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Development and field testing of Teen Pocket PATH®, a mobile health application to improve medication adherence in adolescent solid organ recipients 下载免费PDF全文
Diana A. Shellmer Mary Amanda Dew George Mazariegos Annette DeVito Dabbs 《Pediatric transplantation》2016,20(1):130-140
Applying principles of user‐centered design, we iteratively developed and tested the prototype of TPP, an mHealth application to promote medication adherence and enhance communication about medication management between adolescents and primary caregivers. A purposive sample of seven adolescent solid organ transplant recipients who were ≥one yr post‐transplant and their primary caregivers participated. Participants completed up to three face‐to‐face laboratory usability sessions, a 6‐week field test, and a debriefing session. Primary caregivers participated in an additional usability telephone session. Participants completed usability and satisfaction measures. Sample included liver (n = 4), heart (n = 2), and lung (n = 1) recipients aged 11–18 yr (57% were female, 86% were Caucasian), and nine primary caregivers aged 42–61 yr (88.9% were parents, 88% were female, 88% were Caucasian). Ninety percent of the adolescents endorsed the graphs or logs of missed/late medication dosing as useful and 100% endorsed the remaining features (e.g., medication list, dose time reminders/warnings) as useful. All adolescents expressed interest in using TPP for monitoring medications and satisfaction with the automatic messaging between adolescent and caregiver versions of the application. Adolescents unanimously found TPP easy to use. TPP shows promise as an mHealth adherence tool. 相似文献
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13‐valent pneumococcal conjugate vaccine (PCV13) is immunogenic and safe in children 6‐17 years of age with sickle cell disease previously vaccinated with 23‐valent pneumococcal polysaccharide vaccine (PPSV23): Results of a phase 3 study 下载免费PDF全文
Mariane De Montalembert MD PhD Miguel R. Abboud MD Anne Fiquet MD Adlette Inati MD Jeffrey D. Lebensburger DO Normeen Kaddah MD Galila Mokhtar MD Antonio Piga MD Natasha Halasa MD MPH Baba Inusa MD David C. Rees FRCPCH Paul T. Heath FRCPCH Paul Telfer MD Catherine Driscoll MD Sami Al Hajjar MD Alberto Tozzi MD Qin Jiang MS Emilio A. Emini PhD William C. Gruber MD Alejandra Gurtman MD Daniel A. Scott MD 《Pediatric blood & cancer》2015,62(8):1427-1436
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Committed to work but vulnerable: self‐perceptions and mental health in NEET 18‐year olds from a contemporary British cohort 下载免费PDF全文
Sidra Goldman‐Mellor Avshalom Caspi Louise Arseneault Nifemi Ajala Antony Ambler Andrea Danese Helen Fisher Abigail Hucker Candice Odgers Teresa Williams Chloe Wong Terrie E. Moffitt 《Journal of child psychology and psychiatry, and allied disciplines》2016,57(2):196-203
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The genetic diversity of Epstein–Barr virus in the setting of transplantation relative to non‐transplant settings: A feasibility study 下载免费PDF全文
Pingzhao Hu Sergio L. Pereira Joan L. Robinson Tara A. Paton Joseph Beyene Nasser Khodai‐Booran Anne Dipchand Diane Hébert Vicky Ng Thomas Nalpathamkalam Stanley Read 《Pediatric transplantation》2016,20(1):124-129
This study examines EBV strains from transplant patients and patients with IM by sequencing major EBV genes. We also used NGS to detect EBV DNA within total genomic DNA, and to evaluate its genetic variation. Sanger sequencing of major EBV genes was used to compare SNVs from samples taken from transplant patients vs. patients with IM. We sequenced EBV DNA from a healthy EBV‐seropositive individual on a HiSeq 2000 instrument. Data were mapped to the EBV reference genomes (AG876 and B95‐8). The number of EBNA2 SNVs was higher than for EBNA1 and the other genes sequenced within comparable reference coordinates. For EBNA2, there was a median of 15 SNV among transplant samples compared with 10 among IM samples (p = 0.036). EBNA1 showed little variation between samples. For NGS, we identified 640 and 892 variants at an unadjusted p value of 5 × 10?8 for AG876 and B95‐8 genomes, respectively. We used complementary sequence strategies to examine EBV genetic diversity and its application to transplantation. The results provide the framework for further characterization of EBV strains and related outcomes after organ transplantation. 相似文献
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Health‐related correlates of psychological well‐being among girls and boys 6–8 years of age: The Physical Activity and Nutrition in Children study 下载免费PDF全文
Tiina Ikävalko Soili Lehto Niina Lintu Juuso Väistö Aino‐Maija Eloranta Eero A Haapala Anu Vierola Riitta Myllykangas Henri Tuomilehto Soren Brage Riitta Pahkala Matti Närhi Timo A Lakka 《Journal of paediatrics and child health》2018,54(5):506-509