国外皮肤病治疗速报

本文收集了２００１年５～９月部分国外皮肤病专业杂志皮肤病治疗方面的资料，综述如下。寻常疣Bhat等犤１犦用安慰剂对照开放试验方法观察了蚁酸点刺治疗１００例皮损主要位于手部的寻常疣的疗效（眼睑、唇和鼻孔部位除外）。方法：将病人平均分为治疗组和安慰剂组（用水）。清洗皮损后，将蚁酸或水滴在皮损上，用２４号注射针将蚁酸或水刺入皮损，共刺５～６次，以不出血为度。面部和儿童皮损不用针刺。隔日１次，直至皮损消退。结果：治疗后３个月，治疗组和安慰剂组分别有９２％和６％皮损消失，分别平均使用４．６０±２．４７次和１…     

国外皮肤病治疗速报

急、慢性荨麻疹Simons等犤１犦为了预防异位性皮炎的幼儿发生急性荨麻疹进行了一项前瞻性、随机、双盲、安慰剂对照的临床研究。方法：８１７例患异位性皮炎的幼儿被随机分配至西替利嗪治疗组和安慰剂对照组。其中３９９例接受西替利嗪治疗０．２５mg／kg，每天２次，３９６例接受安慰剂治疗。两种药物外观相似，均制成溶液早餐和晚餐滴入食物中同服，共１８个月。治疗结束后，仍在双盲的情况下随访６个月。治疗期间，幼儿的监护人将患儿的症状、事件和服药情况记录在卡片上，健康时每周记录一次，有症状时每天记录一次。在治疗前、治疗的…     

国外皮肤病治疗速报

病毒性皮肤病Bhat等[１]报道用８５％的甲酸点刺疗法治疗寻常疣就取得较好疗效。作者采用开放性、非随机、安慰剂对照的临床试验方法治疗了１００例寻常疣（男５５例，女４５例，年龄８～６１岁）。治疗组和对照组各５０例。方法：治疗前先用酒精消毒皮损局部，将８５％的甲酸或安慰剂（蒸馏水）滴到皮损上，然后用２４号针头点刺皮损５～６次，隔日治疗１次，直到皮损消失。每月随访１次，随访３个月。结果：治疗３～４周后，治疗组４６例痊愈（９２％），对照组３例痊愈（６％）。治疗组中有１２％的患者发生继发感染，经用抗生素治疗恢…     

国外皮肤病治疗速报

本文综述了１９９５年１１月～１９９６年５月部分国外期刊发表的皮肤病治疗方面的报道     

国外皮肤病治疗速报

国外皮肤病治疗速报本文综述了１９９３年１１月～１９９４年２月部分国外期刊发表的皮肤病治疗方面的报道。感染性皮肤病Ｂｅｉｓｓｅｒｔ［１］等采用β－干扰素成功治愈了一例播散性寻常疣患者。患者为男性，２９岁，双手反复出现多发性寻常疣１３年。曾用多种方法治疗...     

国外皮肤病治疗速报

国外皮肤病治疗速报本文综合了１９９３年４月～１９９３年９月部分国外文献关于皮肤病治疗方面的报道。感染性皮肤病病毒性皮肤病ＧｏｌｄｂｅｒｇＬＨ等［１］总结了口服无环鸟苷５年对防治生殖器复发性疱疹的疗效。病人（≥１８岁，孕妇除外）均无明显其它系统病变，共...     

国外皮肤病治疗速报

国外皮肤病治疗速报本文综合了１９９３年８月～１９９３年１１月部分国外期刊发表的皮肤病治疗方面的报道。银屑病焦油用于治疗银屑病已几个世纪了，尽管其应用广泛，几乎没有证据支持单纯应用焦油的临床效果。传统观点认为应用焦油的精制成分如煤焦油溶液和液体碳去污剂...     

国外皮肤病治疗速报

本文收集了 2000年 2月～ 6月国外部分期刊皮肤病治疗方面的文献,现综述如下。 皮肌炎 鹿田纯一郎 [1]等报道 1例 52岁女性,四肢及躯干皮肤硬化 4月,四肢近端肌力下降半月。肌电图显示：肌原性损害, CK、醛缩酶、 LDH显著升高,皮肤和肌肉病理分别示硬皮病、肌炎改变,确诊为系统性硬皮病与多发性肌炎重叠。给予泼尼松 40mg/d[1mg/(kg.d)]1周, CK由 5 000降到 1 000,以后症状无改善而将泼尼松加量至 60mg/d, 3周,症状仍无改善,而改用倍他米松 6mg/d, 2周后加用甲基泼尼松龙 1g/d, 6天后 CK降到 700,肌力仍无改善,加用硫唑…     

Evidence-based dermatologic out-patient treatment

Objective To determine the evidence base for routine therapeutic decisions in dermatologic out-patients. Design A retrospective review of a random sample of primary therapy and literature. Setting University hospital, dermatologic out-patient clinic in Copenhagen Material A random sample of the case notes from 115 out-patients. Method The evidence base of therapy prescribed when the diagnosis was ascertained was studied in literature searches in MEDLINE^® and EMBASE^®. Evidence was structured into primary evidence consisting of randomized controlled trials, and secondary evidence consisting of follow-up studies or the application of trial results between diseases with pathogenic or clinical similarities, e.g. atopic and seborrheic dermatitis. Results Randomized controlled trials could be found describing 38% (95% confidence interval: 30–47) of all treatments. Secondary evidence was found for 33%^24–41, while no evidence was found for 23%^16–31 of the given treatments. Conclusions Approximately three-quarters of dermatologic out-patient therapy is based on scientific evidence ranging from randomized controlled trials to logical deduction from analogous clinical situations. The proportion of evidence-based medicine in dermatologic therapy therefore appears to be comparable with that of internal medicine and may thus be above expectations.     

Capsaicin in the treatment of dermatologic disease

Capsaicin cream is the first of a class of neuropeptide active agents to be introduced into dermatologic therapy. Capsaicin's effects appear primarily related to its ability to deplete the neuropeptide substance P from local sensory terminals in the skin. The use of capsaicin cream in the treatment of postherpetic neuralgia and psoriasis is discussed. I believe that capsaicin and other neuropeptide active agents may become important therapeutic modalities for the dermatologist in the near future.     

Atraumatic wound dressing from the dermatologic viewpoint

We report on the method of atraumatic wound closure. The closure of the wound is achieved by resorbable intracutaneous suture and subsequent connection of the lips by means of textile adhesive plaster or tissue adhesive.