显微手术夹闭与血管栓塞术治疗脑动脉瘤的疗效分析

目的探讨显微手术夹闭与血管栓塞术治疗脑动脉瘤的疗效分析。方法选取2014年2月-2016年12月我院收治的20例脑动脉瘤患者,随机将其分为对照组10例与观察组10例,对照组患者给予血管栓塞术进行治疗,观察组患者给予显微手术夹闭治疗,对比两组患者临床疗效。结果观察组10例患者治疗总有效率显然高于对照组(P0.05);观察组患者各项指标明显低于对照组(P0.05)。结论临床中使用显微手术夹闭对脑动脉瘤患者进行治疗,效果更佳,且手术成本较低,值得推广。     

显微手术夹闭与血管栓塞术在脑动脉瘤治疗中的应用效果比较

目的 探究显微手术夹闭与血管栓塞术在脑动脉瘤治疗中的应用效果.方法 选取2013年1月至2020年12月盘锦市中心医院收治的120例脑动脉瘤患者作为研究对象,按照抛硬币法分为对照组与观察组,每组60例.对照组给予血管栓塞术治疗,观察组给予显微手术夹闭治疗,比较两组恢复时间、相关评分、并发症发生率及临床疗效.结果 两组治...     

显微手术夹闭与血管栓塞术治疗脑动脉瘤的疗效分析

目的:探讨显微手术夹闭与血管栓塞术治疗脑动脉瘤的疗效情况。方法:分析收治的45例脑动脉瘤患者的临床资料,依据治疗措施不同进行临床分组,显微手术夹闭组18例和血管栓塞术组27例。结果:显微手术夹闭组脑动脉瘤患者总有效率明显高于血管栓塞术组,差异有统计学意义(P<0.05)。结论:显微手术夹闭治疗脑动脉瘤的效果明显,预后水平较好,值得临床推广应用。     

显微夹闭术和血管介入术治疗大脑前动脉瘤出血的疗效对比

目的比较大脑前动脉瘤破裂患者早期行显微夹闭术与血管介入术的综合临床疗效。方法回顾性分析2001年1月至2016年12月在我院手术治疗的81例大脑前动脉瘤患者,依据治疗方法不同将其分为两组,其中对照组33例患者经血管内介入栓塞术治疗,观察组48例患者经显微手术方法治疗。比较两组的治疗总有效率、手术时间、手术中出血量、住院时间、并发症发生率及复发率。结果观察组的各项指标均优于对照组,差异有统计学意义(P0.05)。结论大脑前动脉瘤破裂出血的患者早期行显微手术夹闭治疗效果可靠,值得临床推广应用。     

不同方法治疗破裂脑动脉瘤的疗效分析

目的:分析不同方法治疗破裂脑动脉瘤的效果.方法:选取2017年1月至2020年1月收治的100例脑动脉瘤患者为研究对象,按治疗方法分为血管栓塞术组和显微手术夹闭组,各50例;血管栓塞组是采用介入的方法用弹簧圈将动脉瘤栓闭,显微夹闭组是采用翼点入路开颅将动脉瘤夹闭.对比两组患者临床手术效果、治疗有效率以及并发症发生率.结果:显微手术夹闭组手术时间为(180.55±9.17)min,血管栓塞组手术时间(76.48±7.35)min,显微手术夹闭组手术时间明显高于血管栓塞组.治疗后显微手术夹闭组手术时间、术中出血量、VAS评分以及术后恢复时间均与血管栓塞术组存在差异(P<0.05);显微手术夹闭组并发症发生率低于血管栓塞术组(χ2=4.162,P=0.041);治疗有效率方面,两组患者差异无统计学意义(χ2=0.126,P=0.722).结论:显微手术夹闭与血管栓塞术对破裂脑动脉瘤的治疗效果差异不大,血管栓塞术手术时间少于显微手术夹闭,但显微手术夹闭在并发症预防方面表现更佳,医生可根据患者病情特征选择最佳手术方式.     

显微手术夹闭与血管栓塞术治疗脑动脉瘤的疗效探讨

目的探讨对应用显微手术夹闭与血管栓塞术两种方式对患有脑动脉瘤的患者实施治疗的临床效果。方法抽取56例患有脑动脉瘤的患者,随机分为对照组和治疗组,平均每组28例。对照组患者接受血管栓塞术方式治疗;治疗组则是接受显微手术夹闭方式治疗。结果治疗组患者治疗有效率为89.3%,对照组为60.7%,两组差异有统计学意义(P<0.05);治疗组患者手术操作时间、术后恢复时间以及术中出血量等均较对照组发生明显降低(P<0.05);围手术期出现不良反应的患者人数明显少于对照组;术后动脉瘤病情再次复发率明显低于对照组。结论应用显微手术夹闭方式对患有脑动脉瘤的患者实施治疗的临床效果非常明显。     

开颅夹闭手术与血管栓塞介入术治疗脑动脉瘤破裂的效果对比

目的 比较开颅夹闭术与血管栓塞介入术治疗脑动脉瘤破裂的临床效果.方法 回顾性分析2017年6月—2020年1月于中山大学附属第三医院粤东医院神经外科接受治疗的60例脑动脉瘤破裂患者的临床资料,将采取血管栓塞介入术治疗的患者纳为观察组(32例),将采取开颅夹闭手术治疗的患者纳为对照组(28例).比较2组患者手术指标与术前...     

开颅夹闭手术与血管栓塞介入术治疗脑动脉瘤破裂的效果比较

目的:观察开颅夹闭手术与血管栓塞介入术治疗脑动脉瘤破裂效果及安全性。方法:选取脑动脉瘤破裂患者74例为研究对象,根据手术方式不同将其分为对照组和观察组,每组37例。对照组予开颅夹闭手术治疗,观察组予血管栓塞介入术治疗,比较两组患者的临床效果,手术时间、住院时间、血清基质金属蛋白酶-2(MMP-2)水平、红细胞计数及并发症发生情况。结果:两组脑动脉瘤破裂患者的治疗优良率和并发症发生率比较,差异无统计学意义(P>0.05);观察组手术时间、住院时间短于对照组,且术后MMP-2水平及红细胞计数低于对照组,差异均有统计学意义(P<0.05)。结论:在脑动脉瘤破裂的治疗中,开颅夹闭手术与血管栓塞介入术的临床疗效相近,并发症发生率相当,但血管栓塞介入术具有微创、术后恢复快等特点,有助于患者术后早日恢复。     

颅内多发动脉瘤的显微神经外科手术夹闭和血管内栓塞治疗的临床对比

目的分析颅内多发动脉瘤的显微神经外科手术夹闭和血管内栓塞治疗的效果。方法选取2015年1月至2016年8月我院收治的颅内多发动脉瘤患者17例,分析其临床表现,并根据影像学检查结果行显微神经外科手术夹闭和血管内栓塞治疗,同时回顾性分析治疗效果。结果术后痊愈13例,轻残2例,植物生存1例,死亡1例;术后行PSa检查显示瘤蒂夹闭满意、动脉瘤消失;术后出现2例脑积水,均行V-P分流术。结论显微神经外科手术夹闭和血管内栓塞治疗颅内多发动脉瘤的效果较好,但仍存在脑血管痉挛问题,须积极应对以改善预后。     

颅内动脉瘤显微手术及血管内栓塞治疗的比较研究

目的比较显微外科手术和血管内栓塞治疗颅内动脉瘤疗效和相关并发症。方法对62例64个颅内动脉瘤外科治疗,其中行显微手术瘤颈夹闭34例,血管内电解可脱性弹簧圈栓塞治疗28例;对两组疗效和并发症进行比较分析。结果显微手术组:33例成功夹闭瘤颈(其中2例分离瘤颈时动脉瘤破裂),1例合并脑内血肿在清除血肿后急性脑膨出未能显露动脉瘤;手术相关并发症4例,死亡2例。31例术后两周复查血管造影,动脉瘤完全夹闭83.9%(26/31)。血管内栓塞组:动脉瘤完全闭塞70.0%(21/30);血管内栓塞相关并发症2例,无死亡。结论显微手术和血管内栓塞是治疗颅内动脉瘤的有效方法,二者互有优缺点,相互补充。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.     

Possible Spread of adenovirus type 3 from poultry to humans ：indirect evidence from an outbreak in China

Objective:To explore the epidemiology and etiology for an outbreak of acute respiratory tract infection that occurred in one county of Jiangsu Province, China 2004. Methods: Only cases meeting the case definition were included in the study. We reviewed the medical records of the cases who were admitted to the local hospitals, interviewed cases by a standard questionnaire, and then described the epidemiotogic features and analyzed risk factors by means of a case-control study. We collected pharyngeal swab specimens and sent them to different laboratories for isolation and culture. The laboratory used different detection methods such as DIP, PCR, electron microscope examination and microneutralization assay, to identify and then type the positive specimens. Results:A total of 871 cases were reported during the period from April 18 to July 4,2004. The distribution of onset times presented two peaks, one in late May and another in middle June. The epidemic occurred mainly in the elementary and junior high schools in ten townships of one county, and the mean age of the cases was 12 years (range 7 months to 18 years). The course of the disease was acute, and was characterized by fever accompanied with sore throat and tonsillitis. The WBC count of cases was normal or elevated. The mean duration of illness was 5 days (range 2 to 12 days). No fatalities from illness were reported. A case-control study indicated that the possible risk factors were close contact with a case and/or poultry before onset and sharing of towels among members of the family. The typical CPE was observed through inoculating pharyngeal swab specimens into the HEP-2 cell cultures in different laboratories. An infection of adenovirus type 3 was verified by detecting positive specimens in different methods. Conclusion:This investigation demonstrated that the acute respiratory infection in cases was caused by adenovirus type 3. Cases occurred in over 70 schools in ten townships in 2004, and the route of transmission was possibly close contact with cases or droplet transmission.