosis and treatment of this unusual neoplasm. 相似文献
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Patrocínio JA Patrocínio LG Martins LP Silva AM 《Anales otorrinolaringológicos ibero-americanos》2002,29(3):229-235
The leiomyosarcoma of the larynx is a neoplasm extremely odd, only 46 cases are reported in the literature. We present a case seen in our Department. A male patient, 39-year-old, smoker, snoring and respiratory insufficient, who showed a whitish mass, 2.5 cm, round, steady on the right vocal fold. Urgent tracheostomy was performed but afterwards the patient refused new surgery. Biopsy revealed a malignant tumour of fusiform cells, validating as diagnostic through immunohistochemical analysis, a leiomyosarcoma case. Five months later the patient was seen again and a total laryngectomy performed. Eleven months after surgery the patient is alive and no signs of recurrence detected. In this paper diagnosis and treatment of leiomyosarcoma is discussed. 相似文献
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Leiomyosarcoma of the larynx is an extremely rare entity. This tumor is aggressive and is associated with dismal treatment results. We present a case of leiomyosarcoma of the larynx treated with surgery and postoperative radiotherapy. In this article we also discuss laryngeal leiomyosarcoma's clinical manifestations, associated diagnostic dilemmas, and optimal management, as well as a review of the literature. 相似文献
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Kutluhan A Yalçıner G Bozdemir K Ozdemir E Tarlak B Bilgen AS 《Kulak Burun Bogaz Ihtis Derg》2012,22(3):160-163
The patient was admitted to our clinic with the complaint of swelling in his left post-auricular region. The medical history revealed that he underwent thyroid surgery eight years ago and the specimen was reported as papillary thyroid carcinoma. Following required analyses, total thyroidectomy and biopsy from mastoid region were performed. Total thyroidectomy specimen was proved thyroid papillary microcarcinomas at five foci of the thyroid gland, while biopsy samples obtained from the mastoid region were reported as metastatic papillary thyroid carcinoma. The patient underwent radioactive iodine, followed by radiotherapy. In this article, we present a 61-year-old male patient with papillary thyroid carcinoma metastatic to the temporooccipital region, accompanied by multiple cranial nerve paralysis. 相似文献
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Basaloid squamous cell carcinoma (BSCC) is a recently recognized high-grade tumor with a propensity for nodal as well as systemic metastasis and can arise from different anatomic locations. The differential diagnosis includes adenoid cystic carcinoma, small cell neuroendocrine carcinoma and squamous cell carcinoma. Monoclonal antibodies reactive with cytokeratin (34betaE12, AE3, pancytokeratin), as well as other cellular antigens (vimentin [VIM]; synaptophysin [SYNF]; chromogranin A [ChA]; neuron-specific enolase [NSE]; S-100, desmin, smooth-muscle actin [SMA]), were used in an immunoperoxidase method with paraffin-embedded tissue to phenotypically characterize a case with features of BSCC arising in the maxillary sinus. Neoplastic cells reacted with the high-molecular-weight cytokeratin antibody 34betaE12, as well as with other antikeratin antibodies, but failed to react with the antibodies VIM, desmin and SMA and showed variable immunoreactivity for NSE, SYNF and S-100. The staining pattern for NSE was diffuse and intense and reactivity for ChA was inconsistent. 相似文献
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Metastatic diseases of thyroid are rarely seen. For the patients who had previous malignancy in their history, metastatic lesions should not be ignored in the differential diagnosis of massive lesions in the thyroid gland, even the primary tumor was treated years ago. In this article, we present a case with lung adenocarcinoma which was metastatic to the thyroid gland. 相似文献
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Large intraosseous arteriovenous malformations (AVM) of the maxilla are rare lesions, which are probably hamartomas. We report a case of an 8-year-old child who presented with exsanguinating hemorrhage after an attempted dental biopsy. The management of dental intraosseous AVMs includes transarterial embolization and direct intralesional injection of liquid acrylic (NBCA). This approach avoids mutilating surgery and its sequelae in children. We present this case for its rarity and the intralesional use of acrylic glue in its management. 相似文献
19.
Esthesioneuroblastoma is a rare malignancy of olfactory neuroepithelium arising from sinonasal region. It has biologically an aggressive behavior. The tumor is characterised by common local recurrence, atypic distant metastasis and poor long-term prognosis. Cervical metastasis accounts for 20-30% of the patients. Late metastases are seen particularly six months or later following primary treatment. In this article, we present a 43-year-old female case with Kadish B stage esthesioneuroblastoma who underwent extracranial tumor resection and postoperative radiotherapy. Eleven years later (at 132 months) right neck cervical metastasis was occurred and we applied right functional neck dissection and adjuvant radiotherapy to treat. We also review the treatment of late neck metastasis in the light of the current literature data. 相似文献
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D Carles F Devars J Saurel L Traissac P Boudard 《Revue de laryngologie - otologie - rhinologie》1992,113(2):115-117
The authors report a new case of laryngeal leiomyosarcoma. The patient was a 43-year-old-man. The tumor extended to the left vocal cord, the paraglottic space and the deep layers of the left false vocal cord. Histologically, the lesion showed the typical pattern of a grade-3 leiomyosarcoma. Immunochemical studies revealed a strong positive staining with the actin smooth muscle antisera. A partial laryngectomy was performed. There was no evidence of recurrent or metastatic disease 10 months after surgery. 相似文献