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1.
目的:评价经皮闭合复位空心螺钉内固定治疗踝关节骨折的临床疗效与价值。方法:回顾分析2001年10月至2005年4月在C臂电视透视下采用经皮闭合复位空心螺钉内固定治疗踝关节骨折患者36例,其中单踝骨折11例,双踝骨折16例,三踝骨折9例,术后随访(6~30)个月,平均15个月。结果:36例患者均愈合良好,无感染及骨折不愈合病例,按Mazur的踝关节功能评分,优18例(50%),良14例(38.9%),可4例(11.1%),优良率达88.9%。结论:采用电视透视下经皮闭合复位空心螺钉内固定技术治疗踝关节骨折是一种有效的方法,符合微创原理,能获得满意疗效,适宜骨科临床应用。 相似文献
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目的分析空心螺钉经前踝内固定治疗后踝关节骨折的临床疗效。方法选择2008年10月-2013年6月收治的后踝骨折患者57例,均采用闭合复位空心螺钉经前踝内固定术治疗,并对其临床疗效进行评价。结果术后57例患者均获得6~36个月的随访,平均随访时间为18个月。骨折愈合时间8~12周,平均10周。依据美国AOFAS协会足踝评分系统对其临床疗效进行评估。57例患者得分为76~100分,平均96分,其中优54例(94.7%),良3例(5.3%),差0例,优良率为100%。结论闭合复位空心螺钉经前踝内固定治疗后踝关节骨折,具有创伤小、对周围血运破坏少,骨折愈合快,踝关节功能恢复好等优点,值得临床推广应用。 相似文献
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目的观察闭合复位空心螺钉经皮内固定治疗sandersII型跟骨骨折的临床疗效和安全性。方法采用克氏针撬拨复位空心螺钉经皮内固定治疗sandersII型跟骨骨折患者40例40足,男25例,女15例;年龄25~60岁,平均(38.5±13.6)岁。左侧骨折15例,右侧骨折25例。病程2~11d,平均(5.4±1.6)d。结果本组患者均获随访,随访时间12~24个月,平均(16.5±36)个月。手术时间30-45min,平均(385±76)min。术后40例患者的Bhler角和Gissane角均恢复正常。所有患者的骨折均在11周内愈合,未发生感染及螺钉松动等并发症。术后12个月随访时按照Maryiand足部功能评分标准评定,优28例、良9例、可3例,结论闭合复位空心螺钉经皮内固定治疗sandersII型跟骨骨折手术时间短、疗效满意、安全性高,值得临床推广应用。 相似文献
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目的:探讨闭合复位经皮空心螺钉内固定选择性治疗外踝骨折的手术方法及临床效果.方法:对采用闭合复位经皮空心拉力螺钉内固定治疗113例成人外踝骨折的临床资料进行回顾性分析.并采用X线片评估骨折愈合率和美国足踝骨科协会(AOFAS)推荐的足踝评分系统评估踝关节功能.结果:平均随访27个月,骨折愈合时间7~16周.按AOFAS足踝评分系统评分,平均94分;优107例,可6例,优良率93.8%.结论:闭合复位经皮空心螺钉内固定,是一种可用于治疗外踝骨折的微创术式,具有骨折愈合快、愈合率高、踝关节功能好等优点. 相似文献
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目的:探讨研究不同内固定方法治疗踝关节骨折的临床疗效。方法:将符合标准的94例踝关节骨折患者的临床资料,根据患者自身意愿分成闭合复位组(50例)和切开复位组(44例),闭合复位组患者给予闭合复位经皮空心螺钉内固定法治疗踝关节骨折,切开复位组患者给予传统切开复位内固定方法治疗踝关节骨折。结果:闭合复位组患者手术时间、术中出血量、骨折愈合时间以及负重功能锻炼时间均显著低于切开复位组(P0.05)。结论:采用闭合复位经皮空心螺钉内固定法治疗踝关节骨折具有更好的临床疗效,值得临床进行推广并进一步深入研究。 相似文献
6.
目的:探讨用闭合复位经皮空心螺钉内固定术治疗后踝骨骨折的临床效果。方法:对2011年4月~2014年4月期间我院收治的24例后踝骨骨折患者的临床资料进行回顾性研究。我院使用闭合复位经皮空心螺钉内固定术对这24例患者进行治疗。结果:这24例患者骨折部位愈合的时间在6~12周之间,平均愈合时间为7.5周。他们骨折部位愈合的优良率为95.8%。结论:用闭合复位经皮空心螺钉内固定术治疗后踝骨骨折疗效显著,可有效地缩短患者骨折部位愈合的时间。此疗法值得在临床上推广使用。 相似文献
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目的:探讨闭合复位经皮空心加压螺钉治疗股骨颈骨折的临床效果。方法:对12例股骨颈骨折采用闭合复位经皮空心加压螺钉内固定治疗。结果:12例均获随访(1~5)年,疗效参照沈侠评定标准:优8例,差2例。结论:闭合复位经皮空心加压螺钉治疗股骨颈骨折具有创伤小,操作简便,固定可靠、术后恢复快、骨折愈合率高、功能恢复好等优点,是一种治疗股骨颈骨折的有效方法。 相似文献
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目的对闭合复位及经皮空心螺钉内固定治疗胫骨平台骨折的临床效果进行分析,为临床治疗胫骨平台骨折提供参考依据。方法选取本院2008年05月-2010年05月收治的42例胫骨平台骨折患者,随机分为观察组(21例)与对照组(21例);观察组采取闭合复位及经皮空心螺钉内固定进行治疗,对照组采取开放性整复钢板内固定进行治疗。术后进行随访,评价两组患者的临床效果。结果经过6-20个月的随访,平均11个月,两组患者治疗总有效率比较差异有显著性(χ2=8.552,P〈0.05),观察组优于对照组。结论闭合复位及经皮空心螺钉内固定治疗胫骨平台骨折效果显著,对患者的创伤轻,患者恢复快,操作简便,值得临床推广应用。 相似文献
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Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD. 相似文献
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Jiageng Zhu Jun Li Ruipeng Ji Jianghao Su Mingshun Shen Zhigang Cao 《南京医科大学学报(自然科学版)》2007,21(2):125-128
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment. 相似文献
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Tao Ye * Zhi-quan Liu Jian-jun Mu Xi-han Fu Jun Yang Bao-lin Gao and Xiao-hong Zhang Department of Cardiology First Hospital of Xi'an Jiaotong University Xi'an Hanzhong Cardiovascular Institute Hanzhong 《中国医学科学杂志(英文版)》2004,19(4):248-251
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure. 相似文献
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目的:评价使用安心颗粒对急诊经皮冠状动脉介入术(PPCI)术后生活质量的影响.方法:将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组(术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次)和对照组(仅接受基础药物治疗).所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表(MIDAS)、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果:入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异(P>0.05);出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低(P<0.05);组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低(P<0.05).两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血(P>0.05).两组发生轻度血小板减少症的患者数比较无差异(P>0.05).结论:PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险. 相似文献
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Jingming Zhu Ningning Hui Xiuhong Jiang Huaxing Zhang Chengzhang Fu 《南京医科大学学报(自然科学版)》2007,21(6):386-389
Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P<0.01);the MAP decreased(P<0.01)and the HR increased drastically(P<0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients. 相似文献
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Objective:To investigate the gene expression of osteoprotegerin(OPG) and osteoclast differentiation factor(ODF) in the bone tissue of patients with hip fracture due to osteoporosis. Methods:OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers(over 50 years old) with hip fracture(Observer Group) and 30 cases of hip facture sufferers with no osteoporosis(Control group) were analyzed with the Semi-Quantitative RT-PCR method. Results:The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion:Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption. 相似文献
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The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas: report of 9 cases 总被引:1,自引:0,他引:1
Shaoqin Chen Shengquan Zou Qibao Dai Peisheng Huang Weihua Cai Hong Li 《南京医科大学学报(自然科学版)》2007,21(6):398-401
Objective:To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas(SPTP). Methods:Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin(HE) staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results:Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin(9/9 cases), AAT(9/9 cases), NSE(9/9 cases), ACT(7/9 cases), CK20(2/9 cases), CgA(1/9 cases), S-100(3/gcases), PR(4/gcases), Syn(3/9 cases) and CD56(5/9cases), negative in CEA and ER. Conclusion:SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype. 相似文献
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Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P. 相似文献
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Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine. 相似文献
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Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center. 相似文献